Part 10: KE enrichment analysis and benchmarking for dataset: GSE44729
The AOP project ► Key objective 2
Author: Shakira Agata
This Jupyter Notebook shows the steps for the execution of KE enrichment analysis and benchmarking to Overrepresentation Analysis(ORA) for dataset: GSE44729 This notebook is subdivided into nine sections:
- Section 1: Creation of dictKE dictionary
- Section 2: Creation of dictWP dictionary
- Section 3: Creation of KEgenes dictionary
- Section 4: Calculation of N variable
- Section 5: Comparison 1: Acrolein timepoint 2
- Section 5.1: Calculation of n variable
- Section 5.2:Calculation of variable B and variable b
- Section 5.3: Calculation of enrichment score & hypergeometric p-value
- Section 5.4: Filtering results
- Section 5.5: Calculation of percent gene overlap
- Section 5.5.1 Creation of significant KE table
- Section 5.5.2 Significant ORA pathway table
- Section 5.5.3 Creation of for loop
- Section 5.5.4 Tabulation
- Section 5.5.5 Percent overlap calculation
- Section 6: Comparison 2: Chloropicrin timepoint 1
- Section 6.1: Calculation of n variable
- Section 6.2:Calculation of variable B and variable b
- Section 6.3: Calculation of enrichment score & hypergeometric p-value
- Section 6.4: Filtering results
- Section 6.5: Calculation of percent gene overlap
- Section 6.5.1 Creation of significant KE table
- Section 6.5.2 Significant ORA pathway table
- Section 6.5.3 Creation of for loop
- Section 6.5.4 Tabulation
- Section 6.5.5 Percent overlap calculation
- Section 7: Comparison 3: Chloropicrin timepoint 2
- Section 7.1: Calculation of n variable
- Section 7.2:Calculation of variable B and variable b
- Section 7.3: Calculation of enrichment score & hypergeometric p-value
- Section 7.4: Filtering results
- Section 7.5: Calculation of percent gene overlap
- Section 7.5.1 Creation of significant KE table
- Section 7.5.2 Significant ORA pathway table
- Section 7.5.3 Creation of for loop
- Section 7.5.4 Tabulation
- Section 7.5.5 Percent overlap calculation
- Section 8: Comparison 4: Maleic anhydride timepoint 2
- Section 8.1: Calculation of n variable
- Section 8.2:Calculation of variable B and variable b
- Section 8.3: Calculation of enrichment score & hypergeometric p-value
- Section 8.4: Filtering results
- Section 8.5: Calculation of percent gene overlap
- Section 8.5.1 Creation of significant KE table
- Section 8.5.2 Significant ORA pathway table
- Section 8.5.3 Creation of for loop
- Section 8.5.4 Tabulation
- Section 8.5.5 Percent overlap calculation
- Section 9: Metadata
Section 1: Creation of dictKE dictionary
In this section, the dictKE dictionary will be made which is used to retrieve the first neighbors of the key events present in the inflammatory stress response pathway AOP network.
Step 1. First, the necessary packages and inflammatory stress response pathway AOP network were loaded.
import pandas as pd
import numpy as np
from scipy.stats import hypergeom
import matplotlib.pyplot as plt
import scipy.stats as ss
import py4cytoscape as p4c
p4c.cytoscape_ping()
p4c.cytoscape_version_info()
You are connected to Cytoscape!
{'apiVersion': 'v1',
'cytoscapeVersion': '3.10.1',
'automationAPIVersion': '1.9.0',
'py4cytoscapeVersion': '1.9.0'}
network=p4c.open_session('Agata,S.-Part4 Complete Molecular inflammation-process related AOP network.cys')
Opening C:\Users\shaki\Downloads\Agata,S.-Part4 Complete Molecular inflammation-process related AOP network.cys...
Step 2. Next, the nodetable and the original nodetable derived from the KE-WP mapping results are loaded.
nodetable=p4c.get_table_columns()
dataframe_for_dictKE=pd.read_excel('Nodetable-dictKE.xlsx')
df_corrected=pd.read_excel('nodetable-dictWP.xlsx').reset_index(drop=True)
Step 3. The dataframe will now be converted into a dictionary where the keys are the IDs from the key events and the values are the titles of the molecular pathways.
completedataframe_for_dictKE=dataframe_for_dictKE[['ID (KEID)','WPtitle']].copy()
complete_dataframe_for_dictKE=completedataframe_for_dictKE.rename(columns={"ID (KEID)":"KEID"})
Step 4. The format of the dataframe will now be converted into a dictionary format.
dictKE= complete_dataframe_for_dictKE.to_dict('records')
Section 2: Creation of dictWP dictionary
In this section, the dictWP dictionary will be created. The dictWP dictionary will contain the first neighbours: genes of the individual molecular pathways mapped to the inflammatory stress response pathway AOP network.
Step 5. First, the dataframe is created in which the molecular pathways mapped to the network are filtered.
df4= nodetable[nodetable['type'] == 'Molecular pathway']
Step 6. A duplicate network will be created for which we will create filters to only contain gene and molecular pathway nodes in the network in preparation for the dictWP creation. This requires a composite filter to exclude Molecular Initiating Event (MIE) nodes, Key Event (KE) nodes and Adverse Outcome (AO) nodes.
Clonednetwork_fordictWP= p4c.clone_network()
p4c.rename_network('Cloned molecular inflammatory stress response pathway AOP network for dict WP')
{'network': 132,
'title': 'Cloned molecular inflammatory stress response pathway AOP network for dict WP'}
MIEfilter= p4c.create_column_filter('MIE filter', 'type', 'MIE', 'CONTAINS', network='Cloned molecular inflammatory stress response pathway AOP network for dict WP')
No edges selected.
KEfilter= p4c.create_column_filter('KE filter', 'type', 'KE', 'CONTAINS',network='Cloned molecular inflammatory stress response pathway AOP network for dict WP')
No edges selected.
AOfilter= p4c.create_column_filter('AO filter', 'type', 'AO', 'CONTAINS',network='Cloned molecular inflammatory stress response pathway AOP network for dict WP')
No edges selected.
combined_MIEKEAOfilter= p4c.create_composite_filter('MIE KE AO filter', ['MIE filter','KE filter','AO filter'],type='ANY',network='Cloned molecular inflammatory stress response pathway AOP network for dict WP')
No edges selected.
Step 7. You will delete the selected filtered nodes from the composite filter to only maintain the molecular pathway nodes and gene nodes.
Deletednodes= p4c.delete_selected_nodes(network='Cloned molecular inflammatory stress response pathway AOP network for dict WP')
Step 8. A for loop will be created for the WP dictionary which contains the WP titles as the keys and the names of the genes as values. Due to settings of the get_first_neighbours function, it is not possible to retrieve the gene IDs with this function.
name_list_WP=df_corrected['name'].tolist()
dictWP = {}
for name in name_list_WP:
gene_neighbors_per_WP = p4c.get_first_neighbors(node_names=name, network= 'Cloned molecular inflammatory stress response pathway AOP network for dict WP', as_nested_list=False)
dictWP[name] = gene_neighbors_per_WP
print(dictWP)
{'Overview of proinflammatory and profibrotic mediators': ['IL25', 'IL12A', 'CXCL8', 'IL13', 'CSF1', 'IFNL2', 'IL17D', 'IFNL1', 'IL3', 'CSF2', 'CXCL1', 'CXCL5', 'IL1B', 'IL17C', 'IL17B', 'IL10', 'IL6', 'IFNG', 'IL17A', 'VEGFA', 'IL17F', 'IL23A', 'IL12B', 'IL5', 'IL4', 'CCL20', 'MMP9', 'TGFB1', 'CXCL12', 'CCL2', 'IL2', 'CCL3L1', 'CCL28', 'CTF1', 'IL33', 'CCL1', 'SPP1', 'EPO', 'LIF', 'MMP3', 'PF4', 'PPBP', 'LTA', 'EBI3', 'CSF3', 'CXCL2', 'IL7', 'OSM', 'IL22', 'CCL27', 'IL31', 'CCL15', 'CNTF', 'CXCL11', 'CXCL3', 'IL18', 'CXCL16', 'CXCL13', 'TNFSF13', 'AREG', 'IL1A', 'IL11', 'CCL22', 'TNFSF13B', 'CCL8', 'CXCL9', 'IL21', 'IL9', 'CXCL6', 'CCL21', 'NFKB1', 'CCL26', 'IFNL3', 'TNF', 'CCL5', 'IL26', 'CCL18', 'CCL4L2', 'CCL14', 'IFNW1', 'CCL13', 'IFNK', 'TSLP', 'IL24', 'IL20', 'CCL16', 'CCL23', 'CXCL17', 'IL36RN', 'IL36A', 'IL1F10', 'IL36B', 'XCL2', 'IL37', 'IL36G', 'PF4V1', 'CCL11', 'MMP1', 'IFNB1', 'CXCL10', 'IFNA7', 'CCL3', 'CCL4', 'IL27', 'IFNA14', 'IFNA1', 'IFNA17', 'IFNA13', 'IFNA4', 'IFNA5', 'IFNA16', 'IFNA2', 'IFNA10', 'IL19', 'IL15', 'IFNA6', 'IFNA8', 'IFNA21', 'IL1RN', 'XCL1', 'CXCL14', 'CCL19', 'CCL25', 'CCL7', 'CCL24', 'CX3CL1', 'CCL17'], 'Cytosolic DNA-sensing pathway': ['CASP1', 'RIPK1', 'IL6', 'RIPK3', 'IRF3', 'IL1B', 'NFKBIA', 'POLR2F', 'POLR2E', 'IKBKB', 'TRADD', 'ATG5', 'CASP10', 'CASP8', 'NLRX1', 'AIM2', 'NFKBIB', 'NFKB1', 'CCL5', 'CHUK', 'IRF7', 'IKBKG', 'IKBKE', 'TBK1', 'POLR2L', 'POLR2K', 'ATG12', 'FADD', 'POLR2H', 'IL18', 'PYCARD', 'ADAR', 'STING1', 'POLR1C', 'CGAS', 'POLR3F', 'IL33', 'MAVS', 'POLR3GL', 'TRIM25', 'POLR3G', 'DDX58', 'POLR3H', 'POLR3E', 'POLR3B', 'CYLD', 'IFNB1', 'IFNA7', 'RELA', 'CCL4', 'ISG15', 'POLR1D', 'POLR3C', 'CXCL10', 'POLR3D', 'POLR3K', 'POLR3A', 'CCL4L2', 'ZBP1', 'RNF125', 'IFNA8', 'IFNA6', 'IFNA21', 'IFNA17', 'IFNA16', 'IFNA14', 'IFNA13', 'IFNA10', 'IFNA4', 'IFNA2', 'IFNA1', 'IFNA5', 'TREX1'], 'miRNA regulation of DNA damage response': ['BID', 'BRCA1', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'CDKN1A', 'RAD52', 'PRKDC', 'PML', 'RPA2', 'RAD50', 'CASP3', 'PMAIP1', 'FANCD2', 'CHEK1', 'ATM', 'RAD17', 'CASP9', 'TP53', 'CDK4', 'MDM2', 'TNFRSF10B', 'CDK2', 'CCND2', 'APAF1', 'CDKN1B', 'RAD1', 'CCNG1', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CHEK2', 'H2AX', 'ATR', 'RAD9A', 'PIDD1', 'MYC', 'MRE11', 'NBN', 'MIR29B1', 'MIR145', 'CREB1', 'CDK1', 'CYCS', 'MIR421', 'MIR449A', 'MIR373', 'MIR222', 'MIR449B', 'MIR3591', 'ATRIP', 'TP53AIP1', 'CCNB3', 'TLK2', 'HUS1B', 'RFC1', 'E2F1', 'CCNB1', 'RB1', 'DDB2', 'CCNE2', 'CDK6', 'CCND3', 'CCNB2', 'GADD45A', 'CDK5', 'CDC25C', 'MIR34B', 'MIR21', 'MIR29C', 'MCM7', 'MIR20A', 'MIR106B', 'MIR17HG', 'MIR195', 'MIR424', 'MIR17', 'CDC20B', 'MIR330', 'MIR221', 'MIR16-1', 'MIR203A', 'MIR181A1', 'MIR223', 'MIR15A', 'MIR29A', 'MIR24-1', 'TLK1', 'SFN', 'MIR210', 'GADD45G', 'RRM2B', 'SESN1', 'GADD45B', 'CDC25A'], 'miRNAs involved in DNA damage response': ['CDKN1A', 'MIR92A1', 'MIR18A', 'MYC', 'ATM', 'ABL1', 'H2AX', 'MIR145', 'MIR29B1', 'CREB1', 'CDKN1B', 'MIR143', 'CCNE1', 'TP53', 'RAD52', 'CCND1', 'MIRLET7D', 'MIRLET7F1', 'MIR34C', 'MIRLET7A1', 'MIR23B', 'MIR20A', 'MIR106B', 'MIR424', 'MIR195', 'MIR330', 'MIR17', 'MIR449B', 'MIR222', 'MIR181B1', 'MIR449A', 'MIR421', 'MIR373', 'E2F1', 'MIRLET7B', 'CDK6', 'MIR34B', 'MIR29C', 'MIR21', 'CCND3', 'CDC25A', 'MIR449C', 'MIR19B1', 'MIR100', 'MIR542', 'MIR374B', 'MIR503', 'MIR450B', 'MIR19A', 'MIR497', 'MIR3074', 'MIR450A2', 'MIR25', 'MIR93', 'MIR372', 'MIR371A', 'MIR210', 'MIR181A1', 'MIR203A', 'MIR27A', 'MIR223', 'MIR29A', 'MIR23A', 'MIR221', 'MIR15A', 'MIR16-1', 'MIR27B', 'MIR15B'], 'Neuroinflammation and glutamatergic signaling': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1'], 'Electron transport chain: OXPHOS system in mitochondria': ['SLC25A6', 'SLC25A14', 'SLC25A27', 'MT-ND3', 'MT-ND4', 'MT-ND6', 'UCP3', 'MT-ND4L', 'MT-ND5', 'MT-ND2', 'COX11', 'COX8A', 'SDHA', 'COX5A', 'SDHC', 'SDHD', 'ATP5IF1', 'NDUFA11', 'NDUFA1', 'COX7A2', 'UQCRQ', 'COX6A2', 'COX7A1', 'NDUFS7', 'MT-CYB', 'UQCR10', 'NDUFA2', 'NDUFA3', 'NDUFA7', 'NDUFA8', 'NDUFA5', 'NDUFA6', 'NDUFB1', 'NDUFB2', 'NDUFA9', 'NDUFA10', 'UQCR11', 'MT-ND1', 'SLC25A5', 'COX17', 'COX7A2L', 'MT-CO2', 'MT-CO3', 'SCO1', 'NDUFA4', 'UQCRFS1', 'SURF1', 'UCP2', 'COX4I1', 'COX6B1', 'COX6C', 'COX5B', 'COX6A1', 'COX7B', 'COX7C', 'MT-CO1', 'UCP1', 'NDUFA13', 'SLC25A4', 'UQCRB', 'UQCRH', 'UQCRC1', 'UQCRC2', 'NDUFB4', 'NDUFB5', 'NDUFB3', 'NDUFB8', 'NDUFB10', 'NDUFB6', 'NDUFB7', 'NDUFS1', 'NDUFC1', 'NDUFC2', 'NDUFV1', 'NDUFS4', 'NDUFS2', 'NDUFS3', 'NDUFS8', 'NDUFV2', 'NDUFS5', 'NDUFS6', 'NDUFV3', 'NDUFA12', 'ATP5MF', 'NDUFB9', 'DMAC2L', 'ATP5F1E', 'MT-ATP8', 'MT-ATP6', 'NDUFAB1', 'ATP5F1B', 'ATP5F1A', 'ATP5F1D', 'ATP5F1C', 'ATP5MC1', 'ATP5PB', 'ATP5MC3', 'ATP5MC2', 'ATP5PF', 'ATP5ME', 'ATP5PO', 'COX15', 'ATP5MG', 'ATP5PD', 'SDHB'], 'TLR4 signaling and tolerance': ['TRAM1', 'TIRAP', 'TLR4', 'IL6', 'IRF3', 'TRAF3', 'NFKB1', 'TAB2', 'TAB1', 'MYD88', 'TRAF6', 'RIPK1', 'IKBKE', 'CXCL8', 'NFKBIA', 'TICAM1', 'IKBKG', 'IRAK3', 'TNF', 'CHUK', 'IKBKB', 'MAP3K7', 'IRAK4', 'IRAK1', 'TBK1', 'IRF7', 'INPP5D', 'IFNB1'], 'Toll-like receptor signaling': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5'], 'Nod-like receptor (NLR) signaling': ['ERBIN', 'CHUK', 'IKBKB', 'MAPK8', 'MAP3K7', 'IKBKG', 'CD40', 'EPHB2', 'RELA'], 'NRF2 pathway': ['SLC6A20', 'SLC6A18', 'FTH1', 'GSTM4', 'SLC39A2', 'SLC39A13', 'SLC6A5', 'SLC5A10', 'SLC7A11', 'SLC2A13', 'SLC6A1', 'CBR3', 'CES5A', 'SLC5A11', 'CBR1', 'SLC2A6', 'SLC39A3', 'SLC2A5', 'MGST3', 'SLC39A6', 'SLC39A1', 'SLC2A12', 'SLC39A4', 'SLC39A12', 'SLC5A12', 'GSTA5', 'GPX2', 'ADH7', 'SLC6A9', 'MAFF', 'CYP4A11', 'GSTA4', 'SLC6A19', 'GSTA3', 'CES3', 'CES2', 'SLC2A14', 'CES4A', 'GCLC', 'UGT1A7', 'UGT1A4', 'CYP2A6', 'SLC5A8', 'SLC6A14', 'SRXN1', 'MAFG', 'SLC6A17', 'SLC2A7', 'SLC39A10', 'SLC2A10', 'TXNRD3', 'CES1', 'AGER', 'TXNRD1', 'SLC5A3', 'GPX3', 'SLC2A3', 'HGF', 'HMOX1', 'PDGFB', 'KEAP1', 'SERPINA1', 'UGT1A1', 'GSTA1', 'GSTA2', 'GSTM2', 'TGFBR2', 'SLC2A2', 'UGT1A6', 'UGT2B7', 'NQO1', 'FGF13', 'GSTM1', 'EPHA2', 'TXN', 'NRG1', 'SLC5A5', 'ABCC3', 'NFE2L2', 'ABCC4', 'HSP90AA1', 'HSP90AB1', 'TGFB2', 'UGT1A9', 'ABCC2', 'RXRA', 'SLC2A4', 'HSPA1A', 'G6PD', 'PGD', 'SLC6A3', 'TGFA', 'SQSTM1', 'SLC2A1', 'SLC5A7', 'HBEGF', 'TGFB1', 'SLC6A2', 'SLC39A14', 'GSR', 'SLC5A1', 'GGT1', 'GSTT2', 'SLC5A4', 'BLVRB', 'SLC39A9', 'EPHA3', 'SLC6A16', 'ME1', 'SLC6A15', 'SLC6A7', 'SLC6A13', 'GCLM', 'MGST2', 'GSTP1', 'FTL', 'SLC39A8', 'SLC5A6', 'SLC2A8', 'SLC5A2', 'SLC39A5', 'SLC6A6', 'SLC6A8', 'SLC6A11', 'DNAJB1', 'SLC2A11', 'SLC39A11', 'GSTM3', 'GSTM5', 'SLC5A9', 'PRDX6', 'PRDX1', 'EGR1', 'SLC2A9', 'SOD3', 'ALDH3A1', 'SLC6A4', 'PTGR1', 'ABCC5', 'SLC39A7', 'PPARD'], 'Cellular proteostasis': ['PFDN6', 'VBP1', 'PFDN2', 'PFDN1', 'PFDN5', 'PFDN4'], 'Unfolded protein response': ['MBTPS1', 'ATF4', 'MBTPS2', 'NFE2L2', 'HSPA5', 'PPP1R15A', 'XBP1', 'ATF6', 'EIF2S1', 'ERN1', 'DDIT3', 'EIF2AK3', 'BBC3', 'TNFRSF10B', 'IL1B', 'TP53', 'PMAIP1', 'BID', 'TXNIP', 'BCL2L11', 'BCL2', 'RTCB', 'CASP2'], 'Oxidative phosphorylation': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10'], 'Soluble ACE2-mediated cell entry of SARS-CoV-2': ['AVPR1B', 'ACE2', 'AGTR1', 'ADAM17'], 'DNA damage response (only ATM dependent)': ['FRAT1', 'LDLR', 'FOSL1', 'CDKN1A', 'BAD', 'BAK1', 'MAPK9', 'MAP3K1', 'ABL1', 'BIK', 'SOS2', 'MAP3K4', 'BAX', 'MAPK8', 'CDKN1B', 'TGFB1', 'FASLG', 'FOXO3', 'CAT', 'RAC2', 'SOS1', 'MDM2', 'RAC1', 'MAP3K7', 'G6PC1', 'PMAIP1', 'ATM', 'BCL2L11', 'TP53', 'SMAD4', 'SHC1', 'IRS1', 'HMGB1', 'INSR', 'BCL2', 'AKT2', 'AKT3', 'AKT1', 'RAC3', 'BBC3', 'CDKN2A', 'NFKB1', 'GSK3B', 'PIK3R4', 'HRAS', 'JUN', 'RHOA', 'MYC', 'CTNNB1', 'PIK3C2G', 'PIK3C3', 'PIK3CA', 'PIK3CB', 'PIK3CD', 'PIK3CG', 'PIK3R1', 'PIK3R2', 'NRAS', 'WNT16', 'PIK3C2A', 'CCND1', 'WNT1', 'WNT5A', 'WNT10B', 'AXIN1', 'PIK3R3', 'CCND2', 'MAPK10', 'PPP2R5C', 'MAPK1', 'PCK2', 'CCNG2', 'MLKL', 'LEF1', 'TCF7', 'TCF7L2', 'TCF7L1', 'CCND3', 'CDC42', 'APC', 'ERBB2', 'PDK1', 'SMAD3', 'PTEN', 'GRB2', 'NFKB2', 'DVL1', 'DVL2', 'DVL3', 'PIK3R5', 'PPP2R5E', 'WNT2', 'KRAS', 'PIK3C2B', 'PLAU', 'WNT4', 'WNT10A', 'WNT5B', 'WNT3A', 'WNT3', 'WNT6', 'WNT7A', 'WNT7B', 'WNT11', 'WNT2B', 'RBL2', 'TP73', 'BCL6', 'SCP2'], 'DNA damage response': ['PML', 'PRKDC', 'CDKN1A', 'RAD52', 'BRCA1', 'BID', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'MRE11', 'MYC', 'NBN', 'PIDD1', 'RFC1', 'ATRIP', 'TP53AIP1', 'TLK2', 'CCNB3', 'HUS1B', 'CHEK1', 'RAD17', 'CASP3', 'CDK1', 'CYCS', 'RAD9A', 'ATR', 'CHEK2', 'H2AX', 'CREB1', 'TNFRSF10B', 'CDK2', 'CASP9', 'CDK4', 'MDM2', 'TP53', 'PMAIP1', 'AKT1', 'FANCD2', 'ATM', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CDKN1B', 'RAD1', 'RAD50', 'RPA2', 'CCND2', 'APAF1', 'RB1', 'CCNE2', 'CCNB2', 'CDC25C', 'CDK5', 'CDK6', 'CCND3', 'GADD45A', 'CCNB1', 'DDB2', 'E2F1', 'GADD45G', 'CDC25A', 'TLK1', 'GADD45B', 'SFN', 'RRM2B', 'SESN1'], 'NRF2-ARE regulation': ['GSK3B', 'SRC', 'PRKCA', 'MAPK8', 'PIK3CA', 'INSR', 'CEBPB', 'FYN', 'MAF', 'SLC7A11', 'GCLM', 'RBX1', 'CUL3', 'AIMP2', 'YES1', 'KEAP1', 'NFE2L2', 'GCLC', 'EPHB2', 'NQO1', 'HMOX1', 'GSTA2', 'PGAM5'], 'Canonical NF-kB pathway': ['NFKB1', 'NFKBIA', 'IKBKB', 'NFKBIE', 'CHUK', 'IKBKG', 'RELA', 'REL'], '-': [], 'Mitochondrial complex I assembly model OXPHOS system': ['NDUFAF1', 'NDUFB9', 'ACAD9', 'NDUFAB1', 'ECSIT', 'COA1', 'TIMMDC1', 'FOXRED1', 'DMAC1', 'NDUFAF3', 'TMEM70', 'NUBPL', 'TMEM186', 'MT-ND6', 'NDUFAF6', 'NDUFAF7', 'TMEM126B', 'MT-ND2', 'MT-ND4L', 'MT-ND4', 'MT-ND5', 'DMAC2', 'NDUFAF4', 'NDUFA2', 'NDUFS5', 'NDUFS2', 'NDUFS6', 'NDUFS4', 'NDUFB5', 'NDUFB3', 'NDUFC1', 'NDUFA1', 'NDUFB1', 'MT-ND1', 'NDUFAF2', 'NDUFA13', 'NDUFB11', 'NDUFA12', 'NDUFA8', 'NDUFV3', 'NDUFA6', 'NDUFA5', 'NDUFB7', 'NDUFV2', 'NDUFS1', 'NDUFV1', 'NDUFC2', 'NDUFA10', 'NDUFB10', 'NDUFB4', 'NDUFB8', 'NDUFB2', 'NDUFA7', 'NDUFS3', 'NDUFB6', 'NDUFA3'], 'Downregulation of ACE2 by SARS-CoV-2 spike protein': ['ACE', 'AGTR1', 'AGTR2', 'ACE2'], 'PPAR signaling': ['ACAA1', 'ACOX3', 'ACSL4', 'NR1H3', 'SCD', 'CPT1B', 'SLC27A6', 'FABP1', 'DBI', 'ACSBG1', 'HMGCS2', 'APOA5', 'ADIPOQ', 'ACSL1', 'LPL', 'CYP7A1', 'CD36', 'PDPK1', 'FADS2', 'RXRA', 'PCK1', 'CYP4A11', 'APOA2', 'ACSBG2', 'PPARD', 'ME1', 'ACADL', 'EHHADH', 'ACSL3', 'PLTP', 'PCK2', 'ILK', 'AQP7', 'ACOX2', 'PLIN1', 'FABP6', 'PPARA', 'CYP8B1', 'MMP1', 'UCP1', 'ACADM', 'APOA1', 'PPARG', 'CYP27A1', 'SLC27A2', 'SLC27A5', 'GK3P', 'FABP5', 'OLR1', 'APOC3', 'CPT1A', 'RXRB', 'RXRG', 'SLC27A4', 'FABP4', 'ACOX1', 'FABP2', 'ANGPTL4', 'ACSL6', 'ACSL5', 'CPT2', 'GK2', 'SCP2', 'SLC27A1', 'FABP3', 'SORBS1', 'CPT1C', 'FABP7'], 'AMP-activated protein kinase signaling': ['GYS1', 'AKT2', 'RPS6KB1', 'PIK3R2', 'PIK3CG', 'ADRA1A', 'PIK3CA', 'CAMKK2', 'PIK3R3', 'CCNA1', 'CCNA2', 'PIK3R1', 'TP53', 'AKT1', 'INSR', 'TSC1', 'FASN', 'ADIPOQ', 'CPT1B', 'TSC2', 'CDKN1A', 'SREBF1', 'PIK3C3', 'CAMKK1', 'PIK3CB', 'EEF2K', 'ADRA1B', 'MTOR', 'EIF4EBP1', 'HMGCR', 'LEP', 'RPS6KB2', 'PIK3CD', 'SLC2A4', 'PRKAA2', 'PRKAB1', 'PRKAG3', 'PRKAA1', 'PRKAB2', 'PRKAG2', 'RPTOR', 'PRKAG1', 'CPT1A', 'STRADB', 'CAB39', 'PFKFB3', 'PRKACB', 'PRKACG', 'ACACA', 'ELAVL1', 'LIPE', 'STK11', 'CCNB1', 'GYS2', 'PPARGC1B', 'PLCB1', 'STRADA', 'CRTC2', 'HNF4A', 'LEPR', 'ACACB', 'EEF2', 'ADIPOR2', 'INS-IGF2', 'ADIPOR1', 'CPT1C', 'SLC2A4RG'], 'Cholestasis': ['ATP8B1', 'HMGCR', 'LDLR', 'ABCC2', 'SCARB1', 'ABCG8', 'RXRA', 'TJP2', 'ABCG5', 'SLC22A1', 'ABCB4', 'NR1I3', 'SLC10A1', 'NR1H4', 'SLCO1A2', 'EPHX1', 'ABCC3', 'ABCB11', 'ABCC4'], 'Farnesoid X receptor pathway': ['UGT2B4', 'IRS2', 'SLC27A5', 'CYP8B1', 'IP6K3', 'ABCB4', 'NR0B2', 'SULT2A1', 'NR1H4', 'FGF19', 'BAAT', 'SLC10A1', 'ABCB11', 'SLCO2B1', 'RXRA', 'CYP7A1', 'CYP3A4', 'PPARGC1A', 'FKBP5'], 'BDNF-TrkB signaling': ['EIF4EBP1', 'EEF2K', 'MTOR', 'MKNK1', 'DLG4', 'TRPC6', 'TRPC3', 'TSC2', 'MAPK1', 'PIK3CG', 'RHEB', 'RPS6KB1', 'RPS6KA1', 'CREB1', 'SOS1', 'SHC1', 'AKT1', 'HRAS', 'BDNF', 'TSC1', 'MAP2K1', 'NRAS', 'ARC', 'GAB1', 'GAB2', 'KRAS', 'NTRK2', 'PLCG1', 'ADCY1', 'GRIN1', 'GRB2', 'BRAF', 'HOMER1'], 'EGF/EGFR signaling': ['IQSEC1', 'USP6NL', 'EPS8', 'REPS2', 'ATXN2', 'ERRFI1', 'MYBL2', 'CDC42', 'GAB2', 'RIN1', 'HGS', 'USP8', 'IQGAP1', 'STAM', 'RAB5A', 'PTK2', 'PTEN', 'PRKCZ', 'PLD2', 'PLD1', 'PLCG1', 'PIK3C2B', 'PLCE1', 'TWIST1', 'AURKA', 'STAT5B', 'STAT5A', 'BRAF', 'RAP1A', 'RALGDS', 'RALB', 'RALA', 'DNM1', 'RALBP1', 'CFL1', 'STAMBP', 'EGF', 'E2F1', 'NEDD8', 'NCK1', 'FOXO4', 'STMN1', 'KRAS', 'ARF6', 'GRB2', 'NOS3', 'GAB1', 'PIAS3', 'STAM2', 'INPP5D', 'AP2B1', 'AP2A1', 'AP2S1', 'SPRY2', 'PXDN', 'STXBP1', 'NDUFA13', 'PEBP1', 'NEDD4', 'LIMK2', 'SH3KBP1', 'EPS15L1', 'INPPL1', 'EPN1', 'EPS15', 'ABI1', 'AP2M1', 'PRKCI', 'MT-CO2', 'DOK2', 'PLSCR1', 'ASAP1', 'MTOR', 'EIF4EBP1', 'CSK', 'PTK2B', 'MAP3K3', 'MAP3K1', 'PAK1', 'MAP3K4', 'MEF2A', 'MEF2D', 'MEF2C', 'PDPK1', 'PCNA', 'MAPK1', 'PRKCB', 'MAPK7', 'MAPK4', 'PIK3R2', 'PIK3R1', 'PRKCA', 'MAPK8', 'MAPK14', 'ELK1', 'EGFR', 'CRK', 'CREB1', 'FOXO1', 'AKT1', 'FOS', 'GJA1', 'RICTOR', 'JAK1', 'HRAS', 'FOSB', 'ABL1', 'CBLC', 'JUN', 'JAK2', 'JUND', 'MAP4K1', 'MAP3K2', 'VAV3', 'PTPN5', 'PTPRR', 'ARHGEF1', 'SH3GL2', 'RASA1', 'RAF1', 'RPS6KA1', 'PTK6', 'MAP2K5', 'RAC1', 'PTPN11', 'MAPK9', 'MAP2K2', 'MAP2K1', 'STAT3', 'STAT1', 'SOS2', 'SOS1', 'SRC', 'SP1', 'RPS6KA3', 'RPS6KA2', 'SHC1', 'RPS6KB1', 'NCK2', 'ITCH', 'CAV2', 'CAV1', 'ATF1', 'ROCK1', 'PRKCD', 'SYNJ1', 'CRKL', 'ERBB2', 'ELK4', 'TNK2', 'GRB10', 'PTPN12', 'SH2D2A', 'SH3GL3', 'BCAR1', 'CBL', 'RPS6KA5', 'CBLB', 'VAV2', 'VAV1', 'NCOA3', 'CAMK2A'], 'Glutathione metabolism': ['GPX4', 'IDH1', 'GGT1', 'G6PD', 'GPX1', 'GPX2', 'GPX3', 'GSTA5', 'GCLM', 'GSR', 'GSTT2', 'GSTA1', 'GSTM1', 'GCLC', 'GSTM2', 'GGT5', 'OPLAH', 'ANPEP', 'GSS'], 'Apoptosis': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1'], 'Cholesterol biosynthesis pathway in hepatocytes': ['ABCG1', 'HMGCS1', 'CYP51A1', 'ACOT1', 'ELOVL3', 'ELOVL2', 'HMGCS2', 'NR1H2', 'SC5D', 'GGPS1', 'ACAT2', 'NSDHL', 'HSD17B7', 'LSS', 'PMVK', 'EBP', 'FDFT1', 'LBR', 'TM7SF2', 'IDI1', 'HMGCR', 'ELOVL4', 'SCD', 'MVD', 'CYP7A1', 'SREBF1', 'ACSL1', 'FADS2', 'IDI2', 'CYP27A1', 'CH25H', 'ABCA1', 'MYLIP', 'ACSL3', 'ELOVL5', 'MVK', 'NR1H3', 'FDPS', 'CYP46A1', 'MSMO1', 'ACOT2', 'DHCR24', 'PLPP6'], 'Focal adhesion: PI3K-Akt-mTOR-signaling': ['MTOR', 'EIF4EBP1', 'ITGB8', 'PIK3CG', 'COMP', 'PIK3R2', 'PPP2R1A', 'RHEB', 'JAK2', 'HSP90AB1', 'ITGA6', 'HIF1A', 'IL2RB', 'MAPK1', 'GYS1', 'PPP2CB', 'IKBKB', 'TSC2', 'MAPK3', 'AKT2', 'LAMC2', 'PIK3CB', 'GNB1', 'PPP2R5C', 'IL4R', 'SREBF1', 'ITGB5', 'GSK3B', 'HSP90AA1', 'LAMB1', 'IGF1', 'PIK3C2A', 'BAD', 'CDKN1A', 'TSC1', 'VEGFD', 'COL1A2', 'JAK1', 'PRKAA2', 'GNG8', 'GNGT2', 'RPTOR', 'EGFR', 'PIK3R1', 'AKT1', 'EIF4E', 'FOXO1', 'VEGFC', 'ITGB1', 'IL2RG', 'GNG3', 'ITGB2', 'CASP9', 'ITGB4', 'LAMC1', 'MDM2', 'IL2RA', 'NGF', 'IRS4', 'THBS1', 'PPP2R1B', 'RPS6', 'PDPK1', 'ITGB7', 'PIK3CA', 'FOXO3', 'GNG11', 'GNG13', 'PRKAA1', 'RAF1', 'LAMA5', 'FOXA1', 'GNGT1', 'MAP2K2', 'ITGB6', 'GNB4', 'PPP2CA', 'VEGFA', 'GNB3', 'CDKN1B', 'PPARGC1A', 'IL2', 'CREB1', 'SLC2A1', 'AKT3', 'EPAS1', 'ATF2', 'SOS1', 'FN1', 'VTN', 'COL1A1', 'RPS6KB1', 'FGF8', 'COL3A1', 'GNG4', 'MLST8', 'IKBKG', 'ITGB3', 'INS', 'GNG10', 'NRAS', 'ULK1', 'GNG7', 'RPS6KB2', 'HRAS', 'GNG5', 'SLC2A4', 'PIK3R4', 'GNG2', 'IRS2', 'CSF1', 'F2R', 'INSR', 'THBS3', 'IRS1', 'MAP2K1', 'VEGFB', 'GNG12', 'GNB2', 'PRL', 'LAMB2', 'PIK3CD', 'FGF4', 'PPP2R2C', 'PPP2R3A', 'FGF22', 'FGF10', 'ITGAE', 'PHLPP1', 'COL4A4', 'COL5A3', 'LIPE', 'FGF20', 'ITGA8', 'FGFR1', 'COL11A1', 'CREB3L3', 'SLC2A3', 'LAMA3', 'LAMC3', 'KITLG', 'TNC', 'PHLPP2', 'EIF4B', 'FLT4', 'PPP2R5B', 'FGFR3', 'FGFR2', 'ELAVL1', 'PPP2R5A', 'TBC1D1', 'LPAR2', 'NGFR', 'NOS2', 'ITGA2B', 'ITGA3', 'ITGAL', 'IBSP', 'HGF', 'CDC37', 'RAB2A', 'CREB3', 'MET', 'JAK3', 'FGF21', 'CSF3', 'GYS2', 'FGF6', 'VWF', 'ITGA10', 'EPHA2', 'COL6A2', 'IFNAR1', 'PIK3R5', 'ITGAX', 'IGF1R', 'FGF7', 'LPAR6', 'ANGPT1', 'PPP2R5E', 'PELO', 'LPAR4', 'CREB5', 'OSMR', 'PDGFC', 'ITGA9', 'EFNA3', 'CREB3L4', 'ITGA11', 'CSH1', 'CHAD', 'CAB39', 'EIF4E2', 'ITGA7', 'COL4A2', 'COL2A1', 'EGF', 'FGF2', 'ITGAV', 'KDR', 'HIF3A', 'PFKFB2', 'TNN', 'TEK', 'PGF', 'CSF3R', 'RAB14', 'ATF4', 'KRAS', 'PIK3C2B', 'COL5A1', 'EPO', 'FGF13', 'PDGFRA', 'PRLR', 'THBS4', 'GHR', 'LAMA4', 'PPP2R5D', 'PDGFRB', 'FGF1', 'TNR', 'ITGA4', 'FGF12', 'PFKFB4', 'SPP1', 'STK11', 'PDGFB', 'PIK3IP1', 'OSM', 'EFNA2', 'PPP2R3C', 'ANGPT2', 'NOS1', 'RAB10', 'FLT1', 'FGF9', 'CAB39L', 'FGF14', 'LAMA1', 'ANGPT4', 'TCL1A', 'FGF11', 'ITGA5', 'FGFR4', 'SLC2A2', 'FGF19', 'DDIT4', 'RAB8A', 'HSP90B1', 'NOS3', 'ITGA2', 'EFNA1', 'IL7R', 'CHRM1', 'TNXB', 'CREB3L1', 'KIT', 'ITGAD', 'PPP2R2B', 'FGF18', 'PFKFB1', 'CRTC2', 'IL6R', 'IFNAR2', 'FGF17', 'PTEN', 'IFNB1', 'LPAR3', 'PDGFD', 'PFKFB3', 'PTK2', 'EIF4E1B', 'PPP2R2D', 'CSF1R', 'CREB3L2', 'CHRM2', 'GRB2', 'EFNA5', 'COL4A1', 'EPOR', 'FGF3', 'THBS2', 'IL3RA', 'RAB11B', 'LPAR5', 'RELN', 'STRADA', 'ACACA', 'EFNA4', 'IFNA7', 'LAMB3', 'LAMA2', 'FGF16', 'ATF6B', 'TCL1B', 'AKT1S1', 'COL5A2', 'COL11A2', 'LPAR1', 'COL4A6', 'PDGFA'], 'Transcriptional cascade regulating adipogenesis': ['KLF2', 'DDIT3', 'KLF15', 'KLF5', 'CEBPG', 'GATA3', 'CEBPD', 'SREBF1', 'CEBPA', 'GATA2', 'PPARG', 'CEBPB', 'EGR2'], 'White fat cell differentiation (WP4149)': ['KLF2', 'MECOM', 'EBF1', 'KLF15', 'KLF5', 'DDIT3', 'TCF7L1', 'INS', 'FOXO1', 'WNT10B', 'IRF3', 'TLE3', 'KLF4', 'CREB1', 'NR3C1', 'GATA3', 'CEBPD', 'CEBPA', 'SREBF1', 'CTNNA1', 'NR1H3', 'GATA2', 'RARA', 'PPARG', 'STAT5B', 'CEBPB', 'STAT5A', 'EGR2', 'RORA', 'NR2F2', 'ZNF423', 'IRF4'], 'mBDNF and proBDNF regulation of GABA neurotransmission': ['SHC1', 'PIK3R1', 'CREB1', 'PIK3CA', 'PIK3R3', 'GABRA1', 'PIK3CB', 'RHOA', 'JAK2', 'PIK3R2', 'PIK3CG', 'STAT3', 'BDNF', 'GABRG2', 'ROCK1', 'GABRG1', 'AP2A1', 'AP2A2', 'CREM', 'GABRP', 'GABRE', 'AP2B1', 'PTEN', 'PLCG1', 'NTRK2', 'NGFR', 'GABRD', 'GABRG3', 'GABRQ', 'GABRA5', 'GABRB3', 'SLC12A5', 'GABRA3', 'GABRA6', 'GABRA4', 'GABRA2', 'GABRB2', 'GABRB1'], 'Neuroinflammation': ['MTOR', 'CHUK', 'JUN', 'FOS', 'TLR4', 'NFKBIA', 'MAPK14', 'MAPK8', 'NOS2', 'MT-CO2', 'MT-CO1', 'RELA', 'ASCC1'], 'Liver X receptor pathway': ['ABCG8', 'ABCG5', 'SCD', 'RXRA', 'SREBF1', 'CYP3A4', 'CYP7A1', 'CYP2B6', 'NR1H3', 'FASN'], 'Adipogenesis': ['ADIPOQ', 'FOXC2', 'LMNA', 'GATA2', 'SFRP4', 'RARA', 'CDKN1A', 'CEBPA', 'ZMPSTE24', 'CEBPD', 'IL6', 'IRS1', 'INS', 'LPL', 'LEP', 'MEF2B', 'MEF2A', 'MEF2D', 'MEF2C', 'PCK1', 'AHR', 'EPAS1', 'FOXO1', 'GATA3', 'WWTR1', 'NR3C1', 'IGF1', 'HIF1A', 'FAS', 'CREB1', 'CTNNB1', 'NR1H3', 'PPARGC1A', 'NCOA2', 'BMP2', 'SCD', 'SLC2A4', 'BMP3', 'BMP4', 'RXRA', 'SOCS1', 'NCOA1', 'SOCS3', 'IRS2', 'WNT10B', 'IRS4', 'NRIP1', 'STAT1', 'SREBF1', 'STAT3', 'STAT2', 'TNF', 'TGFB1', 'WNT1', 'SP1', 'CYP26B1', 'PPARD', 'HMGA1', 'MIF', 'STAT6', 'PNPLA3', 'KLF7', 'GADD45A', 'DDIT3', 'GATA4', 'EBF1', 'GDF10', 'BSCL2', 'KLF15', 'MBNL1', 'GTF3A', 'NDN', 'ASIP', 'FRZB', 'PCK2', 'CISD1', 'KLF5', 'SPOCK1', 'MIXL1', 'NR2F1', 'AGPAT2', 'PLIN2', 'CELF1', 'ID3', 'RBL1', 'NAMPT', 'E2F4', 'RXRG', 'RBL2', 'GH1', 'LIF', 'IL6ST', 'LIPE', 'LIFR', 'SMAD3', 'OSM', 'SERPINE1', 'PPARA', 'PLIN1', 'PRLR', 'PPARG', 'CEBPB', 'CNTFR', 'CFD', 'KLF6', 'DVL1', 'AGT', 'E2F1', 'PTGIS', 'TRIB3', 'BMP1', 'RB1', 'STAT5B', 'STAT5A', 'TWIST1', 'HNF1A', 'WNT5B', 'FZD1', 'NCOR2', 'UCP1', 'RORA', 'LPIN3', 'LPIN2', 'RETN', 'GADD45B', 'NCOR1', 'DLK1', 'EGR2', 'CYP26A1', 'LPIN1'], 'IL9 signaling': ['CDK9', 'IL2RG', 'JAK1', 'PIK3R1', 'MAPK3', 'MAPK1', 'PIK3R2', 'MAP2K2', 'MAP2K1', 'STAT3', 'STAT1', 'IL9', 'IL9R', 'GRB2', 'JAK3', 'STAT5B', 'STAT5A'], 'Airway smooth muscle cell contraction': ['RYR1', 'GNAQ', 'IL13', 'RHOA', 'CALM1', 'GDI1', 'ROCK2', 'PPP1R14A', 'ROCK1', 'PLCB1', 'PPP1CB', 'MYL1', 'ADRB2', 'MYLK', 'CD38', 'ITPR3'], 'IL4 signaling': ['ATF2', 'CHUK', 'HRH1', 'CEBPA', 'STAT1', 'STAT3', 'TYK2', 'BAD', 'PTPN6', 'PTPN11', 'SOS1', 'RPS6KB1', 'SHC1', 'PIK3R2', 'PIK3R1', 'NFKBIA', 'PIK3CD', 'PIK3CA', 'MAPK11', 'MAPK1', 'MAPK3', 'JAK1', 'JAK2', 'IRS1', 'NFKB1', 'IKBKB', 'BIRC5', 'IL4R', 'IL2RG', 'IL4', 'EP300', 'ELK1', 'AKT1', 'MAPK14', 'GATA3', 'FOS', 'RELA', 'STAT5B', 'STAT5A', 'JAK3', 'CEBPB', 'GRB2', 'FLNA', 'STAT6', 'IRS2', 'SOCS1', 'CBL', 'SOCS3', 'DOK2', 'GAB2', 'NFIL3', 'INPP5D', 'FES', 'SOCS5'], 'GABA receptor signaling': ['SLC32A1', 'GAD1', 'ABAT', 'GAD2', 'GABRA1', 'SLC6A11', 'GABRG2', 'ALDH9A1', 'GPHN', 'SLC6A1', 'GABBR2', 'AP2B1', 'AP2S1', 'GABRE', 'AP2A1', 'AP2A2', 'GABRP', 'GABRA3', 'GABRG1', 'GABRA4', 'GABRB2', 'AP2M1', 'GABRA2', 'GABRB3', 'GABRG3', 'GABRB1', 'GABRA5', 'GABRQ', 'GABRA6', 'GABBR1', 'GABRD'], 'IL1 signaling': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2'], 'MAPK signaling': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42'], 'Cytokines and inflammatory response': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3'], 'Inflammatory response pathway': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2'], 'Molecular pathway for oxidative stress': [], 'Interleukin-1 induced activation of NF-kB': ['AJUBA', 'SQSTM1', 'TRAF6', 'UBE2N', 'IRAK1', 'UBE2V1', 'NFKB1', 'IL1A', 'PRKCZ', 'TIFA'], 'Oxidative stress response': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH'], 'Growth factors and hormones in beta cell proliferation': ['PDX1', 'MYC', 'INS', 'IGF1', 'INSR', 'FOXO1', 'AKT3', 'CDK4', 'CDK2', 'MAPK3', 'MAPK1', 'AKT1', 'AKT2', 'SMAD7', 'KRAS', 'PDGFA', 'IGF1R', 'BRAF', 'FLT1', 'TGFBR1', 'PGF', 'CRTC2', 'RASSF1', 'DLK1', 'FOXM1', 'RAB43'], 'Microtubule cytoskeleton regulation': ['GSK3B', 'ABL1', 'RHO', 'TAOK1', 'MAPT', 'PRKCA', 'CAMK4', 'GNAQ', 'AKT1', 'PAK1', 'STAT3', 'SRC', 'CDK1', 'PIK3CA', 'RAC1', 'F2RL2', 'CDC42', 'PRKACA', 'TRIO', 'PHLDB2', 'DIAPH1', 'TPPP', 'MAPKAPK2', 'CFL2', 'DPYSL2', 'SPRED1', 'CLASP1', 'TESK2', 'ROCK1', 'PTEN', 'AURKB', 'APC', 'WNT3A', 'TIAM1', 'DVL1', 'PARD6A', 'STMN1', 'PTPRA', 'CLIP1', 'EPHB2', 'MAPRE1', 'MAP1B', 'KIF2C', 'LIMK1', 'MARK2', 'MARK1'], 'Axon guidance': [], 'Disruption of postsynaptic signaling by CNV': ['GRM1', 'ARC', 'MAPK1', 'MAPK3', 'NRXN1', 'NRXN2', 'NRXN3', 'DLG2', 'SHANK1', 'GRIN2D', 'GRIN2C', 'YWHAG', 'CAMK2G', 'RPH3A', 'SYNGAP1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'NLGN1', 'HOMER1', 'CYFIP1', 'NLGN2', 'NLGN3', 'NLGN4X', 'DLG1', 'RYR2', 'DLGAP1', 'CAMK2B', 'STX1A', 'TJP1', 'FMR1', 'CAMK2A', 'CAMK2D'], 'Brain-derived neurotrophic factor (BDNF) signaling': ['CREB1', 'CHUK', 'MAPK14', 'CTNNB1', 'CSNK2A1', 'VAV3', 'BCL2L11', 'MAP3K2', 'EIF4EBP1', 'MTOR', 'MAPT', 'ALPL', 'NFATC4', 'PTPRF', 'NTF3', 'GRIP1', 'PTK2B', 'DLG1', 'PRKAA2', 'PIK3R1', 'SHC3', 'PIK3R2', 'PRKAA1', 'PPP2CA', 'MAP3K1', 'NCAM1', 'JAK2', 'JUN', 'MEF2C', 'MEF2A', 'PDPK1', 'NCF2', 'NFKB1', 'NGF', 'NFKBIA', 'AKT1', 'FOXO3', 'FOS', 'EIF4E', 'ELK1', 'IKBKB', 'IRS1', 'SHC2', 'GSK3B', 'HRAS', 'FRS2', 'CFL1', 'VAV2', 'CAMK2A', 'CAMK4', 'SYN1', 'STAT3', 'TSC2', 'TRAF6', 'IRS2', 'SQSTM1', 'RPS6KA5', 'IKBKG', 'CASP3', 'RPS6', 'RPS6KA1', 'RPS6KA3', 'BDNF', 'RPS6KB1', 'RAF1', 'NCF1', 'SRC', 'STAT1', 'BMP2', 'SHC1', 'BAD', 'MAPK10', 'MAPK9', 'MAP2K1', 'MAP2K2', 'MAP2K5', 'PTPN11', 'RAB3A', 'RAC1', 'MAPK8', 'MAPK1', 'MAPK7', 'MAPK3', 'DOK5', 'PRKCD', 'NSF', 'CDK5R1', 'NCK2', 'MARCKS', 'EIF2S2', 'DOCK3', 'DPYSL2', 'SH2B1', 'CDKL5', 'RANBP9', 'GRIA3', 'GRIA2', 'YBX1', 'CDH2', 'CDK5', 'EGR1', 'SIRPA', 'EIF2S1', 'EEF2', 'CNR1', 'EGR2', 'NTRK3', 'RACK1', 'FRS3', 'LINGO1', 'KCNA3', 'CDC42', 'CRTC1', 'IGF2BP1', 'RHOG', 'CAMK1', 'KSR1', 'SH2B2', 'GABRB3', 'CYFIP1', 'ACACB', 'KCNN2', 'SPP1', 'KIDINS220', 'RASGRF1', 'RAP1A', 'RELA', 'SORT1', 'STAT5B', 'ADAM17', 'TIAM1', 'STAT5A', 'APC', 'SHC4', 'FYN', 'GRIA1', 'GRB2', 'GRIN2B', 'GRIN1', 'NGFR', 'NCK1', 'NTRK1', 'PLCG1', 'NTRK2'], 'TGF-beta receptor signaling': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A'], 'Cells and molecules involved in local acute inflammatory response': ['SELPLG', 'TNF', 'IL6', 'ITGB1', 'CXCL8', 'ITGB2', 'IL1A', 'VCAM1', 'ICAM1', 'C3', 'SELP', 'C5', 'C7', 'C6', 'ITGA4', 'ITGAL', 'KNG1'], 'Chemokine signaling': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2'], 'DNA repair pathways full network': ['FAAP24', 'RFC3', 'PCNA', 'RPA1', 'FANCD2', 'FANCI', 'BRCA2', 'BRIP1', 'CHEK1', 'ATM', 'POLE3', 'WRN', 'RFC4', 'USP1', 'FANCC', 'ATR', 'EXO1', 'POLH', 'CENPX', 'FANCM', 'FANCA', 'FAAP100', 'FANCF', 'FANCB', 'POLE', 'ERCC4', 'POLD4', 'CENPS', 'FANCG', 'FAN1', 'HMGB1', 'H2AX', 'APEX1', 'RBX1', 'XRCC5', 'MLH1', 'PMS2', 'PARP2', 'XPC', 'XRCC4', 'LIG4', 'GTF2H5', 'MNAT1', 'POLB', 'GTF2H3', 'GTF2H1', 'ERCC2', 'RAD23B', 'RAP1A', 'CDK7', 'DDB2', 'CCNH', 'GTF2H2', 'PARP1', 'ERCC3', 'GTF2H4', 'RAD23A', 'LIG3', 'REV3L', 'PNKP', 'ERCC8', 'NTHL1', 'XRCC1', 'UNG', 'MSH2', 'POLI', 'MPG', 'LIG1', 'NEIL3', 'MSH3', 'OGG1', 'MSH6', 'POLM', 'SMUG1', 'MBD4', 'TERF2', 'MUTYH', 'ERCC5', 'REV1', 'XPA', 'TDG', 'CUL4A', 'CETN2', 'DCLRE1C', 'NEIL2', 'CUL4B', 'POLL', 'DDB1', 'FEN1', 'APEX2', 'MGMT', 'NHEJ1', 'XRCC6', 'RAD54B', 'ERCC6', 'PRKDC', 'RAD52', 'BRCA1', 'ERCC1', 'MRE11', 'RFC1', 'RFC2', 'RAD51', 'POLD1', 'POLD3', 'PALB2', 'POLE2', 'NBN', 'RPA3', 'POLD2', 'RAD51C', 'RFC5', 'FANCE', 'RAD50', 'WDR48', 'POLE4', 'FANCL', 'RPA2', 'POLK'], 'Type II interferon signaling': ['PSMB9', 'ISG15', 'CXCL10', 'NOS2', 'IFNGR1', 'IFNGR2', 'IFI6', 'ICAM1', 'CXCL9', 'PRKCD', 'IFNB1', 'HLA-B', 'CIITA', 'OAS1', 'IFNA2', 'IRF1', 'TAP1', 'REG1A', 'IRF4', 'IRF8', 'IRF2', 'SOCS3', 'STAT1', 'STAT2', 'H4C1', 'SOCS1', 'IFIT2', 'IRF9', 'PTPN11', 'CYBB', 'IL1B', 'IFNG', 'JAK2', 'JAK1', 'SPI1', 'GBP1', 'EIF2AK2'], 'Interferon-mediated signaling': ['IFNAR1', 'IFNAR2', 'IFNA7', 'IFNGR2', 'IFNB1', 'IFNGR1', 'IFNE', 'IFNA14', 'IFNA10', 'IFNA13', 'IFNA1', 'IFNA2', 'IFNA6', 'IFNA8', 'IFNA4', 'IFNA5', 'IFNA21', 'IFNA16', 'IFNA17', 'IFNK', 'IFNW1', 'PRKCA', 'PIK3R1', 'PIK3CA', 'IFNL2', 'IFNL1', 'IFNL3', 'IFNG', 'JAK1', 'IL10RB', 'JAK2', 'IRF9', 'IFNLR1', 'IFNL4', 'TYK2', 'STAT1', 'STAT2'], 'Apoptosis modulation and signaling': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53'], 'Metabolic pathways of fibroblasts': ['ALDH18A1', 'UGDH', 'GCK', 'CD36', 'PYCR1', 'PSPH', 'RHOA', 'GLUD1', 'SLC2A1', 'GPI', 'GLS', 'LDHA', 'SLC1A5', 'PSAT1', 'LOXL2', 'UGP2', 'P3H3', 'SLC16A1', 'P4HA3', 'P3H4', 'PHGDH', 'PGM1', 'BMP1', 'P4HA1', 'ADAMTS2', 'FGFR1', 'SERPINH1', 'PLOD1', 'PLCG1', 'FGFR4', 'LPAR1', 'P4HA2'], 'TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition': ['AKT1', 'VIM', 'CDH1', 'MAPK3', 'TNC', 'SMAD2', 'SMAD3', 'ID1', 'CDH2', 'SNAI2', 'CDH16', 'CDH6', 'MAPK1', 'SNAI1', 'SMAD4', 'RUNX2', 'FN1'], 'Angiotensin II receptor type 1 pathway': ['ACTA2', 'COL1A1', 'MAP2K6', 'MAPK1', 'HIF1A', 'TGFB1', 'PTPN11', 'SP1', 'COL1A2', 'JUND', 'RAF1', 'SMAD4', 'IL11', 'TGFBR2', 'CCN2', 'TGFBR1', 'RRAS', 'F12', 'IL11RA', 'IL6ST', 'AGTR1', 'NOX4', 'RACK1', 'AGT', 'MAS1', 'ACE2', 'PDGFD', 'SMAD3'], 'SARS-CoV-2 replication organelle formation': ['PIK3R4', 'AMBRA1', 'BECN1', 'PIK3C3', 'ZFYVE1', 'ATG14'], 'Toll-like receptor signaling related to MyD88': ['TICAM1', 'TLR2', 'TRAF3', 'TLR4', 'IRF3', 'IKBKB', 'MAPK1', 'NFKB1', 'TOLLIP', 'TIRAP', 'TLR9', 'TICAM2', 'IKBKE', 'IKBKG', 'CHUK', 'TRAF6', 'TBK1', 'TLR6', 'TLR1', 'TLR7', 'IRAK4', 'IRF7', 'IRAK1', 'MYD88', 'TLR8', 'NFKB2', 'TLR3', 'TLR5', 'REL', 'RELB', 'RELA'], 'Wnt signaling': ['SERPINF1', 'MAP3K7', 'CAMK2D', 'PPP3CA', 'SOST', 'PRKCB', 'CSNK2B', 'CTNNB1', 'GSK3B', 'WNT5A', 'CCND1', 'RAC1', 'PRKCA', 'WNT16', 'MYC', 'LRP5', 'RHOA', 'JUN', 'WNT1', 'NFATC3', 'CCND2', 'AXIN1', 'WNT10B', 'PLCB4', 'TCF7', 'CSNK1A1', 'PLCB2', 'ROCK2', 'TCF7L1', 'PLCB3', 'TCF7L2', 'CAMK2G', 'LEF1', 'FZD10', 'CCND3', 'DAAM1', 'NFATC2', 'CTBP1', 'CTBP2', 'PLCB1', 'WNT2', 'PRKCG', 'WNT4', 'PLAU', 'LRP6', 'APC', 'FZD2', 'DVL3', 'DVL2', 'DVL1', 'WNT5B', 'WNT10A', 'FZD3', 'FZD5', 'WNT2B', 'WNT11', 'WNT7B', 'WNT7A', 'WNT6', 'WNT3', 'WNT3A', 'FZD9', 'FZD8', 'FZD7', 'FZD6', 'FZD1', 'GPC4', 'NLK', 'CHD8', 'NFATC4', 'PORCN', 'SFRP1', 'DKK4', 'SFRP4', 'PPP3CB', 'INVS', 'SFRP5', 'PPP3CC', 'PRICKLE1', 'NKD1', 'SFRP2', 'NKD2', 'DAAM2', 'CER1', 'DKK2', 'WIF1', 'VANGL2', 'PRICKLE2', 'SENP2', 'SOX17', 'CXXC4', 'VANGL1', 'CTNNBIP1', 'FRAT2', 'NOTUM', 'PPP3R2', 'PPP3R1', 'CSNK2A3', 'FRAT1', 'CSNK1E', 'ROR1', 'ROR2', 'RYK', 'FOSL1', 'KREMEN1', 'MAPK9', 'CAMK2B', 'CSNK2A2', 'CAMK2A', 'CSNK2A1', 'MAPK8', 'DKK1', 'NFATC1'], 'Pregnane X receptor pathway': ['UGT1A9', 'ABCC2', 'CYP4F12', 'NCOA3', 'PPARGC1A', 'HSP90AA1', 'NCOA1', 'CYP2B6', 'RXRA', 'SRC', 'NRIP1', 'FOXO1', 'CYP3A4', 'NCOA2', 'UGT1A4', 'CYP2A6', 'ABCC4', 'SLCO1B1', 'ABCC3', 'PSMC5', 'ABCB1', 'CYP2C9', 'GSTA2', 'UGT1A1', 'UGT1A6', 'DNAJC7', 'CYP3A7', 'SRPX2', 'CYP3A5', 'CYP2C19', 'NR1I2', 'SULT2A1'], 'TNF-alpha signaling': ['RFK', 'NFKBIE', 'NFKBIB', 'NSMAF', 'PTPRCAP', 'CHUK', 'RIPK3', 'TAB1', 'TRAP1', 'TANK', 'AKT1', 'CYBA', 'CSNK2A1', 'CREBBP', 'MAP3K8', 'RFFL', 'TBK1', 'TAB3', 'TAB2', 'IKBKB', 'HSP90AA1', 'BIRC3', 'BIRC2', 'HRAS', 'APAF1', 'IL6', 'MAP3K3', 'JUN', 'MAP3K1', 'NRAS', 'NFKBIA', 'NFKB1', 'MAP3K5', 'MAPK8', 'MAPK3', 'MAPK1', 'PPP2CA', 'BAD', 'DIABLO', 'MAP2K7', 'MAP2K6', 'MAP2K3', 'MAPK9', 'BCL2L1', 'RAF1', 'RAC1', 'MAP4K2', 'BAX', 'SOS1', 'MAP2K4', 'BID', 'CCL2', 'TNF', 'MAP3K7', 'TRADD', 'MADD', 'IKBKG', 'CASP9', 'CASP8', 'CASP7', 'CASP3', 'TNFRSF1B', 'TNFRSF1A', 'CFLAR', 'MAP3K14', 'FADD', 'RIPK1', 'NOXO1', 'GLUL', 'SMPD2', 'CDC37', 'GRB2', 'KSR2', 'PLK1', 'NFKB2', 'KRAS', 'SKP1', 'REL', 'PSMD2', 'OTUD7B', 'PRKCZ', 'CUL1', 'TXN', 'TRAF2', 'TRAF1', 'TNFAIP3', 'BTRC', 'KSR1', 'FBXW11', 'NOX1', 'SELE', 'PYGL'], 'Complement activation': ['C4A', 'C1QC', 'C1QA', 'C1QB', 'CFP', 'C1R', 'MASP2', 'CD55', 'CFD', 'MASP1', 'CFB', 'C1S', 'C2', 'C3', 'C7', 'C8A', 'C8G', 'C9', 'C4B', 'C5', 'C6', 'C8B'], 'PI3K-Akt signaling': ['NFKB1', 'COL1A1', 'VTN', 'COMP', 'PIK3CG', 'FGF8', 'RPS6KB1', 'ITGB8', 'RHEB', 'PPP2CA', 'VEGFA', 'IL4', 'CCND1', 'CDKN1B', 'IL2', 'COL9A1', 'GNB3', 'PKN1', 'CD19', 'BAD', 'CDKN1A', 'BRCA1', 'IGF1', 'COL9A2', 'GNB5', 'IL4R', 'PIK3CB', 'LAMC2', 'HSP90AA1', 'GSK3B', 'PPP2R5C', 'GNB1', 'EIF4EBP1', 'MTOR', 'SGK3', 'SGK2', 'NTF3', 'NTF4', 'LAMB1', 'ITGA6', 'ITGB5', 'JAK2', 'MAPK1', 'COL9A3', 'HSP90AB1', 'IL2RB', 'SOS2', 'TSC2', 'IKBKB', 'MAPK3', 'CCNE1', 'AKT2', 'PPP2CB', 'GYS1', 'PPP2R1A', 'PIK3R2', 'BDNF', 'F2R', 'RPS6KB2', 'GNG7', 'CSF1', 'GNG12', 'GNG5', 'HRAS', 'VEGFB', 'IKBKG', 'PIK3R6', 'GNG2', 'NRAS', 'INS', 'ITGB3', 'CHUK', 'GNG10', 'TGFA', 'IL3', 'VEGFD', 'TSC1', 'COL1A2', 'SYK', 'MLST8', 'GNG4', 'GNGT2', 'GNG8', 'IRS1', 'THBS3', 'MAP2K1', 'PIK3CD', 'BCL2', 'INSR', 'BCL2L1', 'GNB2', 'LAMB2', 'PRL', 'TP53', 'RPTOR', 'ITGB7', 'PDPK1', 'MCL1', 'PIK3R1', 'AKT1', 'EGFR', 'IL2RG', 'ITGB1', 'EIF4E', 'VEGFC', 'GNG3', 'PRKAA2', 'BCL2L11', 'PRKCA', 'JAK1', 'GNGT1', 'LAMA5', 'PRKAA1', 'ITGB4', 'G6PC1', 'RAF1', 'IL2RA', 'CDK4', 'CASP9', 'NGF', 'LAMC1', 'RAC1', 'MDM2', 'MYC', 'RPS6', 'IL6', 'TLR4', 'THBS1', 'TLR2', 'PPP2R1B', 'CREB1', 'MYB', 'FN1', 'SOS1', 'GNB4', 'ITGB6', 'PIK3R3', 'FASLG', 'ATF2', 'AKT3', 'SGK1', 'GNG11', 'CCND2', 'PIK3CA', 'FOXO3', 'MAP2K2', 'GNG13', 'CDK2', 'PCK1', 'THBS4', 'PRLR', 'VWF', 'FGF6', 'CREB3', 'CSF3', 'LAMA4', 'GHR', 'GYS2', 'PPP2R5D', 'FGF1', 'CSF3R', 'ITGA4', 'PDGFRB', 'FGF12', 'SPP1', 'FGF23', 'TNR', 'STK11', 'PDGFB', 'TCL1A', 'EFNA2', 'OSM', 'COL4A4', 'PHLPP1', 'PPP2R3C', 'FLT3LG', 'ANGPT2', 'MET', 'FGF21', 'JAK3', 'LAMA1', 'FGF14', 'ANGPT4', 'IL7', 'CDC37', 'FGF9', 'FLT1', 'NGFR', 'LPAR2', 'CREB3L3', 'EIF4B', 'PPP2R5A', 'FGFR2', 'LAMC3', 'LAMA3', 'TNC', 'KITLG', 'FGFR1', 'ITGA8', 'PPP2R2C', 'FGF4', 'FGF20', 'FGFR3', 'FGF22', 'PPP2R3A', 'PPP2R5B', 'FGF10', 'ITGA3', 'ITGA2B', 'FLT4', 'PHLPP2', 'HGF', 'IBSP', 'PCK2', 'CCND3', 'CCNE2', 'CDK6', 'PPP2R2A', 'RELA', 'ATF6B', 'NTRK1', 'TCL1B', 'RELN', 'LAMA2', 'COL4A1', 'COL4A6', 'LPAR1', 'LAMB3', 'PDGFA', 'EFNA4', 'GH1', 'ITGA1', 'IFNA7', 'PTEN', 'PPP2R2D', 'LPAR3', 'IFNB1', 'EIF4E1B', 'CHRM1', 'PTK2', 'PDGFD', 'IL7R', 'EFNA1', 'FGF3', 'EPOR', 'IL3RA', 'THBS2', 'GRB2', 'CHRM2', 'EFNA5', 'LPAR5', 'CREB3L2', 'CSF1R', 'KIT', 'CREB3L1', 'FGF18', 'PPP2R2B', 'THEM4', 'FGF17', 'IFNAR2', 'PPP2R5E', 'ANGPT1', 'NTRK2', 'NOS3', 'HSP90B1', 'FGF19', 'ITGA2', 'DDIT4', 'TNXB', 'ITGA5', 'FGF11', 'IL6R', 'FGFR4', 'COL2A1', 'LPAR6', 'FGF2', 'EGF', 'PIK3R5', 'COL6A1', 'FGF7', 'IGF1R', 'IFNAR1', 'COL6A2', 'EPHA2', 'EFNA3', 'ITGA10', 'CREB3L4', 'OSMR', 'CREB5', 'ITGA9', 'PDGFC', 'LPAR4', 'PGF', 'TEK', 'FLT3', 'KDR', 'TNN', 'EPO', 'ATF4', 'FGF13', 'PDGFRA', 'COL4A2', 'KRAS', 'CHAD', 'CSH1', 'ITGA7', 'EIF4E2', 'FGF5', 'ITGA11', 'ITGAV', 'COL4A3', 'COL4A5', 'CSH2', 'PIK3AP1', 'PKN3', 'G6PC3', 'G6PC2', 'PKN2', 'LAMB4', 'IFNA21', 'IFNA5', 'IFNA6', 'IFNA8', 'IFNA16', 'PPP2R3B', 'IFNA17', 'IFNA4', 'IFNA14', 'IFNA13', 'IFNA2', 'IFNA1', 'IFNA10', 'RBL2', 'GH2', 'IGF2', 'COL6A6', 'COL6A3', 'COL6A5'], 'Phosphatidyl inositol phosphate pathway': ['MTMR6', 'MTMR8', 'PI4K2A', 'PI4K2B', 'TPTE2', 'INPP4B', 'PLCB4', 'PLCB3', 'PLCB2', 'PI4KB', 'PIP5K1C', 'INPP5E', 'PLCD4', 'PIK3C2A', 'PIK3CD', 'PIK3CG', 'PIK3CB', 'PIK3CA', 'PLCG2', 'PIK3C2G', 'INPP4A', 'PI4KA', 'PLCD3', 'PLCD1', 'PIKFYVE', 'SACM1L', 'PIP5K1A', 'INPP5D', 'FIG4', 'PIP4K2C', 'MTMR1', 'MTM1', 'OCRL', 'PIP4K2B', 'PIP4K2A', 'PIP5K1B', 'PIP4P2', 'PIP4P1', 'MTMR2', 'PLCE1', 'PLCB1', 'PIK3C2B', 'INPP5K', 'PTEN', 'PLCG1', 'IPMK'], 'GPCRs class C metabotropic glutamate pheromone': ['GRM3', 'GPRC5B', 'GPRC5C', 'GPRC5A', 'GRM1', 'GRM2', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GABBR2', 'GRM6', 'CASR', 'GPRC5D', 'GABBR1'], 'p53 transcriptional gene network': ['PRKAB2', 'PRKAA1', 'PCNA', 'GLS2', 'CDK2', 'POLK', 'CCNG1', 'PRKAB1', 'NCF2', 'PRKAG3', 'FASLG', 'SLC2A1', 'TNFRSF10B', 'APAF1', 'CCL2', 'TSC2', 'CCNE1', 'BBC3', 'BAX', 'PRKAG2', 'ULBP1', 'CDKN1A', 'FAS', 'TIGAR', 'MTOR', 'MSH2', 'CX3CL1', 'ERCC5', 'PML', 'MGMT', 'ACAD11', 'PRKAA2', 'MLST8', 'POLH', 'ADORA2B', 'TNFRSF10D', 'FANCC', 'THBS1', 'PMAIP1', 'RPTOR', 'NOTCH1', 'SERPINE1', 'AURKA', 'LIF', 'MIR34B', 'MIR34C', 'MIR34A', 'GADD45A', 'TP53I3', 'XPC', 'SLC7A11', 'BTG2', 'CDC25C', 'TP53AIP1', 'ULBP2', 'SAT1', 'MLH1', 'ICAM1', 'XRCC5', 'ULK1', 'PRKAG1', 'PIDD1', 'IRF9', 'MIR145', 'TNF', 'GPX1', 'AKT1S1', 'DDB2', 'DEPTOR', 'PTEN', 'DDIT4', 'ISG15', 'RRM2B', 'SESN1', 'CDC25A', 'ULK2', 'IRF5', 'NANOG', 'MIR200C', 'SESN2', 'SCO2', 'SFN', 'FUCA1', 'SIVA1', 'ADGRB1', 'SERPINB5', 'PERP', 'TRAF4', 'ALDH4A1', 'DRAM1', 'E2F7', 'TP53INP1', 'SMR3B', 'CPT1C', 'RPRM', 'ZMAT3'], 'Bile acid synthesis and enterohepatic circulation': ['LDLR', 'CYP7A1', 'ABCG8', 'ABCG5', 'MAPK3', 'MAPK1', 'FXR1', 'SLC10A2', 'FGFR4', 'SLC10A1', 'FGF19', 'ABCB11'], 'Renin-angiotensin-aldosterone system (RAAS': ['CAMK1G', 'CAMK1D', 'CREB3', 'CAMK1', 'CREB3L1', 'AGTR2', 'AGTR1', 'AGT', 'CMA1', 'CREB3L3', 'CREB3L2', 'CREB5', 'CREB3L4', 'ITPR2', 'ITPR1', 'CALML6', 'CALML5', 'CALML4', 'CALML3', 'CALM2', 'ATF6B', 'ATF4', 'STAR', 'ITPR3', 'CYP21A2', 'CYP11A1', 'ACE', 'HSD3B1', 'HSD3B2', 'CYP11B2', 'CAMK2A', 'CALM1', 'CAMK2B', 'CAMK4', 'CAMK2D', 'CREB1', 'GNAQ', 'CALM3', 'ATF2', 'REN', 'CAMK2G', 'ATF1', 'PLCB2', 'CTSG'], 'Autophagy': ['MTOR', 'RPTOR', 'PRKAA1', 'PRKAB2', 'MAP1LC3B', 'PRKAA2', 'MLST8', 'ATG3', 'ATG12', 'AMBRA1', 'PRKAB1', 'PRKAG3', 'ATG101', 'BECN1', 'PIK3C3', 'RB1CC1', 'ATG5', 'PRKAG2', 'ATG16L1', 'PRKAG1', 'ATG13', 'ULK1', 'PIK3R4', 'ATG7', 'ATG14', 'WIPI2', 'AKT1S1', 'DEPTOR', 'ATG9A', 'UVRAG'], 'Ras signaling': ['BAD', 'MAPK9', 'PIK3CB', 'GNGT1', 'RAC2', 'SHC2', 'PAK4', 'ELK1', 'MAP2K2', 'GNG13', 'GNG11', 'PAK6', 'RAF1', 'RAC1', 'GNB4', 'ZAP70', 'GNB3', 'FASLG', 'PIK3CA', 'SOS1', 'AKT3', 'PIK3R3', 'PAK5', 'MAPK3', 'IKBKB', 'AKT2', 'MAPK1', 'SOS2', 'MAPK8', 'NFKB1', 'MAPK10', 'PIK3R2', 'GNB5', 'PAK3', 'GNB1', 'ABL1', 'RHOA', 'GNGT2', 'GNG8', 'GNG4', 'MAP2K1', 'PRKCB', 'SHC3', 'HTR7', 'AKT1', 'PIK3R1', 'RASA1', 'EGFR', 'PAK1', 'PRKCA', 'SHC1', 'GNG3', 'GNG10', 'CHUK', 'IKBKG', 'HRAS', 'GNG7', 'PTPN11', 'PAK2', 'GNG5', 'GNG2', 'PLCG2', 'CALM1', 'NRAS', 'LAT', 'RAC3', 'INSR', 'BCL2L1', 'PIK3CD', 'GNB2', 'GNG12', 'PLA2G4A', 'PLA2G2D', 'EXOC2', 'RASGRF2', 'PDGFRB', 'RAP1A', 'RASAL3', 'PLA2G4C', 'RASA4', 'FLT1', 'RASAL1', 'RAB5B', 'SHOC2', 'RAB5C', 'GAB1', 'PLD1', 'FGFR1', 'CDC42', 'PRKACA', 'RASAL2', 'PLA2G3', 'STK4', 'BRAP', 'RALA', 'RALBP1', 'GAB2', 'FLT4', 'FGFR2', 'RASSF1', 'FGFR3', 'RASGRP2', 'PLA2G10', 'RASGRF1', 'NGFR', 'AFDN', 'ABL2', 'RGL1', 'CALM2', 'RALB', 'RAB5A', 'EPHA2', 'PRKACB', 'RASA2', 'TIAM1', 'KIT', 'PLA1A', 'TTBK1', 'NTRK2', 'RASGRP3', 'RRAS2', 'PDGFRA', 'ETS1', 'RAPGEF5', 'PLD2', 'KRAS', 'IGF1R', 'KSR1', 'PLCE1', 'PLA2G12B', 'PLCG1', 'TEK', 'FLT3', 'PLA2G12A', 'RRAS', 'PRKCG', 'RAP1B', 'PLA2G5', 'KDR', 'CALML4', 'RASGRP1', 'CALML6', 'PLA2G1B', 'KSR2', 'RASGRP4', 'PLAAT3', 'GRIN1', 'GRB2', 'CALML3', 'CALML5', 'RIN1', 'FGFR4', 'ETS2', 'MRAS', 'PLA2G2F', 'PLA2G4D', 'CALM3', 'RALGDS', 'JMJD7-PLA2G4B', 'PRKACG', 'ARF6', 'PLA2G4F', 'MET', 'RGL2', 'PLA2G4B', 'RASSF5', 'GRIN2B', 'NTRK1', 'SHC4', 'RASA3', 'CSF1R', 'GRIN2A', 'PLA2G6', 'FOXO4', 'PLA2G2C', 'PLA2G4E', 'PLA2G2A', 'PLA2G2E', 'SYNGAP1', 'NF1', 'RELA', 'REL'], 'Fatty acid and lipoprotein transport in hepatocytes': ['DBI', 'APOE', 'SOAT1', 'LDLR', 'PCSK9', 'VDAC1', 'ACSL1', 'NPC2', 'SCARB1', 'SLC27A2', 'SORT1', 'APOB', 'ACSL5', 'ACSL6', 'STAR', 'OSBPL5', 'LPA', 'FABP3', 'LDLRAP1', 'SLC27A4', 'LIPA', 'SLC27A1', 'APOA4', 'ACSL3', 'ABCA1', 'MYLIP', 'SLC27A3', 'FABP2', 'APOC1', 'FABP4', 'FABP1', 'LRP1', 'SOAT2', 'STARD3', 'APOC2'], 'Fatty acid beta-oxidation': ['CPT1B', 'HADHA', 'ACADS', 'ACADVL', 'ACSL4', 'CRAT', 'LPL', 'ACAT1', 'HADH', 'GCDH', 'ECHS1', 'ACSL1', 'DLD', 'DECR1', 'ECI1', 'ACADL', 'ACSL3', 'CHKB', 'GPD2', 'ACSS2', 'GK2', 'GK', 'SLC25A20', 'TPI1', 'LIPF', 'CPT2', 'ACSL6', 'ACSL5', 'CPT1A', 'PNPLA2', 'LIPE', 'HADHB', 'ACADM', 'LIPC'], 'Fatty acid biosynthesis': ['ACSL4', 'PECR', 'PC', 'MECR', 'HADH', 'ACSL1', 'FASN', 'ACLY', 'ECHS1', 'ACSS2', 'ACAA2', 'DECR1', 'ACSL3', 'SCD', 'ACACA', 'ECHDC3', 'ECHDC2', 'ACSL5', 'ECHDC1', 'ECH1', 'ACACB', 'ACSL6'], 'Lipid metabolism pathway': ['PRKAB1', 'AKT2', 'PRKAG2', 'PRKAR2A', 'PRKAR1A', 'PRKAR2B', 'ACSBG1', 'ABHD5', 'PRKAR1B', 'HILPDA', 'PRKAG3', 'AKT3', 'ACLY', 'PRKAB2', 'PRKAA1', 'PDHA1', 'PRKAA2', 'AKT1', 'FASN', 'PRKAG1', 'ACSS2', 'BCKDHA', 'PRKACA', 'PRKACG', 'PLIN1', 'LIPE', 'PRKACB', 'PNPLA2', 'ACACA'], 'Regucalcin in proximal tubule epithelial kidney cells': ['TRPV5', 'MTOR', 'CASP9', 'SMAD4', 'RAF1', 'PTH', 'AKT1', 'ACTA2', 'PIK3CA', 'APAF1', 'TNFSF11', 'CASP8', 'TNFRSF1A', 'BAK1', 'TGFB1', 'BAX', 'MAPK1', 'G3BP1', 'PPP3R1', 'SEC16B', 'MAP3K5', 'CALCA', 'CASP3', 'BRAF', 'TGFBR1', 'FFAR3', 'MCU', 'NOS1', 'SMAD2', 'PDE1B', 'RGN'], 'Wnt signaling in kidney disease': ['INVS', 'WNT1', 'WNT5A', 'MAPK10', 'MAPK8', 'WNT16', 'MAPK9', 'RHOA', 'LRP5', 'CTNNB1', 'WNT10B', 'FZD4', 'FZD8', 'FZD5', 'FZD6', 'FZD1', 'FZD7', 'WNT9B', 'WNT4', 'DVL3', 'WNT7A', 'WNT3A', 'WNT10A', 'WNT2B', 'DVL1', 'WNT2', 'WNT3', 'WNT5B', 'WNT6', 'FZD3', 'LRP6', 'WNT11', 'DVL2', 'FZD2', 'FZD9', 'WNT7B'], 'Non-small cell lung cancer': ['CASP8', 'BAK1', 'PIK3CB', 'MAPK3', 'MAPK1', 'BAX', 'SOS2', 'RARB', 'CRABP1', 'CDKN1A', 'BID', 'BAD', 'CRABP2', 'PRKCA', 'TGFA', 'CASP3', 'PRKCB', 'STAT3', 'MAP2K1', 'CDK4', 'MAP2K2', 'RAF1', 'CASP9', 'TP53', 'AKT1', 'PIK3R1', 'CDKN2A', 'EGFR', 'CCND1', 'SOS1', 'AKT2', 'PIK3R2', 'POLK', 'PIK3R3', 'AKT3', 'FOXO3', 'PIK3CA', 'HRAS', 'CYCS', 'RXRA', 'PIK3CD', 'PLCG2', 'NRAS', 'GADD45A', 'E2F2', 'CDK6', 'E2F3', 'FHIT', 'EML4', 'RASSF5', 'GRB2', 'PDK1', 'STAT5B', 'BRAF', 'JAK3', 'E2F1', 'PLCG1', 'PRKCG', 'STAT5A', 'DDB2', 'RB1', 'EGF', 'ERBB2', 'KRAS', 'RASSF1', 'ARAF', 'STK4', 'RXRB', 'GADD45B', 'ALK', 'GADD45G', 'RXRG'], 'Neurotransmitter disorders': ['TPH1', 'DDC', 'TH', 'MAOA', 'SLC18A2', 'SLC6A3', 'TPH2', 'COMT', 'PNMT', 'DBH'], "Parkinson's disease pathway": ['PARK7', 'SNCAIP', 'MIR18A', 'EPRS1', 'MIR375', 'GPR37', 'UBE2L6', 'MAPK14', 'DDC', 'HTRA2', 'APAF1', 'LRRK2', 'CCNE1', 'CASP2', 'CASP3', 'CASP6', 'CASP7', 'CASP9', 'MAPK12', 'PINK1', 'SLC6A3', 'TH', 'UBB', 'PRKN', 'CYCS', 'MAPK11', 'MAPK13', 'MIR34B', 'MIRLET7G', 'MIR34C', 'MIR26B', 'MIR195', 'MIR26A1', 'MIR26A2', 'MIR16-2', 'CCNE2', 'ATXN2', 'MIR503', 'SYT11', 'MIR370', 'MIR19A', 'MIR19B1', 'SEPTIN5', 'MIR132', 'SNCA', 'UCHL1', 'MIR338', 'UBE2J1', 'UBA1', 'UBA7', 'UBE2G1', 'UBE2G2', 'UBE2L3', 'MIR212', 'UBE2J2', 'MIR128-1', 'MIR30A', 'MIR431', 'MIR19B2', 'MIR1224', 'MIR4448', 'MIR10A', 'MIR136', 'MIR485', 'MIR873', 'MIR409', 'MIR433', 'MIR127', 'MIR30E', 'MIR1294', 'MIR128-2'], 'Post-COVID neuroinflammation': [], 'Matrix metalloproteinases': ['MMP2', 'MMP14', 'TIMP2', 'MMP9', 'TNF', 'MMP28', 'MMP7', 'MMP3', 'MMP10', 'MMP8', 'MMP12', 'MMP11', 'MMP13', 'MMP1', 'MMP19', 'MMP15', 'TIMP1', 'TIMP3', 'MMP25', 'MMP20', 'TIMP4', 'TCF20', 'MMP24', 'MMP16', 'MMP21', 'MMP17', 'MMP27', 'MMP26', 'MMP23B', 'BSG'], 'Pleural mesothelioma': ['CDH10', 'CD44', 'MAD1L1', 'CTNNA3', 'SETD5', 'FABP4', 'TNIK', 'LATS2', 'CDH12', 'SETDB1', 'CDH24', 'CIT', 'CDH15', 'AMOT', 'TELO2', 'TTI1', 'CDH20', 'CD274', 'HMGN1', 'CDH19', 'CDH7', 'ULK2', 'WNT16', 'CSNK2A3', 'CDKN1A', 'TEAD3', 'MAP3K9', 'NOTUM', 'KREMEN1', 'NTF3', 'ROR1', 'FOSL1', 'FRAT2', 'CSNK1A1L', 'CSNK1E', 'NTF4', 'RYK', 'SOX17', 'SENP2', 'WIF1', 'DKK2', 'FRAT1', 'ROR2', 'CXXC4', 'SFRP5', 'SFRP4', 'MAX', 'NDRG1', 'PRSS23', 'KIF23', 'AJUBA', 'CER1', 'SFRP2', 'MTOR', 'MMP14', 'MKNK1', 'DKK4', 'SFRP1', 'CHD8', 'MKNK2', 'PORCN', 'EIF4EBP1', 'EIF4G1', 'MMP2', 'GSK3B', 'PAK3', 'MAP3K4', 'BAX', 'ITGA6', 'LAMB1', 'MAP2K4', 'MAP2K7', 'MAP4K4', 'CSNK2A2', 'ACTB', 'TEAD2', 'CDH1', 'MAP2K3', 'PIK3CB', 'LAMC2', 'CTNNA1', 'MAPK9', 'MAP4K3', 'RB1CC1', 'WWTR1', 'BAK1', 'BRCA1', 'IGF1', 'SOS1', 'SLC2A1', 'AKT3', 'ATF2', 'MEF2D', 'RPS6KA1', 'FN1', 'STAT1', 'WNT5A', 'PRKAG3', 'CCND1', 'PPARGC1A', 'PRKAB1', 'NFKB1', 'MAPK10', 'VEGFA', 'MAPK14', 'HBEGF', 'RPS6KB1', 'CCL2', 'DKK1', 'FGF8', 'MAP2K6', 'RHEB', 'PIK3CG', 'TGFB1', 'ACTA2', 'CXCL12', 'PRKAG2', 'MAPK8', 'MAP4K1', 'STK3', 'CCNE1', 'BBC3', 'AKT2', 'RPS6KA5', 'YY1', 'AXIN1', 'MAPK3', 'TSC2', 'CSNK2A1', 'MMP9', 'PAK5', 'MAP3K1', 'HIF1A', 'MAPK1', 'WNT1', 'IL1B', 'MAP2K2', 'BECN1', 'ELK1', 'CREB1', 'CDK2', 'PIK3CA', 'CCND2', 'CTNNB1', 'MAP2K1', 'WNT10B', 'MAP4K2', 'LGALS9', 'MAPK7', 'TSC1', 'SOST', 'CTHRC1', 'CSF2', 'VEGFD', 'MLST8', 'JAK1', 'TGFA', 'ACTG2', 'SHC1', 'ITGB2', 'PRKAA2', 'LRP5', 'CXCL1', 'CXCL5', 'SAV1', 'FOXO1', 'VEGFC', 'ACTC1', 'LIMD1', 'EGFR', 'ACTA1', 'MCL1', 'PAK1', 'CDKN2A', 'ITGB1', 'ATM', 'TP53', 'MINK1', 'RPTOR', 'BARD1', 'MAP3K6', 'AKT1', 'RPS6', 'MYC', 'PAK6', 'YAP1', 'MAP2K5', 'CASP1', 'MDM2', 'CDK4', 'IL10', 'LAMC1', 'IL6', 'PRKAA1', 'RAF1', 'NGF', 'ITGB4', 'SERPINF1', 'PAK4', 'IDO1', 'PRKAB2', 'MAP3K10', 'LAMA5', 'LATS1', 'TCF7', 'EED', 'EZH2', 'PLCB4', 'AREG', 'CCL5', 'INS', 'ITGB3', 'MDM4', 'TEAD4', 'CSNK2B', 'MAP3K3', 'NF2', 'SP1', 'TEAD1', 'MAP3K5', 'SRC', 'HMGB1', 'PAK2', 'PRKAG1', 'ACTG1', 'CSF1', 'HRAS', 'RPS6KA3', 'ULK1', 'JUN', 'ATG13', 'BDNF', 'RPS6KB2', 'LAMB2', 'BCL2', 'MST1', 'VEGFB', 'CYCS', 'MAP3K11', 'INSR', 'PIK3CD', 'MAP3K2', 'SPARC', 'LAMA4', 'PDGFRB', 'FGF1', 'FZD10', 'FGF6', 'PHC1', 'ITGA4', 'FGF12', 'DVL1', 'WNT3', 'CSF3', 'WNT2', 'WNT5B', 'FGF9', 'FGF14', 'FZD3', 'FLT1', 'LAMA1', 'FGF21', 'MET', 'FLT3LG', 'EFNA2', 'ANGPT2', 'WNT11', 'E2F1', 'PDGFB', 'ANGPT4', 'FGF22', 'FGF10', 'FGF4', 'COL4A4', 'FGFR1', 'FGF20', 'LAMC3', 'CUL1', 'LAMA3', 'FGFR3', 'RASSF1', 'LRP6', 'EIF4B', 'FGFR2', 'NGFR', 'HGF', 'KITLG', 'FLT4', 'YWHAB', 'ITGA3', 'DVL2', 'CD47', 'AGER', 'MIRLET7B', 'PRB1', 'MAPKAPK2', 'ATF3', 'CDH2', 'DDIT3', 'BTC', 'TCF7L1', 'TCF7L2', 'NLRP3', 'RBBP4', 'CCND3', 'LEF1', 'CSNK1A1', 'HCFC1', 'PTEN', 'CTBP2', 'PTK2', 'CXCL10', 'EFNA1', 'BMI1', 'ASXL1', 'PDGFD', 'MAD2L1', 'BAP1', 'ITGA2', 'TERT', 'BTRC', 'FZD6', 'CTBP1', 'FGF17', 'DVL3', 'FGFR4', 'FZD5', 'FGF19', 'FGF11', 'WNT4', 'WNT7A', 'DEPTOR', 'FZD7', 'FZD1', 'FGF18', 'KIT', 'EFNA3', 'PDK1', 'MMP3', 'WNT3A', 'ANGPT1', 'PDGFC', 'NTRK2', 'OGT', 'WNT10A', 'ITGAV', 'CDH11', 'IGF1R', 'EPHA2', 'FGF2', 'FGF5', 'FGF7', 'EGF', 'PDGFRA', 'APC', 'COL4A2', 'WNT2B', 'CDK7', 'FLT3', 'RNF2', 'PLAU', 'KDR', 'TRAF2', 'FGF13', 'FGF23', 'CCN2', 'TEK', 'PGF', 'WNT6', 'FGF3', 'CSF1R', 'EFNA5', 'LAMA2', 'FZD9', 'PDGFA', 'LAMB3', 'WNT7B', 'COL4A1', 'GRB2', 'FZD2', 'SUZ12', 'FZD8', 'UHRF1', 'GABPA', 'KDM6A', 'IL34', 'ADAMTS1', 'CDH13', 'WDR5', 'COL4A3', 'SLC3A2', 'COL4A5', 'SETD2', 'CDH4', 'MOB1B', 'LIN28B', 'CDH5', 'PODXL', 'FOXM1', 'KMT2C', 'STK38L', 'SLC7A5', 'ITPR3', 'VGLL4', 'CDH22', 'CDH18', 'IGF2', 'CDH16', 'RASSF6', 'PIGF', 'CDH8', 'MCU', 'RASSF3', 'RASSF7', 'TNNT1', 'RASSF2', 'WWC1', 'CDH6', 'DSC3', 'MOB1A', 'MDK', 'RASSF4', 'CDH9', 'BAG2', 'CDH3', 'SELE', 'CDH17', 'CTNNA2', 'NTRK1', 'COL4A6', 'AKT1S1', 'RING1', 'RASSF5', 'CCL4', 'EFNA4', 'ITGA1'], 'Immune response to tuberculosis': ['JAK2', 'TYK2', 'STAT1', 'JAK1', 'STAT2', 'SOCS1', 'IRF9', 'MX1', 'IFIT1', 'IFITM1', 'IFNGR1', 'PIAS1', 'IFNAR2', 'IFNGR2', 'IFNAR1', 'PSMB8', 'OAS1', 'IFI35', 'IFIT3', 'IRF1', 'TAP1', 'PTPN2', 'MED14']}
Section 3: Creation of KEgenes dictionary
In this section, you will identify the match between the dictKE and dictWP dictionary which will allow for matching between the keys: KE ID from the dictKE to the values:genes from dictWP.
Step 9. The KE_genes_dictionary dictionary will contain the match between the dictKE and dictWP dictionary by adding the values of the dictWP dictionary if the value: WPtitle of dictKE is present in dictWP.
KE_genes_dictionary=[]
for KEID in dictKE:
WPtitle= KEID['WPtitle']
if WPtitle in dictWP:
KEID['gene'] = dictWP[WPtitle]
KE_genes_dictionary.append(KEID)
print(KE_genes_dictionary)
[{'KEID': 'https://identifiers.org/aop.events/486', 'WPtitle': 'Overview of proinflammatory and profibrotic mediators', 'gene': ['IL25', 'IL12A', 'CXCL8', 'IL13', 'CSF1', 'IFNL2', 'IL17D', 'IFNL1', 'IL3', 'CSF2', 'CXCL1', 'CXCL5', 'IL1B', 'IL17C', 'IL17B', 'IL10', 'IL6', 'IFNG', 'IL17A', 'VEGFA', 'IL17F', 'IL23A', 'IL12B', 'IL5', 'IL4', 'CCL20', 'MMP9', 'TGFB1', 'CXCL12', 'CCL2', 'IL2', 'CCL3L1', 'CCL28', 'CTF1', 'IL33', 'CCL1', 'SPP1', 'EPO', 'LIF', 'MMP3', 'PF4', 'PPBP', 'LTA', 'EBI3', 'CSF3', 'CXCL2', 'IL7', 'OSM', 'IL22', 'CCL27', 'IL31', 'CCL15', 'CNTF', 'CXCL11', 'CXCL3', 'IL18', 'CXCL16', 'CXCL13', 'TNFSF13', 'AREG', 'IL1A', 'IL11', 'CCL22', 'TNFSF13B', 'CCL8', 'CXCL9', 'IL21', 'IL9', 'CXCL6', 'CCL21', 'NFKB1', 'CCL26', 'IFNL3', 'TNF', 'CCL5', 'IL26', 'CCL18', 'CCL4L2', 'CCL14', 'IFNW1', 'CCL13', 'IFNK', 'TSLP', 'IL24', 'IL20', 'CCL16', 'CCL23', 'CXCL17', 'IL36RN', 'IL36A', 'IL1F10', 'IL36B', 'XCL2', 'IL37', 'IL36G', 'PF4V1', 'CCL11', 'MMP1', 'IFNB1', 'CXCL10', 'IFNA7', 'CCL3', 'CCL4', 'IL27', 'IFNA14', 'IFNA1', 'IFNA17', 'IFNA13', 'IFNA4', 'IFNA5', 'IFNA16', 'IFNA2', 'IFNA10', 'IL19', 'IL15', 'IFNA6', 'IFNA8', 'IFNA21', 'IL1RN', 'XCL1', 'CXCL14', 'CCL19', 'CCL25', 'CCL7', 'CCL24', 'CX3CL1', 'CCL17']}, {'KEID': 'https://identifiers.org/aop.events/875', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/2007', 'WPtitle': 'miRNAs involved in DNA damage response', 'gene': ['CDKN1A', 'MIR92A1', 'MIR18A', 'MYC', 'ATM', 'ABL1', 'H2AX', 'MIR145', 'MIR29B1', 'CREB1', 'CDKN1B', 'MIR143', 'CCNE1', 'TP53', 'RAD52', 'CCND1', 'MIRLET7D', 'MIRLET7F1', 'MIR34C', 'MIRLET7A1', 'MIR23B', 'MIR20A', 'MIR106B', 'MIR424', 'MIR195', 'MIR330', 'MIR17', 'MIR449B', 'MIR222', 'MIR181B1', 'MIR449A', 'MIR421', 'MIR373', 'E2F1', 'MIRLET7B', 'CDK6', 'MIR34B', 'MIR29C', 'MIR21', 'CCND3', 'CDC25A', 'MIR449C', 'MIR19B1', 'MIR100', 'MIR542', 'MIR374B', 'MIR503', 'MIR450B', 'MIR19A', 'MIR497', 'MIR3074', 'MIR450A2', 'MIR25', 'MIR93', 'MIR372', 'MIR371A', 'MIR210', 'MIR181A1', 'MIR203A', 'MIR27A', 'MIR223', 'MIR29A', 'MIR23A', 'MIR221', 'MIR15A', 'MIR16-1', 'MIR27B', 'MIR15B']}, {'KEID': 'https://identifiers.org/aop.events/2007', 'WPtitle': 'miRNA regulation of DNA damage response', 'gene': ['BID', 'BRCA1', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'CDKN1A', 'RAD52', 'PRKDC', 'PML', 'RPA2', 'RAD50', 'CASP3', 'PMAIP1', 'FANCD2', 'CHEK1', 'ATM', 'RAD17', 'CASP9', 'TP53', 'CDK4', 'MDM2', 'TNFRSF10B', 'CDK2', 'CCND2', 'APAF1', 'CDKN1B', 'RAD1', 'CCNG1', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CHEK2', 'H2AX', 'ATR', 'RAD9A', 'PIDD1', 'MYC', 'MRE11', 'NBN', 'MIR29B1', 'MIR145', 'CREB1', 'CDK1', 'CYCS', 'MIR421', 'MIR449A', 'MIR373', 'MIR222', 'MIR449B', 'MIR3591', 'ATRIP', 'TP53AIP1', 'CCNB3', 'TLK2', 'HUS1B', 'RFC1', 'E2F1', 'CCNB1', 'RB1', 'DDB2', 'CCNE2', 'CDK6', 'CCND3', 'CCNB2', 'GADD45A', 'CDK5', 'CDC25C', 'MIR34B', 'MIR21', 'MIR29C', 'MCM7', 'MIR20A', 'MIR106B', 'MIR17HG', 'MIR195', 'MIR424', 'MIR17', 'CDC20B', 'MIR330', 'MIR221', 'MIR16-1', 'MIR203A', 'MIR181A1', 'MIR223', 'MIR15A', 'MIR29A', 'MIR24-1', 'TLK1', 'SFN', 'MIR210', 'GADD45G', 'RRM2B', 'SESN1', 'GADD45B', 'CDC25A']}, {'KEID': 'https://identifiers.org/aop.events/1495', 'WPtitle': 'Cytosolic DNA-sensing pathway', 'gene': ['CASP1', 'RIPK1', 'IL6', 'RIPK3', 'IRF3', 'IL1B', 'NFKBIA', 'POLR2F', 'POLR2E', 'IKBKB', 'TRADD', 'ATG5', 'CASP10', 'CASP8', 'NLRX1', 'AIM2', 'NFKBIB', 'NFKB1', 'CCL5', 'CHUK', 'IRF7', 'IKBKG', 'IKBKE', 'TBK1', 'POLR2L', 'POLR2K', 'ATG12', 'FADD', 'POLR2H', 'IL18', 'PYCARD', 'ADAR', 'STING1', 'POLR1C', 'CGAS', 'POLR3F', 'IL33', 'MAVS', 'POLR3GL', 'TRIM25', 'POLR3G', 'DDX58', 'POLR3H', 'POLR3E', 'POLR3B', 'CYLD', 'IFNB1', 'IFNA7', 'RELA', 'CCL4', 'ISG15', 'POLR1D', 'POLR3C', 'CXCL10', 'POLR3D', 'POLR3K', 'POLR3A', 'CCL4L2', 'ZBP1', 'RNF125', 'IFNA8', 'IFNA6', 'IFNA21', 'IFNA17', 'IFNA16', 'IFNA14', 'IFNA13', 'IFNA10', 'IFNA4', 'IFNA2', 'IFNA1', 'IFNA5', 'TREX1']}, {'KEID': 'https://identifiers.org/aop.events/1495', 'WPtitle': 'Nod-like receptor (NLR) signaling', 'gene': ['ERBIN', 'CHUK', 'IKBKB', 'MAPK8', 'MAP3K7', 'IKBKG', 'CD40', 'EPHB2', 'RELA']}, {'KEID': 'https://identifiers.org/aop.events/1495', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1495', 'WPtitle': 'TLR4 signaling and tolerance', 'gene': ['TRAM1', 'TIRAP', 'TLR4', 'IL6', 'IRF3', 'TRAF3', 'NFKB1', 'TAB2', 'TAB1', 'MYD88', 'TRAF6', 'RIPK1', 'IKBKE', 'CXCL8', 'NFKBIA', 'TICAM1', 'IKBKG', 'IRAK3', 'TNF', 'CHUK', 'IKBKB', 'MAP3K7', 'IRAK4', 'IRAK1', 'TBK1', 'IRF7', 'INPP5D', 'IFNB1']}, {'KEID': 'https://identifiers.org/aop.events/105', 'WPtitle': 'Electron transport chain: OXPHOS system in mitochondria', 'gene': ['SLC25A6', 'SLC25A14', 'SLC25A27', 'MT-ND3', 'MT-ND4', 'MT-ND6', 'UCP3', 'MT-ND4L', 'MT-ND5', 'MT-ND2', 'COX11', 'COX8A', 'SDHA', 'COX5A', 'SDHC', 'SDHD', 'ATP5IF1', 'NDUFA11', 'NDUFA1', 'COX7A2', 'UQCRQ', 'COX6A2', 'COX7A1', 'NDUFS7', 'MT-CYB', 'UQCR10', 'NDUFA2', 'NDUFA3', 'NDUFA7', 'NDUFA8', 'NDUFA5', 'NDUFA6', 'NDUFB1', 'NDUFB2', 'NDUFA9', 'NDUFA10', 'UQCR11', 'MT-ND1', 'SLC25A5', 'COX17', 'COX7A2L', 'MT-CO2', 'MT-CO3', 'SCO1', 'NDUFA4', 'UQCRFS1', 'SURF1', 'UCP2', 'COX4I1', 'COX6B1', 'COX6C', 'COX5B', 'COX6A1', 'COX7B', 'COX7C', 'MT-CO1', 'UCP1', 'NDUFA13', 'SLC25A4', 'UQCRB', 'UQCRH', 'UQCRC1', 'UQCRC2', 'NDUFB4', 'NDUFB5', 'NDUFB3', 'NDUFB8', 'NDUFB10', 'NDUFB6', 'NDUFB7', 'NDUFS1', 'NDUFC1', 'NDUFC2', 'NDUFV1', 'NDUFS4', 'NDUFS2', 'NDUFS3', 'NDUFS8', 'NDUFV2', 'NDUFS5', 'NDUFS6', 'NDUFV3', 'NDUFA12', 'ATP5MF', 'NDUFB9', 'DMAC2L', 'ATP5F1E', 'MT-ATP8', 'MT-ATP6', 'NDUFAB1', 'ATP5F1B', 'ATP5F1A', 'ATP5F1D', 'ATP5F1C', 'ATP5MC1', 'ATP5PB', 'ATP5MC3', 'ATP5MC2', 'ATP5PF', 'ATP5ME', 'ATP5PO', 'COX15', 'ATP5MG', 'ATP5PD', 'SDHB']}, {'KEID': 'https://identifiers.org/aop.events/105', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/1816', 'WPtitle': 'Electron transport chain: OXPHOS system in mitochondria', 'gene': ['SLC25A6', 'SLC25A14', 'SLC25A27', 'MT-ND3', 'MT-ND4', 'MT-ND6', 'UCP3', 'MT-ND4L', 'MT-ND5', 'MT-ND2', 'COX11', 'COX8A', 'SDHA', 'COX5A', 'SDHC', 'SDHD', 'ATP5IF1', 'NDUFA11', 'NDUFA1', 'COX7A2', 'UQCRQ', 'COX6A2', 'COX7A1', 'NDUFS7', 'MT-CYB', 'UQCR10', 'NDUFA2', 'NDUFA3', 'NDUFA7', 'NDUFA8', 'NDUFA5', 'NDUFA6', 'NDUFB1', 'NDUFB2', 'NDUFA9', 'NDUFA10', 'UQCR11', 'MT-ND1', 'SLC25A5', 'COX17', 'COX7A2L', 'MT-CO2', 'MT-CO3', 'SCO1', 'NDUFA4', 'UQCRFS1', 'SURF1', 'UCP2', 'COX4I1', 'COX6B1', 'COX6C', 'COX5B', 'COX6A1', 'COX7B', 'COX7C', 'MT-CO1', 'UCP1', 'NDUFA13', 'SLC25A4', 'UQCRB', 'UQCRH', 'UQCRC1', 'UQCRC2', 'NDUFB4', 'NDUFB5', 'NDUFB3', 'NDUFB8', 'NDUFB10', 'NDUFB6', 'NDUFB7', 'NDUFS1', 'NDUFC1', 'NDUFC2', 'NDUFV1', 'NDUFS4', 'NDUFS2', 'NDUFS3', 'NDUFS8', 'NDUFV2', 'NDUFS5', 'NDUFS6', 'NDUFV3', 'NDUFA12', 'ATP5MF', 'NDUFB9', 'DMAC2L', 'ATP5F1E', 'MT-ATP8', 'MT-ATP6', 'NDUFAB1', 'ATP5F1B', 'ATP5F1A', 'ATP5F1D', 'ATP5F1C', 'ATP5MC1', 'ATP5PB', 'ATP5MC3', 'ATP5MC2', 'ATP5PF', 'ATP5ME', 'ATP5PO', 'COX15', 'ATP5MG', 'ATP5PD', 'SDHB']}, {'KEID': 'https://identifiers.org/aop.events/1816', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/1668 ', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1668 ', 'WPtitle': 'TLR4 signaling and tolerance', 'gene': ['TRAM1', 'TIRAP', 'TLR4', 'IL6', 'IRF3', 'TRAF3', 'NFKB1', 'TAB2', 'TAB1', 'MYD88', 'TRAF6', 'RIPK1', 'IKBKE', 'CXCL8', 'NFKBIA', 'TICAM1', 'IKBKG', 'IRAK3', 'TNF', 'CHUK', 'IKBKB', 'MAP3K7', 'IRAK4', 'IRAK1', 'TBK1', 'IRF7', 'INPP5D', 'IFNB1']}, {'KEID': 'https://identifiers.org/aop.events/244 ', 'WPtitle': 'Unfolded protein response', 'gene': ['MBTPS1', 'ATF4', 'MBTPS2', 'NFE2L2', 'HSPA5', 'PPP1R15A', 'XBP1', 'ATF6', 'EIF2S1', 'ERN1', 'DDIT3', 'EIF2AK3', 'BBC3', 'TNFRSF10B', 'IL1B', 'TP53', 'PMAIP1', 'BID', 'TXNIP', 'BCL2L11', 'BCL2', 'RTCB', 'CASP2']}, {'KEID': 'https://identifiers.org/aop.events/244 ', 'WPtitle': 'Cellular proteostasis', 'gene': ['PFDN6', 'VBP1', 'PFDN2', 'PFDN1', 'PFDN5', 'PFDN4']}, {'KEID': 'https://identifiers.org/aop.events/244 ', 'WPtitle': 'NRF2 pathway', 'gene': ['SLC6A20', 'SLC6A18', 'FTH1', 'GSTM4', 'SLC39A2', 'SLC39A13', 'SLC6A5', 'SLC5A10', 'SLC7A11', 'SLC2A13', 'SLC6A1', 'CBR3', 'CES5A', 'SLC5A11', 'CBR1', 'SLC2A6', 'SLC39A3', 'SLC2A5', 'MGST3', 'SLC39A6', 'SLC39A1', 'SLC2A12', 'SLC39A4', 'SLC39A12', 'SLC5A12', 'GSTA5', 'GPX2', 'ADH7', 'SLC6A9', 'MAFF', 'CYP4A11', 'GSTA4', 'SLC6A19', 'GSTA3', 'CES3', 'CES2', 'SLC2A14', 'CES4A', 'GCLC', 'UGT1A7', 'UGT1A4', 'CYP2A6', 'SLC5A8', 'SLC6A14', 'SRXN1', 'MAFG', 'SLC6A17', 'SLC2A7', 'SLC39A10', 'SLC2A10', 'TXNRD3', 'CES1', 'AGER', 'TXNRD1', 'SLC5A3', 'GPX3', 'SLC2A3', 'HGF', 'HMOX1', 'PDGFB', 'KEAP1', 'SERPINA1', 'UGT1A1', 'GSTA1', 'GSTA2', 'GSTM2', 'TGFBR2', 'SLC2A2', 'UGT1A6', 'UGT2B7', 'NQO1', 'FGF13', 'GSTM1', 'EPHA2', 'TXN', 'NRG1', 'SLC5A5', 'ABCC3', 'NFE2L2', 'ABCC4', 'HSP90AA1', 'HSP90AB1', 'TGFB2', 'UGT1A9', 'ABCC2', 'RXRA', 'SLC2A4', 'HSPA1A', 'G6PD', 'PGD', 'SLC6A3', 'TGFA', 'SQSTM1', 'SLC2A1', 'SLC5A7', 'HBEGF', 'TGFB1', 'SLC6A2', 'SLC39A14', 'GSR', 'SLC5A1', 'GGT1', 'GSTT2', 'SLC5A4', 'BLVRB', 'SLC39A9', 'EPHA3', 'SLC6A16', 'ME1', 'SLC6A15', 'SLC6A7', 'SLC6A13', 'GCLM', 'MGST2', 'GSTP1', 'FTL', 'SLC39A8', 'SLC5A6', 'SLC2A8', 'SLC5A2', 'SLC39A5', 'SLC6A6', 'SLC6A8', 'SLC6A11', 'DNAJB1', 'SLC2A11', 'SLC39A11', 'GSTM3', 'GSTM5', 'SLC5A9', 'PRDX6', 'PRDX1', 'EGR1', 'SLC2A9', 'SOD3', 'ALDH3A1', 'SLC6A4', 'PTGR1', 'ABCC5', 'SLC39A7', 'PPARD']}, {'KEID': 'https://identifiers.org/aop.events/244 ', 'WPtitle': 'NRF2-ARE regulation', 'gene': ['GSK3B', 'SRC', 'PRKCA', 'MAPK8', 'PIK3CA', 'INSR', 'CEBPB', 'FYN', 'MAF', 'SLC7A11', 'GCLM', 'RBX1', 'CUL3', 'AIMP2', 'YES1', 'KEAP1', 'NFE2L2', 'GCLC', 'EPHB2', 'NQO1', 'HMOX1', 'GSTA2', 'PGAM5']}, {'KEID': 'https://identifiers.org/aop.events/244 ', 'WPtitle': 'DNA damage response', 'gene': ['PML', 'PRKDC', 'CDKN1A', 'RAD52', 'BRCA1', 'BID', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'MRE11', 'MYC', 'NBN', 'PIDD1', 'RFC1', 'ATRIP', 'TP53AIP1', 'TLK2', 'CCNB3', 'HUS1B', 'CHEK1', 'RAD17', 'CASP3', 'CDK1', 'CYCS', 'RAD9A', 'ATR', 'CHEK2', 'H2AX', 'CREB1', 'TNFRSF10B', 'CDK2', 'CASP9', 'CDK4', 'MDM2', 'TP53', 'PMAIP1', 'AKT1', 'FANCD2', 'ATM', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CDKN1B', 'RAD1', 'RAD50', 'RPA2', 'CCND2', 'APAF1', 'RB1', 'CCNE2', 'CCNB2', 'CDC25C', 'CDK5', 'CDK6', 'CCND3', 'GADD45A', 'CCNB1', 'DDB2', 'E2F1', 'GADD45G', 'CDC25A', 'TLK1', 'GADD45B', 'SFN', 'RRM2B', 'SESN1']}, {'KEID': 'https://identifiers.org/aop.events/244 ', 'WPtitle': 'DNA damage response (only ATM dependent)', 'gene': ['FRAT1', 'LDLR', 'FOSL1', 'CDKN1A', 'BAD', 'BAK1', 'MAPK9', 'MAP3K1', 'ABL1', 'BIK', 'SOS2', 'MAP3K4', 'BAX', 'MAPK8', 'CDKN1B', 'TGFB1', 'FASLG', 'FOXO3', 'CAT', 'RAC2', 'SOS1', 'MDM2', 'RAC1', 'MAP3K7', 'G6PC1', 'PMAIP1', 'ATM', 'BCL2L11', 'TP53', 'SMAD4', 'SHC1', 'IRS1', 'HMGB1', 'INSR', 'BCL2', 'AKT2', 'AKT3', 'AKT1', 'RAC3', 'BBC3', 'CDKN2A', 'NFKB1', 'GSK3B', 'PIK3R4', 'HRAS', 'JUN', 'RHOA', 'MYC', 'CTNNB1', 'PIK3C2G', 'PIK3C3', 'PIK3CA', 'PIK3CB', 'PIK3CD', 'PIK3CG', 'PIK3R1', 'PIK3R2', 'NRAS', 'WNT16', 'PIK3C2A', 'CCND1', 'WNT1', 'WNT5A', 'WNT10B', 'AXIN1', 'PIK3R3', 'CCND2', 'MAPK10', 'PPP2R5C', 'MAPK1', 'PCK2', 'CCNG2', 'MLKL', 'LEF1', 'TCF7', 'TCF7L2', 'TCF7L1', 'CCND3', 'CDC42', 'APC', 'ERBB2', 'PDK1', 'SMAD3', 'PTEN', 'GRB2', 'NFKB2', 'DVL1', 'DVL2', 'DVL3', 'PIK3R5', 'PPP2R5E', 'WNT2', 'KRAS', 'PIK3C2B', 'PLAU', 'WNT4', 'WNT10A', 'WNT5B', 'WNT3A', 'WNT3', 'WNT6', 'WNT7A', 'WNT7B', 'WNT11', 'WNT2B', 'RBL2', 'TP73', 'BCL6', 'SCP2']}, {'KEID': 'https://identifiers.org/aop.events/1739', 'WPtitle': 'Soluble ACE2-mediated cell entry of SARS-CoV-2', 'gene': ['AVPR1B', 'ACE2', 'AGTR1', 'ADAM17']}, {'KEID': 'https://identifiers.org/aop.events/1739', 'WPtitle': 'Soluble ACE2-mediated cell entry of SARS-CoV-2', 'gene': ['AVPR1B', 'ACE2', 'AGTR1', 'ADAM17']}, {'KEID': 'https://identifiers.org/aop.events/1814 ', 'WPtitle': 'DNA damage response (only ATM dependent)', 'gene': ['FRAT1', 'LDLR', 'FOSL1', 'CDKN1A', 'BAD', 'BAK1', 'MAPK9', 'MAP3K1', 'ABL1', 'BIK', 'SOS2', 'MAP3K4', 'BAX', 'MAPK8', 'CDKN1B', 'TGFB1', 'FASLG', 'FOXO3', 'CAT', 'RAC2', 'SOS1', 'MDM2', 'RAC1', 'MAP3K7', 'G6PC1', 'PMAIP1', 'ATM', 'BCL2L11', 'TP53', 'SMAD4', 'SHC1', 'IRS1', 'HMGB1', 'INSR', 'BCL2', 'AKT2', 'AKT3', 'AKT1', 'RAC3', 'BBC3', 'CDKN2A', 'NFKB1', 'GSK3B', 'PIK3R4', 'HRAS', 'JUN', 'RHOA', 'MYC', 'CTNNB1', 'PIK3C2G', 'PIK3C3', 'PIK3CA', 'PIK3CB', 'PIK3CD', 'PIK3CG', 'PIK3R1', 'PIK3R2', 'NRAS', 'WNT16', 'PIK3C2A', 'CCND1', 'WNT1', 'WNT5A', 'WNT10B', 'AXIN1', 'PIK3R3', 'CCND2', 'MAPK10', 'PPP2R5C', 'MAPK1', 'PCK2', 'CCNG2', 'MLKL', 'LEF1', 'TCF7', 'TCF7L2', 'TCF7L1', 'CCND3', 'CDC42', 'APC', 'ERBB2', 'PDK1', 'SMAD3', 'PTEN', 'GRB2', 'NFKB2', 'DVL1', 'DVL2', 'DVL3', 'PIK3R5', 'PPP2R5E', 'WNT2', 'KRAS', 'PIK3C2B', 'PLAU', 'WNT4', 'WNT10A', 'WNT5B', 'WNT3A', 'WNT3', 'WNT6', 'WNT7A', 'WNT7B', 'WNT11', 'WNT2B', 'RBL2', 'TP73', 'BCL6', 'SCP2']}, {'KEID': 'https://identifiers.org/aop.events/1814 ', 'WPtitle': 'Cellular proteostasis', 'gene': ['PFDN6', 'VBP1', 'PFDN2', 'PFDN1', 'PFDN5', 'PFDN4']}, {'KEID': 'https://identifiers.org/aop.events/1814 ', 'WPtitle': 'Unfolded protein response', 'gene': ['MBTPS1', 'ATF4', 'MBTPS2', 'NFE2L2', 'HSPA5', 'PPP1R15A', 'XBP1', 'ATF6', 'EIF2S1', 'ERN1', 'DDIT3', 'EIF2AK3', 'BBC3', 'TNFRSF10B', 'IL1B', 'TP53', 'PMAIP1', 'BID', 'TXNIP', 'BCL2L11', 'BCL2', 'RTCB', 'CASP2']}, {'KEID': 'https://identifiers.org/aop.events/1814 ', 'WPtitle': 'DNA damage response', 'gene': ['PML', 'PRKDC', 'CDKN1A', 'RAD52', 'BRCA1', 'BID', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'MRE11', 'MYC', 'NBN', 'PIDD1', 'RFC1', 'ATRIP', 'TP53AIP1', 'TLK2', 'CCNB3', 'HUS1B', 'CHEK1', 'RAD17', 'CASP3', 'CDK1', 'CYCS', 'RAD9A', 'ATR', 'CHEK2', 'H2AX', 'CREB1', 'TNFRSF10B', 'CDK2', 'CASP9', 'CDK4', 'MDM2', 'TP53', 'PMAIP1', 'AKT1', 'FANCD2', 'ATM', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CDKN1B', 'RAD1', 'RAD50', 'RPA2', 'CCND2', 'APAF1', 'RB1', 'CCNE2', 'CCNB2', 'CDC25C', 'CDK5', 'CDK6', 'CCND3', 'GADD45A', 'CCNB1', 'DDB2', 'E2F1', 'GADD45G', 'CDC25A', 'TLK1', 'GADD45B', 'SFN', 'RRM2B', 'SESN1']}, {'KEID': 'https://identifiers.org/aop.events/1740', 'WPtitle': 'Downregulation of ACE2 by SARS-CoV-2 spike protein', 'gene': ['ACE', 'AGTR1', 'AGTR2', 'ACE2']}, {'KEID': 'https://identifiers.org/aop.events/888', 'WPtitle': 'Mitochondrial complex I assembly model OXPHOS system', 'gene': ['NDUFAF1', 'NDUFB9', 'ACAD9', 'NDUFAB1', 'ECSIT', 'COA1', 'TIMMDC1', 'FOXRED1', 'DMAC1', 'NDUFAF3', 'TMEM70', 'NUBPL', 'TMEM186', 'MT-ND6', 'NDUFAF6', 'NDUFAF7', 'TMEM126B', 'MT-ND2', 'MT-ND4L', 'MT-ND4', 'MT-ND5', 'DMAC2', 'NDUFAF4', 'NDUFA2', 'NDUFS5', 'NDUFS2', 'NDUFS6', 'NDUFS4', 'NDUFB5', 'NDUFB3', 'NDUFC1', 'NDUFA1', 'NDUFB1', 'MT-ND1', 'NDUFAF2', 'NDUFA13', 'NDUFB11', 'NDUFA12', 'NDUFA8', 'NDUFV3', 'NDUFA6', 'NDUFA5', 'NDUFB7', 'NDUFV2', 'NDUFS1', 'NDUFV1', 'NDUFC2', 'NDUFA10', 'NDUFB10', 'NDUFB4', 'NDUFB8', 'NDUFB2', 'NDUFA7', 'NDUFS3', 'NDUFB6', 'NDUFA3']}, {'KEID': 'https://identifiers.org/aop.events/1584 ', 'WPtitle': '-', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1574', 'WPtitle': 'Canonical NF-kB pathway', 'gene': ['NFKB1', 'NFKBIA', 'IKBKB', 'NFKBIE', 'CHUK', 'IKBKG', 'RELA', 'REL']}, {'KEID': 'https://identifiers.org/aop.events/41', 'WPtitle': 'Farnesoid X receptor pathway', 'gene': ['UGT2B4', 'IRS2', 'SLC27A5', 'CYP8B1', 'IP6K3', 'ABCB4', 'NR0B2', 'SULT2A1', 'NR1H4', 'FGF19', 'BAAT', 'SLC10A1', 'ABCB11', 'SLCO2B1', 'RXRA', 'CYP7A1', 'CYP3A4', 'PPARGC1A', 'FKBP5']}, {'KEID': 'https://identifiers.org/aop.events/41', 'WPtitle': 'Cholestasis', 'gene': ['ATP8B1', 'HMGCR', 'LDLR', 'ABCC2', 'SCARB1', 'ABCG8', 'RXRA', 'TJP2', 'ABCG5', 'SLC22A1', 'ABCB4', 'NR1I3', 'SLC10A1', 'NR1H4', 'SLCO1A2', 'EPHX1', 'ABCC3', 'ABCB11', 'ABCC4']}, {'KEID': 'https://identifiers.org/aop.events/41', 'WPtitle': 'AMP-activated protein kinase signaling', 'gene': ['GYS1', 'AKT2', 'RPS6KB1', 'PIK3R2', 'PIK3CG', 'ADRA1A', 'PIK3CA', 'CAMKK2', 'PIK3R3', 'CCNA1', 'CCNA2', 'PIK3R1', 'TP53', 'AKT1', 'INSR', 'TSC1', 'FASN', 'ADIPOQ', 'CPT1B', 'TSC2', 'CDKN1A', 'SREBF1', 'PIK3C3', 'CAMKK1', 'PIK3CB', 'EEF2K', 'ADRA1B', 'MTOR', 'EIF4EBP1', 'HMGCR', 'LEP', 'RPS6KB2', 'PIK3CD', 'SLC2A4', 'PRKAA2', 'PRKAB1', 'PRKAG3', 'PRKAA1', 'PRKAB2', 'PRKAG2', 'RPTOR', 'PRKAG1', 'CPT1A', 'STRADB', 'CAB39', 'PFKFB3', 'PRKACB', 'PRKACG', 'ACACA', 'ELAVL1', 'LIPE', 'STK11', 'CCNB1', 'GYS2', 'PPARGC1B', 'PLCB1', 'STRADA', 'CRTC2', 'HNF4A', 'LEPR', 'ACACB', 'EEF2', 'ADIPOR2', 'INS-IGF2', 'ADIPOR1', 'CPT1C', 'SLC2A4RG']}, {'KEID': 'https://identifiers.org/aop.events/41', 'WPtitle': 'NRF2-ARE regulation', 'gene': ['GSK3B', 'SRC', 'PRKCA', 'MAPK8', 'PIK3CA', 'INSR', 'CEBPB', 'FYN', 'MAF', 'SLC7A11', 'GCLM', 'RBX1', 'CUL3', 'AIMP2', 'YES1', 'KEAP1', 'NFE2L2', 'GCLC', 'EPHB2', 'NQO1', 'HMOX1', 'GSTA2', 'PGAM5']}, {'KEID': 'https://identifiers.org/aop.events/41', 'WPtitle': 'NRF2 pathway', 'gene': ['SLC6A20', 'SLC6A18', 'FTH1', 'GSTM4', 'SLC39A2', 'SLC39A13', 'SLC6A5', 'SLC5A10', 'SLC7A11', 'SLC2A13', 'SLC6A1', 'CBR3', 'CES5A', 'SLC5A11', 'CBR1', 'SLC2A6', 'SLC39A3', 'SLC2A5', 'MGST3', 'SLC39A6', 'SLC39A1', 'SLC2A12', 'SLC39A4', 'SLC39A12', 'SLC5A12', 'GSTA5', 'GPX2', 'ADH7', 'SLC6A9', 'MAFF', 'CYP4A11', 'GSTA4', 'SLC6A19', 'GSTA3', 'CES3', 'CES2', 'SLC2A14', 'CES4A', 'GCLC', 'UGT1A7', 'UGT1A4', 'CYP2A6', 'SLC5A8', 'SLC6A14', 'SRXN1', 'MAFG', 'SLC6A17', 'SLC2A7', 'SLC39A10', 'SLC2A10', 'TXNRD3', 'CES1', 'AGER', 'TXNRD1', 'SLC5A3', 'GPX3', 'SLC2A3', 'HGF', 'HMOX1', 'PDGFB', 'KEAP1', 'SERPINA1', 'UGT1A1', 'GSTA1', 'GSTA2', 'GSTM2', 'TGFBR2', 'SLC2A2', 'UGT1A6', 'UGT2B7', 'NQO1', 'FGF13', 'GSTM1', 'EPHA2', 'TXN', 'NRG1', 'SLC5A5', 'ABCC3', 'NFE2L2', 'ABCC4', 'HSP90AA1', 'HSP90AB1', 'TGFB2', 'UGT1A9', 'ABCC2', 'RXRA', 'SLC2A4', 'HSPA1A', 'G6PD', 'PGD', 'SLC6A3', 'TGFA', 'SQSTM1', 'SLC2A1', 'SLC5A7', 'HBEGF', 'TGFB1', 'SLC6A2', 'SLC39A14', 'GSR', 'SLC5A1', 'GGT1', 'GSTT2', 'SLC5A4', 'BLVRB', 'SLC39A9', 'EPHA3', 'SLC6A16', 'ME1', 'SLC6A15', 'SLC6A7', 'SLC6A13', 'GCLM', 'MGST2', 'GSTP1', 'FTL', 'SLC39A8', 'SLC5A6', 'SLC2A8', 'SLC5A2', 'SLC39A5', 'SLC6A6', 'SLC6A8', 'SLC6A11', 'DNAJB1', 'SLC2A11', 'SLC39A11', 'GSTM3', 'GSTM5', 'SLC5A9', 'PRDX6', 'PRDX1', 'EGR1', 'SLC2A9', 'SOD3', 'ALDH3A1', 'SLC6A4', 'PTGR1', 'ABCC5', 'SLC39A7', 'PPARD']}, {'KEID': 'https://identifiers.org/aop.events/1270', 'WPtitle': 'PPAR signaling', 'gene': ['ACAA1', 'ACOX3', 'ACSL4', 'NR1H3', 'SCD', 'CPT1B', 'SLC27A6', 'FABP1', 'DBI', 'ACSBG1', 'HMGCS2', 'APOA5', 'ADIPOQ', 'ACSL1', 'LPL', 'CYP7A1', 'CD36', 'PDPK1', 'FADS2', 'RXRA', 'PCK1', 'CYP4A11', 'APOA2', 'ACSBG2', 'PPARD', 'ME1', 'ACADL', 'EHHADH', 'ACSL3', 'PLTP', 'PCK2', 'ILK', 'AQP7', 'ACOX2', 'PLIN1', 'FABP6', 'PPARA', 'CYP8B1', 'MMP1', 'UCP1', 'ACADM', 'APOA1', 'PPARG', 'CYP27A1', 'SLC27A2', 'SLC27A5', 'GK3P', 'FABP5', 'OLR1', 'APOC3', 'CPT1A', 'RXRB', 'RXRG', 'SLC27A4', 'FABP4', 'ACOX1', 'FABP2', 'ANGPTL4', 'ACSL6', 'ACSL5', 'CPT2', 'GK2', 'SCP2', 'SLC27A1', 'FABP3', 'SORBS1', 'CPT1C', 'FABP7']}, {'KEID': 'https://identifiers.org/aop.events/1086', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/1487 ', 'WPtitle': 'Glutathione metabolism', 'gene': ['GPX4', 'IDH1', 'GGT1', 'G6PD', 'GPX1', 'GPX2', 'GPX3', 'GSTA5', 'GCLM', 'GSR', 'GSTT2', 'GSTA1', 'GSTM1', 'GCLC', 'GSTM2', 'GGT5', 'OPLAH', 'ANPEP', 'GSS']}, {'KEID': 'https://identifiers.org/aop.events/1539', 'WPtitle': 'EGF/EGFR signaling', 'gene': ['IQSEC1', 'USP6NL', 'EPS8', 'REPS2', 'ATXN2', 'ERRFI1', 'MYBL2', 'CDC42', 'GAB2', 'RIN1', 'HGS', 'USP8', 'IQGAP1', 'STAM', 'RAB5A', 'PTK2', 'PTEN', 'PRKCZ', 'PLD2', 'PLD1', 'PLCG1', 'PIK3C2B', 'PLCE1', 'TWIST1', 'AURKA', 'STAT5B', 'STAT5A', 'BRAF', 'RAP1A', 'RALGDS', 'RALB', 'RALA', 'DNM1', 'RALBP1', 'CFL1', 'STAMBP', 'EGF', 'E2F1', 'NEDD8', 'NCK1', 'FOXO4', 'STMN1', 'KRAS', 'ARF6', 'GRB2', 'NOS3', 'GAB1', 'PIAS3', 'STAM2', 'INPP5D', 'AP2B1', 'AP2A1', 'AP2S1', 'SPRY2', 'PXDN', 'STXBP1', 'NDUFA13', 'PEBP1', 'NEDD4', 'LIMK2', 'SH3KBP1', 'EPS15L1', 'INPPL1', 'EPN1', 'EPS15', 'ABI1', 'AP2M1', 'PRKCI', 'MT-CO2', 'DOK2', 'PLSCR1', 'ASAP1', 'MTOR', 'EIF4EBP1', 'CSK', 'PTK2B', 'MAP3K3', 'MAP3K1', 'PAK1', 'MAP3K4', 'MEF2A', 'MEF2D', 'MEF2C', 'PDPK1', 'PCNA', 'MAPK1', 'PRKCB', 'MAPK7', 'MAPK4', 'PIK3R2', 'PIK3R1', 'PRKCA', 'MAPK8', 'MAPK14', 'ELK1', 'EGFR', 'CRK', 'CREB1', 'FOXO1', 'AKT1', 'FOS', 'GJA1', 'RICTOR', 'JAK1', 'HRAS', 'FOSB', 'ABL1', 'CBLC', 'JUN', 'JAK2', 'JUND', 'MAP4K1', 'MAP3K2', 'VAV3', 'PTPN5', 'PTPRR', 'ARHGEF1', 'SH3GL2', 'RASA1', 'RAF1', 'RPS6KA1', 'PTK6', 'MAP2K5', 'RAC1', 'PTPN11', 'MAPK9', 'MAP2K2', 'MAP2K1', 'STAT3', 'STAT1', 'SOS2', 'SOS1', 'SRC', 'SP1', 'RPS6KA3', 'RPS6KA2', 'SHC1', 'RPS6KB1', 'NCK2', 'ITCH', 'CAV2', 'CAV1', 'ATF1', 'ROCK1', 'PRKCD', 'SYNJ1', 'CRKL', 'ERBB2', 'ELK4', 'TNK2', 'GRB10', 'PTPN12', 'SH2D2A', 'SH3GL3', 'BCAR1', 'CBL', 'RPS6KA5', 'CBLB', 'VAV2', 'VAV1', 'NCOA3', 'CAMK2A']}, {'KEID': 'https://identifiers.org/aop.events/201', 'WPtitle': 'BDNF-TrkB signaling', 'gene': ['EIF4EBP1', 'EEF2K', 'MTOR', 'MKNK1', 'DLG4', 'TRPC6', 'TRPC3', 'TSC2', 'MAPK1', 'PIK3CG', 'RHEB', 'RPS6KB1', 'RPS6KA1', 'CREB1', 'SOS1', 'SHC1', 'AKT1', 'HRAS', 'BDNF', 'TSC1', 'MAP2K1', 'NRAS', 'ARC', 'GAB1', 'GAB2', 'KRAS', 'NTRK2', 'PLCG1', 'ADCY1', 'GRIN1', 'GRB2', 'BRAF', 'HOMER1']}, {'KEID': 'https://identifiers.org/aop.events/457', 'WPtitle': 'White fat cell differentiation (WP4149)', 'gene': ['KLF2', 'MECOM', 'EBF1', 'KLF15', 'KLF5', 'DDIT3', 'TCF7L1', 'INS', 'FOXO1', 'WNT10B', 'IRF3', 'TLE3', 'KLF4', 'CREB1', 'NR3C1', 'GATA3', 'CEBPD', 'CEBPA', 'SREBF1', 'CTNNA1', 'NR1H3', 'GATA2', 'RARA', 'PPARG', 'STAT5B', 'CEBPB', 'STAT5A', 'EGR2', 'RORA', 'NR2F2', 'ZNF423', 'IRF4']}, {'KEID': 'https://identifiers.org/aop.events/457', 'WPtitle': 'Transcriptional cascade regulating adipogenesis', 'gene': ['KLF2', 'DDIT3', 'KLF15', 'KLF5', 'CEBPG', 'GATA3', 'CEBPD', 'SREBF1', 'CEBPA', 'GATA2', 'PPARG', 'CEBPB', 'EGR2']}, {'KEID': 'https://identifiers.org/aop.events/457', 'WPtitle': 'Focal adhesion: PI3K-Akt-mTOR-signaling', 'gene': ['MTOR', 'EIF4EBP1', 'ITGB8', 'PIK3CG', 'COMP', 'PIK3R2', 'PPP2R1A', 'RHEB', 'JAK2', 'HSP90AB1', 'ITGA6', 'HIF1A', 'IL2RB', 'MAPK1', 'GYS1', 'PPP2CB', 'IKBKB', 'TSC2', 'MAPK3', 'AKT2', 'LAMC2', 'PIK3CB', 'GNB1', 'PPP2R5C', 'IL4R', 'SREBF1', 'ITGB5', 'GSK3B', 'HSP90AA1', 'LAMB1', 'IGF1', 'PIK3C2A', 'BAD', 'CDKN1A', 'TSC1', 'VEGFD', 'COL1A2', 'JAK1', 'PRKAA2', 'GNG8', 'GNGT2', 'RPTOR', 'EGFR', 'PIK3R1', 'AKT1', 'EIF4E', 'FOXO1', 'VEGFC', 'ITGB1', 'IL2RG', 'GNG3', 'ITGB2', 'CASP9', 'ITGB4', 'LAMC1', 'MDM2', 'IL2RA', 'NGF', 'IRS4', 'THBS1', 'PPP2R1B', 'RPS6', 'PDPK1', 'ITGB7', 'PIK3CA', 'FOXO3', 'GNG11', 'GNG13', 'PRKAA1', 'RAF1', 'LAMA5', 'FOXA1', 'GNGT1', 'MAP2K2', 'ITGB6', 'GNB4', 'PPP2CA', 'VEGFA', 'GNB3', 'CDKN1B', 'PPARGC1A', 'IL2', 'CREB1', 'SLC2A1', 'AKT3', 'EPAS1', 'ATF2', 'SOS1', 'FN1', 'VTN', 'COL1A1', 'RPS6KB1', 'FGF8', 'COL3A1', 'GNG4', 'MLST8', 'IKBKG', 'ITGB3', 'INS', 'GNG10', 'NRAS', 'ULK1', 'GNG7', 'RPS6KB2', 'HRAS', 'GNG5', 'SLC2A4', 'PIK3R4', 'GNG2', 'IRS2', 'CSF1', 'F2R', 'INSR', 'THBS3', 'IRS1', 'MAP2K1', 'VEGFB', 'GNG12', 'GNB2', 'PRL', 'LAMB2', 'PIK3CD', 'FGF4', 'PPP2R2C', 'PPP2R3A', 'FGF22', 'FGF10', 'ITGAE', 'PHLPP1', 'COL4A4', 'COL5A3', 'LIPE', 'FGF20', 'ITGA8', 'FGFR1', 'COL11A1', 'CREB3L3', 'SLC2A3', 'LAMA3', 'LAMC3', 'KITLG', 'TNC', 'PHLPP2', 'EIF4B', 'FLT4', 'PPP2R5B', 'FGFR3', 'FGFR2', 'ELAVL1', 'PPP2R5A', 'TBC1D1', 'LPAR2', 'NGFR', 'NOS2', 'ITGA2B', 'ITGA3', 'ITGAL', 'IBSP', 'HGF', 'CDC37', 'RAB2A', 'CREB3', 'MET', 'JAK3', 'FGF21', 'CSF3', 'GYS2', 'FGF6', 'VWF', 'ITGA10', 'EPHA2', 'COL6A2', 'IFNAR1', 'PIK3R5', 'ITGAX', 'IGF1R', 'FGF7', 'LPAR6', 'ANGPT1', 'PPP2R5E', 'PELO', 'LPAR4', 'CREB5', 'OSMR', 'PDGFC', 'ITGA9', 'EFNA3', 'CREB3L4', 'ITGA11', 'CSH1', 'CHAD', 'CAB39', 'EIF4E2', 'ITGA7', 'COL4A2', 'COL2A1', 'EGF', 'FGF2', 'ITGAV', 'KDR', 'HIF3A', 'PFKFB2', 'TNN', 'TEK', 'PGF', 'CSF3R', 'RAB14', 'ATF4', 'KRAS', 'PIK3C2B', 'COL5A1', 'EPO', 'FGF13', 'PDGFRA', 'PRLR', 'THBS4', 'GHR', 'LAMA4', 'PPP2R5D', 'PDGFRB', 'FGF1', 'TNR', 'ITGA4', 'FGF12', 'PFKFB4', 'SPP1', 'STK11', 'PDGFB', 'PIK3IP1', 'OSM', 'EFNA2', 'PPP2R3C', 'ANGPT2', 'NOS1', 'RAB10', 'FLT1', 'FGF9', 'CAB39L', 'FGF14', 'LAMA1', 'ANGPT4', 'TCL1A', 'FGF11', 'ITGA5', 'FGFR4', 'SLC2A2', 'FGF19', 'DDIT4', 'RAB8A', 'HSP90B1', 'NOS3', 'ITGA2', 'EFNA1', 'IL7R', 'CHRM1', 'TNXB', 'CREB3L1', 'KIT', 'ITGAD', 'PPP2R2B', 'FGF18', 'PFKFB1', 'CRTC2', 'IL6R', 'IFNAR2', 'FGF17', 'PTEN', 'IFNB1', 'LPAR3', 'PDGFD', 'PFKFB3', 'PTK2', 'EIF4E1B', 'PPP2R2D', 'CSF1R', 'CREB3L2', 'CHRM2', 'GRB2', 'EFNA5', 'COL4A1', 'EPOR', 'FGF3', 'THBS2', 'IL3RA', 'RAB11B', 'LPAR5', 'RELN', 'STRADA', 'ACACA', 'EFNA4', 'IFNA7', 'LAMB3', 'LAMA2', 'FGF16', 'ATF6B', 'TCL1B', 'AKT1S1', 'COL5A2', 'COL11A2', 'LPAR1', 'COL4A6', 'PDGFA']}, {'KEID': 'https://identifiers.org/aop.events/457', 'WPtitle': 'Cholesterol biosynthesis pathway in hepatocytes', 'gene': ['ABCG1', 'HMGCS1', 'CYP51A1', 'ACOT1', 'ELOVL3', 'ELOVL2', 'HMGCS2', 'NR1H2', 'SC5D', 'GGPS1', 'ACAT2', 'NSDHL', 'HSD17B7', 'LSS', 'PMVK', 'EBP', 'FDFT1', 'LBR', 'TM7SF2', 'IDI1', 'HMGCR', 'ELOVL4', 'SCD', 'MVD', 'CYP7A1', 'SREBF1', 'ACSL1', 'FADS2', 'IDI2', 'CYP27A1', 'CH25H', 'ABCA1', 'MYLIP', 'ACSL3', 'ELOVL5', 'MVK', 'NR1H3', 'FDPS', 'CYP46A1', 'MSMO1', 'ACOT2', 'DHCR24', 'PLPP6']}, {'KEID': 'https://identifiers.org/aop.events/457', 'WPtitle': 'Adipogenesis', 'gene': ['ADIPOQ', 'FOXC2', 'LMNA', 'GATA2', 'SFRP4', 'RARA', 'CDKN1A', 'CEBPA', 'ZMPSTE24', 'CEBPD', 'IL6', 'IRS1', 'INS', 'LPL', 'LEP', 'MEF2B', 'MEF2A', 'MEF2D', 'MEF2C', 'PCK1', 'AHR', 'EPAS1', 'FOXO1', 'GATA3', 'WWTR1', 'NR3C1', 'IGF1', 'HIF1A', 'FAS', 'CREB1', 'CTNNB1', 'NR1H3', 'PPARGC1A', 'NCOA2', 'BMP2', 'SCD', 'SLC2A4', 'BMP3', 'BMP4', 'RXRA', 'SOCS1', 'NCOA1', 'SOCS3', 'IRS2', 'WNT10B', 'IRS4', 'NRIP1', 'STAT1', 'SREBF1', 'STAT3', 'STAT2', 'TNF', 'TGFB1', 'WNT1', 'SP1', 'CYP26B1', 'PPARD', 'HMGA1', 'MIF', 'STAT6', 'PNPLA3', 'KLF7', 'GADD45A', 'DDIT3', 'GATA4', 'EBF1', 'GDF10', 'BSCL2', 'KLF15', 'MBNL1', 'GTF3A', 'NDN', 'ASIP', 'FRZB', 'PCK2', 'CISD1', 'KLF5', 'SPOCK1', 'MIXL1', 'NR2F1', 'AGPAT2', 'PLIN2', 'CELF1', 'ID3', 'RBL1', 'NAMPT', 'E2F4', 'RXRG', 'RBL2', 'GH1', 'LIF', 'IL6ST', 'LIPE', 'LIFR', 'SMAD3', 'OSM', 'SERPINE1', 'PPARA', 'PLIN1', 'PRLR', 'PPARG', 'CEBPB', 'CNTFR', 'CFD', 'KLF6', 'DVL1', 'AGT', 'E2F1', 'PTGIS', 'TRIB3', 'BMP1', 'RB1', 'STAT5B', 'STAT5A', 'TWIST1', 'HNF1A', 'WNT5B', 'FZD1', 'NCOR2', 'UCP1', 'RORA', 'LPIN3', 'LPIN2', 'RETN', 'GADD45B', 'NCOR1', 'DLK1', 'EGR2', 'CYP26A1', 'LPIN1']}, {'KEID': 'https://identifiers.org/aop.events/457', 'WPtitle': 'Liver X receptor pathway', 'gene': ['ABCG8', 'ABCG5', 'SCD', 'RXRA', 'SREBF1', 'CYP3A4', 'CYP7A1', 'CYP2B6', 'NR1H3', 'FASN']}, {'KEID': 'https://identifiers.org/aop.events/55', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/55', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/188', 'WPtitle': 'Neuroinflammation', 'gene': ['MTOR', 'CHUK', 'JUN', 'FOS', 'TLR4', 'NFKBIA', 'MAPK14', 'MAPK8', 'NOS2', 'MT-CO2', 'MT-CO1', 'RELA', 'ASCC1']}, {'KEID': 'https://identifiers.org/aop.events/618', 'WPtitle': 'mBDNF and proBDNF regulation of GABA neurotransmission', 'gene': ['SHC1', 'PIK3R1', 'CREB1', 'PIK3CA', 'PIK3R3', 'GABRA1', 'PIK3CB', 'RHOA', 'JAK2', 'PIK3R2', 'PIK3CG', 'STAT3', 'BDNF', 'GABRG2', 'ROCK1', 'GABRG1', 'AP2A1', 'AP2A2', 'CREM', 'GABRP', 'GABRE', 'AP2B1', 'PTEN', 'PLCG1', 'NTRK2', 'NGFR', 'GABRD', 'GABRG3', 'GABRQ', 'GABRA5', 'GABRB3', 'SLC12A5', 'GABRA3', 'GABRA6', 'GABRA4', 'GABRA2', 'GABRB2', 'GABRB1']}, {'KEID': 'https://identifiers.org/aop.events/618', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/618', 'WPtitle': 'GABA receptor signaling', 'gene': ['SLC32A1', 'GAD1', 'ABAT', 'GAD2', 'GABRA1', 'SLC6A11', 'GABRG2', 'ALDH9A1', 'GPHN', 'SLC6A1', 'GABBR2', 'AP2B1', 'AP2S1', 'GABRE', 'AP2A1', 'AP2A2', 'GABRP', 'GABRA3', 'GABRG1', 'GABRA4', 'GABRB2', 'AP2M1', 'GABRA2', 'GABRB3', 'GABRG3', 'GABRB1', 'GABRA5', 'GABRQ', 'GABRA6', 'GABBR1', 'GABRD']}, {'KEID': 'https://identifiers.org/aop.events/389', 'WPtitle': 'BDNF-TrkB signaling', 'gene': ['EIF4EBP1', 'EEF2K', 'MTOR', 'MKNK1', 'DLG4', 'TRPC6', 'TRPC3', 'TSC2', 'MAPK1', 'PIK3CG', 'RHEB', 'RPS6KB1', 'RPS6KA1', 'CREB1', 'SOS1', 'SHC1', 'AKT1', 'HRAS', 'BDNF', 'TSC1', 'MAP2K1', 'NRAS', 'ARC', 'GAB1', 'GAB2', 'KRAS', 'NTRK2', 'PLCG1', 'ADCY1', 'GRIN1', 'GRB2', 'BRAF', 'HOMER1']}, {'KEID': 'https://identifiers.org/aop.events/177', 'WPtitle': 'Electron transport chain: OXPHOS system in mitochondria', 'gene': ['SLC25A6', 'SLC25A14', 'SLC25A27', 'MT-ND3', 'MT-ND4', 'MT-ND6', 'UCP3', 'MT-ND4L', 'MT-ND5', 'MT-ND2', 'COX11', 'COX8A', 'SDHA', 'COX5A', 'SDHC', 'SDHD', 'ATP5IF1', 'NDUFA11', 'NDUFA1', 'COX7A2', 'UQCRQ', 'COX6A2', 'COX7A1', 'NDUFS7', 'MT-CYB', 'UQCR10', 'NDUFA2', 'NDUFA3', 'NDUFA7', 'NDUFA8', 'NDUFA5', 'NDUFA6', 'NDUFB1', 'NDUFB2', 'NDUFA9', 'NDUFA10', 'UQCR11', 'MT-ND1', 'SLC25A5', 'COX17', 'COX7A2L', 'MT-CO2', 'MT-CO3', 'SCO1', 'NDUFA4', 'UQCRFS1', 'SURF1', 'UCP2', 'COX4I1', 'COX6B1', 'COX6C', 'COX5B', 'COX6A1', 'COX7B', 'COX7C', 'MT-CO1', 'UCP1', 'NDUFA13', 'SLC25A4', 'UQCRB', 'UQCRH', 'UQCRC1', 'UQCRC2', 'NDUFB4', 'NDUFB5', 'NDUFB3', 'NDUFB8', 'NDUFB10', 'NDUFB6', 'NDUFB7', 'NDUFS1', 'NDUFC1', 'NDUFC2', 'NDUFV1', 'NDUFS4', 'NDUFS2', 'NDUFS3', 'NDUFS8', 'NDUFV2', 'NDUFS5', 'NDUFS6', 'NDUFV3', 'NDUFA12', 'ATP5MF', 'NDUFB9', 'DMAC2L', 'ATP5F1E', 'MT-ATP8', 'MT-ATP6', 'NDUFAB1', 'ATP5F1B', 'ATP5F1A', 'ATP5F1D', 'ATP5F1C', 'ATP5MC1', 'ATP5PB', 'ATP5MC3', 'ATP5MC2', 'ATP5PF', 'ATP5ME', 'ATP5PO', 'COX15', 'ATP5MG', 'ATP5PD', 'SDHB']}, {'KEID': 'https://identifiers.org/aop.events/177', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/177', 'WPtitle': 'Electron transport chain: OXPHOS system in mitochondria', 'gene': ['SLC25A6', 'SLC25A14', 'SLC25A27', 'MT-ND3', 'MT-ND4', 'MT-ND6', 'UCP3', 'MT-ND4L', 'MT-ND5', 'MT-ND2', 'COX11', 'COX8A', 'SDHA', 'COX5A', 'SDHC', 'SDHD', 'ATP5IF1', 'NDUFA11', 'NDUFA1', 'COX7A2', 'UQCRQ', 'COX6A2', 'COX7A1', 'NDUFS7', 'MT-CYB', 'UQCR10', 'NDUFA2', 'NDUFA3', 'NDUFA7', 'NDUFA8', 'NDUFA5', 'NDUFA6', 'NDUFB1', 'NDUFB2', 'NDUFA9', 'NDUFA10', 'UQCR11', 'MT-ND1', 'SLC25A5', 'COX17', 'COX7A2L', 'MT-CO2', 'MT-CO3', 'SCO1', 'NDUFA4', 'UQCRFS1', 'SURF1', 'UCP2', 'COX4I1', 'COX6B1', 'COX6C', 'COX5B', 'COX6A1', 'COX7B', 'COX7C', 'MT-CO1', 'UCP1', 'NDUFA13', 'SLC25A4', 'UQCRB', 'UQCRH', 'UQCRC1', 'UQCRC2', 'NDUFB4', 'NDUFB5', 'NDUFB3', 'NDUFB8', 'NDUFB10', 'NDUFB6', 'NDUFB7', 'NDUFS1', 'NDUFC1', 'NDUFC2', 'NDUFV1', 'NDUFS4', 'NDUFS2', 'NDUFS3', 'NDUFS8', 'NDUFV2', 'NDUFS5', 'NDUFS6', 'NDUFV3', 'NDUFA12', 'ATP5MF', 'NDUFB9', 'DMAC2L', 'ATP5F1E', 'MT-ATP8', 'MT-ATP6', 'NDUFAB1', 'ATP5F1B', 'ATP5F1A', 'ATP5F1D', 'ATP5F1C', 'ATP5MC1', 'ATP5PB', 'ATP5MC3', 'ATP5MC2', 'ATP5PF', 'ATP5ME', 'ATP5PO', 'COX15', 'ATP5MG', 'ATP5PD', 'SDHB']}, {'KEID': 'https://identifiers.org/aop.events/177', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/177', 'WPtitle': 'Electron transport chain: OXPHOS system in mitochondria', 'gene': ['SLC25A6', 'SLC25A14', 'SLC25A27', 'MT-ND3', 'MT-ND4', 'MT-ND6', 'UCP3', 'MT-ND4L', 'MT-ND5', 'MT-ND2', 'COX11', 'COX8A', 'SDHA', 'COX5A', 'SDHC', 'SDHD', 'ATP5IF1', 'NDUFA11', 'NDUFA1', 'COX7A2', 'UQCRQ', 'COX6A2', 'COX7A1', 'NDUFS7', 'MT-CYB', 'UQCR10', 'NDUFA2', 'NDUFA3', 'NDUFA7', 'NDUFA8', 'NDUFA5', 'NDUFA6', 'NDUFB1', 'NDUFB2', 'NDUFA9', 'NDUFA10', 'UQCR11', 'MT-ND1', 'SLC25A5', 'COX17', 'COX7A2L', 'MT-CO2', 'MT-CO3', 'SCO1', 'NDUFA4', 'UQCRFS1', 'SURF1', 'UCP2', 'COX4I1', 'COX6B1', 'COX6C', 'COX5B', 'COX6A1', 'COX7B', 'COX7C', 'MT-CO1', 'UCP1', 'NDUFA13', 'SLC25A4', 'UQCRB', 'UQCRH', 'UQCRC1', 'UQCRC2', 'NDUFB4', 'NDUFB5', 'NDUFB3', 'NDUFB8', 'NDUFB10', 'NDUFB6', 'NDUFB7', 'NDUFS1', 'NDUFC1', 'NDUFC2', 'NDUFV1', 'NDUFS4', 'NDUFS2', 'NDUFS3', 'NDUFS8', 'NDUFV2', 'NDUFS5', 'NDUFS6', 'NDUFV3', 'NDUFA12', 'ATP5MF', 'NDUFB9', 'DMAC2L', 'ATP5F1E', 'MT-ATP8', 'MT-ATP6', 'NDUFAB1', 'ATP5F1B', 'ATP5F1A', 'ATP5F1D', 'ATP5F1C', 'ATP5MC1', 'ATP5PB', 'ATP5MC3', 'ATP5MC2', 'ATP5PF', 'ATP5ME', 'ATP5PO', 'COX15', 'ATP5MG', 'ATP5PD', 'SDHB']}, {'KEID': 'https://identifiers.org/aop.events/177', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/2011', 'WPtitle': '-', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/2010', 'WPtitle': '-', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/2013', 'WPtitle': 'IL4 signaling', 'gene': ['ATF2', 'CHUK', 'HRH1', 'CEBPA', 'STAT1', 'STAT3', 'TYK2', 'BAD', 'PTPN6', 'PTPN11', 'SOS1', 'RPS6KB1', 'SHC1', 'PIK3R2', 'PIK3R1', 'NFKBIA', 'PIK3CD', 'PIK3CA', 'MAPK11', 'MAPK1', 'MAPK3', 'JAK1', 'JAK2', 'IRS1', 'NFKB1', 'IKBKB', 'BIRC5', 'IL4R', 'IL2RG', 'IL4', 'EP300', 'ELK1', 'AKT1', 'MAPK14', 'GATA3', 'FOS', 'RELA', 'STAT5B', 'STAT5A', 'JAK3', 'CEBPB', 'GRB2', 'FLNA', 'STAT6', 'IRS2', 'SOCS1', 'CBL', 'SOCS3', 'DOK2', 'GAB2', 'NFIL3', 'INPP5D', 'FES', 'SOCS5']}, {'KEID': 'https://identifiers.org/aop.events/2013', 'WPtitle': 'Airway smooth muscle cell contraction', 'gene': ['RYR1', 'GNAQ', 'IL13', 'RHOA', 'CALM1', 'GDI1', 'ROCK2', 'PPP1R14A', 'ROCK1', 'PLCB1', 'PPP1CB', 'MYL1', 'ADRB2', 'MYLK', 'CD38', 'ITPR3']}, {'KEID': 'https://identifiers.org/aop.events/2013', 'WPtitle': 'IL9 signaling', 'gene': ['CDK9', 'IL2RG', 'JAK1', 'PIK3R1', 'MAPK3', 'MAPK1', 'PIK3R2', 'MAP2K2', 'MAP2K1', 'STAT3', 'STAT1', 'IL9', 'IL9R', 'GRB2', 'JAK3', 'STAT5B', 'STAT5A']}, {'KEID': 'https://identifiers.org/aop.events/2006', 'WPtitle': 'DNA damage response (only ATM dependent)', 'gene': ['FRAT1', 'LDLR', 'FOSL1', 'CDKN1A', 'BAD', 'BAK1', 'MAPK9', 'MAP3K1', 'ABL1', 'BIK', 'SOS2', 'MAP3K4', 'BAX', 'MAPK8', 'CDKN1B', 'TGFB1', 'FASLG', 'FOXO3', 'CAT', 'RAC2', 'SOS1', 'MDM2', 'RAC1', 'MAP3K7', 'G6PC1', 'PMAIP1', 'ATM', 'BCL2L11', 'TP53', 'SMAD4', 'SHC1', 'IRS1', 'HMGB1', 'INSR', 'BCL2', 'AKT2', 'AKT3', 'AKT1', 'RAC3', 'BBC3', 'CDKN2A', 'NFKB1', 'GSK3B', 'PIK3R4', 'HRAS', 'JUN', 'RHOA', 'MYC', 'CTNNB1', 'PIK3C2G', 'PIK3C3', 'PIK3CA', 'PIK3CB', 'PIK3CD', 'PIK3CG', 'PIK3R1', 'PIK3R2', 'NRAS', 'WNT16', 'PIK3C2A', 'CCND1', 'WNT1', 'WNT5A', 'WNT10B', 'AXIN1', 'PIK3R3', 'CCND2', 'MAPK10', 'PPP2R5C', 'MAPK1', 'PCK2', 'CCNG2', 'MLKL', 'LEF1', 'TCF7', 'TCF7L2', 'TCF7L1', 'CCND3', 'CDC42', 'APC', 'ERBB2', 'PDK1', 'SMAD3', 'PTEN', 'GRB2', 'NFKB2', 'DVL1', 'DVL2', 'DVL3', 'PIK3R5', 'PPP2R5E', 'WNT2', 'KRAS', 'PIK3C2B', 'PLAU', 'WNT4', 'WNT10A', 'WNT5B', 'WNT3A', 'WNT3', 'WNT6', 'WNT7A', 'WNT7B', 'WNT11', 'WNT2B', 'RBL2', 'TP73', 'BCL6', 'SCP2']}, {'KEID': 'https://identifiers.org/aop.events/2006', 'WPtitle': 'DNA damage response', 'gene': ['PML', 'PRKDC', 'CDKN1A', 'RAD52', 'BRCA1', 'BID', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'MRE11', 'MYC', 'NBN', 'PIDD1', 'RFC1', 'ATRIP', 'TP53AIP1', 'TLK2', 'CCNB3', 'HUS1B', 'CHEK1', 'RAD17', 'CASP3', 'CDK1', 'CYCS', 'RAD9A', 'ATR', 'CHEK2', 'H2AX', 'CREB1', 'TNFRSF10B', 'CDK2', 'CASP9', 'CDK4', 'MDM2', 'TP53', 'PMAIP1', 'AKT1', 'FANCD2', 'ATM', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CDKN1B', 'RAD1', 'RAD50', 'RPA2', 'CCND2', 'APAF1', 'RB1', 'CCNE2', 'CCNB2', 'CDC25C', 'CDK5', 'CDK6', 'CCND3', 'GADD45A', 'CCNB1', 'DDB2', 'E2F1', 'GADD45G', 'CDC25A', 'TLK1', 'GADD45B', 'SFN', 'RRM2B', 'SESN1']}, {'KEID': 'https://identifiers.org/aop.events/1497', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1497', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1497', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/1497', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/1497', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/780', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/870', 'WPtitle': 'Growth factors and hormones in beta cell proliferation', 'gene': ['PDX1', 'MYC', 'INS', 'IGF1', 'INSR', 'FOXO1', 'AKT3', 'CDK4', 'CDK2', 'MAPK3', 'MAPK1', 'AKT1', 'AKT2', 'SMAD7', 'KRAS', 'PDGFA', 'IGF1R', 'BRAF', 'FLT1', 'TGFBR1', 'PGF', 'CRTC2', 'RASSF1', 'DLK1', 'FOXM1', 'RAB43']}, {'KEID': 'https://identifiers.org/aop.events/1669', 'WPtitle': 'DNA damage response', 'gene': ['PML', 'PRKDC', 'CDKN1A', 'RAD52', 'BRCA1', 'BID', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'MRE11', 'MYC', 'NBN', 'PIDD1', 'RFC1', 'ATRIP', 'TP53AIP1', 'TLK2', 'CCNB3', 'HUS1B', 'CHEK1', 'RAD17', 'CASP3', 'CDK1', 'CYCS', 'RAD9A', 'ATR', 'CHEK2', 'H2AX', 'CREB1', 'TNFRSF10B', 'CDK2', 'CASP9', 'CDK4', 'MDM2', 'TP53', 'PMAIP1', 'AKT1', 'FANCD2', 'ATM', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CDKN1B', 'RAD1', 'RAD50', 'RPA2', 'CCND2', 'APAF1', 'RB1', 'CCNE2', 'CCNB2', 'CDC25C', 'CDK5', 'CDK6', 'CCND3', 'GADD45A', 'CCNB1', 'DDB2', 'E2F1', 'GADD45G', 'CDC25A', 'TLK1', 'GADD45B', 'SFN', 'RRM2B', 'SESN1']}, {'KEID': 'https://identifiers.org/aop.events/1669', 'WPtitle': 'DNA damage response (only ATM dependent)', 'gene': ['FRAT1', 'LDLR', 'FOSL1', 'CDKN1A', 'BAD', 'BAK1', 'MAPK9', 'MAP3K1', 'ABL1', 'BIK', 'SOS2', 'MAP3K4', 'BAX', 'MAPK8', 'CDKN1B', 'TGFB1', 'FASLG', 'FOXO3', 'CAT', 'RAC2', 'SOS1', 'MDM2', 'RAC1', 'MAP3K7', 'G6PC1', 'PMAIP1', 'ATM', 'BCL2L11', 'TP53', 'SMAD4', 'SHC1', 'IRS1', 'HMGB1', 'INSR', 'BCL2', 'AKT2', 'AKT3', 'AKT1', 'RAC3', 'BBC3', 'CDKN2A', 'NFKB1', 'GSK3B', 'PIK3R4', 'HRAS', 'JUN', 'RHOA', 'MYC', 'CTNNB1', 'PIK3C2G', 'PIK3C3', 'PIK3CA', 'PIK3CB', 'PIK3CD', 'PIK3CG', 'PIK3R1', 'PIK3R2', 'NRAS', 'WNT16', 'PIK3C2A', 'CCND1', 'WNT1', 'WNT5A', 'WNT10B', 'AXIN1', 'PIK3R3', 'CCND2', 'MAPK10', 'PPP2R5C', 'MAPK1', 'PCK2', 'CCNG2', 'MLKL', 'LEF1', 'TCF7', 'TCF7L2', 'TCF7L1', 'CCND3', 'CDC42', 'APC', 'ERBB2', 'PDK1', 'SMAD3', 'PTEN', 'GRB2', 'NFKB2', 'DVL1', 'DVL2', 'DVL3', 'PIK3R5', 'PPP2R5E', 'WNT2', 'KRAS', 'PIK3C2B', 'PLAU', 'WNT4', 'WNT10A', 'WNT5B', 'WNT3A', 'WNT3', 'WNT6', 'WNT7A', 'WNT7B', 'WNT11', 'WNT2B', 'RBL2', 'TP73', 'BCL6', 'SCP2']}, {'KEID': 'https://identifiers.org/aop.events/1669', 'WPtitle': 'miRNAs involved in DNA damage response', 'gene': ['CDKN1A', 'MIR92A1', 'MIR18A', 'MYC', 'ATM', 'ABL1', 'H2AX', 'MIR145', 'MIR29B1', 'CREB1', 'CDKN1B', 'MIR143', 'CCNE1', 'TP53', 'RAD52', 'CCND1', 'MIRLET7D', 'MIRLET7F1', 'MIR34C', 'MIRLET7A1', 'MIR23B', 'MIR20A', 'MIR106B', 'MIR424', 'MIR195', 'MIR330', 'MIR17', 'MIR449B', 'MIR222', 'MIR181B1', 'MIR449A', 'MIR421', 'MIR373', 'E2F1', 'MIRLET7B', 'CDK6', 'MIR34B', 'MIR29C', 'MIR21', 'CCND3', 'CDC25A', 'MIR449C', 'MIR19B1', 'MIR100', 'MIR542', 'MIR374B', 'MIR503', 'MIR450B', 'MIR19A', 'MIR497', 'MIR3074', 'MIR450A2', 'MIR25', 'MIR93', 'MIR372', 'MIR371A', 'MIR210', 'MIR181A1', 'MIR203A', 'MIR27A', 'MIR223', 'MIR29A', 'MIR23A', 'MIR221', 'MIR15A', 'MIR16-1', 'MIR27B', 'MIR15B']}, {'KEID': 'https://identifiers.org/aop.events/1669', 'WPtitle': 'miRNA regulation of DNA damage response', 'gene': ['BID', 'BRCA1', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'CDKN1A', 'RAD52', 'PRKDC', 'PML', 'RPA2', 'RAD50', 'CASP3', 'PMAIP1', 'FANCD2', 'CHEK1', 'ATM', 'RAD17', 'CASP9', 'TP53', 'CDK4', 'MDM2', 'TNFRSF10B', 'CDK2', 'CCND2', 'APAF1', 'CDKN1B', 'RAD1', 'CCNG1', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CHEK2', 'H2AX', 'ATR', 'RAD9A', 'PIDD1', 'MYC', 'MRE11', 'NBN', 'MIR29B1', 'MIR145', 'CREB1', 'CDK1', 'CYCS', 'MIR421', 'MIR449A', 'MIR373', 'MIR222', 'MIR449B', 'MIR3591', 'ATRIP', 'TP53AIP1', 'CCNB3', 'TLK2', 'HUS1B', 'RFC1', 'E2F1', 'CCNB1', 'RB1', 'DDB2', 'CCNE2', 'CDK6', 'CCND3', 'CCNB2', 'GADD45A', 'CDK5', 'CDC25C', 'MIR34B', 'MIR21', 'MIR29C', 'MCM7', 'MIR20A', 'MIR106B', 'MIR17HG', 'MIR195', 'MIR424', 'MIR17', 'CDC20B', 'MIR330', 'MIR221', 'MIR16-1', 'MIR203A', 'MIR181A1', 'MIR223', 'MIR15A', 'MIR29A', 'MIR24-1', 'TLK1', 'SFN', 'MIR210', 'GADD45G', 'RRM2B', 'SESN1', 'GADD45B', 'CDC25A']}, {'KEID': 'https://identifiers.org/aop.events/1115', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/1097', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/202', 'WPtitle': 'Canonical NF-kB pathway', 'gene': ['NFKB1', 'NFKBIA', 'IKBKB', 'NFKBIE', 'CHUK', 'IKBKG', 'RELA', 'REL']}, {'KEID': 'https://identifiers.org/aop.events/202', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/202', 'WPtitle': 'Interleukin-1 induced activation of NF-kB', 'gene': ['AJUBA', 'SQSTM1', 'TRAF6', 'UBE2N', 'IRAK1', 'UBE2V1', 'NFKB1', 'IL1A', 'PRKCZ', 'TIFA']}, {'KEID': 'https://identifiers.org/aop.events/202', 'WPtitle': 'Interleukin-1 induced activation of NF-kB', 'gene': ['AJUBA', 'SQSTM1', 'TRAF6', 'UBE2N', 'IRAK1', 'UBE2V1', 'NFKB1', 'IL1A', 'PRKCZ', 'TIFA']}, {'KEID': 'https://identifiers.org/aop.events/202', 'WPtitle': 'Canonical NF-kB pathway', 'gene': ['NFKB1', 'NFKBIA', 'IKBKB', 'NFKBIE', 'CHUK', 'IKBKG', 'RELA', 'REL']}, {'KEID': 'https://identifiers.org/aop.events/202', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/1917', 'WPtitle': 'NRF2-ARE regulation', 'gene': ['GSK3B', 'SRC', 'PRKCA', 'MAPK8', 'PIK3CA', 'INSR', 'CEBPB', 'FYN', 'MAF', 'SLC7A11', 'GCLM', 'RBX1', 'CUL3', 'AIMP2', 'YES1', 'KEAP1', 'NFE2L2', 'GCLC', 'EPHB2', 'NQO1', 'HMOX1', 'GSTA2', 'PGAM5']}, {'KEID': 'https://identifiers.org/aop.events/1917', 'WPtitle': 'NRF2 pathway', 'gene': ['SLC6A20', 'SLC6A18', 'FTH1', 'GSTM4', 'SLC39A2', 'SLC39A13', 'SLC6A5', 'SLC5A10', 'SLC7A11', 'SLC2A13', 'SLC6A1', 'CBR3', 'CES5A', 'SLC5A11', 'CBR1', 'SLC2A6', 'SLC39A3', 'SLC2A5', 'MGST3', 'SLC39A6', 'SLC39A1', 'SLC2A12', 'SLC39A4', 'SLC39A12', 'SLC5A12', 'GSTA5', 'GPX2', 'ADH7', 'SLC6A9', 'MAFF', 'CYP4A11', 'GSTA4', 'SLC6A19', 'GSTA3', 'CES3', 'CES2', 'SLC2A14', 'CES4A', 'GCLC', 'UGT1A7', 'UGT1A4', 'CYP2A6', 'SLC5A8', 'SLC6A14', 'SRXN1', 'MAFG', 'SLC6A17', 'SLC2A7', 'SLC39A10', 'SLC2A10', 'TXNRD3', 'CES1', 'AGER', 'TXNRD1', 'SLC5A3', 'GPX3', 'SLC2A3', 'HGF', 'HMOX1', 'PDGFB', 'KEAP1', 'SERPINA1', 'UGT1A1', 'GSTA1', 'GSTA2', 'GSTM2', 'TGFBR2', 'SLC2A2', 'UGT1A6', 'UGT2B7', 'NQO1', 'FGF13', 'GSTM1', 'EPHA2', 'TXN', 'NRG1', 'SLC5A5', 'ABCC3', 'NFE2L2', 'ABCC4', 'HSP90AA1', 'HSP90AB1', 'TGFB2', 'UGT1A9', 'ABCC2', 'RXRA', 'SLC2A4', 'HSPA1A', 'G6PD', 'PGD', 'SLC6A3', 'TGFA', 'SQSTM1', 'SLC2A1', 'SLC5A7', 'HBEGF', 'TGFB1', 'SLC6A2', 'SLC39A14', 'GSR', 'SLC5A1', 'GGT1', 'GSTT2', 'SLC5A4', 'BLVRB', 'SLC39A9', 'EPHA3', 'SLC6A16', 'ME1', 'SLC6A15', 'SLC6A7', 'SLC6A13', 'GCLM', 'MGST2', 'GSTP1', 'FTL', 'SLC39A8', 'SLC5A6', 'SLC2A8', 'SLC5A2', 'SLC39A5', 'SLC6A6', 'SLC6A8', 'SLC6A11', 'DNAJB1', 'SLC2A11', 'SLC39A11', 'GSTM3', 'GSTM5', 'SLC5A9', 'PRDX6', 'PRDX1', 'EGR1', 'SLC2A9', 'SOD3', 'ALDH3A1', 'SLC6A4', 'PTGR1', 'ABCC5', 'SLC39A7', 'PPARD']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/1633', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/814', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1392', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/1392', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1392', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/1392', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1392', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/1392', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1815', 'WPtitle': 'Unfolded protein response', 'gene': ['MBTPS1', 'ATF4', 'MBTPS2', 'NFE2L2', 'HSPA5', 'PPP1R15A', 'XBP1', 'ATF6', 'EIF2S1', 'ERN1', 'DDIT3', 'EIF2AK3', 'BBC3', 'TNFRSF10B', 'IL1B', 'TP53', 'PMAIP1', 'BID', 'TXNIP', 'BCL2L11', 'BCL2', 'RTCB', 'CASP2']}, {'KEID': 'https://identifiers.org/aop.events/1815', 'WPtitle': 'Unfolded protein response', 'gene': ['MBTPS1', 'ATF4', 'MBTPS2', 'NFE2L2', 'HSPA5', 'PPP1R15A', 'XBP1', 'ATF6', 'EIF2S1', 'ERN1', 'DDIT3', 'EIF2AK3', 'BBC3', 'TNFRSF10B', 'IL1B', 'TP53', 'PMAIP1', 'BID', 'TXNIP', 'BCL2L11', 'BCL2', 'RTCB', 'CASP2']}, {'KEID': 'https://identifiers.org/aop.events/1943', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/386', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/386', 'WPtitle': 'mBDNF and proBDNF regulation of GABA neurotransmission', 'gene': ['SHC1', 'PIK3R1', 'CREB1', 'PIK3CA', 'PIK3R3', 'GABRA1', 'PIK3CB', 'RHOA', 'JAK2', 'PIK3R2', 'PIK3CG', 'STAT3', 'BDNF', 'GABRG2', 'ROCK1', 'GABRG1', 'AP2A1', 'AP2A2', 'CREM', 'GABRP', 'GABRE', 'AP2B1', 'PTEN', 'PLCG1', 'NTRK2', 'NGFR', 'GABRD', 'GABRG3', 'GABRQ', 'GABRA5', 'GABRB3', 'SLC12A5', 'GABRA3', 'GABRA6', 'GABRA4', 'GABRA2', 'GABRB2', 'GABRB1']}, {'KEID': 'https://identifiers.org/aop.events/386', 'WPtitle': 'Brain-derived neurotrophic factor (BDNF) signaling', 'gene': ['CREB1', 'CHUK', 'MAPK14', 'CTNNB1', 'CSNK2A1', 'VAV3', 'BCL2L11', 'MAP3K2', 'EIF4EBP1', 'MTOR', 'MAPT', 'ALPL', 'NFATC4', 'PTPRF', 'NTF3', 'GRIP1', 'PTK2B', 'DLG1', 'PRKAA2', 'PIK3R1', 'SHC3', 'PIK3R2', 'PRKAA1', 'PPP2CA', 'MAP3K1', 'NCAM1', 'JAK2', 'JUN', 'MEF2C', 'MEF2A', 'PDPK1', 'NCF2', 'NFKB1', 'NGF', 'NFKBIA', 'AKT1', 'FOXO3', 'FOS', 'EIF4E', 'ELK1', 'IKBKB', 'IRS1', 'SHC2', 'GSK3B', 'HRAS', 'FRS2', 'CFL1', 'VAV2', 'CAMK2A', 'CAMK4', 'SYN1', 'STAT3', 'TSC2', 'TRAF6', 'IRS2', 'SQSTM1', 'RPS6KA5', 'IKBKG', 'CASP3', 'RPS6', 'RPS6KA1', 'RPS6KA3', 'BDNF', 'RPS6KB1', 'RAF1', 'NCF1', 'SRC', 'STAT1', 'BMP2', 'SHC1', 'BAD', 'MAPK10', 'MAPK9', 'MAP2K1', 'MAP2K2', 'MAP2K5', 'PTPN11', 'RAB3A', 'RAC1', 'MAPK8', 'MAPK1', 'MAPK7', 'MAPK3', 'DOK5', 'PRKCD', 'NSF', 'CDK5R1', 'NCK2', 'MARCKS', 'EIF2S2', 'DOCK3', 'DPYSL2', 'SH2B1', 'CDKL5', 'RANBP9', 'GRIA3', 'GRIA2', 'YBX1', 'CDH2', 'CDK5', 'EGR1', 'SIRPA', 'EIF2S1', 'EEF2', 'CNR1', 'EGR2', 'NTRK3', 'RACK1', 'FRS3', 'LINGO1', 'KCNA3', 'CDC42', 'CRTC1', 'IGF2BP1', 'RHOG', 'CAMK1', 'KSR1', 'SH2B2', 'GABRB3', 'CYFIP1', 'ACACB', 'KCNN2', 'SPP1', 'KIDINS220', 'RASGRF1', 'RAP1A', 'RELA', 'SORT1', 'STAT5B', 'ADAM17', 'TIAM1', 'STAT5A', 'APC', 'SHC4', 'FYN', 'GRIA1', 'GRB2', 'GRIN2B', 'GRIN1', 'NGFR', 'NCK1', 'NTRK1', 'PLCG1', 'NTRK2']}, {'KEID': 'https://identifiers.org/aop.events/1944', 'WPtitle': 'Disruption of postsynaptic signaling by CNV', 'gene': ['GRM1', 'ARC', 'MAPK1', 'MAPK3', 'NRXN1', 'NRXN2', 'NRXN3', 'DLG2', 'SHANK1', 'GRIN2D', 'GRIN2C', 'YWHAG', 'CAMK2G', 'RPH3A', 'SYNGAP1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'NLGN1', 'HOMER1', 'CYFIP1', 'NLGN2', 'NLGN3', 'NLGN4X', 'DLG1', 'RYR2', 'DLGAP1', 'CAMK2B', 'STX1A', 'TJP1', 'FMR1', 'CAMK2A', 'CAMK2D']}, {'KEID': 'https://identifiers.org/aop.events/1582', 'WPtitle': 'Axon guidance', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1582', 'WPtitle': 'Microtubule cytoskeleton regulation', 'gene': ['GSK3B', 'ABL1', 'RHO', 'TAOK1', 'MAPT', 'PRKCA', 'CAMK4', 'GNAQ', 'AKT1', 'PAK1', 'STAT3', 'SRC', 'CDK1', 'PIK3CA', 'RAC1', 'F2RL2', 'CDC42', 'PRKACA', 'TRIO', 'PHLDB2', 'DIAPH1', 'TPPP', 'MAPKAPK2', 'CFL2', 'DPYSL2', 'SPRED1', 'CLASP1', 'TESK2', 'ROCK1', 'PTEN', 'AURKB', 'APC', 'WNT3A', 'TIAM1', 'DVL1', 'PARD6A', 'STMN1', 'PTPRA', 'CLIP1', 'EPHB2', 'MAPRE1', 'MAP1B', 'KIF2C', 'LIMK1', 'MARK2', 'MARK1']}, {'KEID': 'https://identifiers.org/aop.events/1942', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1896', 'WPtitle': 'DNA damage response', 'gene': ['PML', 'PRKDC', 'CDKN1A', 'RAD52', 'BRCA1', 'BID', 'FAS', 'RAD51', 'CASP8', 'SMC1A', 'BAX', 'MRE11', 'MYC', 'NBN', 'PIDD1', 'RFC1', 'ATRIP', 'TP53AIP1', 'TLK2', 'CCNB3', 'HUS1B', 'CHEK1', 'RAD17', 'CASP3', 'CDK1', 'CYCS', 'RAD9A', 'ATR', 'CHEK2', 'H2AX', 'CREB1', 'TNFRSF10B', 'CDK2', 'CASP9', 'CDK4', 'MDM2', 'TP53', 'PMAIP1', 'AKT1', 'FANCD2', 'ATM', 'ABL1', 'CCNE1', 'BBC3', 'CCND1', 'CDKN1B', 'RAD1', 'RAD50', 'RPA2', 'CCND2', 'APAF1', 'RB1', 'CCNE2', 'CCNB2', 'CDC25C', 'CDK5', 'CDK6', 'CCND3', 'GADD45A', 'CCNB1', 'DDB2', 'E2F1', 'GADD45G', 'CDC25A', 'TLK1', 'GADD45B', 'SFN', 'RRM2B', 'SESN1']}, {'KEID': 'https://identifiers.org/aop.events/1896', 'WPtitle': 'DNA repair pathways full network', 'gene': ['FAAP24', 'RFC3', 'PCNA', 'RPA1', 'FANCD2', 'FANCI', 'BRCA2', 'BRIP1', 'CHEK1', 'ATM', 'POLE3', 'WRN', 'RFC4', 'USP1', 'FANCC', 'ATR', 'EXO1', 'POLH', 'CENPX', 'FANCM', 'FANCA', 'FAAP100', 'FANCF', 'FANCB', 'POLE', 'ERCC4', 'POLD4', 'CENPS', 'FANCG', 'FAN1', 'HMGB1', 'H2AX', 'APEX1', 'RBX1', 'XRCC5', 'MLH1', 'PMS2', 'PARP2', 'XPC', 'XRCC4', 'LIG4', 'GTF2H5', 'MNAT1', 'POLB', 'GTF2H3', 'GTF2H1', 'ERCC2', 'RAD23B', 'RAP1A', 'CDK7', 'DDB2', 'CCNH', 'GTF2H2', 'PARP1', 'ERCC3', 'GTF2H4', 'RAD23A', 'LIG3', 'REV3L', 'PNKP', 'ERCC8', 'NTHL1', 'XRCC1', 'UNG', 'MSH2', 'POLI', 'MPG', 'LIG1', 'NEIL3', 'MSH3', 'OGG1', 'MSH6', 'POLM', 'SMUG1', 'MBD4', 'TERF2', 'MUTYH', 'ERCC5', 'REV1', 'XPA', 'TDG', 'CUL4A', 'CETN2', 'DCLRE1C', 'NEIL2', 'CUL4B', 'POLL', 'DDB1', 'FEN1', 'APEX2', 'MGMT', 'NHEJ1', 'XRCC6', 'RAD54B', 'ERCC6', 'PRKDC', 'RAD52', 'BRCA1', 'ERCC1', 'MRE11', 'RFC1', 'RFC2', 'RAD51', 'POLD1', 'POLD3', 'PALB2', 'POLE2', 'NBN', 'RPA3', 'POLD2', 'RAD51C', 'RFC5', 'FANCE', 'RAD50', 'WDR48', 'POLE4', 'FANCL', 'RPA2', 'POLK']}, {'KEID': 'https://identifiers.org/aop.events/1172', 'WPtitle': 'Canonical NF-kB pathway', 'gene': ['NFKB1', 'NFKBIA', 'IKBKB', 'NFKBIE', 'CHUK', 'IKBKG', 'RELA', 'REL']}, {'KEID': 'https://identifiers.org/aop.events/1172', 'WPtitle': 'Interleukin-1 induced activation of NF-kB', 'gene': ['AJUBA', 'SQSTM1', 'TRAF6', 'UBE2N', 'IRAK1', 'UBE2V1', 'NFKB1', 'IL1A', 'PRKCZ', 'TIFA']}, {'KEID': 'https://identifiers.org/aop.events/1496', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1496', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1496', 'WPtitle': 'Cells and molecules involved in local acute inflammatory response', 'gene': ['SELPLG', 'TNF', 'IL6', 'ITGB1', 'CXCL8', 'ITGB2', 'IL1A', 'VCAM1', 'ICAM1', 'C3', 'SELP', 'C5', 'C7', 'C6', 'ITGA4', 'ITGAL', 'KNG1']}, {'KEID': 'https://identifiers.org/aop.events/1496', 'WPtitle': 'Overview of proinflammatory and profibrotic mediators', 'gene': ['IL25', 'IL12A', 'CXCL8', 'IL13', 'CSF1', 'IFNL2', 'IL17D', 'IFNL1', 'IL3', 'CSF2', 'CXCL1', 'CXCL5', 'IL1B', 'IL17C', 'IL17B', 'IL10', 'IL6', 'IFNG', 'IL17A', 'VEGFA', 'IL17F', 'IL23A', 'IL12B', 'IL5', 'IL4', 'CCL20', 'MMP9', 'TGFB1', 'CXCL12', 'CCL2', 'IL2', 'CCL3L1', 'CCL28', 'CTF1', 'IL33', 'CCL1', 'SPP1', 'EPO', 'LIF', 'MMP3', 'PF4', 'PPBP', 'LTA', 'EBI3', 'CSF3', 'CXCL2', 'IL7', 'OSM', 'IL22', 'CCL27', 'IL31', 'CCL15', 'CNTF', 'CXCL11', 'CXCL3', 'IL18', 'CXCL16', 'CXCL13', 'TNFSF13', 'AREG', 'IL1A', 'IL11', 'CCL22', 'TNFSF13B', 'CCL8', 'CXCL9', 'IL21', 'IL9', 'CXCL6', 'CCL21', 'NFKB1', 'CCL26', 'IFNL3', 'TNF', 'CCL5', 'IL26', 'CCL18', 'CCL4L2', 'CCL14', 'IFNW1', 'CCL13', 'IFNK', 'TSLP', 'IL24', 'IL20', 'CCL16', 'CCL23', 'CXCL17', 'IL36RN', 'IL36A', 'IL1F10', 'IL36B', 'XCL2', 'IL37', 'IL36G', 'PF4V1', 'CCL11', 'MMP1', 'IFNB1', 'CXCL10', 'IFNA7', 'CCL3', 'CCL4', 'IL27', 'IFNA14', 'IFNA1', 'IFNA17', 'IFNA13', 'IFNA4', 'IFNA5', 'IFNA16', 'IFNA2', 'IFNA10', 'IL19', 'IL15', 'IFNA6', 'IFNA8', 'IFNA21', 'IL1RN', 'XCL1', 'CXCL14', 'CCL19', 'CCL25', 'CCL7', 'CCL24', 'CX3CL1', 'CCL17']}, {'KEID': 'https://identifiers.org/aop.events/1496', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/68', 'WPtitle': 'Metabolic pathways of fibroblasts', 'gene': ['ALDH18A1', 'UGDH', 'GCK', 'CD36', 'PYCR1', 'PSPH', 'RHOA', 'GLUD1', 'SLC2A1', 'GPI', 'GLS', 'LDHA', 'SLC1A5', 'PSAT1', 'LOXL2', 'UGP2', 'P3H3', 'SLC16A1', 'P4HA3', 'P3H4', 'PHGDH', 'PGM1', 'BMP1', 'P4HA1', 'ADAMTS2', 'FGFR1', 'SERPINH1', 'PLOD1', 'PLCG1', 'FGFR4', 'LPAR1', 'P4HA2']}, {'KEID': 'https://identifiers.org/aop.events/68', 'WPtitle': 'Metabolic pathways of fibroblasts', 'gene': ['ALDH18A1', 'UGDH', 'GCK', 'CD36', 'PYCR1', 'PSPH', 'RHOA', 'GLUD1', 'SLC2A1', 'GPI', 'GLS', 'LDHA', 'SLC1A5', 'PSAT1', 'LOXL2', 'UGP2', 'P3H3', 'SLC16A1', 'P4HA3', 'P3H4', 'PHGDH', 'PGM1', 'BMP1', 'P4HA1', 'ADAMTS2', 'FGFR1', 'SERPINH1', 'PLOD1', 'PLCG1', 'FGFR4', 'LPAR1', 'P4HA2']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Cells and molecules involved in local acute inflammatory response', 'gene': ['SELPLG', 'TNF', 'IL6', 'ITGB1', 'CXCL8', 'ITGB2', 'IL1A', 'VCAM1', 'ICAM1', 'C3', 'SELP', 'C5', 'C7', 'C6', 'ITGA4', 'ITGAL', 'KNG1']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Overview of proinflammatory and profibrotic mediators', 'gene': ['IL25', 'IL12A', 'CXCL8', 'IL13', 'CSF1', 'IFNL2', 'IL17D', 'IFNL1', 'IL3', 'CSF2', 'CXCL1', 'CXCL5', 'IL1B', 'IL17C', 'IL17B', 'IL10', 'IL6', 'IFNG', 'IL17A', 'VEGFA', 'IL17F', 'IL23A', 'IL12B', 'IL5', 'IL4', 'CCL20', 'MMP9', 'TGFB1', 'CXCL12', 'CCL2', 'IL2', 'CCL3L1', 'CCL28', 'CTF1', 'IL33', 'CCL1', 'SPP1', 'EPO', 'LIF', 'MMP3', 'PF4', 'PPBP', 'LTA', 'EBI3', 'CSF3', 'CXCL2', 'IL7', 'OSM', 'IL22', 'CCL27', 'IL31', 'CCL15', 'CNTF', 'CXCL11', 'CXCL3', 'IL18', 'CXCL16', 'CXCL13', 'TNFSF13', 'AREG', 'IL1A', 'IL11', 'CCL22', 'TNFSF13B', 'CCL8', 'CXCL9', 'IL21', 'IL9', 'CXCL6', 'CCL21', 'NFKB1', 'CCL26', 'IFNL3', 'TNF', 'CCL5', 'IL26', 'CCL18', 'CCL4L2', 'CCL14', 'IFNW1', 'CCL13', 'IFNK', 'TSLP', 'IL24', 'IL20', 'CCL16', 'CCL23', 'CXCL17', 'IL36RN', 'IL36A', 'IL1F10', 'IL36B', 'XCL2', 'IL37', 'IL36G', 'PF4V1', 'CCL11', 'MMP1', 'IFNB1', 'CXCL10', 'IFNA7', 'CCL3', 'CCL4', 'IL27', 'IFNA14', 'IFNA1', 'IFNA17', 'IFNA13', 'IFNA4', 'IFNA5', 'IFNA16', 'IFNA2', 'IFNA10', 'IL19', 'IL15', 'IFNA6', 'IFNA8', 'IFNA21', 'IL1RN', 'XCL1', 'CXCL14', 'CCL19', 'CCL25', 'CCL7', 'CCL24', 'CX3CL1', 'CCL17']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Cells and molecules involved in local acute inflammatory response', 'gene': ['SELPLG', 'TNF', 'IL6', 'ITGB1', 'CXCL8', 'ITGB2', 'IL1A', 'VCAM1', 'ICAM1', 'C3', 'SELP', 'C5', 'C7', 'C6', 'ITGA4', 'ITGAL', 'KNG1']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'Overview of proinflammatory and profibrotic mediators', 'gene': ['IL25', 'IL12A', 'CXCL8', 'IL13', 'CSF1', 'IFNL2', 'IL17D', 'IFNL1', 'IL3', 'CSF2', 'CXCL1', 'CXCL5', 'IL1B', 'IL17C', 'IL17B', 'IL10', 'IL6', 'IFNG', 'IL17A', 'VEGFA', 'IL17F', 'IL23A', 'IL12B', 'IL5', 'IL4', 'CCL20', 'MMP9', 'TGFB1', 'CXCL12', 'CCL2', 'IL2', 'CCL3L1', 'CCL28', 'CTF1', 'IL33', 'CCL1', 'SPP1', 'EPO', 'LIF', 'MMP3', 'PF4', 'PPBP', 'LTA', 'EBI3', 'CSF3', 'CXCL2', 'IL7', 'OSM', 'IL22', 'CCL27', 'IL31', 'CCL15', 'CNTF', 'CXCL11', 'CXCL3', 'IL18', 'CXCL16', 'CXCL13', 'TNFSF13', 'AREG', 'IL1A', 'IL11', 'CCL22', 'TNFSF13B', 'CCL8', 'CXCL9', 'IL21', 'IL9', 'CXCL6', 'CCL21', 'NFKB1', 'CCL26', 'IFNL3', 'TNF', 'CCL5', 'IL26', 'CCL18', 'CCL4L2', 'CCL14', 'IFNW1', 'CCL13', 'IFNK', 'TSLP', 'IL24', 'IL20', 'CCL16', 'CCL23', 'CXCL17', 'IL36RN', 'IL36A', 'IL1F10', 'IL36B', 'XCL2', 'IL37', 'IL36G', 'PF4V1', 'CCL11', 'MMP1', 'IFNB1', 'CXCL10', 'IFNA7', 'CCL3', 'CCL4', 'IL27', 'IFNA14', 'IFNA1', 'IFNA17', 'IFNA13', 'IFNA4', 'IFNA5', 'IFNA16', 'IFNA2', 'IFNA10', 'IL19', 'IL15', 'IFNA6', 'IFNA8', 'IFNA21', 'IL1RN', 'XCL1', 'CXCL14', 'CCL19', 'CCL25', 'CCL7', 'CCL24', 'CX3CL1', 'CCL17']}, {'KEID': 'https://identifiers.org/aop.events/1493', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/265', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/265', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/265', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/1492', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1817', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/1817', 'WPtitle': 'Apoptosis modulation and signaling', 'gene': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53']}, {'KEID': 'https://identifiers.org/aop.events/1819', 'WPtitle': 'Interferon-mediated signaling', 'gene': ['IFNAR1', 'IFNAR2', 'IFNA7', 'IFNGR2', 'IFNB1', 'IFNGR1', 'IFNE', 'IFNA14', 'IFNA10', 'IFNA13', 'IFNA1', 'IFNA2', 'IFNA6', 'IFNA8', 'IFNA4', 'IFNA5', 'IFNA21', 'IFNA16', 'IFNA17', 'IFNK', 'IFNW1', 'PRKCA', 'PIK3R1', 'PIK3CA', 'IFNL2', 'IFNL1', 'IFNL3', 'IFNG', 'JAK1', 'IL10RB', 'JAK2', 'IRF9', 'IFNLR1', 'IFNL4', 'TYK2', 'STAT1', 'STAT2']}, {'KEID': 'https://identifiers.org/aop.events/1819', 'WPtitle': 'Type II interferon signaling', 'gene': ['PSMB9', 'ISG15', 'CXCL10', 'NOS2', 'IFNGR1', 'IFNGR2', 'IFI6', 'ICAM1', 'CXCL9', 'PRKCD', 'IFNB1', 'HLA-B', 'CIITA', 'OAS1', 'IFNA2', 'IRF1', 'TAP1', 'REG1A', 'IRF4', 'IRF8', 'IRF2', 'SOCS3', 'STAT1', 'STAT2', 'H4C1', 'SOCS1', 'IFIT2', 'IRF9', 'PTPN11', 'CYBB', 'IL1B', 'IFNG', 'JAK2', 'JAK1', 'SPI1', 'GBP1', 'EIF2AK2']}, {'KEID': 'https://identifiers.org/aop.events/1750', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1750', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1750', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/1750', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/1750', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1901', 'WPtitle': 'Interferon-mediated signaling', 'gene': ['IFNAR1', 'IFNAR2', 'IFNA7', 'IFNGR2', 'IFNB1', 'IFNGR1', 'IFNE', 'IFNA14', 'IFNA10', 'IFNA13', 'IFNA1', 'IFNA2', 'IFNA6', 'IFNA8', 'IFNA4', 'IFNA5', 'IFNA21', 'IFNA16', 'IFNA17', 'IFNK', 'IFNW1', 'PRKCA', 'PIK3R1', 'PIK3CA', 'IFNL2', 'IFNL1', 'IFNL3', 'IFNG', 'JAK1', 'IL10RB', 'JAK2', 'IRF9', 'IFNLR1', 'IFNL4', 'TYK2', 'STAT1', 'STAT2']}, {'KEID': 'https://identifiers.org/aop.events/1848', 'WPtitle': 'TLR4 signaling and tolerance', 'gene': ['TRAM1', 'TIRAP', 'TLR4', 'IL6', 'IRF3', 'TRAF3', 'NFKB1', 'TAB2', 'TAB1', 'MYD88', 'TRAF6', 'RIPK1', 'IKBKE', 'CXCL8', 'NFKBIA', 'TICAM1', 'IKBKG', 'IRAK3', 'TNF', 'CHUK', 'IKBKB', 'MAP3K7', 'IRAK4', 'IRAK1', 'TBK1', 'IRF7', 'INPP5D', 'IFNB1']}, {'KEID': 'https://identifiers.org/aop.events/1848', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1848', 'WPtitle': 'Toll-like receptor signaling related to MyD88', 'gene': ['TICAM1', 'TLR2', 'TRAF3', 'TLR4', 'IRF3', 'IKBKB', 'MAPK1', 'NFKB1', 'TOLLIP', 'TIRAP', 'TLR9', 'TICAM2', 'IKBKE', 'IKBKG', 'CHUK', 'TRAF6', 'TBK1', 'TLR6', 'TLR1', 'TLR7', 'IRAK4', 'IRF7', 'IRAK1', 'MYD88', 'TLR8', 'NFKB2', 'TLR3', 'TLR5', 'REL', 'RELB', 'RELA']}, {'KEID': 'https://identifiers.org/aop.events/1847', 'WPtitle': 'SARS-CoV-2 replication organelle formation', 'gene': ['PIK3R4', 'AMBRA1', 'BECN1', 'PIK3C3', 'ZFYVE1', 'ATG14']}, {'KEID': 'https://identifiers.org/aop.events/1748', 'WPtitle': 'Downregulation of ACE2 by SARS-CoV-2 spike protein', 'gene': ['ACE', 'AGTR1', 'AGTR2', 'ACE2']}, {'KEID': 'https://identifiers.org/aop.events/1365', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/1365', 'WPtitle': 'Apoptosis modulation and signaling', 'gene': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53']}, {'KEID': 'https://identifiers.org/aop.events/1851', 'WPtitle': 'Angiotensin II receptor type 1 pathway (Homo sapiens)'}, {'KEID': 'https://identifiers.org/aop.events/889', 'WPtitle': 'Cellular Proteostasis'}, {'KEID': 'https://identifiers.org/aop.events/890', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/1587', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1587', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1457', 'WPtitle': 'TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition', 'gene': ['AKT1', 'VIM', 'CDH1', 'MAPK3', 'TNC', 'SMAD2', 'SMAD3', 'ID1', 'CDH2', 'SNAI2', 'CDH16', 'CDH6', 'MAPK1', 'SNAI1', 'SMAD4', 'RUNX2', 'FN1']}, {'KEID': 'https://identifiers.org/aop.events/1586', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/149', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1575', 'WPtitle': 'Apoptosis modulation and signaling', 'gene': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53']}, {'KEID': 'https://identifiers.org/aop.events/1575', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/1548', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1576', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1579', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1579', 'WPtitle': 'Complement activation', 'gene': ['C4A', 'C1QC', 'C1QA', 'C1QB', 'CFP', 'C1R', 'MASP2', 'CD55', 'CFD', 'MASP1', 'CFB', 'C1S', 'C2', 'C3', 'C7', 'C8A', 'C8G', 'C9', 'C4B', 'C5', 'C6', 'C8B']}, {'KEID': 'https://identifiers.org/aop.events/1579', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1579', 'WPtitle': 'TNF-alpha signaling', 'gene': ['RFK', 'NFKBIE', 'NFKBIB', 'NSMAF', 'PTPRCAP', 'CHUK', 'RIPK3', 'TAB1', 'TRAP1', 'TANK', 'AKT1', 'CYBA', 'CSNK2A1', 'CREBBP', 'MAP3K8', 'RFFL', 'TBK1', 'TAB3', 'TAB2', 'IKBKB', 'HSP90AA1', 'BIRC3', 'BIRC2', 'HRAS', 'APAF1', 'IL6', 'MAP3K3', 'JUN', 'MAP3K1', 'NRAS', 'NFKBIA', 'NFKB1', 'MAP3K5', 'MAPK8', 'MAPK3', 'MAPK1', 'PPP2CA', 'BAD', 'DIABLO', 'MAP2K7', 'MAP2K6', 'MAP2K3', 'MAPK9', 'BCL2L1', 'RAF1', 'RAC1', 'MAP4K2', 'BAX', 'SOS1', 'MAP2K4', 'BID', 'CCL2', 'TNF', 'MAP3K7', 'TRADD', 'MADD', 'IKBKG', 'CASP9', 'CASP8', 'CASP7', 'CASP3', 'TNFRSF1B', 'TNFRSF1A', 'CFLAR', 'MAP3K14', 'FADD', 'RIPK1', 'NOXO1', 'GLUL', 'SMPD2', 'CDC37', 'GRB2', 'KSR2', 'PLK1', 'NFKB2', 'KRAS', 'SKP1', 'REL', 'PSMD2', 'OTUD7B', 'PRKCZ', 'CUL1', 'TXN', 'TRAF2', 'TRAF1', 'TNFAIP3', 'BTRC', 'KSR1', 'FBXW11', 'NOX1', 'SELE', 'PYGL']}, {'KEID': 'https://identifiers.org/aop.events/87', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/87', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/87', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/87', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/249', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/249', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/288', 'WPtitle': 'Farnesoid X receptor pathway', 'gene': ['UGT2B4', 'IRS2', 'SLC27A5', 'CYP8B1', 'IP6K3', 'ABCB4', 'NR0B2', 'SULT2A1', 'NR1H4', 'FGF19', 'BAAT', 'SLC10A1', 'ABCB11', 'SLCO2B1', 'RXRA', 'CYP7A1', 'CYP3A4', 'PPARGC1A', 'FKBP5']}, {'KEID': 'https://identifiers.org/aop.events/288', 'WPtitle': 'Pregnane X receptor pathway', 'gene': ['UGT1A9', 'ABCC2', 'CYP4F12', 'NCOA3', 'PPARGC1A', 'HSP90AA1', 'NCOA1', 'CYP2B6', 'RXRA', 'SRC', 'NRIP1', 'FOXO1', 'CYP3A4', 'NCOA2', 'UGT1A4', 'CYP2A6', 'ABCC4', 'SLCO1B1', 'ABCC3', 'PSMC5', 'ABCB1', 'CYP2C9', 'GSTA2', 'UGT1A1', 'UGT1A6', 'DNAJC7', 'CYP3A7', 'SRPX2', 'CYP3A5', 'CYP2C19', 'NR1I2', 'SULT2A1']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'Glutathione metabolism', 'gene': ['GPX4', 'IDH1', 'GGT1', 'G6PD', 'GPX1', 'GPX2', 'GPX3', 'GSTA5', 'GCLM', 'GSR', 'GSTT2', 'GSTA1', 'GSTM1', 'GCLC', 'GSTM2', 'GGT5', 'OPLAH', 'ANPEP', 'GSS']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'Wnt signaling', 'gene': ['SERPINF1', 'MAP3K7', 'CAMK2D', 'PPP3CA', 'SOST', 'PRKCB', 'CSNK2B', 'CTNNB1', 'GSK3B', 'WNT5A', 'CCND1', 'RAC1', 'PRKCA', 'WNT16', 'MYC', 'LRP5', 'RHOA', 'JUN', 'WNT1', 'NFATC3', 'CCND2', 'AXIN1', 'WNT10B', 'PLCB4', 'TCF7', 'CSNK1A1', 'PLCB2', 'ROCK2', 'TCF7L1', 'PLCB3', 'TCF7L2', 'CAMK2G', 'LEF1', 'FZD10', 'CCND3', 'DAAM1', 'NFATC2', 'CTBP1', 'CTBP2', 'PLCB1', 'WNT2', 'PRKCG', 'WNT4', 'PLAU', 'LRP6', 'APC', 'FZD2', 'DVL3', 'DVL2', 'DVL1', 'WNT5B', 'WNT10A', 'FZD3', 'FZD5', 'WNT2B', 'WNT11', 'WNT7B', 'WNT7A', 'WNT6', 'WNT3', 'WNT3A', 'FZD9', 'FZD8', 'FZD7', 'FZD6', 'FZD1', 'GPC4', 'NLK', 'CHD8', 'NFATC4', 'PORCN', 'SFRP1', 'DKK4', 'SFRP4', 'PPP3CB', 'INVS', 'SFRP5', 'PPP3CC', 'PRICKLE1', 'NKD1', 'SFRP2', 'NKD2', 'DAAM2', 'CER1', 'DKK2', 'WIF1', 'VANGL2', 'PRICKLE2', 'SENP2', 'SOX17', 'CXXC4', 'VANGL1', 'CTNNBIP1', 'FRAT2', 'NOTUM', 'PPP3R2', 'PPP3R1', 'CSNK2A3', 'FRAT1', 'CSNK1E', 'ROR1', 'ROR2', 'RYK', 'FOSL1', 'KREMEN1', 'MAPK9', 'CAMK2B', 'CSNK2A2', 'CAMK2A', 'CSNK2A1', 'MAPK8', 'DKK1', 'NFATC1']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'p53 transcriptional gene network', 'gene': ['PRKAB2', 'PRKAA1', 'PCNA', 'GLS2', 'CDK2', 'POLK', 'CCNG1', 'PRKAB1', 'NCF2', 'PRKAG3', 'FASLG', 'SLC2A1', 'TNFRSF10B', 'APAF1', 'CCL2', 'TSC2', 'CCNE1', 'BBC3', 'BAX', 'PRKAG2', 'ULBP1', 'CDKN1A', 'FAS', 'TIGAR', 'MTOR', 'MSH2', 'CX3CL1', 'ERCC5', 'PML', 'MGMT', 'ACAD11', 'PRKAA2', 'MLST8', 'POLH', 'ADORA2B', 'TNFRSF10D', 'FANCC', 'THBS1', 'PMAIP1', 'RPTOR', 'NOTCH1', 'SERPINE1', 'AURKA', 'LIF', 'MIR34B', 'MIR34C', 'MIR34A', 'GADD45A', 'TP53I3', 'XPC', 'SLC7A11', 'BTG2', 'CDC25C', 'TP53AIP1', 'ULBP2', 'SAT1', 'MLH1', 'ICAM1', 'XRCC5', 'ULK1', 'PRKAG1', 'PIDD1', 'IRF9', 'MIR145', 'TNF', 'GPX1', 'AKT1S1', 'DDB2', 'DEPTOR', 'PTEN', 'DDIT4', 'ISG15', 'RRM2B', 'SESN1', 'CDC25A', 'ULK2', 'IRF5', 'NANOG', 'MIR200C', 'SESN2', 'SCO2', 'SFN', 'FUCA1', 'SIVA1', 'ADGRB1', 'SERPINB5', 'PERP', 'TRAF4', 'ALDH4A1', 'DRAM1', 'E2F7', 'TP53INP1', 'SMR3B', 'CPT1C', 'RPRM', 'ZMAT3']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'PPAR signaling', 'gene': ['ACAA1', 'ACOX3', 'ACSL4', 'NR1H3', 'SCD', 'CPT1B', 'SLC27A6', 'FABP1', 'DBI', 'ACSBG1', 'HMGCS2', 'APOA5', 'ADIPOQ', 'ACSL1', 'LPL', 'CYP7A1', 'CD36', 'PDPK1', 'FADS2', 'RXRA', 'PCK1', 'CYP4A11', 'APOA2', 'ACSBG2', 'PPARD', 'ME1', 'ACADL', 'EHHADH', 'ACSL3', 'PLTP', 'PCK2', 'ILK', 'AQP7', 'ACOX2', 'PLIN1', 'FABP6', 'PPARA', 'CYP8B1', 'MMP1', 'UCP1', 'ACADM', 'APOA1', 'PPARG', 'CYP27A1', 'SLC27A2', 'SLC27A5', 'GK3P', 'FABP5', 'OLR1', 'APOC3', 'CPT1A', 'RXRB', 'RXRG', 'SLC27A4', 'FABP4', 'ACOX1', 'FABP2', 'ANGPTL4', 'ACSL6', 'ACSL5', 'CPT2', 'GK2', 'SCP2', 'SLC27A1', 'FABP3', 'SORBS1', 'CPT1C', 'FABP7']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'NRF2 pathway', 'gene': ['SLC6A20', 'SLC6A18', 'FTH1', 'GSTM4', 'SLC39A2', 'SLC39A13', 'SLC6A5', 'SLC5A10', 'SLC7A11', 'SLC2A13', 'SLC6A1', 'CBR3', 'CES5A', 'SLC5A11', 'CBR1', 'SLC2A6', 'SLC39A3', 'SLC2A5', 'MGST3', 'SLC39A6', 'SLC39A1', 'SLC2A12', 'SLC39A4', 'SLC39A12', 'SLC5A12', 'GSTA5', 'GPX2', 'ADH7', 'SLC6A9', 'MAFF', 'CYP4A11', 'GSTA4', 'SLC6A19', 'GSTA3', 'CES3', 'CES2', 'SLC2A14', 'CES4A', 'GCLC', 'UGT1A7', 'UGT1A4', 'CYP2A6', 'SLC5A8', 'SLC6A14', 'SRXN1', 'MAFG', 'SLC6A17', 'SLC2A7', 'SLC39A10', 'SLC2A10', 'TXNRD3', 'CES1', 'AGER', 'TXNRD1', 'SLC5A3', 'GPX3', 'SLC2A3', 'HGF', 'HMOX1', 'PDGFB', 'KEAP1', 'SERPINA1', 'UGT1A1', 'GSTA1', 'GSTA2', 'GSTM2', 'TGFBR2', 'SLC2A2', 'UGT1A6', 'UGT2B7', 'NQO1', 'FGF13', 'GSTM1', 'EPHA2', 'TXN', 'NRG1', 'SLC5A5', 'ABCC3', 'NFE2L2', 'ABCC4', 'HSP90AA1', 'HSP90AB1', 'TGFB2', 'UGT1A9', 'ABCC2', 'RXRA', 'SLC2A4', 'HSPA1A', 'G6PD', 'PGD', 'SLC6A3', 'TGFA', 'SQSTM1', 'SLC2A1', 'SLC5A7', 'HBEGF', 'TGFB1', 'SLC6A2', 'SLC39A14', 'GSR', 'SLC5A1', 'GGT1', 'GSTT2', 'SLC5A4', 'BLVRB', 'SLC39A9', 'EPHA3', 'SLC6A16', 'ME1', 'SLC6A15', 'SLC6A7', 'SLC6A13', 'GCLM', 'MGST2', 'GSTP1', 'FTL', 'SLC39A8', 'SLC5A6', 'SLC2A8', 'SLC5A2', 'SLC39A5', 'SLC6A6', 'SLC6A8', 'SLC6A11', 'DNAJB1', 'SLC2A11', 'SLC39A11', 'GSTM3', 'GSTM5', 'SLC5A9', 'PRDX6', 'PRDX1', 'EGR1', 'SLC2A9', 'SOD3', 'ALDH3A1', 'SLC6A4', 'PTGR1', 'ABCC5', 'SLC39A7', 'PPARD']}, {'KEID': 'https://identifiers.org/aop.events/209', 'WPtitle': 'DNA repair pathways full network', 'gene': ['FAAP24', 'RFC3', 'PCNA', 'RPA1', 'FANCD2', 'FANCI', 'BRCA2', 'BRIP1', 'CHEK1', 'ATM', 'POLE3', 'WRN', 'RFC4', 'USP1', 'FANCC', 'ATR', 'EXO1', 'POLH', 'CENPX', 'FANCM', 'FANCA', 'FAAP100', 'FANCF', 'FANCB', 'POLE', 'ERCC4', 'POLD4', 'CENPS', 'FANCG', 'FAN1', 'HMGB1', 'H2AX', 'APEX1', 'RBX1', 'XRCC5', 'MLH1', 'PMS2', 'PARP2', 'XPC', 'XRCC4', 'LIG4', 'GTF2H5', 'MNAT1', 'POLB', 'GTF2H3', 'GTF2H1', 'ERCC2', 'RAD23B', 'RAP1A', 'CDK7', 'DDB2', 'CCNH', 'GTF2H2', 'PARP1', 'ERCC3', 'GTF2H4', 'RAD23A', 'LIG3', 'REV3L', 'PNKP', 'ERCC8', 'NTHL1', 'XRCC1', 'UNG', 'MSH2', 'POLI', 'MPG', 'LIG1', 'NEIL3', 'MSH3', 'OGG1', 'MSH6', 'POLM', 'SMUG1', 'MBD4', 'TERF2', 'MUTYH', 'ERCC5', 'REV1', 'XPA', 'TDG', 'CUL4A', 'CETN2', 'DCLRE1C', 'NEIL2', 'CUL4B', 'POLL', 'DDB1', 'FEN1', 'APEX2', 'MGMT', 'NHEJ1', 'XRCC6', 'RAD54B', 'ERCC6', 'PRKDC', 'RAD52', 'BRCA1', 'ERCC1', 'MRE11', 'RFC1', 'RFC2', 'RAD51', 'POLD1', 'POLD3', 'PALB2', 'POLE2', 'NBN', 'RPA3', 'POLD2', 'RAD51C', 'RFC5', 'FANCE', 'RAD50', 'WDR48', 'POLE4', 'FANCL', 'RPA2', 'POLK']}, {'KEID': 'https://identifiers.org/aop.events/1275', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1498', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/1498', 'WPtitle': 'Type II interferon signaling', 'gene': ['PSMB9', 'ISG15', 'CXCL10', 'NOS2', 'IFNGR1', 'IFNGR2', 'IFI6', 'ICAM1', 'CXCL9', 'PRKCD', 'IFNB1', 'HLA-B', 'CIITA', 'OAS1', 'IFNA2', 'IRF1', 'TAP1', 'REG1A', 'IRF4', 'IRF8', 'IRF2', 'SOCS3', 'STAT1', 'STAT2', 'H4C1', 'SOCS1', 'IFIT2', 'IRF9', 'PTPN11', 'CYBB', 'IL1B', 'IFNG', 'JAK2', 'JAK1', 'SPI1', 'GBP1', 'EIF2AK2']}, {'KEID': 'https://identifiers.org/aop.events/1498', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1498', 'WPtitle': 'Overview of proinflammatory and profibrotic mediators', 'gene': ['IL25', 'IL12A', 'CXCL8', 'IL13', 'CSF1', 'IFNL2', 'IL17D', 'IFNL1', 'IL3', 'CSF2', 'CXCL1', 'CXCL5', 'IL1B', 'IL17C', 'IL17B', 'IL10', 'IL6', 'IFNG', 'IL17A', 'VEGFA', 'IL17F', 'IL23A', 'IL12B', 'IL5', 'IL4', 'CCL20', 'MMP9', 'TGFB1', 'CXCL12', 'CCL2', 'IL2', 'CCL3L1', 'CCL28', 'CTF1', 'IL33', 'CCL1', 'SPP1', 'EPO', 'LIF', 'MMP3', 'PF4', 'PPBP', 'LTA', 'EBI3', 'CSF3', 'CXCL2', 'IL7', 'OSM', 'IL22', 'CCL27', 'IL31', 'CCL15', 'CNTF', 'CXCL11', 'CXCL3', 'IL18', 'CXCL16', 'CXCL13', 'TNFSF13', 'AREG', 'IL1A', 'IL11', 'CCL22', 'TNFSF13B', 'CCL8', 'CXCL9', 'IL21', 'IL9', 'CXCL6', 'CCL21', 'NFKB1', 'CCL26', 'IFNL3', 'TNF', 'CCL5', 'IL26', 'CCL18', 'CCL4L2', 'CCL14', 'IFNW1', 'CCL13', 'IFNK', 'TSLP', 'IL24', 'IL20', 'CCL16', 'CCL23', 'CXCL17', 'IL36RN', 'IL36A', 'IL1F10', 'IL36B', 'XCL2', 'IL37', 'IL36G', 'PF4V1', 'CCL11', 'MMP1', 'IFNB1', 'CXCL10', 'IFNA7', 'CCL3', 'CCL4', 'IL27', 'IFNA14', 'IFNA1', 'IFNA17', 'IFNA13', 'IFNA4', 'IFNA5', 'IFNA16', 'IFNA2', 'IFNA10', 'IL19', 'IL15', 'IFNA6', 'IFNA8', 'IFNA21', 'IL1RN', 'XCL1', 'CXCL14', 'CCL19', 'CCL25', 'CCL7', 'CCL24', 'CX3CL1', 'CCL17']}, {'KEID': 'https://identifiers.org/aop.events/1499', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1500', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/1500', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1500', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1032', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1089', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1488', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/1488', 'WPtitle': 'GPCRs class C metabotropic glutamate pheromone', 'gene': ['GRM3', 'GPRC5B', 'GPRC5C', 'GPRC5A', 'GRM1', 'GRM2', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GABBR2', 'GRM6', 'CASR', 'GPRC5D', 'GABBR1']}, {'KEID': 'https://identifiers.org/aop.events/1494', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1494', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1494', 'WPtitle': 'Cells and molecules involved in local acute inflammatory response', 'gene': ['SELPLG', 'TNF', 'IL6', 'ITGB1', 'CXCL8', 'ITGB2', 'IL1A', 'VCAM1', 'ICAM1', 'C3', 'SELP', 'C5', 'C7', 'C6', 'ITGA4', 'ITGAL', 'KNG1']}, {'KEID': 'https://identifiers.org/aop.events/52', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/52', 'WPtitle': 'Phosphatidyl inositol phosphate pathway', 'gene': ['MTMR6', 'MTMR8', 'PI4K2A', 'PI4K2B', 'TPTE2', 'INPP4B', 'PLCB4', 'PLCB3', 'PLCB2', 'PI4KB', 'PIP5K1C', 'INPP5E', 'PLCD4', 'PIK3C2A', 'PIK3CD', 'PIK3CG', 'PIK3CB', 'PIK3CA', 'PLCG2', 'PIK3C2G', 'INPP4A', 'PI4KA', 'PLCD3', 'PLCD1', 'PIKFYVE', 'SACM1L', 'PIP5K1A', 'INPP5D', 'FIG4', 'PIP4K2C', 'MTMR1', 'MTM1', 'OCRL', 'PIP4K2B', 'PIP4K2A', 'PIP5K1B', 'PIP4P2', 'PIP4P1', 'MTMR2', 'PLCE1', 'PLCB1', 'PIK3C2B', 'INPP5K', 'PTEN', 'PLCG1', 'IPMK']}, {'KEID': 'https://identifiers.org/aop.events/52', 'WPtitle': 'GPCRs, class C metabotropic glutamate pheromone'}, {'KEID': 'https://identifiers.org/aop.events/381', 'WPtitle': 'BDNF-TrkB signaling', 'gene': ['EIF4EBP1', 'EEF2K', 'MTOR', 'MKNK1', 'DLG4', 'TRPC6', 'TRPC3', 'TSC2', 'MAPK1', 'PIK3CG', 'RHEB', 'RPS6KB1', 'RPS6KA1', 'CREB1', 'SOS1', 'SHC1', 'AKT1', 'HRAS', 'BDNF', 'TSC1', 'MAP2K1', 'NRAS', 'ARC', 'GAB1', 'GAB2', 'KRAS', 'NTRK2', 'PLCG1', 'ADCY1', 'GRIN1', 'GRB2', 'BRAF', 'HOMER1']}, {'KEID': 'https://identifiers.org/aop.events/381', 'WPtitle': 'Brain-derived neurotrophic factor (BDNF) signaling', 'gene': ['CREB1', 'CHUK', 'MAPK14', 'CTNNB1', 'CSNK2A1', 'VAV3', 'BCL2L11', 'MAP3K2', 'EIF4EBP1', 'MTOR', 'MAPT', 'ALPL', 'NFATC4', 'PTPRF', 'NTF3', 'GRIP1', 'PTK2B', 'DLG1', 'PRKAA2', 'PIK3R1', 'SHC3', 'PIK3R2', 'PRKAA1', 'PPP2CA', 'MAP3K1', 'NCAM1', 'JAK2', 'JUN', 'MEF2C', 'MEF2A', 'PDPK1', 'NCF2', 'NFKB1', 'NGF', 'NFKBIA', 'AKT1', 'FOXO3', 'FOS', 'EIF4E', 'ELK1', 'IKBKB', 'IRS1', 'SHC2', 'GSK3B', 'HRAS', 'FRS2', 'CFL1', 'VAV2', 'CAMK2A', 'CAMK4', 'SYN1', 'STAT3', 'TSC2', 'TRAF6', 'IRS2', 'SQSTM1', 'RPS6KA5', 'IKBKG', 'CASP3', 'RPS6', 'RPS6KA1', 'RPS6KA3', 'BDNF', 'RPS6KB1', 'RAF1', 'NCF1', 'SRC', 'STAT1', 'BMP2', 'SHC1', 'BAD', 'MAPK10', 'MAPK9', 'MAP2K1', 'MAP2K2', 'MAP2K5', 'PTPN11', 'RAB3A', 'RAC1', 'MAPK8', 'MAPK1', 'MAPK7', 'MAPK3', 'DOK5', 'PRKCD', 'NSF', 'CDK5R1', 'NCK2', 'MARCKS', 'EIF2S2', 'DOCK3', 'DPYSL2', 'SH2B1', 'CDKL5', 'RANBP9', 'GRIA3', 'GRIA2', 'YBX1', 'CDH2', 'CDK5', 'EGR1', 'SIRPA', 'EIF2S1', 'EEF2', 'CNR1', 'EGR2', 'NTRK3', 'RACK1', 'FRS3', 'LINGO1', 'KCNA3', 'CDC42', 'CRTC1', 'IGF2BP1', 'RHOG', 'CAMK1', 'KSR1', 'SH2B2', 'GABRB3', 'CYFIP1', 'ACACB', 'KCNN2', 'SPP1', 'KIDINS220', 'RASGRF1', 'RAP1A', 'RELA', 'SORT1', 'STAT5B', 'ADAM17', 'TIAM1', 'STAT5A', 'APC', 'SHC4', 'FYN', 'GRIA1', 'GRB2', 'GRIN2B', 'GRIN1', 'NGFR', 'NCK1', 'NTRK1', 'PLCG1', 'NTRK2']}, {'KEID': 'https://identifiers.org/aop.events/484', 'WPtitle': 'PI3K-Akt signaling', 'gene': ['NFKB1', 'COL1A1', 'VTN', 'COMP', 'PIK3CG', 'FGF8', 'RPS6KB1', 'ITGB8', 'RHEB', 'PPP2CA', 'VEGFA', 'IL4', 'CCND1', 'CDKN1B', 'IL2', 'COL9A1', 'GNB3', 'PKN1', 'CD19', 'BAD', 'CDKN1A', 'BRCA1', 'IGF1', 'COL9A2', 'GNB5', 'IL4R', 'PIK3CB', 'LAMC2', 'HSP90AA1', 'GSK3B', 'PPP2R5C', 'GNB1', 'EIF4EBP1', 'MTOR', 'SGK3', 'SGK2', 'NTF3', 'NTF4', 'LAMB1', 'ITGA6', 'ITGB5', 'JAK2', 'MAPK1', 'COL9A3', 'HSP90AB1', 'IL2RB', 'SOS2', 'TSC2', 'IKBKB', 'MAPK3', 'CCNE1', 'AKT2', 'PPP2CB', 'GYS1', 'PPP2R1A', 'PIK3R2', 'BDNF', 'F2R', 'RPS6KB2', 'GNG7', 'CSF1', 'GNG12', 'GNG5', 'HRAS', 'VEGFB', 'IKBKG', 'PIK3R6', 'GNG2', 'NRAS', 'INS', 'ITGB3', 'CHUK', 'GNG10', 'TGFA', 'IL3', 'VEGFD', 'TSC1', 'COL1A2', 'SYK', 'MLST8', 'GNG4', 'GNGT2', 'GNG8', 'IRS1', 'THBS3', 'MAP2K1', 'PIK3CD', 'BCL2', 'INSR', 'BCL2L1', 'GNB2', 'LAMB2', 'PRL', 'TP53', 'RPTOR', 'ITGB7', 'PDPK1', 'MCL1', 'PIK3R1', 'AKT1', 'EGFR', 'IL2RG', 'ITGB1', 'EIF4E', 'VEGFC', 'GNG3', 'PRKAA2', 'BCL2L11', 'PRKCA', 'JAK1', 'GNGT1', 'LAMA5', 'PRKAA1', 'ITGB4', 'G6PC1', 'RAF1', 'IL2RA', 'CDK4', 'CASP9', 'NGF', 'LAMC1', 'RAC1', 'MDM2', 'MYC', 'RPS6', 'IL6', 'TLR4', 'THBS1', 'TLR2', 'PPP2R1B', 'CREB1', 'MYB', 'FN1', 'SOS1', 'GNB4', 'ITGB6', 'PIK3R3', 'FASLG', 'ATF2', 'AKT3', 'SGK1', 'GNG11', 'CCND2', 'PIK3CA', 'FOXO3', 'MAP2K2', 'GNG13', 'CDK2', 'PCK1', 'THBS4', 'PRLR', 'VWF', 'FGF6', 'CREB3', 'CSF3', 'LAMA4', 'GHR', 'GYS2', 'PPP2R5D', 'FGF1', 'CSF3R', 'ITGA4', 'PDGFRB', 'FGF12', 'SPP1', 'FGF23', 'TNR', 'STK11', 'PDGFB', 'TCL1A', 'EFNA2', 'OSM', 'COL4A4', 'PHLPP1', 'PPP2R3C', 'FLT3LG', 'ANGPT2', 'MET', 'FGF21', 'JAK3', 'LAMA1', 'FGF14', 'ANGPT4', 'IL7', 'CDC37', 'FGF9', 'FLT1', 'NGFR', 'LPAR2', 'CREB3L3', 'EIF4B', 'PPP2R5A', 'FGFR2', 'LAMC3', 'LAMA3', 'TNC', 'KITLG', 'FGFR1', 'ITGA8', 'PPP2R2C', 'FGF4', 'FGF20', 'FGFR3', 'FGF22', 'PPP2R3A', 'PPP2R5B', 'FGF10', 'ITGA3', 'ITGA2B', 'FLT4', 'PHLPP2', 'HGF', 'IBSP', 'PCK2', 'CCND3', 'CCNE2', 'CDK6', 'PPP2R2A', 'RELA', 'ATF6B', 'NTRK1', 'TCL1B', 'RELN', 'LAMA2', 'COL4A1', 'COL4A6', 'LPAR1', 'LAMB3', 'PDGFA', 'EFNA4', 'GH1', 'ITGA1', 'IFNA7', 'PTEN', 'PPP2R2D', 'LPAR3', 'IFNB1', 'EIF4E1B', 'CHRM1', 'PTK2', 'PDGFD', 'IL7R', 'EFNA1', 'FGF3', 'EPOR', 'IL3RA', 'THBS2', 'GRB2', 'CHRM2', 'EFNA5', 'LPAR5', 'CREB3L2', 'CSF1R', 'KIT', 'CREB3L1', 'FGF18', 'PPP2R2B', 'THEM4', 'FGF17', 'IFNAR2', 'PPP2R5E', 'ANGPT1', 'NTRK2', 'NOS3', 'HSP90B1', 'FGF19', 'ITGA2', 'DDIT4', 'TNXB', 'ITGA5', 'FGF11', 'IL6R', 'FGFR4', 'COL2A1', 'LPAR6', 'FGF2', 'EGF', 'PIK3R5', 'COL6A1', 'FGF7', 'IGF1R', 'IFNAR1', 'COL6A2', 'EPHA2', 'EFNA3', 'ITGA10', 'CREB3L4', 'OSMR', 'CREB5', 'ITGA9', 'PDGFC', 'LPAR4', 'PGF', 'TEK', 'FLT3', 'KDR', 'TNN', 'EPO', 'ATF4', 'FGF13', 'PDGFRA', 'COL4A2', 'KRAS', 'CHAD', 'CSH1', 'ITGA7', 'EIF4E2', 'FGF5', 'ITGA11', 'ITGAV', 'COL4A3', 'COL4A5', 'CSH2', 'PIK3AP1', 'PKN3', 'G6PC3', 'G6PC2', 'PKN2', 'LAMB4', 'IFNA21', 'IFNA5', 'IFNA6', 'IFNA8', 'IFNA16', 'PPP2R3B', 'IFNA17', 'IFNA4', 'IFNA14', 'IFNA13', 'IFNA2', 'IFNA1', 'IFNA10', 'RBL2', 'GH2', 'IGF2', 'COL6A6', 'COL6A3', 'COL6A5']}, {'KEID': 'https://identifiers.org/aop.events/484', 'WPtitle': 'Focal adhesion: PI3K-Akt-mTOR-signaling', 'gene': ['MTOR', 'EIF4EBP1', 'ITGB8', 'PIK3CG', 'COMP', 'PIK3R2', 'PPP2R1A', 'RHEB', 'JAK2', 'HSP90AB1', 'ITGA6', 'HIF1A', 'IL2RB', 'MAPK1', 'GYS1', 'PPP2CB', 'IKBKB', 'TSC2', 'MAPK3', 'AKT2', 'LAMC2', 'PIK3CB', 'GNB1', 'PPP2R5C', 'IL4R', 'SREBF1', 'ITGB5', 'GSK3B', 'HSP90AA1', 'LAMB1', 'IGF1', 'PIK3C2A', 'BAD', 'CDKN1A', 'TSC1', 'VEGFD', 'COL1A2', 'JAK1', 'PRKAA2', 'GNG8', 'GNGT2', 'RPTOR', 'EGFR', 'PIK3R1', 'AKT1', 'EIF4E', 'FOXO1', 'VEGFC', 'ITGB1', 'IL2RG', 'GNG3', 'ITGB2', 'CASP9', 'ITGB4', 'LAMC1', 'MDM2', 'IL2RA', 'NGF', 'IRS4', 'THBS1', 'PPP2R1B', 'RPS6', 'PDPK1', 'ITGB7', 'PIK3CA', 'FOXO3', 'GNG11', 'GNG13', 'PRKAA1', 'RAF1', 'LAMA5', 'FOXA1', 'GNGT1', 'MAP2K2', 'ITGB6', 'GNB4', 'PPP2CA', 'VEGFA', 'GNB3', 'CDKN1B', 'PPARGC1A', 'IL2', 'CREB1', 'SLC2A1', 'AKT3', 'EPAS1', 'ATF2', 'SOS1', 'FN1', 'VTN', 'COL1A1', 'RPS6KB1', 'FGF8', 'COL3A1', 'GNG4', 'MLST8', 'IKBKG', 'ITGB3', 'INS', 'GNG10', 'NRAS', 'ULK1', 'GNG7', 'RPS6KB2', 'HRAS', 'GNG5', 'SLC2A4', 'PIK3R4', 'GNG2', 'IRS2', 'CSF1', 'F2R', 'INSR', 'THBS3', 'IRS1', 'MAP2K1', 'VEGFB', 'GNG12', 'GNB2', 'PRL', 'LAMB2', 'PIK3CD', 'FGF4', 'PPP2R2C', 'PPP2R3A', 'FGF22', 'FGF10', 'ITGAE', 'PHLPP1', 'COL4A4', 'COL5A3', 'LIPE', 'FGF20', 'ITGA8', 'FGFR1', 'COL11A1', 'CREB3L3', 'SLC2A3', 'LAMA3', 'LAMC3', 'KITLG', 'TNC', 'PHLPP2', 'EIF4B', 'FLT4', 'PPP2R5B', 'FGFR3', 'FGFR2', 'ELAVL1', 'PPP2R5A', 'TBC1D1', 'LPAR2', 'NGFR', 'NOS2', 'ITGA2B', 'ITGA3', 'ITGAL', 'IBSP', 'HGF', 'CDC37', 'RAB2A', 'CREB3', 'MET', 'JAK3', 'FGF21', 'CSF3', 'GYS2', 'FGF6', 'VWF', 'ITGA10', 'EPHA2', 'COL6A2', 'IFNAR1', 'PIK3R5', 'ITGAX', 'IGF1R', 'FGF7', 'LPAR6', 'ANGPT1', 'PPP2R5E', 'PELO', 'LPAR4', 'CREB5', 'OSMR', 'PDGFC', 'ITGA9', 'EFNA3', 'CREB3L4', 'ITGA11', 'CSH1', 'CHAD', 'CAB39', 'EIF4E2', 'ITGA7', 'COL4A2', 'COL2A1', 'EGF', 'FGF2', 'ITGAV', 'KDR', 'HIF3A', 'PFKFB2', 'TNN', 'TEK', 'PGF', 'CSF3R', 'RAB14', 'ATF4', 'KRAS', 'PIK3C2B', 'COL5A1', 'EPO', 'FGF13', 'PDGFRA', 'PRLR', 'THBS4', 'GHR', 'LAMA4', 'PPP2R5D', 'PDGFRB', 'FGF1', 'TNR', 'ITGA4', 'FGF12', 'PFKFB4', 'SPP1', 'STK11', 'PDGFB', 'PIK3IP1', 'OSM', 'EFNA2', 'PPP2R3C', 'ANGPT2', 'NOS1', 'RAB10', 'FLT1', 'FGF9', 'CAB39L', 'FGF14', 'LAMA1', 'ANGPT4', 'TCL1A', 'FGF11', 'ITGA5', 'FGFR4', 'SLC2A2', 'FGF19', 'DDIT4', 'RAB8A', 'HSP90B1', 'NOS3', 'ITGA2', 'EFNA1', 'IL7R', 'CHRM1', 'TNXB', 'CREB3L1', 'KIT', 'ITGAD', 'PPP2R2B', 'FGF18', 'PFKFB1', 'CRTC2', 'IL6R', 'IFNAR2', 'FGF17', 'PTEN', 'IFNB1', 'LPAR3', 'PDGFD', 'PFKFB3', 'PTK2', 'EIF4E1B', 'PPP2R2D', 'CSF1R', 'CREB3L2', 'CHRM2', 'GRB2', 'EFNA5', 'COL4A1', 'EPOR', 'FGF3', 'THBS2', 'IL3RA', 'RAB11B', 'LPAR5', 'RELN', 'STRADA', 'ACACA', 'EFNA4', 'IFNA7', 'LAMB3', 'LAMA2', 'FGF16', 'ATF6B', 'TCL1B', 'AKT1S1', 'COL5A2', 'COL11A2', 'LPAR1', 'COL4A6', 'PDGFA']}, {'KEID': 'https://identifiers.org/aop.events/388', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/1262', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/1262', 'WPtitle': 'Apoptosis modulation and signaling', 'gene': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53']}, {'KEID': 'https://identifiers.org/aop.events/1945', 'WPtitle': 'PI3K-Akt signaling', 'gene': ['NFKB1', 'COL1A1', 'VTN', 'COMP', 'PIK3CG', 'FGF8', 'RPS6KB1', 'ITGB8', 'RHEB', 'PPP2CA', 'VEGFA', 'IL4', 'CCND1', 'CDKN1B', 'IL2', 'COL9A1', 'GNB3', 'PKN1', 'CD19', 'BAD', 'CDKN1A', 'BRCA1', 'IGF1', 'COL9A2', 'GNB5', 'IL4R', 'PIK3CB', 'LAMC2', 'HSP90AA1', 'GSK3B', 'PPP2R5C', 'GNB1', 'EIF4EBP1', 'MTOR', 'SGK3', 'SGK2', 'NTF3', 'NTF4', 'LAMB1', 'ITGA6', 'ITGB5', 'JAK2', 'MAPK1', 'COL9A3', 'HSP90AB1', 'IL2RB', 'SOS2', 'TSC2', 'IKBKB', 'MAPK3', 'CCNE1', 'AKT2', 'PPP2CB', 'GYS1', 'PPP2R1A', 'PIK3R2', 'BDNF', 'F2R', 'RPS6KB2', 'GNG7', 'CSF1', 'GNG12', 'GNG5', 'HRAS', 'VEGFB', 'IKBKG', 'PIK3R6', 'GNG2', 'NRAS', 'INS', 'ITGB3', 'CHUK', 'GNG10', 'TGFA', 'IL3', 'VEGFD', 'TSC1', 'COL1A2', 'SYK', 'MLST8', 'GNG4', 'GNGT2', 'GNG8', 'IRS1', 'THBS3', 'MAP2K1', 'PIK3CD', 'BCL2', 'INSR', 'BCL2L1', 'GNB2', 'LAMB2', 'PRL', 'TP53', 'RPTOR', 'ITGB7', 'PDPK1', 'MCL1', 'PIK3R1', 'AKT1', 'EGFR', 'IL2RG', 'ITGB1', 'EIF4E', 'VEGFC', 'GNG3', 'PRKAA2', 'BCL2L11', 'PRKCA', 'JAK1', 'GNGT1', 'LAMA5', 'PRKAA1', 'ITGB4', 'G6PC1', 'RAF1', 'IL2RA', 'CDK4', 'CASP9', 'NGF', 'LAMC1', 'RAC1', 'MDM2', 'MYC', 'RPS6', 'IL6', 'TLR4', 'THBS1', 'TLR2', 'PPP2R1B', 'CREB1', 'MYB', 'FN1', 'SOS1', 'GNB4', 'ITGB6', 'PIK3R3', 'FASLG', 'ATF2', 'AKT3', 'SGK1', 'GNG11', 'CCND2', 'PIK3CA', 'FOXO3', 'MAP2K2', 'GNG13', 'CDK2', 'PCK1', 'THBS4', 'PRLR', 'VWF', 'FGF6', 'CREB3', 'CSF3', 'LAMA4', 'GHR', 'GYS2', 'PPP2R5D', 'FGF1', 'CSF3R', 'ITGA4', 'PDGFRB', 'FGF12', 'SPP1', 'FGF23', 'TNR', 'STK11', 'PDGFB', 'TCL1A', 'EFNA2', 'OSM', 'COL4A4', 'PHLPP1', 'PPP2R3C', 'FLT3LG', 'ANGPT2', 'MET', 'FGF21', 'JAK3', 'LAMA1', 'FGF14', 'ANGPT4', 'IL7', 'CDC37', 'FGF9', 'FLT1', 'NGFR', 'LPAR2', 'CREB3L3', 'EIF4B', 'PPP2R5A', 'FGFR2', 'LAMC3', 'LAMA3', 'TNC', 'KITLG', 'FGFR1', 'ITGA8', 'PPP2R2C', 'FGF4', 'FGF20', 'FGFR3', 'FGF22', 'PPP2R3A', 'PPP2R5B', 'FGF10', 'ITGA3', 'ITGA2B', 'FLT4', 'PHLPP2', 'HGF', 'IBSP', 'PCK2', 'CCND3', 'CCNE2', 'CDK6', 'PPP2R2A', 'RELA', 'ATF6B', 'NTRK1', 'TCL1B', 'RELN', 'LAMA2', 'COL4A1', 'COL4A6', 'LPAR1', 'LAMB3', 'PDGFA', 'EFNA4', 'GH1', 'ITGA1', 'IFNA7', 'PTEN', 'PPP2R2D', 'LPAR3', 'IFNB1', 'EIF4E1B', 'CHRM1', 'PTK2', 'PDGFD', 'IL7R', 'EFNA1', 'FGF3', 'EPOR', 'IL3RA', 'THBS2', 'GRB2', 'CHRM2', 'EFNA5', 'LPAR5', 'CREB3L2', 'CSF1R', 'KIT', 'CREB3L1', 'FGF18', 'PPP2R2B', 'THEM4', 'FGF17', 'IFNAR2', 'PPP2R5E', 'ANGPT1', 'NTRK2', 'NOS3', 'HSP90B1', 'FGF19', 'ITGA2', 'DDIT4', 'TNXB', 'ITGA5', 'FGF11', 'IL6R', 'FGFR4', 'COL2A1', 'LPAR6', 'FGF2', 'EGF', 'PIK3R5', 'COL6A1', 'FGF7', 'IGF1R', 'IFNAR1', 'COL6A2', 'EPHA2', 'EFNA3', 'ITGA10', 'CREB3L4', 'OSMR', 'CREB5', 'ITGA9', 'PDGFC', 'LPAR4', 'PGF', 'TEK', 'FLT3', 'KDR', 'TNN', 'EPO', 'ATF4', 'FGF13', 'PDGFRA', 'COL4A2', 'KRAS', 'CHAD', 'CSH1', 'ITGA7', 'EIF4E2', 'FGF5', 'ITGA11', 'ITGAV', 'COL4A3', 'COL4A5', 'CSH2', 'PIK3AP1', 'PKN3', 'G6PC3', 'G6PC2', 'PKN2', 'LAMB4', 'IFNA21', 'IFNA5', 'IFNA6', 'IFNA8', 'IFNA16', 'PPP2R3B', 'IFNA17', 'IFNA4', 'IFNA14', 'IFNA13', 'IFNA2', 'IFNA1', 'IFNA10', 'RBL2', 'GH2', 'IGF2', 'COL6A6', 'COL6A3', 'COL6A5']}, {'KEID': 'https://identifiers.org/aop.events/1945', 'WPtitle': 'Ras signaling', 'gene': ['BAD', 'MAPK9', 'PIK3CB', 'GNGT1', 'RAC2', 'SHC2', 'PAK4', 'ELK1', 'MAP2K2', 'GNG13', 'GNG11', 'PAK6', 'RAF1', 'RAC1', 'GNB4', 'ZAP70', 'GNB3', 'FASLG', 'PIK3CA', 'SOS1', 'AKT3', 'PIK3R3', 'PAK5', 'MAPK3', 'IKBKB', 'AKT2', 'MAPK1', 'SOS2', 'MAPK8', 'NFKB1', 'MAPK10', 'PIK3R2', 'GNB5', 'PAK3', 'GNB1', 'ABL1', 'RHOA', 'GNGT2', 'GNG8', 'GNG4', 'MAP2K1', 'PRKCB', 'SHC3', 'HTR7', 'AKT1', 'PIK3R1', 'RASA1', 'EGFR', 'PAK1', 'PRKCA', 'SHC1', 'GNG3', 'GNG10', 'CHUK', 'IKBKG', 'HRAS', 'GNG7', 'PTPN11', 'PAK2', 'GNG5', 'GNG2', 'PLCG2', 'CALM1', 'NRAS', 'LAT', 'RAC3', 'INSR', 'BCL2L1', 'PIK3CD', 'GNB2', 'GNG12', 'PLA2G4A', 'PLA2G2D', 'EXOC2', 'RASGRF2', 'PDGFRB', 'RAP1A', 'RASAL3', 'PLA2G4C', 'RASA4', 'FLT1', 'RASAL1', 'RAB5B', 'SHOC2', 'RAB5C', 'GAB1', 'PLD1', 'FGFR1', 'CDC42', 'PRKACA', 'RASAL2', 'PLA2G3', 'STK4', 'BRAP', 'RALA', 'RALBP1', 'GAB2', 'FLT4', 'FGFR2', 'RASSF1', 'FGFR3', 'RASGRP2', 'PLA2G10', 'RASGRF1', 'NGFR', 'AFDN', 'ABL2', 'RGL1', 'CALM2', 'RALB', 'RAB5A', 'EPHA2', 'PRKACB', 'RASA2', 'TIAM1', 'KIT', 'PLA1A', 'TTBK1', 'NTRK2', 'RASGRP3', 'RRAS2', 'PDGFRA', 'ETS1', 'RAPGEF5', 'PLD2', 'KRAS', 'IGF1R', 'KSR1', 'PLCE1', 'PLA2G12B', 'PLCG1', 'TEK', 'FLT3', 'PLA2G12A', 'RRAS', 'PRKCG', 'RAP1B', 'PLA2G5', 'KDR', 'CALML4', 'RASGRP1', 'CALML6', 'PLA2G1B', 'KSR2', 'RASGRP4', 'PLAAT3', 'GRIN1', 'GRB2', 'CALML3', 'CALML5', 'RIN1', 'FGFR4', 'ETS2', 'MRAS', 'PLA2G2F', 'PLA2G4D', 'CALM3', 'RALGDS', 'JMJD7-PLA2G4B', 'PRKACG', 'ARF6', 'PLA2G4F', 'MET', 'RGL2', 'PLA2G4B', 'RASSF5', 'GRIN2B', 'NTRK1', 'SHC4', 'RASA3', 'CSF1R', 'GRIN2A', 'PLA2G6', 'FOXO4', 'PLA2G2C', 'PLA2G4E', 'PLA2G2A', 'PLA2G2E', 'SYNGAP1', 'NF1', 'RELA', 'REL']}, {'KEID': 'https://identifiers.org/aop.events/1945', 'WPtitle': 'Autophagy', 'gene': ['MTOR', 'RPTOR', 'PRKAA1', 'PRKAB2', 'MAP1LC3B', 'PRKAA2', 'MLST8', 'ATG3', 'ATG12', 'AMBRA1', 'PRKAB1', 'PRKAG3', 'ATG101', 'BECN1', 'PIK3C3', 'RB1CC1', 'ATG5', 'PRKAG2', 'ATG16L1', 'PRKAG1', 'ATG13', 'ULK1', 'PIK3R4', 'ATG7', 'ATG14', 'WIPI2', 'AKT1S1', 'DEPTOR', 'ATG9A', 'UVRAG']}, {'KEID': 'https://identifiers.org/aop.events/1945', 'WPtitle': 'PI3K-Akt signaling', 'gene': ['NFKB1', 'COL1A1', 'VTN', 'COMP', 'PIK3CG', 'FGF8', 'RPS6KB1', 'ITGB8', 'RHEB', 'PPP2CA', 'VEGFA', 'IL4', 'CCND1', 'CDKN1B', 'IL2', 'COL9A1', 'GNB3', 'PKN1', 'CD19', 'BAD', 'CDKN1A', 'BRCA1', 'IGF1', 'COL9A2', 'GNB5', 'IL4R', 'PIK3CB', 'LAMC2', 'HSP90AA1', 'GSK3B', 'PPP2R5C', 'GNB1', 'EIF4EBP1', 'MTOR', 'SGK3', 'SGK2', 'NTF3', 'NTF4', 'LAMB1', 'ITGA6', 'ITGB5', 'JAK2', 'MAPK1', 'COL9A3', 'HSP90AB1', 'IL2RB', 'SOS2', 'TSC2', 'IKBKB', 'MAPK3', 'CCNE1', 'AKT2', 'PPP2CB', 'GYS1', 'PPP2R1A', 'PIK3R2', 'BDNF', 'F2R', 'RPS6KB2', 'GNG7', 'CSF1', 'GNG12', 'GNG5', 'HRAS', 'VEGFB', 'IKBKG', 'PIK3R6', 'GNG2', 'NRAS', 'INS', 'ITGB3', 'CHUK', 'GNG10', 'TGFA', 'IL3', 'VEGFD', 'TSC1', 'COL1A2', 'SYK', 'MLST8', 'GNG4', 'GNGT2', 'GNG8', 'IRS1', 'THBS3', 'MAP2K1', 'PIK3CD', 'BCL2', 'INSR', 'BCL2L1', 'GNB2', 'LAMB2', 'PRL', 'TP53', 'RPTOR', 'ITGB7', 'PDPK1', 'MCL1', 'PIK3R1', 'AKT1', 'EGFR', 'IL2RG', 'ITGB1', 'EIF4E', 'VEGFC', 'GNG3', 'PRKAA2', 'BCL2L11', 'PRKCA', 'JAK1', 'GNGT1', 'LAMA5', 'PRKAA1', 'ITGB4', 'G6PC1', 'RAF1', 'IL2RA', 'CDK4', 'CASP9', 'NGF', 'LAMC1', 'RAC1', 'MDM2', 'MYC', 'RPS6', 'IL6', 'TLR4', 'THBS1', 'TLR2', 'PPP2R1B', 'CREB1', 'MYB', 'FN1', 'SOS1', 'GNB4', 'ITGB6', 'PIK3R3', 'FASLG', 'ATF2', 'AKT3', 'SGK1', 'GNG11', 'CCND2', 'PIK3CA', 'FOXO3', 'MAP2K2', 'GNG13', 'CDK2', 'PCK1', 'THBS4', 'PRLR', 'VWF', 'FGF6', 'CREB3', 'CSF3', 'LAMA4', 'GHR', 'GYS2', 'PPP2R5D', 'FGF1', 'CSF3R', 'ITGA4', 'PDGFRB', 'FGF12', 'SPP1', 'FGF23', 'TNR', 'STK11', 'PDGFB', 'TCL1A', 'EFNA2', 'OSM', 'COL4A4', 'PHLPP1', 'PPP2R3C', 'FLT3LG', 'ANGPT2', 'MET', 'FGF21', 'JAK3', 'LAMA1', 'FGF14', 'ANGPT4', 'IL7', 'CDC37', 'FGF9', 'FLT1', 'NGFR', 'LPAR2', 'CREB3L3', 'EIF4B', 'PPP2R5A', 'FGFR2', 'LAMC3', 'LAMA3', 'TNC', 'KITLG', 'FGFR1', 'ITGA8', 'PPP2R2C', 'FGF4', 'FGF20', 'FGFR3', 'FGF22', 'PPP2R3A', 'PPP2R5B', 'FGF10', 'ITGA3', 'ITGA2B', 'FLT4', 'PHLPP2', 'HGF', 'IBSP', 'PCK2', 'CCND3', 'CCNE2', 'CDK6', 'PPP2R2A', 'RELA', 'ATF6B', 'NTRK1', 'TCL1B', 'RELN', 'LAMA2', 'COL4A1', 'COL4A6', 'LPAR1', 'LAMB3', 'PDGFA', 'EFNA4', 'GH1', 'ITGA1', 'IFNA7', 'PTEN', 'PPP2R2D', 'LPAR3', 'IFNB1', 'EIF4E1B', 'CHRM1', 'PTK2', 'PDGFD', 'IL7R', 'EFNA1', 'FGF3', 'EPOR', 'IL3RA', 'THBS2', 'GRB2', 'CHRM2', 'EFNA5', 'LPAR5', 'CREB3L2', 'CSF1R', 'KIT', 'CREB3L1', 'FGF18', 'PPP2R2B', 'THEM4', 'FGF17', 'IFNAR2', 'PPP2R5E', 'ANGPT1', 'NTRK2', 'NOS3', 'HSP90B1', 'FGF19', 'ITGA2', 'DDIT4', 'TNXB', 'ITGA5', 'FGF11', 'IL6R', 'FGFR4', 'COL2A1', 'LPAR6', 'FGF2', 'EGF', 'PIK3R5', 'COL6A1', 'FGF7', 'IGF1R', 'IFNAR1', 'COL6A2', 'EPHA2', 'EFNA3', 'ITGA10', 'CREB3L4', 'OSMR', 'CREB5', 'ITGA9', 'PDGFC', 'LPAR4', 'PGF', 'TEK', 'FLT3', 'KDR', 'TNN', 'EPO', 'ATF4', 'FGF13', 'PDGFRA', 'COL4A2', 'KRAS', 'CHAD', 'CSH1', 'ITGA7', 'EIF4E2', 'FGF5', 'ITGA11', 'ITGAV', 'COL4A3', 'COL4A5', 'CSH2', 'PIK3AP1', 'PKN3', 'G6PC3', 'G6PC2', 'PKN2', 'LAMB4', 'IFNA21', 'IFNA5', 'IFNA6', 'IFNA8', 'IFNA16', 'PPP2R3B', 'IFNA17', 'IFNA4', 'IFNA14', 'IFNA13', 'IFNA2', 'IFNA1', 'IFNA10', 'RBL2', 'GH2', 'IGF2', 'COL6A6', 'COL6A3', 'COL6A5']}, {'KEID': 'https://identifiers.org/aop.events/1945', 'WPtitle': 'Ras signaling', 'gene': ['BAD', 'MAPK9', 'PIK3CB', 'GNGT1', 'RAC2', 'SHC2', 'PAK4', 'ELK1', 'MAP2K2', 'GNG13', 'GNG11', 'PAK6', 'RAF1', 'RAC1', 'GNB4', 'ZAP70', 'GNB3', 'FASLG', 'PIK3CA', 'SOS1', 'AKT3', 'PIK3R3', 'PAK5', 'MAPK3', 'IKBKB', 'AKT2', 'MAPK1', 'SOS2', 'MAPK8', 'NFKB1', 'MAPK10', 'PIK3R2', 'GNB5', 'PAK3', 'GNB1', 'ABL1', 'RHOA', 'GNGT2', 'GNG8', 'GNG4', 'MAP2K1', 'PRKCB', 'SHC3', 'HTR7', 'AKT1', 'PIK3R1', 'RASA1', 'EGFR', 'PAK1', 'PRKCA', 'SHC1', 'GNG3', 'GNG10', 'CHUK', 'IKBKG', 'HRAS', 'GNG7', 'PTPN11', 'PAK2', 'GNG5', 'GNG2', 'PLCG2', 'CALM1', 'NRAS', 'LAT', 'RAC3', 'INSR', 'BCL2L1', 'PIK3CD', 'GNB2', 'GNG12', 'PLA2G4A', 'PLA2G2D', 'EXOC2', 'RASGRF2', 'PDGFRB', 'RAP1A', 'RASAL3', 'PLA2G4C', 'RASA4', 'FLT1', 'RASAL1', 'RAB5B', 'SHOC2', 'RAB5C', 'GAB1', 'PLD1', 'FGFR1', 'CDC42', 'PRKACA', 'RASAL2', 'PLA2G3', 'STK4', 'BRAP', 'RALA', 'RALBP1', 'GAB2', 'FLT4', 'FGFR2', 'RASSF1', 'FGFR3', 'RASGRP2', 'PLA2G10', 'RASGRF1', 'NGFR', 'AFDN', 'ABL2', 'RGL1', 'CALM2', 'RALB', 'RAB5A', 'EPHA2', 'PRKACB', 'RASA2', 'TIAM1', 'KIT', 'PLA1A', 'TTBK1', 'NTRK2', 'RASGRP3', 'RRAS2', 'PDGFRA', 'ETS1', 'RAPGEF5', 'PLD2', 'KRAS', 'IGF1R', 'KSR1', 'PLCE1', 'PLA2G12B', 'PLCG1', 'TEK', 'FLT3', 'PLA2G12A', 'RRAS', 'PRKCG', 'RAP1B', 'PLA2G5', 'KDR', 'CALML4', 'RASGRP1', 'CALML6', 'PLA2G1B', 'KSR2', 'RASGRP4', 'PLAAT3', 'GRIN1', 'GRB2', 'CALML3', 'CALML5', 'RIN1', 'FGFR4', 'ETS2', 'MRAS', 'PLA2G2F', 'PLA2G4D', 'CALM3', 'RALGDS', 'JMJD7-PLA2G4B', 'PRKACG', 'ARF6', 'PLA2G4F', 'MET', 'RGL2', 'PLA2G4B', 'RASSF5', 'GRIN2B', 'NTRK1', 'SHC4', 'RASA3', 'CSF1R', 'GRIN2A', 'PLA2G6', 'FOXO4', 'PLA2G2C', 'PLA2G4E', 'PLA2G2A', 'PLA2G2E', 'SYNGAP1', 'NF1', 'RELA', 'REL']}, {'KEID': 'https://identifiers.org/aop.events/1945', 'WPtitle': 'Autophagy', 'gene': ['MTOR', 'RPTOR', 'PRKAA1', 'PRKAB2', 'MAP1LC3B', 'PRKAA2', 'MLST8', 'ATG3', 'ATG12', 'AMBRA1', 'PRKAB1', 'PRKAG3', 'ATG101', 'BECN1', 'PIK3C3', 'RB1CC1', 'ATG5', 'PRKAG2', 'ATG16L1', 'PRKAG1', 'ATG13', 'ULK1', 'PIK3R4', 'ATG7', 'ATG14', 'WIPI2', 'AKT1S1', 'DEPTOR', 'ATG9A', 'UVRAG']}, {'KEID': 'https://identifiers.org/aop.events/2009', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/2009', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/2009', 'WPtitle': 'Cells and molecules involved in local acute inflammatory response', 'gene': ['SELPLG', 'TNF', 'IL6', 'ITGB1', 'CXCL8', 'ITGB2', 'IL1A', 'VCAM1', 'ICAM1', 'C3', 'SELP', 'C5', 'C7', 'C6', 'ITGA4', 'ITGAL', 'KNG1']}, {'KEID': 'https://identifiers.org/aop.events/2012', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/2012', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/2012', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1770', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/1818', 'WPtitle': 'Type II interferon signaling', 'gene': ['PSMB9', 'ISG15', 'CXCL10', 'NOS2', 'IFNGR1', 'IFNGR2', 'IFI6', 'ICAM1', 'CXCL9', 'PRKCD', 'IFNB1', 'HLA-B', 'CIITA', 'OAS1', 'IFNA2', 'IRF1', 'TAP1', 'REG1A', 'IRF4', 'IRF8', 'IRF2', 'SOCS3', 'STAT1', 'STAT2', 'H4C1', 'SOCS1', 'IFIT2', 'IRF9', 'PTPN11', 'CYBB', 'IL1B', 'IFNG', 'JAK2', 'JAK1', 'SPI1', 'GBP1', 'EIF2AK2']}, {'KEID': 'https://identifiers.org/aop.events/1818', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1818', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1818', 'WPtitle': 'Chemokine signaling', 'gene': ['RAC1', 'VAV3', 'RAF1', 'AKT1', 'VAV1', 'ARRB2', 'ADCY3', 'ARRB1', 'ELMO1', 'CCL28', 'PAK1', 'SHC3', 'PIK3R1', 'CXCL5', 'GNG3', 'SHC1', 'VAV2', 'NCF1', 'MAP2K1', 'STAT3', 'GNG4', 'GNG8', 'CRK', 'GNGT2', 'PRKCB', 'HRAS', 'GNG5', 'GNG12', 'GNB2', 'PIK3CD', 'STAT2', 'GNG2', 'GNG7', 'GRK6', 'LYN', 'GNG10', 'CHUK', 'NRAS', 'CCL5', 'IKBKG', 'ROCK1', 'CCL26', 'FGR', 'CCL22', 'PLCB4', 'CRKL', 'CCR6', 'CXCL9', 'PLCB2', 'CCL21', 'ROCK2', 'CXCL13', 'PLCB3', 'CXCL11', 'PRKCD', 'CXCL3', 'CXCL16', 'CCL15', 'CCL27', 'CXCR2', 'ADCY2', 'CDC42', 'RASGRP2', 'PRKCZ', 'GNAI3', 'GNAI2', 'CCL1', 'JAK3', 'RAP1A', 'KRAS', 'ADCY4', 'GNAI1', 'RAP1B', 'CXCR4', 'CCR2', 'ADCY7', 'ADCY8', 'PRKACB', 'PIK3R5', 'PARD3', 'PRKACG', 'ADCY1', 'PF4', 'PPBP', 'ADCY9', 'BRAF', 'TIAM1', 'GRB2', 'ADCY6', 'STAT5B', 'ADCY5', 'RELA', 'GRK2', 'CCL11', 'PTK2', 'CXCL10', 'CCL3', 'CCL4', 'GRK5', 'SHC4', 'CCR3', 'PLCB1', 'CX3CL1', 'WAS', 'CCL17', 'CSK', 'NFKBIB', 'CCL24', 'WASL', 'CCL7', 'ITK', 'PTK2B', 'PREX1', 'GRK4', 'CCR7', 'CCL25', 'DOCK2', 'XCL1', 'CXCL14', 'TIAM2', 'CXCR5', 'CCR1', 'CX3CR1', 'CXCR6', 'CCL19', 'XCR1', 'CCR9', 'CCR8', 'CCR4', 'PRKX', 'CCR10', 'GRK1', 'CXCR3', 'BCAR1', 'PIK3CB', 'GNB5', 'GNB1', 'GSK3B', 'PXN', 'JAK2', 'MAPK1', 'SOS2', 'NFKBIA', 'HCK', 'MAPK3', 'IKBKB', 'AKT2', 'PIK3R2', 'PIK3CG', 'CXCL12', 'NFKB1', 'GNB3', 'GNB4', 'CCL20', 'STAT1', 'SOS1', 'AKT3', 'PIK3R3', 'FOXO3', 'PIK3CA', 'GNG13', 'GNG11', 'GNGT1', 'RAC2', 'SHC2']}, {'KEID': 'https://identifiers.org/aop.events/1738', 'WPtitle': 'Soluble ACE2-mediated cell entry of SARS-CoV-2', 'gene': ['AVPR1B', 'ACE2', 'AGTR1', 'ADAM17']}, {'KEID': 'https://identifiers.org/aop.events/1752', 'WPtitle': 'Angiotensin II receptor type 1 pathway', 'gene': ['ACTA2', 'COL1A1', 'MAP2K6', 'MAPK1', 'HIF1A', 'TGFB1', 'PTPN11', 'SP1', 'COL1A2', 'JUND', 'RAF1', 'SMAD4', 'IL11', 'TGFBR2', 'CCN2', 'TGFBR1', 'RRAS', 'F12', 'IL11RA', 'IL6ST', 'AGTR1', 'NOX4', 'RACK1', 'AGT', 'MAS1', 'ACE2', 'PDGFD', 'SMAD3']}, {'KEID': 'https://identifiers.org/aop.events/1752', 'WPtitle': 'Renin-angiotensin-aldosterone system (RAAS', 'gene': ['CAMK1G', 'CAMK1D', 'CREB3', 'CAMK1', 'CREB3L1', 'AGTR2', 'AGTR1', 'AGT', 'CMA1', 'CREB3L3', 'CREB3L2', 'CREB5', 'CREB3L4', 'ITPR2', 'ITPR1', 'CALML6', 'CALML5', 'CALML4', 'CALML3', 'CALM2', 'ATF6B', 'ATF4', 'STAR', 'ITPR3', 'CYP21A2', 'CYP11A1', 'ACE', 'HSD3B1', 'HSD3B2', 'CYP11B2', 'CAMK2A', 'CALM1', 'CAMK2B', 'CAMK4', 'CAMK2D', 'CREB1', 'GNAQ', 'CALM3', 'ATF2', 'REN', 'CAMK2G', 'ATF1', 'PLCB2', 'CTSG']}, {'KEID': 'https://identifiers.org/aop.events/887', 'WPtitle': 'Mitochondrial complex I assembly model OXPHOS system', 'gene': ['NDUFAF1', 'NDUFB9', 'ACAD9', 'NDUFAB1', 'ECSIT', 'COA1', 'TIMMDC1', 'FOXRED1', 'DMAC1', 'NDUFAF3', 'TMEM70', 'NUBPL', 'TMEM186', 'MT-ND6', 'NDUFAF6', 'NDUFAF7', 'TMEM126B', 'MT-ND2', 'MT-ND4L', 'MT-ND4', 'MT-ND5', 'DMAC2', 'NDUFAF4', 'NDUFA2', 'NDUFS5', 'NDUFS2', 'NDUFS6', 'NDUFS4', 'NDUFB5', 'NDUFB3', 'NDUFC1', 'NDUFA1', 'NDUFB1', 'MT-ND1', 'NDUFAF2', 'NDUFA13', 'NDUFB11', 'NDUFA12', 'NDUFA8', 'NDUFV3', 'NDUFA6', 'NDUFA5', 'NDUFB7', 'NDUFV2', 'NDUFS1', 'NDUFV1', 'NDUFC2', 'NDUFA10', 'NDUFB10', 'NDUFB4', 'NDUFB8', 'NDUFB2', 'NDUFA7', 'NDUFS3', 'NDUFB6', 'NDUFA3']}, {'KEID': 'https://identifiers.org/aop.events/887', 'WPtitle': 'Oxidative phosphorylation', 'gene': ['NDUFB9', 'ATP5MF', 'ATP5MC3', 'ATP5ME', 'ATP5PF', 'ATP6AP1', 'ATP5PO', 'ATP5MC1', 'ATP5MC2', 'NDUFAB1', 'ATP5F1A', 'ATP5F1B', 'ATP5F1D', 'ATP5F1E', 'DMAC2L', 'ATP5PB', 'ATP5PD', 'ATP5MG', 'MT-ATP6', 'MT-ND2', 'MT-ND3', 'MT-ND4', 'MT-ND4L', 'MT-ND5', 'MT-ND6', 'GZMB', 'MT-ND1', 'ATP6AP2', 'NDUFA4', 'NDUFA4L2', 'NDUFS1', 'NDUFS2', 'NDUFS3', 'NDUFV1', 'NDUFS4', 'NDUFS5', 'NDUFS6', 'NDUFS8', 'NDUFV2', 'NDUFV3', 'NDUFB1', 'NDUFB2', 'NDUFB4', 'NDUFB5', 'NDUFB6', 'NDUFB7', 'NDUFB8', 'NDUFB10', 'NDUFC1', 'NDUFC2', 'NDUFA11', 'NDUFS7', 'NDUFA2', 'NDUFA3', 'NDUFA5', 'NDUFA6', 'NDUFA7', 'NDUFA8', 'NDUFA9', 'NDUFA10']}, {'KEID': 'https://identifiers.org/aop.events/1585', 'WPtitle': 'Unfolded protein response', 'gene': ['MBTPS1', 'ATF4', 'MBTPS2', 'NFE2L2', 'HSPA5', 'PPP1R15A', 'XBP1', 'ATF6', 'EIF2S1', 'ERN1', 'DDIT3', 'EIF2AK3', 'BBC3', 'TNFRSF10B', 'IL1B', 'TP53', 'PMAIP1', 'BID', 'TXNIP', 'BCL2L11', 'BCL2', 'RTCB', 'CASP2']}, {'KEID': 'https://identifiers.org/aop.events/1585', 'WPtitle': 'Cellular proteostasis', 'gene': ['PFDN6', 'VBP1', 'PFDN2', 'PFDN1', 'PFDN5', 'PFDN4']}, {'KEID': 'https://identifiers.org/aop.events/214', 'WPtitle': 'Bile acid synthesis and enterohepatic circulation', 'gene': ['LDLR', 'CYP7A1', 'ABCG8', 'ABCG5', 'MAPK3', 'MAPK1', 'FXR1', 'SLC10A2', 'FGFR4', 'SLC10A1', 'FGF19', 'ABCB11']}, {'KEID': 'https://identifiers.org/aop.events/214', 'WPtitle': 'Cholestasis', 'gene': ['ATP8B1', 'HMGCR', 'LDLR', 'ABCC2', 'SCARB1', 'ABCG8', 'RXRA', 'TJP2', 'ABCG5', 'SLC22A1', 'ABCB4', 'NR1I3', 'SLC10A1', 'NR1H4', 'SLCO1A2', 'EPHX1', 'ABCC3', 'ABCB11', 'ABCC4']}, {'KEID': 'https://identifiers.org/aop.events/214', 'WPtitle': 'Farnesoid X receptor pathway', 'gene': ['UGT2B4', 'IRS2', 'SLC27A5', 'CYP8B1', 'IP6K3', 'ABCB4', 'NR0B2', 'SULT2A1', 'NR1H4', 'FGF19', 'BAAT', 'SLC10A1', 'ABCB11', 'SLCO2B1', 'RXRA', 'CYP7A1', 'CYP3A4', 'PPARGC1A', 'FKBP5']}, {'KEID': 'https://identifiers.org/aop.events/1271', 'WPtitle': 'TGF-beta receptor signaling', 'gene': ['ZFYVE9', 'ENG', 'RUNX3', 'TGFBR3', 'LEF1', 'FKBP1A', 'BAMBI', 'FST', 'EGF', 'FOXH1', 'NOG', 'SERPINE1', 'TGFBR2', 'TGFBR1', 'LEFTY2', 'SPP1', 'SKIL', 'SMAD3', 'SMAD2', 'SMAD7', 'SMAD6', 'LIF', 'INHBA', 'SKI', 'TGIF1', 'ZNF423', 'LEFTY1', 'ZEB2', 'LTBP1', 'SMAD1', 'SMAD4', 'SMAD5', 'JAK1', 'JUN', 'SMAD9', 'CTNNB1', 'EP300', 'FOS', 'HRAS', 'CREBBP', 'IFNG', 'ITGB6', 'TFE3', 'RUNX2', 'BMP4', 'MAPK3', 'MAPK9', 'TNF', 'WNT1', 'STAT1', 'STAT3', 'TGFB1', 'THBS1', 'NFKB1', 'MIR302A']}, {'KEID': 'https://identifiers.org/aop.events/1087', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/1087', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1087', 'WPtitle': 'MAPK signaling', 'gene': ['CACNA1G', 'CACNA2D2', 'MAPK8IP2', 'CACNB1', 'CACNG5', 'CACNG4', 'CACNA1S', 'MKNK2', 'CACNA1I', 'CACNA1F', 'CACNG7', 'DUSP3', 'CACNG1', 'RAPGEF2', 'DUSP16', 'MAPK8IP1', 'HSPA2', 'CACNG6', 'DUSP9', 'TAOK3', 'MAPK8IP3', 'CACNA1A', 'CACNG8', 'CACNA2D4', 'CACNA1C', 'CACNA2D1', 'CACNA1D', 'CACNA2D3', 'CACNG2', 'CACNB3', 'HSPA6', 'CACNB4', 'DUSP8', 'NTF3', 'CACNA1H', 'CACNA1E', 'HSPA1B', 'HSPA1L', 'NTF4', 'CACNG3', 'DUSP10', 'DUSP4', 'DUSP6', 'DUSP7', 'HSPB1', 'MAPT', 'MAX', 'NLK', 'MAP3K20', 'PPM1A', 'PPM1B', 'PPP3CB', 'PPP3CC', 'PPP3R1', 'PPP3R2', 'TAOK1', 'PTPN7', 'PTPRR', 'PTPN5', 'MAPKAPK5', 'MKNK1', 'TAOK2', 'MAP3K14', 'TNFRSF1A', 'FGF8', 'SOS1', 'NGF', 'PRKCA', 'RPS6KA4', 'MAP4K2', 'RAC3', 'GNG12', 'HRAS', 'MAPK11', 'LRRK2', 'CHUK', 'AKT3', 'TAB1', 'MAP3K2', 'MAP4K1', 'MAP3K8', 'ATF2', 'CRK', 'MAPK14', 'DAXX', 'EGFR', 'ELK1', 'AKT1', 'AKT2', 'TAB2', 'FOS', 'GNA12', 'HSPA1A', 'FAS', 'IKBKB', 'IL1B', 'IL1R1', 'FASLG', 'JUN', 'JUND', 'ARRB1', 'ARRB2', 'MEF2C', 'MAP3K1', 'MAP3K4', 'MAP3K5', 'MAP3K11', 'MYC', 'NFATC1', 'NFKB1', 'NRAS', 'PAK1', 'PAK2', 'ECSIT', 'PPP3CA', 'PPP5C', 'MAPK1', 'MAPK3', 'MAPK7', 'MAPK8', 'MAPK9', 'MAPK10', 'MAPK13', 'MAP2K1', 'MAP2K2', 'MAP2K3', 'MAP2K5', 'MAP2K6', 'MAP2K7', 'RAC1', 'RAC2', 'RAF1', 'RASA1', 'RPS6KA3', 'BDNF', 'MAPK12', 'MAP2K4', 'SOS2', 'SRF', 'STK3', 'MAP3K7', 'TGFB1', 'TGFB2', 'TGFB3', 'TNF', 'TP53', 'TRAF6', 'MAP3K12', 'IL1R2', 'CASP3', 'MAP4K3', 'IKBKG', 'MAP3K6', 'MAP3K13', 'RPS6KA5', 'CD14', 'MAP4K4', 'NFATC3', 'FLNC', 'FLNB', 'CACNA1B', 'ELK4', 'CACNB2', 'CRKL', 'GADD45A', 'DDIT3', 'DUSP1', 'NR4A1', 'HSPA8', 'IL1A', 'PRKCD', 'LAMTOR3', 'MAPKAPK2', 'CDC25B', 'RASGRF1', 'FGFR2', 'FGFR3', 'RASGRP2', 'FGF10', 'FGF22', 'FGF4', 'NFKB2', 'ARAF', 'FGF20', 'STK4', 'FGF14', 'FGF9', 'RELB', 'PLA2G4C', 'FGF21', 'FGF6', 'FGF1', 'PDGFRB', 'FGF12', 'MAPKAPK3', 'PLA2G4A', 'FGF23', 'RRAS', 'FGF13', 'RRAS2', 'FGF5', 'FGF2', 'FGF7', 'PRKACB', 'NTRK2', 'RASGRP3', 'FGF18', 'DUSP2', 'FGF17', 'PLA2G4D', 'FGFR4', 'FGF11', 'FGF19', 'PRKACG', 'PLA2G4F', 'RASGRP4', 'RELA', 'FGF3', 'PLA2G4E', 'FGF16', 'NF1', 'PDGFA', 'PLA2G4B', 'RASGRP1', 'EGF', 'FGFR1', 'MRAS', 'FLNA', 'GRB2', 'KRAS', 'STMN1', 'ATF4', 'NTRK1', 'PDGFB', 'PRKACA', 'PRKCG', 'RAP1A', 'RAP1B', 'RASA2', 'RASGRF2', 'BRAF', 'TGFBR1', 'TGFBR2', 'TRAF2', 'CDC42']}, {'KEID': 'https://identifiers.org/aop.events/1087', 'WPtitle': 'IL1 signaling', 'gene': ['NFKBIB', 'MAP3K14', 'JUN', 'IRAK1', 'IRAK2', 'IKBKB', 'IL1B', 'IL1R1', 'AKT1', 'MAPK14', 'TAB3', 'TAB2', 'TAB1', 'MAP3K2', 'ATF2', 'IRAK3', 'CHUK', 'IL1A', 'MAP3K7', 'UBE2N', 'UBE2V1', 'TRAF6', 'SQSTM1', 'IKBKG', 'PTPN11', 'MAP2K3', 'MAP2K2', 'PELI2', 'PELI1', 'MAP2K6', 'MAP2K7', 'MAP2K4', 'CCL2', 'MAPK1', 'MAPK3', 'TOLLIP', 'MAP2K1', 'MAPK9', 'MAPK8', 'MAP3K1', 'MAP3K3', 'NFKB1', 'MYD88', 'ECSIT', 'IRAK4', 'PIK3R1', 'PIK3R2', 'NFKBIA', 'REL', 'RELA', 'PLCG1', 'PRKCZ', 'MAPKAPK2', 'IL1RAP', 'HSPB2']}, {'KEID': 'https://identifiers.org/aop.events/1087', 'WPtitle': 'Toll-like receptor signaling', 'gene': ['IFNA2', 'IFNA4', 'IFNA1', 'IRF5', 'IFNA10', 'IFNA13', 'IFNA6', 'IFNA8', 'IFNA17', 'IFNA21', 'IFNA14', 'IFNA16', 'IFNA5', 'NFKBIB', 'NFKBIA', 'IKBKB', 'IKBKG', 'CHUK', 'TLR6', 'AKT3', 'MAPK14', 'TICAM1', 'AKT2', 'AKT1', 'TIRAP', 'TAB1', 'MAP3K8', 'TAB3', 'LY96', 'TICAM2', 'TBK1', 'IL6', 'IL1B', 'IL12A', 'CXCL8', 'FOS', 'TAB2', 'JUN', 'IRF7', 'MYD88', 'NFKB1', 'IRAK4', 'IRF3', 'IRAK1', 'IL12B', 'PIK3CD', 'PIK3CB', 'PIK3R1', 'PIK3CG', 'TLR9', 'PIK3R2', 'TOLLIP', 'TLR7', 'PIK3CA', 'MAPK10', 'MAPK9', 'MAPK13', 'MAP2K2', 'MAP2K1', 'MAPK3', 'MAPK1', 'MAPK11', 'MAPK8', 'CCL5', 'MAPK12', 'MAP2K4', 'MAP2K3', 'MAP2K7', 'MAP2K6', 'RAC1', 'CASP8', 'TRAF6', 'PIK3R3', 'MAP3K7', 'STAT1', 'TLR2', 'TLR1', 'TNF', 'TLR4', 'TRAF3', 'IKBKE', 'FADD', 'RIPK1', 'CD80', 'CD14', 'CD40', 'CD86', 'CXCL11', 'CXCL9', 'RELA', 'IFNA7', 'IFNAR2', 'IFNAR1', 'PIK3R5', 'CCL4', 'TLR3', 'SPP1', 'CXCL10', 'IFNB1', 'TLR8', 'LBP', 'CCL3', 'TLR5']}, {'KEID': 'https://identifiers.org/aop.events/1538', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1538', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/898', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/898', 'WPtitle': 'Apoptosis modulation and signaling', 'gene': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53']}, {'KEID': 'https://identifiers.org/aop.events/195', 'WPtitle': 'GPCRs class C metabotropic glutamate pheromone', 'gene': ['GRM3', 'GPRC5B', 'GPRC5C', 'GPRC5A', 'GRM1', 'GRM2', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GABBR2', 'GRM6', 'CASR', 'GPRC5D', 'GABBR1']}, {'KEID': 'https://identifiers.org/aop.events/195', 'WPtitle': 'Neuroinflammation and glutamatergic signaling', 'gene': ['IL4R', 'IL6', 'IL10', 'IL10RB', 'IGF1', 'IL1B', 'IL1R1', 'IL4', 'IFNG', 'SMAD4', 'INSR', 'IRS1', 'JAK1', 'IL12A', 'IL12B', 'IL13', 'CAMKK2', 'ADCY3', 'CREB1', 'DLD', 'AKT1', 'GRM1', 'PSAT1', 'FOS', 'GLS2', 'GLS', 'ARC', 'CAMK2B', 'CAMK2D', 'CAMK2A', 'CAMKK1', 'SOCS3', 'SLC1A1', 'SLC1A2', 'SLC1A3', 'TGFB1', 'TGFB2', 'TGFB3', 'SLC1A6', 'SLC2A1', 'STAT1', 'STAT3', 'TNF', 'TNFRSF1A', 'CALM1', 'CAMK4', 'TNFRSF1B', 'IL1R2', 'NFKB1', 'SLC17A7', 'PRKCA', 'PRKCB', 'MAPK1', 'MAPK3', 'NGF', 'PDHA1', 'SLC38A2', 'PSPH', 'SHMT2', 'BCL2', 'BDNF', 'GRIK2', 'GRIK3', 'GRIK4', 'GRIK5', 'GRIA2', 'GRIA3', 'GRIA4', 'GRIK1', 'GRIN2C', 'GRIN2D', 'IL1A', 'IL13RA1', 'GRM4', 'GRM5', 'GRM7', 'GRM8', 'GRM2', 'SLC38A3', 'GRIN3A', 'GRIN3B', 'CNTF', 'DAO', 'DLAT', 'LRRC8B', 'NSMF', 'PHGDH', 'GFAP', 'DISC1', 'GOT1', 'SLC6A9', 'CAMK2G', 'LRRC8E', 'SLC38A1', 'STAT6', 'TGFBR3', 'TRAF5', 'LRRC8C', 'SLC38A5', 'GLUL', 'PLCB3', 'PLCB4', 'TRPM4', 'PLCB2', 'LTA', 'SHMT1', 'SLC1A4', 'SLC17A6', 'SRR', 'LRRC8D', 'LRRC8A', 'SLC7A10', 'PPP1CB', 'PPP1CC', 'PRKACA', 'PRKCG', 'NOS1', 'PPP1CA', 'SLC2A3', 'TGFBR1', 'TGFBR2', 'FGF2', 'PLCB1', 'GRIA1', 'GRIN1', 'GRIN2A', 'GRIN2B', 'IL6R', 'IL6ST', 'IL10RA', 'LIF', 'IFNGR1', 'IFNGR2', 'SMAD2', 'SMAD3', 'SMAD7', 'NFKB2', 'CFL1', 'ADCY8', 'ADCY1']}, {'KEID': 'https://identifiers.org/aop.events/459', 'WPtitle': 'Lipid metabolism pathway', 'gene': ['PRKAB1', 'AKT2', 'PRKAG2', 'PRKAR2A', 'PRKAR1A', 'PRKAR2B', 'ACSBG1', 'ABHD5', 'PRKAR1B', 'HILPDA', 'PRKAG3', 'AKT3', 'ACLY', 'PRKAB2', 'PRKAA1', 'PDHA1', 'PRKAA2', 'AKT1', 'FASN', 'PRKAG1', 'ACSS2', 'BCKDHA', 'PRKACA', 'PRKACG', 'PLIN1', 'LIPE', 'PRKACB', 'PNPLA2', 'ACACA']}, {'KEID': 'https://identifiers.org/aop.events/459', 'WPtitle': 'Fatty acid biosynthesis', 'gene': ['ACSL4', 'PECR', 'PC', 'MECR', 'HADH', 'ACSL1', 'FASN', 'ACLY', 'ECHS1', 'ACSS2', 'ACAA2', 'DECR1', 'ACSL3', 'SCD', 'ACACA', 'ECHDC3', 'ECHDC2', 'ACSL5', 'ECHDC1', 'ECH1', 'ACACB', 'ACSL6']}, {'KEID': 'https://identifiers.org/aop.events/459', 'WPtitle': 'Fatty acid beta-oxidation', 'gene': ['CPT1B', 'HADHA', 'ACADS', 'ACADVL', 'ACSL4', 'CRAT', 'LPL', 'ACAT1', 'HADH', 'GCDH', 'ECHS1', 'ACSL1', 'DLD', 'DECR1', 'ECI1', 'ACADL', 'ACSL3', 'CHKB', 'GPD2', 'ACSS2', 'GK2', 'GK', 'SLC25A20', 'TPI1', 'LIPF', 'CPT2', 'ACSL6', 'ACSL5', 'CPT1A', 'PNPLA2', 'LIPE', 'HADHB', 'ACADM', 'LIPC']}, {'KEID': 'https://identifiers.org/aop.events/459', 'WPtitle': 'Fatty acid and lipoprotein transport in hepatocytes', 'gene': ['DBI', 'APOE', 'SOAT1', 'LDLR', 'PCSK9', 'VDAC1', 'ACSL1', 'NPC2', 'SCARB1', 'SLC27A2', 'SORT1', 'APOB', 'ACSL5', 'ACSL6', 'STAR', 'OSBPL5', 'LPA', 'FABP3', 'LDLRAP1', 'SLC27A4', 'LIPA', 'SLC27A1', 'APOA4', 'ACSL3', 'ABCA1', 'MYLIP', 'SLC27A3', 'FABP2', 'APOC1', 'FABP4', 'FABP1', 'LRP1', 'SOAT2', 'STARD3', 'APOC2']}, {'KEID': 'https://identifiers.org/aop.events/341', 'WPtitle': 'Neurotransmitter disorders', 'gene': ['TPH1', 'DDC', 'TH', 'MAOA', 'SLC18A2', 'SLC6A3', 'TPH2', 'COMT', 'PNMT', 'DBH']}, {'KEID': 'https://identifiers.org/aop.events/2008', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1670', 'WPtitle': 'Non-small cell lung cancer', 'gene': ['CASP8', 'BAK1', 'PIK3CB', 'MAPK3', 'MAPK1', 'BAX', 'SOS2', 'RARB', 'CRABP1', 'CDKN1A', 'BID', 'BAD', 'CRABP2', 'PRKCA', 'TGFA', 'CASP3', 'PRKCB', 'STAT3', 'MAP2K1', 'CDK4', 'MAP2K2', 'RAF1', 'CASP9', 'TP53', 'AKT1', 'PIK3R1', 'CDKN2A', 'EGFR', 'CCND1', 'SOS1', 'AKT2', 'PIK3R2', 'POLK', 'PIK3R3', 'AKT3', 'FOXO3', 'PIK3CA', 'HRAS', 'CYCS', 'RXRA', 'PIK3CD', 'PLCG2', 'NRAS', 'GADD45A', 'E2F2', 'CDK6', 'E2F3', 'FHIT', 'EML4', 'RASSF5', 'GRB2', 'PDK1', 'STAT5B', 'BRAF', 'JAK3', 'E2F1', 'PLCG1', 'PRKCG', 'STAT5A', 'DDB2', 'RB1', 'EGF', 'ERBB2', 'KRAS', 'RASSF1', 'ARAF', 'STK4', 'RXRB', 'GADD45B', 'ALK', 'GADD45G', 'RXRG']}, {'KEID': 'https://identifiers.org/aop.events/759', 'WPtitle': 'Wnt signaling in kidney disease', 'gene': ['INVS', 'WNT1', 'WNT5A', 'MAPK10', 'MAPK8', 'WNT16', 'MAPK9', 'RHOA', 'LRP5', 'CTNNB1', 'WNT10B', 'FZD4', 'FZD8', 'FZD5', 'FZD6', 'FZD1', 'FZD7', 'WNT9B', 'WNT4', 'DVL3', 'WNT7A', 'WNT3A', 'WNT10A', 'WNT2B', 'DVL1', 'WNT2', 'WNT3', 'WNT5B', 'WNT6', 'FZD3', 'LRP6', 'WNT11', 'DVL2', 'FZD2', 'FZD9', 'WNT7B']}, {'KEID': 'https://identifiers.org/aop.events/759', 'WPtitle': 'Regucalcin in proximal tubule epithelial kidney cells', 'gene': ['TRPV5', 'MTOR', 'CASP9', 'SMAD4', 'RAF1', 'PTH', 'AKT1', 'ACTA2', 'PIK3CA', 'APAF1', 'TNFSF11', 'CASP8', 'TNFRSF1A', 'BAK1', 'TGFB1', 'BAX', 'MAPK1', 'G3BP1', 'PPP3R1', 'SEC16B', 'MAP3K5', 'CALCA', 'CASP3', 'BRAF', 'TGFBR1', 'FFAR3', 'MCU', 'NOS1', 'SMAD2', 'PDE1B', 'RGN']}, {'KEID': 'https://identifiers.org/aop.events/1941', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1090', 'WPtitle': 'Pleural mesothelioma', 'gene': ['CDH10', 'CD44', 'MAD1L1', 'CTNNA3', 'SETD5', 'FABP4', 'TNIK', 'LATS2', 'CDH12', 'SETDB1', 'CDH24', 'CIT', 'CDH15', 'AMOT', 'TELO2', 'TTI1', 'CDH20', 'CD274', 'HMGN1', 'CDH19', 'CDH7', 'ULK2', 'WNT16', 'CSNK2A3', 'CDKN1A', 'TEAD3', 'MAP3K9', 'NOTUM', 'KREMEN1', 'NTF3', 'ROR1', 'FOSL1', 'FRAT2', 'CSNK1A1L', 'CSNK1E', 'NTF4', 'RYK', 'SOX17', 'SENP2', 'WIF1', 'DKK2', 'FRAT1', 'ROR2', 'CXXC4', 'SFRP5', 'SFRP4', 'MAX', 'NDRG1', 'PRSS23', 'KIF23', 'AJUBA', 'CER1', 'SFRP2', 'MTOR', 'MMP14', 'MKNK1', 'DKK4', 'SFRP1', 'CHD8', 'MKNK2', 'PORCN', 'EIF4EBP1', 'EIF4G1', 'MMP2', 'GSK3B', 'PAK3', 'MAP3K4', 'BAX', 'ITGA6', 'LAMB1', 'MAP2K4', 'MAP2K7', 'MAP4K4', 'CSNK2A2', 'ACTB', 'TEAD2', 'CDH1', 'MAP2K3', 'PIK3CB', 'LAMC2', 'CTNNA1', 'MAPK9', 'MAP4K3', 'RB1CC1', 'WWTR1', 'BAK1', 'BRCA1', 'IGF1', 'SOS1', 'SLC2A1', 'AKT3', 'ATF2', 'MEF2D', 'RPS6KA1', 'FN1', 'STAT1', 'WNT5A', 'PRKAG3', 'CCND1', 'PPARGC1A', 'PRKAB1', 'NFKB1', 'MAPK10', 'VEGFA', 'MAPK14', 'HBEGF', 'RPS6KB1', 'CCL2', 'DKK1', 'FGF8', 'MAP2K6', 'RHEB', 'PIK3CG', 'TGFB1', 'ACTA2', 'CXCL12', 'PRKAG2', 'MAPK8', 'MAP4K1', 'STK3', 'CCNE1', 'BBC3', 'AKT2', 'RPS6KA5', 'YY1', 'AXIN1', 'MAPK3', 'TSC2', 'CSNK2A1', 'MMP9', 'PAK5', 'MAP3K1', 'HIF1A', 'MAPK1', 'WNT1', 'IL1B', 'MAP2K2', 'BECN1', 'ELK1', 'CREB1', 'CDK2', 'PIK3CA', 'CCND2', 'CTNNB1', 'MAP2K1', 'WNT10B', 'MAP4K2', 'LGALS9', 'MAPK7', 'TSC1', 'SOST', 'CTHRC1', 'CSF2', 'VEGFD', 'MLST8', 'JAK1', 'TGFA', 'ACTG2', 'SHC1', 'ITGB2', 'PRKAA2', 'LRP5', 'CXCL1', 'CXCL5', 'SAV1', 'FOXO1', 'VEGFC', 'ACTC1', 'LIMD1', 'EGFR', 'ACTA1', 'MCL1', 'PAK1', 'CDKN2A', 'ITGB1', 'ATM', 'TP53', 'MINK1', 'RPTOR', 'BARD1', 'MAP3K6', 'AKT1', 'RPS6', 'MYC', 'PAK6', 'YAP1', 'MAP2K5', 'CASP1', 'MDM2', 'CDK4', 'IL10', 'LAMC1', 'IL6', 'PRKAA1', 'RAF1', 'NGF', 'ITGB4', 'SERPINF1', 'PAK4', 'IDO1', 'PRKAB2', 'MAP3K10', 'LAMA5', 'LATS1', 'TCF7', 'EED', 'EZH2', 'PLCB4', 'AREG', 'CCL5', 'INS', 'ITGB3', 'MDM4', 'TEAD4', 'CSNK2B', 'MAP3K3', 'NF2', 'SP1', 'TEAD1', 'MAP3K5', 'SRC', 'HMGB1', 'PAK2', 'PRKAG1', 'ACTG1', 'CSF1', 'HRAS', 'RPS6KA3', 'ULK1', 'JUN', 'ATG13', 'BDNF', 'RPS6KB2', 'LAMB2', 'BCL2', 'MST1', 'VEGFB', 'CYCS', 'MAP3K11', 'INSR', 'PIK3CD', 'MAP3K2', 'SPARC', 'LAMA4', 'PDGFRB', 'FGF1', 'FZD10', 'FGF6', 'PHC1', 'ITGA4', 'FGF12', 'DVL1', 'WNT3', 'CSF3', 'WNT2', 'WNT5B', 'FGF9', 'FGF14', 'FZD3', 'FLT1', 'LAMA1', 'FGF21', 'MET', 'FLT3LG', 'EFNA2', 'ANGPT2', 'WNT11', 'E2F1', 'PDGFB', 'ANGPT4', 'FGF22', 'FGF10', 'FGF4', 'COL4A4', 'FGFR1', 'FGF20', 'LAMC3', 'CUL1', 'LAMA3', 'FGFR3', 'RASSF1', 'LRP6', 'EIF4B', 'FGFR2', 'NGFR', 'HGF', 'KITLG', 'FLT4', 'YWHAB', 'ITGA3', 'DVL2', 'CD47', 'AGER', 'MIRLET7B', 'PRB1', 'MAPKAPK2', 'ATF3', 'CDH2', 'DDIT3', 'BTC', 'TCF7L1', 'TCF7L2', 'NLRP3', 'RBBP4', 'CCND3', 'LEF1', 'CSNK1A1', 'HCFC1', 'PTEN', 'CTBP2', 'PTK2', 'CXCL10', 'EFNA1', 'BMI1', 'ASXL1', 'PDGFD', 'MAD2L1', 'BAP1', 'ITGA2', 'TERT', 'BTRC', 'FZD6', 'CTBP1', 'FGF17', 'DVL3', 'FGFR4', 'FZD5', 'FGF19', 'FGF11', 'WNT4', 'WNT7A', 'DEPTOR', 'FZD7', 'FZD1', 'FGF18', 'KIT', 'EFNA3', 'PDK1', 'MMP3', 'WNT3A', 'ANGPT1', 'PDGFC', 'NTRK2', 'OGT', 'WNT10A', 'ITGAV', 'CDH11', 'IGF1R', 'EPHA2', 'FGF2', 'FGF5', 'FGF7', 'EGF', 'PDGFRA', 'APC', 'COL4A2', 'WNT2B', 'CDK7', 'FLT3', 'RNF2', 'PLAU', 'KDR', 'TRAF2', 'FGF13', 'FGF23', 'CCN2', 'TEK', 'PGF', 'WNT6', 'FGF3', 'CSF1R', 'EFNA5', 'LAMA2', 'FZD9', 'PDGFA', 'LAMB3', 'WNT7B', 'COL4A1', 'GRB2', 'FZD2', 'SUZ12', 'FZD8', 'UHRF1', 'GABPA', 'KDM6A', 'IL34', 'ADAMTS1', 'CDH13', 'WDR5', 'COL4A3', 'SLC3A2', 'COL4A5', 'SETD2', 'CDH4', 'MOB1B', 'LIN28B', 'CDH5', 'PODXL', 'FOXM1', 'KMT2C', 'STK38L', 'SLC7A5', 'ITPR3', 'VGLL4', 'CDH22', 'CDH18', 'IGF2', 'CDH16', 'RASSF6', 'PIGF', 'CDH8', 'MCU', 'RASSF3', 'RASSF7', 'TNNT1', 'RASSF2', 'WWC1', 'CDH6', 'DSC3', 'MOB1A', 'MDK', 'RASSF4', 'CDH9', 'BAG2', 'CDH3', 'SELE', 'CDH17', 'CTNNA2', 'NTRK1', 'COL4A6', 'AKT1S1', 'RING1', 'RASSF5', 'CCL4', 'EFNA4', 'ITGA1']}, {'KEID': 'https://identifiers.org/aop.events/1276', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/344', 'WPtitle': 'Matrix metalloproteinases', 'gene': ['MMP2', 'MMP14', 'TIMP2', 'MMP9', 'TNF', 'MMP28', 'MMP7', 'MMP3', 'MMP10', 'MMP8', 'MMP12', 'MMP11', 'MMP13', 'MMP1', 'MMP19', 'MMP15', 'TIMP1', 'TIMP3', 'MMP25', 'MMP20', 'TIMP4', 'TCF20', 'MMP24', 'MMP16', 'MMP21', 'MMP17', 'MMP27', 'MMP26', 'MMP23B', 'BSG']}, {'KEID': 'https://identifiers.org/aop.events/1841', 'WPtitle': 'Post-COVID neuroinflammation', 'gene': []}, {'KEID': 'https://identifiers.org/aop.events/1841', 'WPtitle': 'Neuroinflammation', 'gene': ['MTOR', 'CHUK', 'JUN', 'FOS', 'TLR4', 'NFKBIA', 'MAPK14', 'MAPK8', 'NOS2', 'MT-CO2', 'MT-CO1', 'RELA', 'ASCC1']}, {'KEID': 'https://identifiers.org/aop.events/1820', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1820', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/351', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/896', 'WPtitle': "Parkinson's disease pathway", 'gene': ['PARK7', 'SNCAIP', 'MIR18A', 'EPRS1', 'MIR375', 'GPR37', 'UBE2L6', 'MAPK14', 'DDC', 'HTRA2', 'APAF1', 'LRRK2', 'CCNE1', 'CASP2', 'CASP3', 'CASP6', 'CASP7', 'CASP9', 'MAPK12', 'PINK1', 'SLC6A3', 'TH', 'UBB', 'PRKN', 'CYCS', 'MAPK11', 'MAPK13', 'MIR34B', 'MIRLET7G', 'MIR34C', 'MIR26B', 'MIR195', 'MIR26A1', 'MIR26A2', 'MIR16-2', 'CCNE2', 'ATXN2', 'MIR503', 'SYT11', 'MIR370', 'MIR19A', 'MIR19B1', 'SEPTIN5', 'MIR132', 'SNCA', 'UCHL1', 'MIR338', 'UBE2J1', 'UBA1', 'UBA7', 'UBE2G1', 'UBE2G2', 'UBE2L3', 'MIR212', 'UBE2J2', 'MIR128-1', 'MIR30A', 'MIR431', 'MIR19B2', 'MIR1224', 'MIR4448', 'MIR10A', 'MIR136', 'MIR485', 'MIR873', 'MIR409', 'MIR433', 'MIR127', 'MIR30E', 'MIR1294', 'MIR128-2']}, {'KEID': 'https://identifiers.org/aop.events/1588', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/1549', 'WPtitle': 'Immune response to tuberculosis', 'gene': ['JAK2', 'TYK2', 'STAT1', 'JAK1', 'STAT2', 'SOCS1', 'IRF9', 'MX1', 'IFIT1', 'IFITM1', 'IFNGR1', 'PIAS1', 'IFNAR2', 'IFNGR2', 'IFNAR1', 'PSMB8', 'OAS1', 'IFI35', 'IFIT3', 'IRF1', 'TAP1', 'PTPN2', 'MED14']}, {'KEID': 'https://identifiers.org/aop.events/1549', 'WPtitle': 'Cytokines and inflammatory response', 'gene': ['IFNG', 'CXCL1', 'IL1B', 'CSF2', 'CSF1', 'IL13', 'IL12B', 'IL10', 'IL2', 'IL6', 'IL5', 'IL4', 'IL3', 'TNF', 'TGFB1', 'IL11', 'IL1A', 'IL15', 'CD4', 'IFNB1', 'HLA-DRB1', 'HLA-DRA', 'CXCL2', 'PDGFA', 'IL7', 'CSF3']}, {'KEID': 'https://identifiers.org/aop.events/1549', 'WPtitle': 'Cholestasis', 'gene': ['ATP8B1', 'HMGCR', 'LDLR', 'ABCC2', 'SCARB1', 'ABCG8', 'RXRA', 'TJP2', 'ABCG5', 'SLC22A1', 'ABCB4', 'NR1I3', 'SLC10A1', 'NR1H4', 'SLCO1A2', 'EPHX1', 'ABCC3', 'ABCB11', 'ABCC4']}, {'KEID': 'https://identifiers.org/aop.events/1549', 'WPtitle': 'Inflammatory response pathway', 'gene': ['TNFRSF1A', 'THBS3', 'THBS1', 'VTN', 'TNFRSF1B', 'CD40LG', 'CD40', 'CD86', 'CD80', 'CD28', 'ZAP70', 'IL5RA', 'IL5', 'IL4R', 'LAMB1', 'LAMA5', 'LCK', 'LAMC2', 'LAMC1', 'LAMB2', 'COL1A1', 'IFNG', 'FN1', 'COL3A1', 'COL1A2', 'IL4', 'IL2RG', 'IL2RB', 'IL2RA', 'IL2']}, {'KEID': 'https://identifiers.org/aop.events/357', 'WPtitle': 'Cholestasis', 'gene': ['ATP8B1', 'HMGCR', 'LDLR', 'ABCC2', 'SCARB1', 'ABCG8', 'RXRA', 'TJP2', 'ABCG5', 'SLC22A1', 'ABCB4', 'NR1I3', 'SLC10A1', 'NR1H4', 'SLCO1A2', 'EPHX1', 'ABCC3', 'ABCB11', 'ABCC4']}, {'KEID': 'https://identifiers.org/aop.events/1458', 'WPtitle': nan}, {'KEID': 'https://identifiers.org/aop.events/352', 'WPtitle': 'Oxidative stress response', 'gene': ['NOX3', 'NFIX', 'NOX1', 'MT1X', 'TXNRD2', 'NOX5', 'TXN2', 'CYBB', 'MAPK14', 'CYP1A1', 'FOS', 'MAOA', 'NFKB1', 'MAPK10', 'SP1', 'CAT', 'MGST1', 'GPX3', 'GPX1', 'GSTT2', 'GSR', 'SOD2', 'TXNRD1', 'SOD3', 'NOX4', 'JUNB', 'NFE2L2', 'NQO1', 'GCLC', 'HMOX1', 'SOD1', 'UGT1A6', 'XDH']}, {'KEID': 'https://identifiers.org/aop.events/352', 'WPtitle': 'Apoptosis modulation and signaling', 'gene': ['BIRC7', 'TNFRSF10A', 'BBC3', 'BIRC5', 'CASP10', 'CASP9', 'CASP7', 'DFFA', 'BMF', 'CAPNS1', 'APAF1', 'MAP3K14', 'JUN', 'PTPN13', 'PMAIP1', 'BCL2L11', 'PTRH2', 'TNFRSF10B', 'TNFSF10', 'MADD', 'HTRA2', 'SEPTIN4', 'BNIP3', 'BLK', 'BIRC3', 'BIRC2', 'BOK', 'BAX', 'BAK1', 'BCL2A1', 'BCL2', 'BCL2L2', 'BCL2L10', 'BCL2L1', 'BIK', 'BID', 'MIR29B2', 'MIR29B1', 'BAG3', 'BAD', 'TNFRSF10C', 'DIABLO', 'TNFRSF10D', 'CYCS', 'FADD', 'ENDOG', 'DFFB', 'FAS', 'IKBKB', 'HRK', 'FOS', 'FASLG', 'CASP8', 'CASP6', 'CASP3', 'CASP2', 'CDKN2A', 'DAXX', 'CRADD', 'CFLAR', 'PRKD1', 'PIDD1', 'XIAP', 'HSPA1A', 'NAIP', 'TRAF6', 'TRAF3', 'TRADD', 'TNFRSF25', 'TNFRSF1B', 'TNFRSF1A', 'NFKBIA', 'NFKB1', 'MYD88', 'MCL1', 'TOLLIP', 'TNFRSF6B', 'IRAK1', 'IL1R2', 'IL1R1', 'MAPK8', 'MAPK3', 'MAP3K5', 'CASP4', 'CASP1', 'AIFM2', 'RIPK1', 'PEA15', 'AIFM1', 'TP53']}, {'KEID': 'https://identifiers.org/aop.events/352', 'WPtitle': 'Apoptosis', 'gene': ['NFKBIB', 'NFKBIE', 'MIR29B1', 'MIR29B2', 'BCL2L11', 'CDKN2A', 'CHUK', 'BIRC2', 'BIRC3', 'XIAP', 'BIRC5', 'DFFA', 'DFFB', 'AKT1', 'BBC3', 'APAF1', 'FASLG', 'IRF3', 'IGF1', 'FAS', 'IKBKB', 'MCL1', 'MDM2', 'MAP3K1', 'MYC', 'NFKB1', 'IRF7', 'JUN', 'CYCS', 'MAPK10', 'DIABLO', 'BAD', 'BAK1', 'BAX', 'BCL2', 'PMAIP1', 'NFKBIA', 'PIK3R1', 'BID', 'MAP2K4', 'BOK', 'TNF', 'TNFRSF1A', 'BCL2L1', 'BCL2L2', 'CASP1', 'CASP2', 'CASP3', 'CASP4', 'CASP6', 'TNFRSF1B', 'TP53', 'TRAF3', 'IKBKG', 'TRADD', 'TNFRSF25', 'RIPK1', 'CRADD', 'HRK', 'CASP7', 'CASP8', 'CASP9', 'CASP10', 'TNFSF10', 'FADD', 'TNFRSF10B', 'CFLAR', 'LTA', 'RELA', 'IGF1R', 'TRAF1', 'TRAF2', 'TNFRSF21', 'BNIP3L', 'SCAF11', 'GZMB', 'HELLS', 'IGF2', 'IRF2', 'IRF4', 'PRF1', 'IRF6', 'TP73', 'TP63', 'MIR29A', 'IRF5', 'IRF1']}, {'KEID': 'https://identifiers.org/aop.events/352', 'WPtitle': 'BDNF-TrkB signaling', 'gene': ['EIF4EBP1', 'EEF2K', 'MTOR', 'MKNK1', 'DLG4', 'TRPC6', 'TRPC3', 'TSC2', 'MAPK1', 'PIK3CG', 'RHEB', 'RPS6KB1', 'RPS6KA1', 'CREB1', 'SOS1', 'SHC1', 'AKT1', 'HRAS', 'BDNF', 'TSC1', 'MAP2K1', 'NRAS', 'ARC', 'GAB1', 'GAB2', 'KRAS', 'NTRK2', 'PLCG1', 'ADCY1', 'GRIN1', 'GRB2', 'BRAF', 'HOMER1']}, {'KEID': 'https://identifiers.org/aop.events/352', 'WPtitle': 'Molecular pathway for oxidative stress', 'gene': []}]
Section 4: Calculation of N variable
In this section, variable N will be calculated per individual key event.
Step 10. First, the KEgenes dictionary is manipulated so that each gene is placed on an individual row. This requires the creation of a dataframe, adjustment of the column titles and explosion of the gene column.
first_dataframe=pd.DataFrame.from_dict(KE_genes_dictionary)
df5=df4.rename(columns={'name':'WPtitle'})
first_dataframe1=pd.merge(first_dataframe, df5, on='WPtitle')
second_dataframe=first_dataframe1.explode('gene')
second_dataframe1 = second_dataframe.drop(columns=['selected','AverageShortestPathLength','BetweennessCentrality','ClosenessCentrality','ClusteringCoefficient','group','type','Association type','CTL.Ext','CTL.Type','CTL.PathwayName','CTL.label','CTL.PathwayID','CTL.GeneName','CTL.GeneID','Eccentricity','EdgeCount','Indegree','IsSingleNode','NeighborhoodConnectivity','Outdegree','PartnerOfMultiEdgedNodePairs','SelfLoops','Stress','id','SUID'], axis=1)
second_dataframe1_reordered = second_dataframe.loc[:, ['KEID', 'WPtitle', 'shared name','gene']]
third_dataframe=second_dataframe1_reordered.rename(columns={'shared name':'ID'})
Step 11. The gene IDs that belong to gene symbols are added to complete the dataframe and merge this dataframe to the previous: third_dataframe. This will allow for a dataframe that contains all needed columns: KEID, WPtitle, WPID, gene symbol and gene ID.
df6= nodetable[nodetable['CTL.Type'] == 'gene']
df7=df6.rename(columns={'shared name':'gene'})
df8=df7.drop(columns=['name','selected','AverageShortestPathLength','BetweennessCentrality','ClosenessCentrality','ClusteringCoefficient','group','type','Association type','CTL.Ext','CTL.Type','CTL.PathwayName','CTL.label','CTL.PathwayID','CTL.GeneName','Eccentricity','EdgeCount','Indegree','IsSingleNode','NeighborhoodConnectivity','Outdegree','PartnerOfMultiEdgedNodePairs','SelfLoops','Stress','id','SUID'], axis=1)
mergeddataframe_gene=pd.merge(third_dataframe, df8, on='gene')
mergeddataframe_final=mergeddataframe_gene.rename(columns={'CTL.GeneID':'GENEID'})
mergeddataframe_final
KEID | WPtitle | ID | gene | GENEID | |
---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | IL25 | 64806 |
1 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | IL12A | 3592 |
2 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | CXCL8 | 3576 |
3 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | IL13 | 3596 |
4 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | CSF1 | 1435 |
... | ... | ... | ... | ... | ... |
20878 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | ADCY1 | 107 |
20879 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | GRIN1 | 2902 |
20880 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | GRB2 | 2885 |
20881 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | BRAF | 673 |
20882 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | HOMER1 | 9456 |
20883 rows × 5 columns
Step 12. The following for loop will be run for the calculation of the N variable. This for loop iterates over each row of the dataframe and will count the number of genes belonging to individual Key Events that are unique.
variable_N_dictionary_count= {}
for index, row in mergeddataframe_final.iterrows():
unique_KE = row['KEID']
gene = row['GENEID']
if unique_KE not in variable_N_dictionary_count:
variable_N_dictionary_count[unique_KE] = 1
else:
variable_N_dictionary_count[unique_KE] += 1
print("The total is: ")
print(variable_N_dictionary_count)
The total is:
{'https://identifiers.org/aop.events/486': 129, 'https://identifiers.org/aop.events/875': 169, 'https://identifiers.org/aop.events/2007': 184, 'https://identifiers.org/aop.events/1495': 253, 'https://identifiers.org/aop.events/105': 165, 'https://identifiers.org/aop.events/1816': 165, 'https://identifiers.org/aop.events/1668 ': 156, 'https://identifiers.org/aop.events/244 ': 417, 'https://identifiers.org/aop.events/1739': 8, 'https://identifiers.org/aop.events/1814 ': 251, 'https://identifiers.org/aop.events/1740': 4, 'https://identifiers.org/aop.events/888': 56, 'https://identifiers.org/aop.events/1574': 10, 'https://identifiers.org/aop.events/41': 275, 'https://identifiers.org/aop.events/1270': 72, 'https://identifiers.org/aop.events/1086': 144, 'https://identifiers.org/aop.events/1487 ': 19, 'https://identifiers.org/aop.events/1539': 170, 'https://identifiers.org/aop.events/201': 36, 'https://identifiers.org/aop.events/457': 584, 'https://identifiers.org/aop.events/55': 288, 'https://identifiers.org/aop.events/188': 17, 'https://identifiers.org/aop.events/618': 240, 'https://identifiers.org/aop.events/389': 36, 'https://identifiers.org/aop.events/177': 495, 'https://identifiers.org/aop.events/2013': 100, 'https://identifiers.org/aop.events/2006': 216, 'https://identifiers.org/aop.events/1497': 528, 'https://identifiers.org/aop.events/870': 31, 'https://identifiers.org/aop.events/1669': 400, 'https://identifiers.org/aop.events/1115': 34, 'https://identifiers.org/aop.events/202': 186, 'https://identifiers.org/aop.events/1917': 166, 'https://identifiers.org/aop.events/1633': 1056, 'https://identifiers.org/aop.events/1392': 102, 'https://identifiers.org/aop.events/1815': 58, 'https://identifiers.org/aop.events/386': 372, 'https://identifiers.org/aop.events/1944': 41, 'https://identifiers.org/aop.events/1582': 51, 'https://identifiers.org/aop.events/1896': 205, 'https://identifiers.org/aop.events/1172': 22, 'https://identifiers.org/aop.events/1496': 406, 'https://identifiers.org/aop.events/68': 64, 'https://identifiers.org/aop.events/1493': 812, 'https://identifiers.org/aop.events/265': 268, 'https://identifiers.org/aop.events/1817': 328, 'https://identifiers.org/aop.events/1819': 74, 'https://identifiers.org/aop.events/1750': 528, 'https://identifiers.org/aop.events/1901': 37, 'https://identifiers.org/aop.events/1848': 195, 'https://identifiers.org/aop.events/1847': 6, 'https://identifiers.org/aop.events/1748': 4, 'https://identifiers.org/aop.events/1365': 328, 'https://identifiers.org/aop.events/890': 34, 'https://identifiers.org/aop.events/1587': 57, 'https://identifiers.org/aop.events/1457': 19, 'https://identifiers.org/aop.events/1586': 31, 'https://identifiers.org/aop.events/149': 1056, 'https://identifiers.org/aop.events/1575': 328, 'https://identifiers.org/aop.events/1579': 353, 'https://identifiers.org/aop.events/87': 114, 'https://identifiers.org/aop.events/249': 34, 'https://identifiers.org/aop.events/288': 51, 'https://identifiers.org/aop.events/209': 617, 'https://identifiers.org/aop.events/1498': 224, 'https://identifiers.org/aop.events/1499': 26, 'https://identifiers.org/aop.events/1500': 260, 'https://identifiers.org/aop.events/1488': 184, 'https://identifiers.org/aop.events/1494': 74, 'https://identifiers.org/aop.events/52': 219, 'https://identifiers.org/aop.events/381': 199, 'https://identifiers.org/aop.events/484': 706, 'https://identifiers.org/aop.events/388': 169, 'https://identifiers.org/aop.events/1262': 328, 'https://identifiers.org/aop.events/1945': 1218, 'https://identifiers.org/aop.events/2009': 74, 'https://identifiers.org/aop.events/2012': 260, 'https://identifiers.org/aop.events/1770': 60, 'https://identifiers.org/aop.events/1818': 270, 'https://identifiers.org/aop.events/1738': 4, 'https://identifiers.org/aop.events/1752': 138, 'https://identifiers.org/aop.events/887': 116, 'https://identifiers.org/aop.events/1585': 35, 'https://identifiers.org/aop.events/214': 55, 'https://identifiers.org/aop.events/1271': 58, 'https://identifiers.org/aop.events/1087': 528, 'https://identifiers.org/aop.events/1538': 34, 'https://identifiers.org/aop.events/898': 328, 'https://identifiers.org/aop.events/195': 184, 'https://identifiers.org/aop.events/459': 132, 'https://identifiers.org/aop.events/341': 10, 'https://identifiers.org/aop.events/1670': 88, 'https://identifiers.org/aop.events/759': 82, 'https://identifiers.org/aop.events/1090': 459, 'https://identifiers.org/aop.events/344': 30, 'https://identifiers.org/aop.events/1841': 17, 'https://identifiers.org/aop.events/1820': 57, 'https://identifiers.org/aop.events/896': 82, 'https://identifiers.org/aop.events/1549': 101, 'https://identifiers.org/aop.events/357': 21, 'https://identifiers.org/aop.events/352': 398}
Step 13. The output of the dictionary will be converted into a dataframe and merged to the mergeddataframe_final dataframe to add the results into a separate column.
fourth_dataframe=pd.DataFrame.from_dict(variable_N_dictionary_count,orient='index')
df_reset = fourth_dataframe.reset_index()
df_reset.columns = ['KEID', 'N']
merged_dataframe= pd.merge(mergeddataframe_final, df_reset, on='KEID')
mergeddataframe=merged_dataframe.rename(columns={'ID':'WPID','gene':'Gene.Symbol'})
mergeddataframe
KEID | WPtitle | WPID | Gene.Symbol | GENEID | N | |
---|---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | IL25 | 64806 | 129 |
1 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | IL12A | 3592 | 129 |
2 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | CXCL8 | 3576 | 129 |
3 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | IL13 | 3596 | 129 |
4 | https://identifiers.org/aop.events/486 | Overview of proinflammatory and profibrotic me... | WP5095 | CSF1 | 1435 | 129 |
... | ... | ... | ... | ... | ... | ... |
20878 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | ADCY1 | 107 | 398 |
20879 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | GRIN1 | 2902 | 398 |
20880 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | GRB2 | 2885 | 398 |
20881 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | BRAF | 673 | 398 |
20882 | https://identifiers.org/aop.events/352 | BDNF-TrkB signaling | WP3676 | HOMER1 | 9456 | 398 |
20883 rows × 6 columns
Section 5. Comparison 1: Acrolein timepoint 2
In this section, Steps 14 to step 28 are repeated for comparison 2.
Section 5.1 Calculation of n variable
Comparison2_DEG= pd.read_csv("C:/Users/shaki/Downloads/DEG tables-all expressed genes/de_genes_ACR.24h.tsv",sep='\t',dtype={'GENE':'string'})
The_comparison2_DEG=Comparison2_DEG.dropna(subset=['GENE_SYMBOL'])
The_Comparison2_DEG=The_comparison2_DEG.drop_duplicates(subset=['GENE'])
Comparison_2_DEG= The_Comparison2_DEG[The_Comparison2_DEG['adj.P.Val'] < 0.05]
The_comparison_2_DEG=Comparison_2_DEG.copy()
Comparison2=The_comparison_2_DEG.rename(columns={'GENE':'GENEID'})
Comparison2['GENEID'] = Comparison2['GENEID'].astype(str)
Comparison_2=Comparison2.drop(columns=['SPOT_ID','COL','ROW','NAME','ACCESSION_STRING','CHROMOSOMAL_LOCATION','CYTOBAND','ORDER','ENSEMBL_ID','SPOT_ID.1','UNIGENE_ID','TIGR_ID','GO_ID','DESCRIPTION','SEQUENCE','CONTROL_TYPE','REFSEQ','GB_ACC'])
Comparison_2
ID | GENEID | GENE_SYMBOL | GENE_NAME | logFC | AveExpr | t | P.Value | adj.P.Val | B | |
---|---|---|---|---|---|---|---|---|---|---|
0 | 42685 | 3162 | HMOX1 | heme oxygenase (decycling) 1 | -1.179039 | 0.954675 | -6.285084 | 3.447616e-08 | 0.000253 | 6.360406 |
11 | 26200 | 23657 | SLC7A11 | solute carrier family 7, (cationic amino acid ... | -0.752090 | 0.640196 | -5.433205 | 9.494058e-07 | 0.003561 | 4.425625 |
15 | 4528 | 2495 | FTH1 | ferritin, heavy polypeptide 1 | 0.295169 | 0.276578 | 5.106348 | 3.264083e-06 | 0.009183 | 3.688642 |
17 | 36794 | 374946 | C1orf187 | chromosome 1 open reading frame 187 | -0.453613 | 0.062621 | -4.860757 | 8.109326e-06 | 0.020280 | 3.140473 |
18 | 27774 | 2298 | FOXD4 | forkhead box D4 | -0.474532 | 0.206407 | -4.787421 | 1.060632e-05 | 0.025129 | 2.978016 |
22 | 21063 | 89857 | KLHL6 | kelch-like 6 (Drosophila) | 0.748734 | -0.040346 | 4.660551 | 1.681000e-05 | 0.031843 | 2.698548 |
27 | 28950 | 201161 | CENPV | centromere protein V | 0.234981 | 0.018625 | 4.523276 | 2.750745e-05 | 0.042802 | 2.398681 |
30 | 7970 | 84981 | C17orf91 | chromosome 17 open reading frame 91 | -0.502606 | 0.170289 | -4.482172 | 3.183893e-05 | 0.046233 | 2.309453 |
31 | 18739 | 55089 | SLC38A4 | solute carrier family 38, member 4 | -0.293797 | -0.025377 | -4.464863 | 3.385527e-05 | 0.047625 | 2.271960 |
32 | 21386 | 1543 | CYP1A1 | cytochrome P450, family 1, subfamily A, polype... | 0.234158 | 0.184573 | 4.450278 | 3.565014e-05 | 0.047916 | 2.240408 |
Step 14. The results of the DEG table are next integrated into the mergeddataframe dataframe. This is followed by adjustment of the dataframe columns to remove non-relevant columns.
merged_dataframe_C2= pd.merge(mergeddataframe,Comparison_2, on='GENEID')
Step 15. The following for loop for the key events is run to retrieve the n variable. It is comparable to the for loop of N, but adds a condition to check for significance of genes by p adjusted value being smaller than 0.05.
variable_n_dictionary_count2= {}
for index, row in merged_dataframe_C2.iterrows():
unique_KE = row['KEID']
gene_expression_value = row['adj.P.Val']
if gene_expression_value < 0.05:
if unique_KE not in variable_n_dictionary_count2:
variable_n_dictionary_count2[unique_KE] = 1
else:
variable_n_dictionary_count2[unique_KE] += 1
print("The total number of significant genes: ")
print(variable_n_dictionary_count2)
The total number of significant genes:
{'https://identifiers.org/aop.events/244 ': 5, 'https://identifiers.org/aop.events/41': 5, 'https://identifiers.org/aop.events/1115': 2, 'https://identifiers.org/aop.events/1917': 5, 'https://identifiers.org/aop.events/1392': 6, 'https://identifiers.org/aop.events/265': 2, 'https://identifiers.org/aop.events/890': 2, 'https://identifiers.org/aop.events/249': 2, 'https://identifiers.org/aop.events/209': 6, 'https://identifiers.org/aop.events/1538': 2, 'https://identifiers.org/aop.events/352': 2}
Step 16. The output of the n variable dictionary is saved as a dataframe and integrated as a separate column into a dataframe.
n_variable_dataframe2=pd.DataFrame.from_dict(variable_n_dictionary_count2,orient='index')
n_variable_dataframe2
0 | |
---|---|
https://identifiers.org/aop.events/244 | 5 |
https://identifiers.org/aop.events/41 | 5 |
https://identifiers.org/aop.events/1115 | 2 |
https://identifiers.org/aop.events/1917 | 5 |
https://identifiers.org/aop.events/1392 | 6 |
https://identifiers.org/aop.events/265 | 2 |
https://identifiers.org/aop.events/890 | 2 |
https://identifiers.org/aop.events/249 | 2 |
https://identifiers.org/aop.events/209 | 6 |
https://identifiers.org/aop.events/1538 | 2 |
https://identifiers.org/aop.events/352 | 2 |
n_variable_dataframe_reset2 = n_variable_dataframe2.reset_index()
n_variable_dataframe_reset2.columns = ['KEID', 'n']
n_variable_dataframe_reset2
KEID | n | |
---|---|---|
0 | https://identifiers.org/aop.events/244 | 5 |
1 | https://identifiers.org/aop.events/41 | 5 |
2 | https://identifiers.org/aop.events/1115 | 2 |
3 | https://identifiers.org/aop.events/1917 | 5 |
4 | https://identifiers.org/aop.events/1392 | 6 |
5 | https://identifiers.org/aop.events/265 | 2 |
6 | https://identifiers.org/aop.events/890 | 2 |
7 | https://identifiers.org/aop.events/249 | 2 |
8 | https://identifiers.org/aop.events/209 | 6 |
9 | https://identifiers.org/aop.events/1538 | 2 |
10 | https://identifiers.org/aop.events/352 | 2 |
merged_dataframe3= pd.merge(mergeddataframe, n_variable_dataframe_reset2, on='KEID')
Section 6.2. Calculation of variable B and variable b.
In this section, variable B and variable b are calculated.
Step 17. Variable B is calculated by taking the length of the dataframe which includes all genes in 1 DEG table.
B=len(The_Comparison2_DEG.index)
B
19751
Step 18. Variable b is calculated by taking the length of the dataframe which includes all genes in 1 DEG table with the condition for significance.
Comparison2_DEG_filtered=The_Comparison2_DEG[The_Comparison2_DEG['adj.P.Val'] < 0.05]
b=len(Comparison2_DEG_filtered)
b
10
Section 6.3. Calculation of enrichment score and hypergeometric p-value
In this section, the enrichment score and hypergeometric p-value will be calculated.
Step 19. The final dataframe will be created that contains the KEID and the four variables: variable N, variable n, variable B and variable b.
Final_dataframe_ES= merged_dataframe3.loc[:, ['KEID','N','n']]
Final_dataframe_ES['B']=pd.Series([19751 for x in range(len(Final_dataframe_ES.index))])
Final_dataframe_ES['b']=pd.Series([10 for x in range(len(Final_dataframe_ES.index))])
Final_Dataframe_ES=Final_dataframe_ES.drop_duplicates(subset=['KEID'],keep='first')
Final_Dataframe_ES.reset_index(drop=True,inplace=True)
Copy_Final_Dataframe_ES=Final_Dataframe_ES.copy()
Step 20. The follow for loop will be used to calculate the enrichment score for individual key events and the results will be saved as a separate column into the dataframe.
def calculate_Enrichment_Score(row):
return f"{(row['n']/row['N'])/(row['b']/row['B'])}"
Copy_Final_Dataframe_ES.loc[:,'Enrichmentscore']= Copy_Final_Dataframe_ES.apply(calculate_Enrichment_Score,axis=1)
Copy_Final_Dataframe_ES
KEID | N | n | B | b | Enrichmentscore | |
---|---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/244 | 417 | 5 | 19751 | 10 | 23.682254196642685 |
1 | https://identifiers.org/aop.events/41 | 275 | 5 | 19751 | 10 | 35.91090909090909 |
2 | https://identifiers.org/aop.events/1115 | 34 | 2 | 19751 | 10 | 116.18235294117648 |
3 | https://identifiers.org/aop.events/1917 | 166 | 5 | 19751 | 10 | 59.49096385542169 |
4 | https://identifiers.org/aop.events/1392 | 102 | 6 | 19751 | 10 | 116.18235294117648 |
5 | https://identifiers.org/aop.events/265 | 268 | 2 | 19751 | 10 | 14.73955223880597 |
6 | https://identifiers.org/aop.events/890 | 34 | 2 | 19751 | 10 | 116.18235294117648 |
7 | https://identifiers.org/aop.events/249 | 34 | 2 | 19751 | 10 | 116.18235294117648 |
8 | https://identifiers.org/aop.events/209 | 617 | 6 | 19751 | 10 | 19.206807131280392 |
9 | https://identifiers.org/aop.events/1538 | 34 | 2 | 19751 | 10 | 116.18235294117648 |
10 | https://identifiers.org/aop.events/352 | 398 | 2 | 19751 | 10 | 9.925125628140703 |
Step 21. The following for loop will be used to calculate the hypergeometric p-value for individual Key Events and save the result as a separate column into the dataframe. This requires some in between steps for manipulation of the dataframe.
p_value_dataframe2=[]
for index, row in Copy_Final_Dataframe_ES.iterrows():
M = row['B']
n = row['b']
N = row['N']
k = row['n']
hpd = ss.hypergeom(M, n, N)
p = hpd.pmf(k)
p_value_dataframe2.append(p)
Hypergeometricpvalue_dataframe2=pd.DataFrame(p_value_dataframe2)
Hypergeometricpvalue_dataframe2.columns= ['Hypergeometric p-value']
Hypergeometricpvalue_dataframe2
Hypergeometric p-value | |
---|---|
0 | 9.292040e-07 |
1 | 1.187297e-07 |
2 | 1.277656e-04 |
3 | 9.550671e-09 |
4 | 3.365904e-12 |
5 | 7.405932e-03 |
6 | 1.277656e-04 |
7 | 1.277656e-04 |
8 | 1.680839e-07 |
9 | 1.277656e-04 |
10 | 1.550040e-02 |
merged_finaltable=pd.concat([Copy_Final_Dataframe_ES,Hypergeometricpvalue_dataframe2],axis=1)
Section 6.4. Filtering the results for significant KEs
In this section, the results will be filtered to only include significant KEs. Significant KEs have an enrichment score above 1 and a hypergeometric p-value below 0.05.
Step 22. Lastly, we filter the results to showcase the significant KEs for comparison 2.
filteredversion_C2= merged_finaltable[(merged_finaltable['Enrichmentscore']>str(1))& (merged_finaltable['Hypergeometric p-value'] < 0.05)]
filteredversion_C2
KEID | N | n | B | b | Enrichmentscore | Hypergeometric p-value | |
---|---|---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/244 | 417 | 5 | 19751 | 10 | 23.682254196642685 | 9.292040e-07 |
1 | https://identifiers.org/aop.events/41 | 275 | 5 | 19751 | 10 | 35.91090909090909 | 1.187297e-07 |
2 | https://identifiers.org/aop.events/1115 | 34 | 2 | 19751 | 10 | 116.18235294117648 | 1.277656e-04 |
3 | https://identifiers.org/aop.events/1917 | 166 | 5 | 19751 | 10 | 59.49096385542169 | 9.550671e-09 |
4 | https://identifiers.org/aop.events/1392 | 102 | 6 | 19751 | 10 | 116.18235294117648 | 3.365904e-12 |
5 | https://identifiers.org/aop.events/265 | 268 | 2 | 19751 | 10 | 14.73955223880597 | 7.405932e-03 |
6 | https://identifiers.org/aop.events/890 | 34 | 2 | 19751 | 10 | 116.18235294117648 | 1.277656e-04 |
7 | https://identifiers.org/aop.events/249 | 34 | 2 | 19751 | 10 | 116.18235294117648 | 1.277656e-04 |
8 | https://identifiers.org/aop.events/209 | 617 | 6 | 19751 | 10 | 19.206807131280392 | 1.680839e-07 |
9 | https://identifiers.org/aop.events/1538 | 34 | 2 | 19751 | 10 | 116.18235294117648 | 1.277656e-04 |
10 | https://identifiers.org/aop.events/352 | 398 | 2 | 19751 | 10 | 9.925125628140703 | 1.550040e-02 |
Section 6.5. Calculation of percent gene overlap to ORA
Section 6.5.1 Creation of the significant KEs table
In this section, you merge the dataframes to retrieve the genes connected to only the significant KEs.
Step 23. The significant KE table is created using the significan KEs from the previous merggeddataframe_final.
mergeddataframe_final2=mergeddataframe_final.copy()
mergeddataframe_final2['KEID'] = mergeddataframe_final2['KEID'].str.strip()
significantKEID_genetable2=mergeddataframe_final2[(mergeddataframe_final2['KEID'] == 'https://identifiers.org/aop.events/244')| (mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/41') |(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1115')| (mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1917')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1392') |(mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/265')|(mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/890')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/249')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/209')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/1538')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/352')]
significantKEIDgenetable2=significantKEID_genetable2.drop(columns={'WPtitle','ID'})
significantKEIDgenetable2
KEID | gene | GENEID | |
---|---|---|---|
1221 | https://identifiers.org/aop.events/244 | MBTPS1 | 8720 |
1222 | https://identifiers.org/aop.events/244 | ATF4 | 468 |
1223 | https://identifiers.org/aop.events/244 | ATF4 | 100089902 |
1224 | https://identifiers.org/aop.events/244 | ATF4 | 100144302 |
1225 | https://identifiers.org/aop.events/244 | MBTPS2 | 51360 |
... | ... | ... | ... |
20878 | https://identifiers.org/aop.events/352 | ADCY1 | 107 |
20879 | https://identifiers.org/aop.events/352 | GRIN1 | 2902 |
20880 | https://identifiers.org/aop.events/352 | GRB2 | 2885 |
20881 | https://identifiers.org/aop.events/352 | BRAF | 673 |
20882 | https://identifiers.org/aop.events/352 | HOMER1 | 9456 |
2379 rows × 3 columns
Section 6.5.2 Significant ORA pathway table plus splitting
In this section, the significant ORA pathway table is created.
Step 24. The significant ORA pathway table is created using the significant enriched patwhays identified from the ORA analysis. This requires data manipulation to restructure the table in a way that the individual genes for the enriched pathways are placed on individual rows.
datafile_ORA2 = pd.read_csv("C:/Users/shaki/Downloads/GSE44729_ORApathwaytable/Comparison 2-ACR timepoint 2.txt", sep='\t')
datafileORA2=pd.DataFrame(datafile_ORA2)
filtereddatafileORA_2=datafileORA2[datafileORA2['Adjusted P-value'] < 0.05]
Gene_set | Term | P-value | Adjusted P-value | Old P-value | Old adjusted P-value | Odds Ratio | Combined Score | Genes | |
---|---|---|---|---|---|---|---|---|---|
0 | WikiPathways_2024_Human | Transcriptional Activation By NRF2 In Response... | 0.000007 | 0.000217 | 0 | 0 | 822.12500 | 9759.6900 | HMOX1;SLC7A11 |
1 | WikiPathways_2024_Human | NRF2 ARE Regulation WP4357 | 0.000018 | 0.000275 | 0 | 0 | 493.07500 | 5394.6400 | HMOX1;SLC7A11 |
2 | WikiPathways_2024_Human | Antiviral And Anti-Inflam Effects Of Nrf2 On S... | 0.000029 | 0.000299 | 0 | 0 | 379.17310 | 3962.0320 | HMOX1;SLC7A11 |
3 | WikiPathways_2024_Human | Oxidative Stress Response WP408 | 0.000040 | 0.000313 | 0 | 0 | 317.93550 | 3216.1110 | CYP1A1;HMOX1 |
4 | WikiPathways_2024_Human | Nuclear Receptors Meta Pathway WP2882 | 0.000068 | 0.000420 | 0 | 0 | 65.25168 | 626.3850 | CYP1A1;HMOX1;SLC7A11 |
5 | WikiPathways_2024_Human | Ferroptosis WP4313 | 0.000149 | 0.000770 | 0 | 0 | 161.32790 | 1421.5610 | HMOX1;SLC7A11 |
6 | WikiPathways_2024_Human | NRF2 Pathway WP2884 | 0.000673 | 0.002982 | 0 | 0 | 74.28409 | 542.5193 | HMOX1;SLC7A11 |
7 | WikiPathways_2024_Human | Amino Acid Metabolism In Triple Negative Breas... | 0.002125 | 0.007320 | 0 | 0 | 657.90000 | 4048.6940 | SLC7A11 |
8 | WikiPathways_2024_Human | mRNA Protein And Metabolite Inducation Pathway... | 0.002125 | 0.007320 | 0 | 0 | 657.90000 | 4048.6940 | SLC7A11 |
9 | WikiPathways_2024_Human | Benzo A Pyrene Metabolism WP696 | 0.002428 | 0.007528 | 0 | 0 | 563.88570 | 3394.9080 | CYP1A1 |
10 | WikiPathways_2024_Human | IL10 Anti Inflammatory Signaling WP4495 | 0.003641 | 0.009403 | 0 | 0 | 358.76360 | 2014.6730 | HMOX1 |
11 | WikiPathways_2024_Human | Estrogen Receptor Pathway WP2881 | 0.003944 | 0.009403 | 0 | 0 | 328.85000 | 1820.4090 | CYP1A1 |
12 | WikiPathways_2024_Human | Fatty Acid Omega Oxidation WP206 | 0.004246 | 0.009403 | 0 | 0 | 303.53850 | 1657.8360 | CYP1A1 |
13 | WikiPathways_2024_Human | Estrogen Metabolism WP697 | 0.004246 | 0.009403 | 0 | 0 | 303.53850 | 1657.8360 | CYP1A1 |
14 | WikiPathways_2024_Human | Overview Of Nanoparticle Effects WP3287 | 0.005457 | 0.011159 | 0 | 0 | 232.07060 | 1209.2950 | HMOX1 |
15 | WikiPathways_2024_Human | Tamoxifen Metabolism WP691 | 0.005759 | 0.011159 | 0 | 0 | 219.16670 | 1130.2320 | CYP1A1 |
16 | WikiPathways_2024_Human | Photodynamic Therapy Induced NFE2L2 NRF2 Survi... | 0.006968 | 0.012707 | 0 | 0 | 179.28180 | 890.3855 | HMOX1 |
17 | WikiPathways_2024_Human | Cannabinoid Receptor Signaling WP3869 | 0.008779 | 0.014816 | 0 | 0 | 140.82140 | 666.8399 | CYP1A1 |
18 | WikiPathways_2024_Human | Tryptophan Metabolism WP465 | 0.009081 | 0.014816 | 0 | 0 | 135.95860 | 639.2207 | CYP1A1 |
19 | WikiPathways_2024_Human | Melatonin Metabolism And Effects WP3298 | 0.010286 | 0.015944 | 0 | 0 | 119.45450 | 546.7346 | CYP1A1 |
20 | WikiPathways_2024_Human | Aryl Hydrocarbon Receptor Pathway WP2873 | 0.012393 | 0.018295 | 0 | 0 | 98.51500 | 432.5399 | CYP1A1 |
21 | WikiPathways_2024_Human | Aryl Hydrocarbon Receptor Pathway WP2586 | 0.013596 | 0.019157 | 0 | 0 | 89.54091 | 384.8481 | CYP1A1 |
22 | WikiPathways_2024_Human | Lung Fibrosis WP3624 | 0.017195 | 0.022597 | 0 | 0 | 70.31071 | 285.6825 | HMOX1 |
23 | WikiPathways_2024_Human | Oxidation By Cytochrome P450 WP43 | 0.017494 | 0.022597 | 0 | 0 | 69.07368 | 279.4637 | CYP1A1 |
24 | WikiPathways_2024_Human | Urotensin II Mediated Signaling WP5158 | 0.020485 | 0.025401 | 0 | 0 | 58.73433 | 228.3637 | HMOX1 |
25 | WikiPathways_2024_Human | P53 Transcriptional Gene Network WP4963 | 0.024658 | 0.029400 | 0 | 0 | 48.54815 | 179.7562 | SLC7A11 |
26 | WikiPathways_2024_Human | CAMKK2 Pathway WP4874 | 0.031483 | 0.036147 | 0 | 0 | 37.76731 | 130.6109 | HMOX1 |
27 | WikiPathways_2024_Human | Male Infertility WP4673 | 0.039150 | 0.043345 | 0 | 0 | 30.17385 | 97.7740 | CYP1A1 |
dropped_datafileORA_df2=filtereddatafileORA_2.drop(['Adjusted P-value','Odds Ratio','Old P-value','Gene_set','P-value','Old adjusted P-value','Combined Score'],axis=1)
droppeddatafileORAdf2=dropped_datafileORA_df2.copy()
droppeddatafileORAdf2['Genes']= droppeddatafileORAdf2['Genes'].replace({';':','},regex=True)
df2_ORApathwaytable=droppeddatafileORAdf2.copy()
df2_ORApathwaytable['Genes'] = df2_ORApathwaytable['Genes'].astype(str)
df2_ORApathwaytable['Genes'] = df2_ORApathwaytable['Genes'].str.split(',')
exploded_df2_ORApathwaytable = df2_ORApathwaytable.explode('Genes', ignore_index=True)
Section 6.5.3 For loop to get overlapping genes
In this section, the number of overlapping genes between the significant enrichment score-based Key Events and enriched pathways from ORA are calculated.
Step 25. Next, two sets are created by converting the significant KE table and ORA pathway table into dictionaries where the values of the genes are grouped together per key. This is followed by running a for loop to calculate the number of overlapping genes along with the symbols.
ORA_gene_sets2 = exploded_df2_ORApathwaytable.groupby('Term')['Genes'].apply(set).to_dict()
SignificantKE_gene_sets2 = significantKEIDgenetable2.groupby('KEID')['gene'].apply(set).to_dict()
overlapping_genes_betweenORA_and_significantKEs2 = {}
for term, ORA_genes in ORA_gene_sets2.items():
for KEID, KEID_genes in SignificantKE_gene_sets2.items():
overlap = ORA_genes.intersection(KEID_genes)
print(f"{term} x {KEID}: {len(overlap)} overlaps")
overlapping_genes_betweenORA_and_significantKEs2[(term, KEID)] = {
'overlapping genes': overlap,
'number of genes that overlap': len(overlap)
}
if overlapping_genes_betweenORA_and_significantKEs2:
print("\ntitle of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:")
for (term, KEID), result in overlapping_genes_betweenORA_and_significantKEs2.items():
print(f"Term: {term}, KEID: {KEID}, Title of overlapping gene(s): {result['overlapping genes']}, number: {result['number of genes that overlap']}")
else:
print("No overlapping genes")
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1115: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1392: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1538: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1917: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/209: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/244: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/249: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/265: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/352: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/41: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/890: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1115: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1392: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1538: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1917: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/209: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/244: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/249: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/265: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/352: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/41: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/890: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/1115: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/1392: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/1538: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/1917: 0 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/209: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/244: 0 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/249: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/265: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/352: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/41: 0 overlaps
Aryl Hydrocarbon Receptor Pathway WP2586 x https://identifiers.org/aop.events/890: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/1115: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/1392: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/1538: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/1917: 0 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/209: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/244: 0 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/249: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/265: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/352: 1 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/41: 0 overlaps
Aryl Hydrocarbon Receptor Pathway WP2873 x https://identifiers.org/aop.events/890: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/1115: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/1392: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/1538: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/1917: 0 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/209: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/244: 0 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/249: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/265: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/352: 1 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/41: 0 overlaps
Benzo A Pyrene Metabolism WP696 x https://identifiers.org/aop.events/890: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/1115: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/1392: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/1538: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/1917: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/209: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/244: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/249: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/265: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/352: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/41: 1 overlaps
CAMKK2 Pathway WP4874 x https://identifiers.org/aop.events/890: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/1115: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/1392: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/1538: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/1917: 0 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/209: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/244: 0 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/249: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/265: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/352: 1 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/41: 0 overlaps
Cannabinoid Receptor Signaling WP3869 x https://identifiers.org/aop.events/890: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/1115: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/1392: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/1538: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/1917: 0 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/209: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/244: 0 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/249: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/265: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/352: 1 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/41: 0 overlaps
Estrogen Metabolism WP697 x https://identifiers.org/aop.events/890: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/1115: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/1392: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/1538: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/1917: 0 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/209: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/244: 0 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/249: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/265: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/352: 1 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/41: 0 overlaps
Estrogen Receptor Pathway WP2881 x https://identifiers.org/aop.events/890: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/1115: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/1392: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/1538: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/1917: 0 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/209: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/244: 0 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/249: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/265: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/352: 1 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/41: 0 overlaps
Fatty Acid Omega Oxidation WP206 x https://identifiers.org/aop.events/890: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1115: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1392: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1538: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1917: 2 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/209: 2 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/244: 2 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/249: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/265: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/352: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/41: 2 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/890: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/1115: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/1392: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/1538: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/1917: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/209: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/244: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/249: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/265: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/352: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/41: 1 overlaps
IL10 Anti Inflammatory Signaling WP4495 x https://identifiers.org/aop.events/890: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/1115: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/1392: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/1538: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/1917: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/209: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/244: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/249: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/265: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/352: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/41: 1 overlaps
Lung Fibrosis WP3624 x https://identifiers.org/aop.events/890: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/1115: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/1392: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/1538: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/1917: 0 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/209: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/244: 0 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/249: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/265: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/352: 1 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/41: 0 overlaps
Male Infertility WP4673 x https://identifiers.org/aop.events/890: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/1115: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/1392: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/1538: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/1917: 0 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/209: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/244: 0 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/249: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/265: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/352: 1 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/41: 0 overlaps
Melatonin Metabolism And Effects WP3298 x https://identifiers.org/aop.events/890: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1115: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1392: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1538: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1917: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/209: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/244: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/249: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/265: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/352: 1 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/41: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/890: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1115: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1392: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1538: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1917: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/209: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/244: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/249: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/265: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/352: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/41: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/890: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1115: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1392: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1538: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1917: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/209: 3 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/244: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/249: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/265: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/352: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/41: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/890: 2 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/1115: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/1392: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/1538: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/1917: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/209: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/244: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/249: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/265: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/352: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/41: 1 overlaps
Overview Of Nanoparticle Effects WP3287 x https://identifiers.org/aop.events/890: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/1115: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/1392: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/1538: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/1917: 0 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/209: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/244: 0 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/249: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/265: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/352: 1 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/41: 0 overlaps
Oxidation By Cytochrome P450 WP43 x https://identifiers.org/aop.events/890: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1115: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1392: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1538: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1917: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/209: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/244: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/249: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/265: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/352: 2 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/41: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/890: 2 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1115: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1392: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1538: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1917: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/209: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/244: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/249: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/265: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/352: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/41: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/890: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1115: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1392: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1538: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1917: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/209: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/244: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/249: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/265: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/352: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/41: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/890: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/1115: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/1392: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/1538: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/1917: 0 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/209: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/244: 0 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/249: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/265: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/352: 1 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/41: 0 overlaps
Tamoxifen Metabolism WP691 x https://identifiers.org/aop.events/890: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1115: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1392: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1538: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1917: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/209: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/244: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/249: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/265: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/352: 1 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/41: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/890: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/1115: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/1392: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/1538: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/1917: 0 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/209: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/244: 0 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/249: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/265: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/352: 1 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/41: 0 overlaps
Tryptophan Metabolism WP465 x https://identifiers.org/aop.events/890: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/1115: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/1392: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/1538: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/1917: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/209: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/244: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/249: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/265: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/352: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/41: 1 overlaps
Urotensin II Mediated Signaling WP5158 x https://identifiers.org/aop.events/890: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1115: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1392: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1538: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1917: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/209: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/244: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/249: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/265: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/352: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/41: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/890: 0 overlaps
title of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Aryl Hydrocarbon Receptor Pathway WP2586, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Aryl Hydrocarbon Receptor Pathway WP2873, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Benzo A Pyrene Metabolism WP696, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: CAMKK2 Pathway WP4874, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Cannabinoid Receptor Signaling WP3869, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Metabolism WP697, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Receptor Pathway WP2881, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Fatty Acid Omega Oxidation WP206, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: IL10 Anti Inflammatory Signaling WP4495, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Lung Fibrosis WP3624, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Male Infertility WP4673, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Melatonin Metabolism And Effects WP3298, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1', 'HMOX1', 'SLC7A11'}, number: 3
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Overview Of Nanoparticle Effects WP3287, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Oxidation By Cytochrome P450 WP43, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1', 'HMOX1'}, number: 2
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Tamoxifen Metabolism WP691, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Tryptophan Metabolism WP465, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'CYP1A1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Urotensin II Mediated Signaling WP5158, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Section 6.5.4 Tabulation gene overlap
In this section, a table is created that contains the number of overlapping genes and number of total genes in preparation for section 6.5.5.
final_geneoverlaptable_C2=pd.DataFrame.from_dict(overlapping_genes_betweenORA_and_significantKEs2,orient='index')
Section 6.5.5 Percent overlap calculation
In this section, the percent overlap for the genesets are calculated.
Step 26. Lastly, the percent overlap is calculated and add the result as a column to the dataframe. This is first done by running a for loop to calculate the total number of genes belonging to the enriched pathways of ORA.
variable_count2= {}
for index, row in exploded_df2_ORApathwaytable.iterrows():
unique_KE = row['Term']
gene_expression_value = row['Genes']
if unique_KE not in variable_count2:
variable_count2[unique_KE] = 1
else:
variable_count2[unique_KE] += 1
print("The total number of genes: ")
print(variable_count2)
The total number of genes:
{'Transcriptional Activation By NRF2 In Response To Phytochemicals WP3': 2, 'NRF2 ARE Regulation WP4357': 2, 'Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113': 2, 'Oxidative Stress Response WP408': 2, 'Nuclear Receptors Meta Pathway WP2882': 3, 'Ferroptosis WP4313': 2, 'NRF2 Pathway WP2884': 2, 'Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213': 1, 'mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953': 1, 'Benzo A Pyrene Metabolism WP696': 1, 'IL10 Anti Inflammatory Signaling WP4495': 1, 'Estrogen Receptor Pathway WP2881': 1, 'Fatty Acid Omega Oxidation WP206': 1, 'Estrogen Metabolism WP697': 1, 'Overview Of Nanoparticle Effects WP3287': 1, 'Tamoxifen Metabolism WP691': 1, 'Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612': 1, 'Cannabinoid Receptor Signaling WP3869': 1, 'Tryptophan Metabolism WP465': 1, 'Melatonin Metabolism And Effects WP3298': 1, 'Aryl Hydrocarbon Receptor Pathway WP2873': 1, 'Aryl Hydrocarbon Receptor Pathway WP2586': 1, 'Lung Fibrosis WP3624': 1, 'Oxidation By Cytochrome P450 WP43': 1, 'Urotensin II Mediated Signaling WP5158': 1, 'P53 Transcriptional Gene Network WP4963': 1, 'CAMKK2 Pathway WP4874': 1, 'Male Infertility WP4673': 1}
Step 27. The result is converted into a dataframe and added to the final dataframe. This is followed by some data manipulation prior to calculation of gene set overlap.
variable_count_df2=pd.DataFrame.from_dict(variable_count2,orient='index')
reset_variable_count_df2 = variable_count_df2.reset_index()
reset_variable_count_df2.columns = ['Term', 'Total number of genes']
Genesetoverlaptable_C2=final_geneoverlaptable_C2.reset_index(level=[1])
Genesetoverlaptable_C2.reset_index(inplace=True)
Genesetoverlaptable_C2.columns= ['Term','KEID','overlapping genes','number of genes that overlap']
tabulation_C2=pd.merge(reset_variable_count_df2,Genesetoverlaptable_C2, on='Term')
def calculate_Genesetoverlap_Score(row):
return f"{(row['number of genes that overlap']/row['Total number of genes'])*100}"
tabulation_C2.loc[:,'Percent geneset overlap']= tabulation_C2.apply(calculate_Genesetoverlap_Score, axis=1)
tabulation_C2
Term | Total number of genes | KEID | overlapping genes | number of genes that overlap | Percent geneset overlap | |
---|---|---|---|---|---|---|
0 | Transcriptional Activation By NRF2 In Response... | 2 | https://identifiers.org/aop.events/1115 | {HMOX1} | 1 | 50.0 |
1 | Transcriptional Activation By NRF2 In Response... | 2 | https://identifiers.org/aop.events/1392 | {HMOX1} | 1 | 50.0 |
2 | Transcriptional Activation By NRF2 In Response... | 2 | https://identifiers.org/aop.events/1538 | {HMOX1} | 1 | 50.0 |
3 | Transcriptional Activation By NRF2 In Response... | 2 | https://identifiers.org/aop.events/1917 | {HMOX1, SLC7A11} | 2 | 100.0 |
4 | Transcriptional Activation By NRF2 In Response... | 2 | https://identifiers.org/aop.events/209 | {HMOX1, SLC7A11} | 2 | 100.0 |
... | ... | ... | ... | ... | ... | ... |
303 | Male Infertility WP4673 | 1 | https://identifiers.org/aop.events/249 | {CYP1A1} | 1 | 100.0 |
304 | Male Infertility WP4673 | 1 | https://identifiers.org/aop.events/265 | {CYP1A1} | 1 | 100.0 |
305 | Male Infertility WP4673 | 1 | https://identifiers.org/aop.events/352 | {CYP1A1} | 1 | 100.0 |
306 | Male Infertility WP4673 | 1 | https://identifiers.org/aop.events/41 | {} | 0 | 0.0 |
307 | Male Infertility WP4673 | 1 | https://identifiers.org/aop.events/890 | {CYP1A1} | 1 | 100.0 |
308 rows × 6 columns
Section 7. Comparison 3: Chloropicrin timepoint 1
Section 7.1 Calculation of n variable
In this section, variable n will be calculated for the comparison 3.
Step 28. The table containing the differential expressed genes for Bisphenol A 1uM to control is loaded with the filter for significance.
Comparison3_DEG= pd.read_csv("C:/Users/shaki/Downloads/DEG tables-all expressed genes/de_genes_CP.10h.tsv",sep='\t',dtype={'GENE':'string'})
The_comparison3_DEG=Comparison3_DEG.dropna(subset=['GENE_SYMBOL'])
The_Comparison3_DEG=The_comparison3_DEG.drop_duplicates(subset=['GENE'])
Comparison_3_DEG= The_Comparison3_DEG[The_Comparison3_DEG['adj.P.Val'] < 0.05]
The_comparison_3_DEG=Comparison_3_DEG.copy()
Comparison3=The_comparison_3_DEG.rename(columns={'GENE':'GENEID'})
Comparison3['GENEID'] = Comparison3['GENEID'].astype(str)
Comparison_3=Comparison3.drop(columns=['SPOT_ID','COL','ROW','NAME','ACCESSION_STRING','CHROMOSOMAL_LOCATION','CYTOBAND','ORDER','ENSEMBL_ID','SPOT_ID.1','UNIGENE_ID','TIGR_ID','GO_ID','DESCRIPTION','SEQUENCE','CONTROL_TYPE','REFSEQ','GB_ACC'])
Comparison_3
ID | GENEID | GENE_SYMBOL | GENE_NAME | logFC | AveExpr | t | P.Value | adj.P.Val | B | |
---|---|---|---|---|---|---|---|---|---|---|
0 | 26605 | 1960 | EGR3 | early growth response 3 | -0.863408 | 0.094340 | -7.955544 | 4.246899e-11 | 0.000002 | 10.081124 |
2 | 41618 | 6434 | SFRS10 | splicing factor, arginine/serine-rich 10 (tran... | -0.232531 | 0.026262 | -6.309106 | 3.135061e-08 | 0.000470 | 6.437660 |
4 | 42522 | 100129449 | LOC100129449 | PRO2055 | -0.128508 | -0.004284 | -5.709801 | 3.279151e-07 | 0.002750 | 5.072106 |
5 | 23385 | 3214 | HOXB4 | homeobox B4 | 0.241820 | -0.033594 | 5.680978 | 3.665825e-07 | 0.002750 | 5.006423 |
6 | 41308 | 200261 | LOC200261 | hypothetical protein LOC200261 | 0.464663 | -0.015904 | 5.458115 | 8.632716e-07 | 0.005551 | 4.499313 |
8 | 12053 | 2863 | GPR39 | G protein-coupled receptor 39 | 0.201463 | -0.027988 | 5.199354 | 2.302939e-06 | 0.010886 | 3.913296 |
10 | 2479 | 2353 | FOS | v-fos FBJ murine osteosarcoma viral oncogene h... | -0.652862 | 0.097279 | -5.152892 | 2.742032e-06 | 0.011221 | 3.808527 |
12 | 24570 | 4194 | MDM4 | Mdm4 p53 binding protein homolog (mouse) | -0.317245 | 0.054732 | -5.028185 | 4.368379e-06 | 0.014181 | 3.528179 |
13 | 5075 | 3398 | ID2 | inhibitor of DNA binding 2, dominant negative ... | -0.631542 | 0.093306 | -5.023820 | 4.439835e-06 | 0.014181 | 3.518391 |
14 | 5593 | 7286 | TUFT1 | tuftelin 1 | -0.324441 | 0.037927 | -5.007037 | 4.725420e-06 | 0.014181 | 3.480775 |
16 | 14058 | 11024 | LILRA1 | leukocyte immunoglobulin-like receptor, subfam... | 0.571763 | -0.028684 | 4.823671 | 9.290239e-06 | 0.024134 | 3.071645 |
17 | 18707 | 6432 | SFRS7 | splicing factor, arginine/serine-rich 7, 35kDa | -0.196261 | 0.014785 | -4.813274 | 9.650441e-06 | 0.024134 | 3.048559 |
18 | 32092 | 79608 | RIC3 | resistance to inhibitors of cholinesterase 3 h... | -0.559678 | 0.078599 | -4.782045 | 1.081643e-05 | 0.025626 | 2.979294 |
19 | 24859 | 100132363 | LOC100132363 | hypothetical protein LOC100132363 | -0.572573 | 0.114074 | -4.665798 | 1.649452e-05 | 0.037125 | 2.722550 |
20 | 1390 | 6615 | SNAI1 | snail homolog 1 (Drosophila) | -0.515691 | 0.161391 | -4.589456 | 2.171080e-05 | 0.044439 | 2.554946 |
21 | 16555 | 343071 | PRAMEF10 | PRAME family member 10 | -0.595546 | 0.072522 | -4.589357 | 2.171847e-05 | 0.044439 | 2.554731 |
Step 29. Here, the results of the DEG table are integrated into the mergeddataframe dataframe. This is followed by adjustment of the dataframe columns to remove non-relevant columns.
merged_dataframe_DEG_C3= pd.merge(mergeddataframe,Comparison_3, on='GENEID')
Step 30. Lastly, the following for loop for the key events is run to retrieve the n variable. It is comparable to the for loop of N, but adds a condition to check for significance of genes by p adjusted value being smaller than 0.05.
variable_n_dictionary_count3= {}
for index, row in merged_dataframe_DEG_C3.iterrows():
unique_KE = row['KEID']
gene_expression_value = row['adj.P.Val']
if gene_expression_value < 0.05:
if unique_KE not in variable_n_dictionary_count3:
variable_n_dictionary_count3[unique_KE] = 1
else:
variable_n_dictionary_count3[unique_KE] += 1
print("The total number of significant genes: ")
print(variable_n_dictionary_count3)
The total number of significant genes:
{'https://identifiers.org/aop.events/875': 1, 'https://identifiers.org/aop.events/1495': 1, 'https://identifiers.org/aop.events/1668 ': 1, 'https://identifiers.org/aop.events/1539': 1, 'https://identifiers.org/aop.events/188': 1, 'https://identifiers.org/aop.events/618': 1, 'https://identifiers.org/aop.events/2013': 1, 'https://identifiers.org/aop.events/1497': 2, 'https://identifiers.org/aop.events/1115': 1, 'https://identifiers.org/aop.events/1633': 4, 'https://identifiers.org/aop.events/1392': 3, 'https://identifiers.org/aop.events/386': 2, 'https://identifiers.org/aop.events/1496': 1, 'https://identifiers.org/aop.events/1493': 2, 'https://identifiers.org/aop.events/265': 2, 'https://identifiers.org/aop.events/1817': 1, 'https://identifiers.org/aop.events/1750': 2, 'https://identifiers.org/aop.events/1848': 1, 'https://identifiers.org/aop.events/1365': 1, 'https://identifiers.org/aop.events/890': 1, 'https://identifiers.org/aop.events/1457': 1, 'https://identifiers.org/aop.events/149': 4, 'https://identifiers.org/aop.events/1575': 1, 'https://identifiers.org/aop.events/249': 1, 'https://identifiers.org/aop.events/209': 1, 'https://identifiers.org/aop.events/1498': 1, 'https://identifiers.org/aop.events/1500': 1, 'https://identifiers.org/aop.events/1488': 1, 'https://identifiers.org/aop.events/52': 1, 'https://identifiers.org/aop.events/381': 1, 'https://identifiers.org/aop.events/388': 1, 'https://identifiers.org/aop.events/1262': 1, 'https://identifiers.org/aop.events/2012': 1, 'https://identifiers.org/aop.events/1271': 1, 'https://identifiers.org/aop.events/1087': 2, 'https://identifiers.org/aop.events/1538': 1, 'https://identifiers.org/aop.events/898': 1, 'https://identifiers.org/aop.events/195': 1, 'https://identifiers.org/aop.events/1090': 1, 'https://identifiers.org/aop.events/1841': 1, 'https://identifiers.org/aop.events/352': 2}
Step 31. The output of the n variable dictionary is saved as a dataframe and integrated as a separate column into a dataframe.
n_variable_dataframe3=pd.DataFrame.from_dict(variable_n_dictionary_count3,orient='index')
n_variable_dataframe3
0 | |
---|---|
https://identifiers.org/aop.events/875 | 1 |
https://identifiers.org/aop.events/1495 | 1 |
https://identifiers.org/aop.events/1668 | 1 |
https://identifiers.org/aop.events/1539 | 1 |
https://identifiers.org/aop.events/188 | 1 |
https://identifiers.org/aop.events/618 | 1 |
https://identifiers.org/aop.events/2013 | 1 |
https://identifiers.org/aop.events/1497 | 2 |
https://identifiers.org/aop.events/1115 | 1 |
https://identifiers.org/aop.events/1633 | 4 |
https://identifiers.org/aop.events/1392 | 3 |
https://identifiers.org/aop.events/386 | 2 |
https://identifiers.org/aop.events/1496 | 1 |
https://identifiers.org/aop.events/1493 | 2 |
https://identifiers.org/aop.events/265 | 2 |
https://identifiers.org/aop.events/1817 | 1 |
https://identifiers.org/aop.events/1750 | 2 |
https://identifiers.org/aop.events/1848 | 1 |
https://identifiers.org/aop.events/1365 | 1 |
https://identifiers.org/aop.events/890 | 1 |
https://identifiers.org/aop.events/1457 | 1 |
https://identifiers.org/aop.events/149 | 4 |
https://identifiers.org/aop.events/1575 | 1 |
https://identifiers.org/aop.events/249 | 1 |
https://identifiers.org/aop.events/209 | 1 |
https://identifiers.org/aop.events/1498 | 1 |
https://identifiers.org/aop.events/1500 | 1 |
https://identifiers.org/aop.events/1488 | 1 |
https://identifiers.org/aop.events/52 | 1 |
https://identifiers.org/aop.events/381 | 1 |
https://identifiers.org/aop.events/388 | 1 |
https://identifiers.org/aop.events/1262 | 1 |
https://identifiers.org/aop.events/2012 | 1 |
https://identifiers.org/aop.events/1271 | 1 |
https://identifiers.org/aop.events/1087 | 2 |
https://identifiers.org/aop.events/1538 | 1 |
https://identifiers.org/aop.events/898 | 1 |
https://identifiers.org/aop.events/195 | 1 |
https://identifiers.org/aop.events/1090 | 1 |
https://identifiers.org/aop.events/1841 | 1 |
https://identifiers.org/aop.events/352 | 2 |
n_variable_dataframe3_reset = n_variable_dataframe3.reset_index()
n_variable_dataframe3_reset.columns = ['KEID', 'n']
n_variable_dataframe3_reset
KEID | n | |
---|---|---|
0 | https://identifiers.org/aop.events/875 | 1 |
1 | https://identifiers.org/aop.events/1495 | 1 |
2 | https://identifiers.org/aop.events/1668 | 1 |
3 | https://identifiers.org/aop.events/1539 | 1 |
4 | https://identifiers.org/aop.events/188 | 1 |
5 | https://identifiers.org/aop.events/618 | 1 |
6 | https://identifiers.org/aop.events/2013 | 1 |
7 | https://identifiers.org/aop.events/1497 | 2 |
8 | https://identifiers.org/aop.events/1115 | 1 |
9 | https://identifiers.org/aop.events/1633 | 4 |
10 | https://identifiers.org/aop.events/1392 | 3 |
11 | https://identifiers.org/aop.events/386 | 2 |
12 | https://identifiers.org/aop.events/1496 | 1 |
13 | https://identifiers.org/aop.events/1493 | 2 |
14 | https://identifiers.org/aop.events/265 | 2 |
15 | https://identifiers.org/aop.events/1817 | 1 |
16 | https://identifiers.org/aop.events/1750 | 2 |
17 | https://identifiers.org/aop.events/1848 | 1 |
18 | https://identifiers.org/aop.events/1365 | 1 |
19 | https://identifiers.org/aop.events/890 | 1 |
20 | https://identifiers.org/aop.events/1457 | 1 |
21 | https://identifiers.org/aop.events/149 | 4 |
22 | https://identifiers.org/aop.events/1575 | 1 |
23 | https://identifiers.org/aop.events/249 | 1 |
24 | https://identifiers.org/aop.events/209 | 1 |
25 | https://identifiers.org/aop.events/1498 | 1 |
26 | https://identifiers.org/aop.events/1500 | 1 |
27 | https://identifiers.org/aop.events/1488 | 1 |
28 | https://identifiers.org/aop.events/52 | 1 |
29 | https://identifiers.org/aop.events/381 | 1 |
30 | https://identifiers.org/aop.events/388 | 1 |
31 | https://identifiers.org/aop.events/1262 | 1 |
32 | https://identifiers.org/aop.events/2012 | 1 |
33 | https://identifiers.org/aop.events/1271 | 1 |
34 | https://identifiers.org/aop.events/1087 | 2 |
35 | https://identifiers.org/aop.events/1538 | 1 |
36 | https://identifiers.org/aop.events/898 | 1 |
37 | https://identifiers.org/aop.events/195 | 1 |
38 | https://identifiers.org/aop.events/1090 | 1 |
39 | https://identifiers.org/aop.events/1841 | 1 |
40 | https://identifiers.org/aop.events/352 | 2 |
merged_dataframe4= pd.merge(mergeddataframe, n_variable_dataframe3_reset, on='KEID')
Section 7.2. Calculation of variable B and variable b.
In this section, variable B and variable b are calculated.
Step 32. Variable B is calculated by taking the length of the dataframe which includes all genes in 1 DEG table.
B=len(The_Comparison3_DEG.index)
B
19751
Step 33. Variable b is calculated by taking the length of the dataframe which includes all genes in 1 DEG table with the condition for significance.
The_Comparison3_DEG_filtered=The_Comparison3_DEG[The_Comparison3_DEG['adj.P.Val'] < 0.05]
b=len(The_Comparison3_DEG_filtered)
b
16
Section 7.3. Calculation of enrichment score and hypergeometric p-value
In this section, the enrichment score and hypergeometric p-value will be calculated. This requires the four variables of the enrichment score per KE for which the formula will be applied to and stored in an additional dataframe.
Step 34. The final dataframe will be created that contains the KEID and the four variables: variable N, variable n, variable B and variable b.
Final_dataframe_ES= merged_dataframe4.loc[:, ['KEID','N','n']]
Final_dataframe_ES['B']=pd.Series([19751 for x in range(len(Final_dataframe_ES.index))])
Final_dataframe_ES['b']=pd.Series([16 for x in range(len(Final_dataframe_ES.index))])
Final_Dataframe_ES=Final_dataframe_ES.drop_duplicates(subset=['KEID'],keep='first')
Final_Dataframe_ES.reset_index(drop=True,inplace=True)
Copy_Final_DataFrame_ES=Final_Dataframe_ES.copy()
Step 35. The following for loop will be used to calculate the enrichment score for individual key events and the results will be saved as a separate column into the dataframe.
def calculate_Enrichment_Score(row):
return f"{(row['n']/row['N'])/(row['b']/row['B'])}"
Copy_Final_DataFrame_ES.loc[:,'Enrichmentscore']= Copy_Final_DataFrame_ES.apply(calculate_Enrichment_Score,axis=1)
Copy_Final_DataFrame_ES
KEID | N | n | B | b | Enrichmentscore | |
---|---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/875 | 169 | 1 | 19751 | 16 | 7.304363905325443 |
1 | https://identifiers.org/aop.events/1495 | 253 | 1 | 19751 | 16 | 4.879199604743082 |
2 | https://identifiers.org/aop.events/1668 | 156 | 1 | 19751 | 16 | 7.913060897435897 |
3 | https://identifiers.org/aop.events/1539 | 170 | 1 | 19751 | 16 | 7.261397058823529 |
4 | https://identifiers.org/aop.events/188 | 17 | 1 | 19751 | 16 | 72.61397058823529 |
5 | https://identifiers.org/aop.events/618 | 240 | 1 | 19751 | 16 | 5.143489583333333 |
6 | https://identifiers.org/aop.events/2013 | 100 | 1 | 19751 | 16 | 12.344375 |
7 | https://identifiers.org/aop.events/1497 | 528 | 2 | 19751 | 16 | 4.675899621212121 |
8 | https://identifiers.org/aop.events/1115 | 34 | 1 | 19751 | 16 | 36.306985294117645 |
9 | https://identifiers.org/aop.events/1633 | 1056 | 4 | 19751 | 16 | 4.675899621212121 |
10 | https://identifiers.org/aop.events/1392 | 102 | 3 | 19751 | 16 | 36.306985294117645 |
11 | https://identifiers.org/aop.events/386 | 372 | 2 | 19751 | 16 | 6.636760752688172 |
12 | https://identifiers.org/aop.events/1496 | 406 | 1 | 19751 | 16 | 3.04048645320197 |
13 | https://identifiers.org/aop.events/1493 | 812 | 2 | 19751 | 16 | 3.04048645320197 |
14 | https://identifiers.org/aop.events/265 | 268 | 2 | 19751 | 16 | 9.212220149253731 |
15 | https://identifiers.org/aop.events/1817 | 328 | 1 | 19751 | 16 | 3.7635289634146343 |
16 | https://identifiers.org/aop.events/1750 | 528 | 2 | 19751 | 16 | 4.675899621212121 |
17 | https://identifiers.org/aop.events/1848 | 195 | 1 | 19751 | 16 | 6.330448717948718 |
18 | https://identifiers.org/aop.events/1365 | 328 | 1 | 19751 | 16 | 3.7635289634146343 |
19 | https://identifiers.org/aop.events/890 | 34 | 1 | 19751 | 16 | 36.306985294117645 |
20 | https://identifiers.org/aop.events/1457 | 19 | 1 | 19751 | 16 | 64.9703947368421 |
21 | https://identifiers.org/aop.events/149 | 1056 | 4 | 19751 | 16 | 4.675899621212121 |
22 | https://identifiers.org/aop.events/1575 | 328 | 1 | 19751 | 16 | 3.7635289634146343 |
23 | https://identifiers.org/aop.events/249 | 34 | 1 | 19751 | 16 | 36.306985294117645 |
24 | https://identifiers.org/aop.events/209 | 617 | 1 | 19751 | 16 | 2.00070907617504 |
25 | https://identifiers.org/aop.events/1498 | 224 | 1 | 19751 | 16 | 5.510881696428571 |
26 | https://identifiers.org/aop.events/1500 | 260 | 1 | 19751 | 16 | 4.747836538461539 |
27 | https://identifiers.org/aop.events/1488 | 184 | 1 | 19751 | 16 | 6.708899456521738 |
28 | https://identifiers.org/aop.events/52 | 219 | 1 | 19751 | 16 | 5.6367009132420085 |
29 | https://identifiers.org/aop.events/381 | 199 | 1 | 19751 | 16 | 6.20320351758794 |
30 | https://identifiers.org/aop.events/388 | 169 | 1 | 19751 | 16 | 7.304363905325443 |
31 | https://identifiers.org/aop.events/1262 | 328 | 1 | 19751 | 16 | 3.7635289634146343 |
32 | https://identifiers.org/aop.events/2012 | 260 | 1 | 19751 | 16 | 4.747836538461539 |
33 | https://identifiers.org/aop.events/1271 | 58 | 1 | 19751 | 16 | 21.28340517241379 |
34 | https://identifiers.org/aop.events/1087 | 528 | 2 | 19751 | 16 | 4.675899621212121 |
35 | https://identifiers.org/aop.events/1538 | 34 | 1 | 19751 | 16 | 36.306985294117645 |
36 | https://identifiers.org/aop.events/898 | 328 | 1 | 19751 | 16 | 3.7635289634146343 |
37 | https://identifiers.org/aop.events/195 | 184 | 1 | 19751 | 16 | 6.708899456521738 |
38 | https://identifiers.org/aop.events/1090 | 459 | 1 | 19751 | 16 | 2.689406318082789 |
39 | https://identifiers.org/aop.events/1841 | 17 | 1 | 19751 | 16 | 72.61397058823529 |
40 | https://identifiers.org/aop.events/352 | 398 | 2 | 19751 | 16 | 6.20320351758794 |
Step 36. The following for loop will be used to calculate the hypergeometric p-value for individual Key Events and save the result as a separate column into the dataframe. This requires some in between steps for manipulation of the dataframe.
p_value_dataframe3=[]
for index, row in Copy_Final_DataFrame_ES.iterrows():
M = row['B']
n = row['b']
N = row['N']
k = row['n']
hpd = ss.hypergeom(M, n, N)
p = hpd.pmf(k)
p_value_dataframe3.append(p)
Hypergeometricpvalue_dataframe3=pd.DataFrame(p_value_dataframe3)
Hypergeometricpvalue_dataframe3.columns= ['Hypergeometric p-value']
Hypergeometricpvalue_dataframe3
Hypergeometric p-value | |
---|---|
0 | 0.120433 |
1 | 0.169031 |
2 | 0.112282 |
3 | 0.121053 |
4 | 0.013605 |
5 | 0.161957 |
6 | 0.075125 |
7 | 0.058652 |
8 | 0.026860 |
9 | 0.007667 |
10 | 0.000070 |
11 | 0.032577 |
12 | 0.241009 |
13 | 0.112689 |
14 | 0.018205 |
15 | 0.206825 |
16 | 0.058652 |
17 | 0.136219 |
18 | 0.206825 |
19 | 0.026860 |
20 | 0.015182 |
21 | 0.007667 |
22 | 0.206825 |
23 | 0.026860 |
24 | 0.310686 |
25 | 0.153031 |
26 | 0.172774 |
27 | 0.129624 |
28 | 0.150191 |
29 | 0.138587 |
30 | 0.120433 |
31 | 0.206825 |
32 | 0.172774 |
33 | 0.044991 |
34 | 0.058652 |
35 | 0.026860 |
36 | 0.206825 |
37 | 0.129624 |
38 | 0.261482 |
39 | 0.013605 |
40 | 0.036602 |
merged_finaltable_AgNp_24h=pd.concat([Copy_Final_DataFrame_ES,Hypergeometricpvalue_dataframe3],axis=1)
Section 7.4. Filtering the results for significant KEs
In this section, the results will be filtered to only include significant KEs. Significant KEs have an enrichment score above 1 and a hypergeometric p-value below 0.05.
Step 37. Lastly, we filter the results to showcase the significant KEs for the comparison: Bisphenol A 1uM.
filteredversion_C3= merged_finaltable_AgNp_24h[(merged_finaltable_AgNp_24h['Enrichmentscore']>str(1))& (merged_finaltable_AgNp_24h['Hypergeometric p-value'] < 0.05)]
filteredversion_C3
KEID | N | n | B | b | Enrichmentscore | Hypergeometric p-value | |
---|---|---|---|---|---|---|---|
4 | https://identifiers.org/aop.events/188 | 17 | 1 | 19751 | 16 | 72.61397058823529 | 0.013605 |
8 | https://identifiers.org/aop.events/1115 | 34 | 1 | 19751 | 16 | 36.306985294117645 | 0.026860 |
9 | https://identifiers.org/aop.events/1633 | 1056 | 4 | 19751 | 16 | 4.675899621212121 | 0.007667 |
10 | https://identifiers.org/aop.events/1392 | 102 | 3 | 19751 | 16 | 36.306985294117645 | 0.000070 |
11 | https://identifiers.org/aop.events/386 | 372 | 2 | 19751 | 16 | 6.636760752688172 | 0.032577 |
14 | https://identifiers.org/aop.events/265 | 268 | 2 | 19751 | 16 | 9.212220149253731 | 0.018205 |
19 | https://identifiers.org/aop.events/890 | 34 | 1 | 19751 | 16 | 36.306985294117645 | 0.026860 |
20 | https://identifiers.org/aop.events/1457 | 19 | 1 | 19751 | 16 | 64.9703947368421 | 0.015182 |
21 | https://identifiers.org/aop.events/149 | 1056 | 4 | 19751 | 16 | 4.675899621212121 | 0.007667 |
23 | https://identifiers.org/aop.events/249 | 34 | 1 | 19751 | 16 | 36.306985294117645 | 0.026860 |
33 | https://identifiers.org/aop.events/1271 | 58 | 1 | 19751 | 16 | 21.28340517241379 | 0.044991 |
35 | https://identifiers.org/aop.events/1538 | 34 | 1 | 19751 | 16 | 36.306985294117645 | 0.026860 |
39 | https://identifiers.org/aop.events/1841 | 17 | 1 | 19751 | 16 | 72.61397058823529 | 0.013605 |
40 | https://identifiers.org/aop.events/352 | 398 | 2 | 19751 | 16 | 6.20320351758794 | 0.036602 |
Section 7.5. Calculation of percent gene overlap to ORA
Section 7.5.1 Creation of the significant KEs table
In this section, you merge the dataframes to retrieve the genes connected to only the significant KEs.
Step 38. The significant KE table is created using the significan KEs from the previous merggeddataframe_final.
significantKEID_genetable3=mergeddataframe_final2[(mergeddataframe_final2['KEID'] == 'https://identifiers.org/aop.events/188')| (mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1115') | (mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1633')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1392')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/386')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/265')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/890')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/1457')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/149')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/249')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/1271')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/1538')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/1841')| (mergeddataframe_final2['KEID']=='https://identifiers.org/aop.events/352')]
significantKEIDgenetable3=significantKEID_genetable3.drop(columns={'WPtitle','ID'})
significantKEIDgenetable3
KEID | gene | GENEID | |
---|---|---|---|
3555 | https://identifiers.org/aop.events/188 | MTOR | 2475 |
3556 | https://identifiers.org/aop.events/188 | CHUK | 1147 |
3557 | https://identifiers.org/aop.events/188 | JUN | 3725 |
3558 | https://identifiers.org/aop.events/188 | JUN | 609429 |
3559 | https://identifiers.org/aop.events/188 | FOS | 2353 |
... | ... | ... | ... |
20878 | https://identifiers.org/aop.events/352 | ADCY1 | 107 |
20879 | https://identifiers.org/aop.events/352 | GRIN1 | 2902 |
20880 | https://identifiers.org/aop.events/352 | GRB2 | 2885 |
20881 | https://identifiers.org/aop.events/352 | BRAF | 673 |
20882 | https://identifiers.org/aop.events/352 | HOMER1 | 9456 |
3499 rows × 3 columns
Section 7.5.2 Significant ORA pathway table plus splitting
In this section, the significant ORA pathway table is created.
Step 39. The significant ORA pathway table is created using the significant enriched patwhays identified from the ORA analysis. This requires data manipulation to restructure the table in a way that the individual genes for the enriched pathways are placed on individual rows.
datafile_ORA3 = pd.read_csv("C:/Users/shaki/Downloads/GSE44729_ORApathwaytable/Comparison 3-CP timepoint 1.txt", sep='\t')
datafileORA3=pd.DataFrame(datafile_ORA3)
filtereddatafileORA_3=datafileORA3[datafileORA3['Adjusted P-value'] < 0.05]
Gene_set | Term | P-value | Adjusted P-value | Old P-value | Old adjusted P-value | Odds Ratio | Combined Score | Genes | |
---|---|---|---|---|---|---|---|---|---|
0 | WikiPathways_2024_Human | Hepatitis B Infection WP4666 | 0.001378 | 0.040029 | 0 | 0 | 47.00719 | 309.6488 | EGR3;FOS |
1 | WikiPathways_2024_Human | Epithelial To Mesenchymal Transition In Colore... | 0.001704 | 0.040029 | 0 | 0 | 42.12043 | 268.5097 | ID2;SNAI1 |
2 | WikiPathways_2024_Human | miR 517 Relationship With ARCN1 And USP1 WP3596 | 0.002024 | 0.040029 | 0 | 0 | 704.89290 | 4372.2430 | ID2 |
3 | WikiPathways_2024_Human | Circadian Rhythm Genes WP3594 | 0.002456 | 0.040029 | 0 | 0 | 34.85561 | 209.4550 | EGR3;ID2 |
4 | WikiPathways_2024_Human | Neuroinflammation WP4919 | 0.004448 | 0.040029 | 0 | 0 | 281.87140 | 1526.4210 | FOS |
5 | WikiPathways_2024_Human | Development Of Pulmonary Dendritic Cells And M... | 0.005255 | 0.040029 | 0 | 0 | 234.86900 | 1232.7350 | ID2 |
6 | WikiPathways_2024_Human | Serotonin And Anxiety Related Events WP3944 | 0.005255 | 0.040029 | 0 | 0 | 234.86900 | 1232.7350 | FOS |
7 | WikiPathways_2024_Human | MAPK Pathway In Congenital Thyroid Cancer WP4928 | 0.006061 | 0.040029 | 0 | 0 | 201.29590 | 1027.7890 | FOS |
8 | WikiPathways_2024_Human | Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 | 0.006464 | 0.040029 | 0 | 0 | 187.86670 | 947.1295 | FOS |
9 | WikiPathways_2024_Human | ID Signaling WP53 | 0.006464 | 0.040029 | 0 | 0 | 187.86670 | 947.1295 | ID2 |
10 | WikiPathways_2024_Human | Galanin Receptor Pathway WP4970 | 0.006464 | 0.040029 | 0 | 0 | 187.86670 | 947.1295 | FOS |
11 | WikiPathways_2024_Human | TGF Beta In Thyroid Cells For Epithelial Mesen... | 0.006867 | 0.040029 | 0 | 0 | 176.11610 | 877.2431 | SNAI1 |
12 | WikiPathways_2024_Human | Serotonin And Anxiety WP3947 | 0.006867 | 0.040029 | 0 | 0 | 176.11610 | 877.2431 | FOS |
13 | WikiPathways_2024_Human | Cell Differentiation Expanded Index WP2023 | 0.007672 | 0.040029 | 0 | 0 | 156.53170 | 762.3376 | ID2 |
14 | WikiPathways_2024_Human | Estrogen Signaling WP712 | 0.008879 | 0.040029 | 0 | 0 | 134.14970 | 633.7372 | FOS |
15 | WikiPathways_2024_Human | Photodynamic Therapy Induced NFE2L2 NRF2 Survi... | 0.009281 | 0.040029 | 0 | 0 | 128.04550 | 599.2311 | FOS |
16 | WikiPathways_2024_Human | Physiological And Pathological Hypertrophy Of ... | 0.009682 | 0.040029 | 0 | 0 | 122.47200 | 567.9579 | FOS |
17 | WikiPathways_2024_Human | FGFR3 Signal Chondrocyte Proliferation Termina... | 0.010486 | 0.040029 | 0 | 0 | 112.66290 | 513.4903 | SNAI1 |
18 | WikiPathways_2024_Human | PDGFR Beta Pathway WP3972 | 0.011689 | 0.040029 | 0 | 0 | 100.57650 | 447.4742 | FOS |
19 | WikiPathways_2024_Human | Host Pathogen Interaction Of Human CoV Interfe... | 0.012491 | 0.040029 | 0 | 0 | 93.86190 | 411.3737 | FOS |
20 | WikiPathways_2024_Human | Hair Follicle Development Organogenesis Part 2... | 0.012892 | 0.040029 | 0 | 0 | 90.82949 | 395.2157 | SNAI1 |
21 | WikiPathways_2024_Human | Development And Heterogeneity Of The ILC Famil... | 0.012892 | 0.040029 | 0 | 0 | 90.82949 | 395.2157 | ID2 |
22 | WikiPathways_2024_Human | Oxidative Stress Response WP408 | 0.013292 | 0.040029 | 0 | 0 | 87.98661 | 380.1539 | FOS |
23 | WikiPathways_2024_Human | Selenium Metabolism And Selenoproteins WP28 | 0.013292 | 0.040029 | 0 | 0 | 87.98661 | 380.1539 | FOS |
24 | WikiPathways_2024_Human | Hepatocyte Growth Factor Receptor Signaling WP313 | 0.013692 | 0.040029 | 0 | 0 | 85.31602 | 366.0835 | FOS |
25 | WikiPathways_2024_Human | Host Pathogen Interaction Of Human Coronavirus... | 0.014493 | 0.040029 | 0 | 0 | 80.43265 | 340.5605 | FOS |
26 | WikiPathways_2024_Human | Serotonin HTR1 Group And FOS Pathway WP722 | 0.014893 | 0.040029 | 0 | 0 | 78.19444 | 328.9551 | FOS |
27 | WikiPathways_2024_Human | Sleep Regulation WP3591 | 0.014893 | 0.040029 | 0 | 0 | 78.19444 | 328.9551 | FOS |
28 | WikiPathways_2024_Human | Neural Crest Cell Migration During Development... | 0.015292 | 0.040029 | 0 | 0 | 76.07722 | 318.0328 | FOS |
29 | WikiPathways_2024_Human | PDGF Pathway WP2526 | 0.015692 | 0.040029 | 0 | 0 | 74.07143 | 307.7368 | FOS |
30 | WikiPathways_2024_Human | Neural Crest Cell Migration In Cancer WP4565 | 0.016491 | 0.040029 | 0 | 0 | 70.36071 | 288.8265 | FOS |
31 | WikiPathways_2024_Human | Osteoarthritic Chondrocyte Hypertrophy WP5373 | 0.018486 | 0.040029 | 0 | 0 | 62.52698 | 249.5299 | FOS |
32 | WikiPathways_2024_Human | Interleukin 1 IL 1 Structural Pathway WP2637 | 0.018486 | 0.040029 | 0 | 0 | 62.52698 | 249.5299 | FOS |
33 | WikiPathways_2024_Human | RANKL RANK Signaling WP2018 | 0.018884 | 0.040029 | 0 | 0 | 61.16460 | 242.7883 | FOS |
34 | WikiPathways_2024_Human | IL3 Signaling WP286 | 0.019283 | 0.040029 | 0 | 0 | 59.86018 | 236.3609 | FOS |
35 | WikiPathways_2024_Human | Senescence Associated Secretory Phenotype SASP... | 0.019681 | 0.040029 | 0 | 0 | 58.61012 | 230.2268 | FOS |
36 | WikiPathways_2024_Human | Photodynamic Therapy Induced AP 1 Survival Sig... | 0.020079 | 0.040029 | 0 | 0 | 57.41108 | 224.3671 | FOS |
37 | WikiPathways_2024_Human | IL4 Signaling WP395 | 0.020079 | 0.040029 | 0 | 0 | 57.41108 | 224.3671 | FOS |
38 | WikiPathways_2024_Human | NRP1 Triggered Signaling In Pancreatic Cancer ... | 0.020875 | 0.040029 | 0 | 0 | 55.15406 | 213.4029 | SNAI1 |
39 | WikiPathways_2024_Human | Neurogenesis Regulation In The Olfactory Epith... | 0.021670 | 0.040029 | 0 | 0 | 53.06739 | 203.3451 | ID2 |
40 | WikiPathways_2024_Human | TGF Beta Receptor Signaling WP560 | 0.021670 | 0.040029 | 0 | 0 | 53.06739 | 203.3451 | FOS |
41 | WikiPathways_2024_Human | Hematopoietic SC Differentiation WP2849 | 0.021670 | 0.040029 | 0 | 0 | 53.06739 | 203.3451 | FOS |
42 | WikiPathways_2024_Human | Oncostatin M Signaling WP2374 | 0.022067 | 0.040029 | 0 | 0 | 52.08201 | 198.6229 | FOS |
43 | WikiPathways_2024_Human | TGF Beta Receptor Signaling In Skeletal Dyspla... | 0.023259 | 0.041231 | 0 | 0 | 49.33333 | 185.5464 | FOS |
44 | WikiPathways_2024_Human | T Cell Antigen Receptor TCR Pathway During Sta... | 0.024449 | 0.042378 | 0 | 0 | 46.85952 | 173.9040 | FOS |
45 | WikiPathways_2024_Human | Endometrial Cancer WP4155 | 0.025241 | 0.042801 | 0 | 0 | 45.34332 | 166.8303 | FOS |
46 | WikiPathways_2024_Human | Melanoma WP4685 | 0.026825 | 0.043591 | 0 | 0 | 42.58658 | 154.0961 | FOS |
47 | WikiPathways_2024_Human | Th17 Cell Differentiation Pathway WP5130 | 0.026825 | 0.043591 | 0 | 0 | 42.58658 | 154.0961 | FOS |
48 | WikiPathways_2024_Human | Chromosomal And Microsatellite Instability In ... | 0.029196 | 0.045257 | 0 | 0 | 39.02579 | 137.9060 | FOS |
49 | WikiPathways_2024_Human | Prolactin Signaling WP2037 | 0.029196 | 0.045257 | 0 | 0 | 39.02579 | 137.9060 | FOS |
50 | WikiPathways_2024_Human | T Cell Receptor Signaling WP69 | 0.029591 | 0.045257 | 0 | 0 | 38.48924 | 135.4931 | FOS |
51 | WikiPathways_2024_Human | T Cell Activation SARS CoV 2 WP5098 | 0.033137 | 0.047798 | 0 | 0 | 34.24913 | 116.6903 | FOS |
52 | WikiPathways_2024_Human | Polycystic Kidney Disease Pathway WP2571 | 0.033137 | 0.047798 | 0 | 0 | 34.24913 | 116.6903 | FOS |
53 | WikiPathways_2024_Human | Hair Follicle Development Cytodifferentiation ... | 0.033530 | 0.047798 | 0 | 0 | 33.83477 | 114.8793 | FOS |
54 | WikiPathways_2024_Human | Apoptosis Modulation And Signaling WP1772 | 0.034317 | 0.047798 | 0 | 0 | 33.03529 | 111.3991 | FOS |
55 | WikiPathways_2024_Human | Toll Like Receptor Signaling WP75 | 0.034317 | 0.047798 | 0 | 0 | 33.03529 | 111.3991 | FOS |
56 | WikiPathways_2024_Human | Corticotropin Releasing Hormone Signaling WP2355 | 0.035495 | 0.048572 | 0 | 0 | 31.90422 | 106.5080 | FOS |
dropped_datafileORA_df3=filtereddatafileORA_3.drop(['Adjusted P-value','Odds Ratio','Old P-value','Gene_set','P-value','Old adjusted P-value','Combined Score'],axis=1)
droppeddatafileORAdf3=dropped_datafileORA_df3.copy()
droppeddatafileORAdf3['Genes']= droppeddatafileORAdf3['Genes'].replace({';':','},regex=True)
df3_ORApathwaytable=droppeddatafileORAdf3.copy()
df3_ORApathwaytable['Genes'] = df3_ORApathwaytable['Genes'].astype(str)
df3_ORApathwaytable['Genes'] = df3_ORApathwaytable['Genes'].str.split(',')
exploded_df3_ORApathwaytable = df3_ORApathwaytable.explode('Genes', ignore_index=True)
Section 7.5.3 For loop to get overlapping genes
In this section, the number of overlapping genes between the significant enrichment score-based Key Events and enriched pathways from ORA are calculated.
Step 40. Next, two sets are created by converting the significant KE table and ORA pathway table into dictionaries where the values of the genes are grouped together per key. This is followed by running a for loop to calculate the number of overlapping genes along with the symbols.
ORA_gene_sets3 = exploded_df3_ORApathwaytable.groupby('Term')['Genes'].apply(set).to_dict()
SignificantKE_gene_sets3 = significantKEIDgenetable3.groupby('KEID')['gene'].apply(set).to_dict()
overlapping_genes_betweenORA_and_significantKEs3 = {}
for term, ORA_genes in ORA_gene_sets3.items():
for KEID, KEID_genes in SignificantKE_gene_sets3.items():
overlap = ORA_genes.intersection(KEID_genes)
print(f"{term} x {KEID}: {len(overlap)} overlaps")
overlapping_genes_betweenORA_and_significantKEs3[(term, KEID)] = {
'overlapping genes': overlap,
'number of genes that overlap': len(overlap)
}
if overlapping_genes_betweenORA_and_significantKEs3:
print("\ntitle of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:")
for (term, KEID), result in overlapping_genes_betweenORA_and_significantKEs3.items():
print(f"Term: {term}, KEID: {KEID}, Title of overlapping gene(s): {result['overlapping genes']}, number: {result['number of genes that overlap']}")
else:
print("No overlapping genes")
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1115: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1271: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1392: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1457: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/149: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1538: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1633: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1841: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/188: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/249: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/265: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/352: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/386: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/890: 1 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1115: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1271: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1392: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1457: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/149: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1538: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1633: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/1841: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/188: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/249: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/265: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/352: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/386: 0 overlaps
Cell Differentiation Expanded Index WP2023 x https://identifiers.org/aop.events/890: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1115: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1271: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1392: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1457: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/149: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1538: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1633: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1841: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/188: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/249: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/265: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/352: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/386: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/890: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1115: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1271: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1392: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1457: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/149: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1538: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1633: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1841: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/188: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/249: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/265: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/352: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/386: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/890: 0 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1115: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1271: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1392: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1457: 0 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/149: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1538: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1633: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/1841: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/188: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/249: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/265: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/352: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/386: 1 overlaps
Corticotropin Releasing Hormone Signaling WP2355 x https://identifiers.org/aop.events/890: 1 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1115: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1271: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1392: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1457: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/149: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1538: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1633: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/1841: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/188: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/249: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/265: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/352: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/386: 0 overlaps
Development And Heterogeneity Of The ILC Family WP3893 x https://identifiers.org/aop.events/890: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1115: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1271: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1392: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1457: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/149: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1538: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1633: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1841: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/188: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/249: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/265: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/352: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/386: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/890: 0 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1115: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1271: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1392: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1457: 0 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/149: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1538: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1633: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/1841: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/188: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/249: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/265: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/352: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/386: 1 overlaps
Endometrial Cancer WP4155 x https://identifiers.org/aop.events/890: 1 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1115: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1271: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1392: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1457: 1 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/149: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1538: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1633: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/1841: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/188: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/249: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/265: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/352: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/386: 0 overlaps
Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239 x https://identifiers.org/aop.events/890: 0 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1115: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1271: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1392: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1457: 0 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/149: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1538: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1633: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/1841: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/188: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/249: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/265: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/352: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/386: 1 overlaps
Estrogen Signaling WP712 x https://identifiers.org/aop.events/890: 1 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1115: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1271: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1392: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1457: 1 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/149: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1538: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1633: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/1841: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/188: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/249: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/265: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/352: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/386: 0 overlaps
FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767 x https://identifiers.org/aop.events/890: 0 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1115: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1271: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1392: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1457: 0 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/149: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1538: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1633: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/1841: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/188: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/249: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/265: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/352: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/386: 1 overlaps
Galanin Receptor Pathway WP4970 x https://identifiers.org/aop.events/890: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1115: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1271: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1392: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1457: 0 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/149: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1538: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1633: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/1841: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/188: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/249: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/265: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/352: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/386: 1 overlaps
Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840 x https://identifiers.org/aop.events/890: 1 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1115: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1271: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1392: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1457: 1 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/149: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1538: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1633: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/1841: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/188: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/249: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/265: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/352: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/386: 0 overlaps
Hair Follicle Development Organogenesis Part 2 Of 3 WP2839 x https://identifiers.org/aop.events/890: 0 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1115: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1271: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1392: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1457: 0 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/149: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1538: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1633: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/1841: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/188: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/249: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/265: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/352: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/386: 1 overlaps
Hematopoietic SC Differentiation WP2849 x https://identifiers.org/aop.events/890: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1115: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1271: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1392: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1457: 0 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/149: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1538: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1633: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/1841: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/188: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/249: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/265: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/352: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/386: 1 overlaps
Hepatitis B Infection WP4666 x https://identifiers.org/aop.events/890: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1115: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1271: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1392: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1457: 0 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/149: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1538: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1633: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/1841: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/188: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/249: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/265: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/352: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/386: 1 overlaps
Hepatocyte Growth Factor Receptor Signaling WP313 x https://identifiers.org/aop.events/890: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1115: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1271: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1392: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1457: 0 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/149: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1538: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1633: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/1841: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/188: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/249: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/265: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/352: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/386: 1 overlaps
Host Pathogen Interaction Of Human CoV Interferon Induction WP4880 x https://identifiers.org/aop.events/890: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1115: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1271: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1392: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1457: 0 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/149: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1538: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1633: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/1841: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/188: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/249: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/265: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/352: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/386: 1 overlaps
Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877 x https://identifiers.org/aop.events/890: 1 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1115: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1271: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1392: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1457: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/149: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1538: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1633: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/1841: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/188: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/249: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/265: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/352: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/386: 0 overlaps
ID Signaling WP53 x https://identifiers.org/aop.events/890: 0 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1115: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1271: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1392: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1457: 0 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/149: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1538: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1633: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/1841: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/188: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/249: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/265: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/352: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/386: 1 overlaps
IL3 Signaling WP286 x https://identifiers.org/aop.events/890: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1115: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1271: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1392: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1457: 0 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/149: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1538: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1633: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/1841: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/188: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/249: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/265: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/352: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/386: 1 overlaps
IL4 Signaling WP395 x https://identifiers.org/aop.events/890: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1115: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1271: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1392: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1457: 0 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/149: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1538: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1633: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/1841: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/188: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/249: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/265: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/352: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/386: 1 overlaps
Interleukin 1 IL 1 Structural Pathway WP2637 x https://identifiers.org/aop.events/890: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1115: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1271: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1392: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1457: 0 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/149: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1538: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1633: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/1841: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/188: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/249: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/265: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/352: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/386: 1 overlaps
MAPK Pathway In Congenital Thyroid Cancer WP4928 x https://identifiers.org/aop.events/890: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1115: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1271: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1392: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1457: 0 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/149: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1538: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1633: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/1841: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/188: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/249: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/265: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/352: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/386: 1 overlaps
Melanoma WP4685 x https://identifiers.org/aop.events/890: 1 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1115: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1271: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1392: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1457: 1 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/149: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1538: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1633: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/1841: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/188: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/249: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/265: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/352: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/386: 0 overlaps
NRP1 Triggered Signaling In Pancreatic Cancer WP5144 x https://identifiers.org/aop.events/890: 0 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1115: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1271: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1392: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1457: 0 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/149: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1538: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1633: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/1841: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/188: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/249: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/265: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/352: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/386: 1 overlaps
Neural Crest Cell Migration During Development WP4564 x https://identifiers.org/aop.events/890: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1115: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1271: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1392: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1457: 0 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/149: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1538: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1633: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/1841: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/188: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/249: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/265: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/352: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/386: 1 overlaps
Neural Crest Cell Migration In Cancer WP4565 x https://identifiers.org/aop.events/890: 1 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1115: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1271: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1392: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1457: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/149: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1538: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1633: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/1841: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/188: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/249: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/265: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/352: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/386: 0 overlaps
Neurogenesis Regulation In The Olfactory Epithelium WP5265 x https://identifiers.org/aop.events/890: 0 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1115: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1271: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1392: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1457: 0 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/149: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1538: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1633: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/1841: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/188: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/249: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/265: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/352: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/386: 1 overlaps
Neuroinflammation WP4919 x https://identifiers.org/aop.events/890: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1115: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1271: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1392: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1457: 0 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/149: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1538: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1633: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/1841: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/188: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/249: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/265: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/352: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/386: 1 overlaps
Oncostatin M Signaling WP2374 x https://identifiers.org/aop.events/890: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1115: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1271: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1392: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1457: 0 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/149: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1538: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1633: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/1841: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/188: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/249: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/265: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/352: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/386: 1 overlaps
Osteoarthritic Chondrocyte Hypertrophy WP5373 x https://identifiers.org/aop.events/890: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1115: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1271: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1392: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1457: 0 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/149: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1538: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1633: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/1841: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/188: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/249: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/265: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/352: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/386: 1 overlaps
Oxidative Stress Response WP408 x https://identifiers.org/aop.events/890: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1115: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1271: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1392: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1457: 0 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/149: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1538: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1633: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/1841: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/188: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/249: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/265: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/352: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/386: 1 overlaps
PDGF Pathway WP2526 x https://identifiers.org/aop.events/890: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1115: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1271: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1392: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1457: 0 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/149: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1538: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1633: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/1841: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/188: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/249: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/265: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/352: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/386: 1 overlaps
PDGFR Beta Pathway WP3972 x https://identifiers.org/aop.events/890: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1115: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1271: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1392: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1457: 0 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/149: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1538: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1633: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/1841: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/188: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/249: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/265: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/352: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/386: 1 overlaps
Photodynamic Therapy Induced AP 1 Survival Signaling WP3611 x https://identifiers.org/aop.events/890: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1115: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1271: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1392: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1457: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/149: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1538: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1633: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1841: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/188: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/249: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/265: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/352: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/386: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/890: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1115: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1271: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1392: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1457: 0 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/149: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1538: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1633: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/1841: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/188: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/249: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/265: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/352: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/386: 1 overlaps
Physiological And Pathological Hypertrophy Of The Heart WP1528 x https://identifiers.org/aop.events/890: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1115: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1271: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1392: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1457: 0 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/149: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1538: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1633: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/1841: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/188: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/249: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/265: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/352: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/386: 1 overlaps
Polycystic Kidney Disease Pathway WP2571 x https://identifiers.org/aop.events/890: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1115: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1271: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1392: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1457: 0 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/149: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1538: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1633: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/1841: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/188: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/249: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/265: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/352: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/386: 1 overlaps
Prolactin Signaling WP2037 x https://identifiers.org/aop.events/890: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1115: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1271: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1392: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1457: 0 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/149: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1538: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1633: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/1841: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/188: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/249: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/265: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/352: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/386: 1 overlaps
Quercetin And Nf kB AP 1 Induced Apoptosis WP2435 x https://identifiers.org/aop.events/890: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1115: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1271: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1392: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1457: 0 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/149: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1538: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1633: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/1841: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/188: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/249: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/265: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/352: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/386: 1 overlaps
RANKL RANK Signaling WP2018 x https://identifiers.org/aop.events/890: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1115: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1271: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1392: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1457: 0 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/149: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1538: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1633: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/1841: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/188: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/249: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/265: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/352: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/386: 1 overlaps
Selenium Metabolism And Selenoproteins WP28 x https://identifiers.org/aop.events/890: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1115: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1271: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1392: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1457: 0 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/149: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1538: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1633: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/1841: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/188: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/249: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/265: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/352: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/386: 1 overlaps
Senescence Associated Secretory Phenotype SASP WP3391 x https://identifiers.org/aop.events/890: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1115: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1271: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1392: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1457: 0 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/149: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1538: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1633: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/1841: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/188: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/249: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/265: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/352: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/386: 1 overlaps
Serotonin And Anxiety Related Events WP3944 x https://identifiers.org/aop.events/890: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1115: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1271: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1392: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1457: 0 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/149: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1538: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1633: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/1841: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/188: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/249: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/265: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/352: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/386: 1 overlaps
Serotonin And Anxiety WP3947 x https://identifiers.org/aop.events/890: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1115: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1271: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1392: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1457: 0 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/149: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1538: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1633: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/1841: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/188: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/249: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/265: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/352: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/386: 1 overlaps
Serotonin HTR1 Group And FOS Pathway WP722 x https://identifiers.org/aop.events/890: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1115: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1271: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1392: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1457: 0 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/149: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1538: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1633: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/1841: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/188: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/249: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/265: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/352: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/386: 1 overlaps
Sleep Regulation WP3591 x https://identifiers.org/aop.events/890: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1115: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1271: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1392: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1457: 0 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/149: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1538: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1633: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/1841: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/188: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/249: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/265: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/352: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/386: 1 overlaps
T Cell Activation SARS CoV 2 WP5098 x https://identifiers.org/aop.events/890: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1115: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1271: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1392: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1457: 0 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/149: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1538: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1633: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/1841: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/188: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/249: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/265: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/352: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/386: 1 overlaps
T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863 x https://identifiers.org/aop.events/890: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1115: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1271: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1392: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1457: 0 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/149: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1538: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1633: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/1841: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/188: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/249: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/265: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/352: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/386: 1 overlaps
T Cell Receptor Signaling WP69 x https://identifiers.org/aop.events/890: 1 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1115: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1271: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1392: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1457: 1 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/149: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1538: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1633: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/1841: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/188: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/249: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/265: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/352: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/386: 0 overlaps
TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859 x https://identifiers.org/aop.events/890: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1115: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1271: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1392: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1457: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/149: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1538: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1633: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1841: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/188: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/249: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/265: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/352: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/386: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/890: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1115: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1271: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1392: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1457: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/149: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1538: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1633: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1841: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/188: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/249: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/265: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/352: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/386: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/890: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1115: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1271: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1392: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1457: 0 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/149: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1538: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1633: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/1841: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/188: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/249: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/265: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/352: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/386: 1 overlaps
Th17 Cell Differentiation Pathway WP5130 x https://identifiers.org/aop.events/890: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1115: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1271: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1392: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1457: 0 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/149: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1538: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1633: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/1841: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/188: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/249: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/265: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/352: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/386: 1 overlaps
Toll Like Receptor Signaling WP75 x https://identifiers.org/aop.events/890: 1 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1115: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1271: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1392: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1457: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/149: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1538: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1633: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/1841: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/188: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/249: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/265: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/352: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/386: 0 overlaps
miR 517 Relationship With ARCN1 And USP1 WP3596 x https://identifiers.org/aop.events/890: 0 overlaps
title of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Cell Differentiation Expanded Index WP2023, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Corticotropin Releasing Hormone Signaling WP2355, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Development And Heterogeneity Of The ILC Family WP3893, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Endometrial Cancer WP4155, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'SNAI1'}, number: 1
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Estrogen Signaling WP712, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'SNAI1'}, number: 1
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Galanin Receptor Pathway WP4970, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'SNAI1'}, number: 1
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Hair Follicle Development Organogenesis Part 2 Of 3 WP2839, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hematopoietic SC Differentiation WP2849, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatitis B Infection WP4666, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Hepatocyte Growth Factor Receptor Signaling WP313, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human CoV Interferon Induction WP4880, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: ID Signaling WP53, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL3 Signaling WP286, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: IL4 Signaling WP395, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Interleukin 1 IL 1 Structural Pathway WP2637, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Pathway In Congenital Thyroid Cancer WP4928, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Melanoma WP4685, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'SNAI1'}, number: 1
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: NRP1 Triggered Signaling In Pancreatic Cancer WP5144, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration During Development WP4564, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neural Crest Cell Migration In Cancer WP4565, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Neurogenesis Regulation In The Olfactory Epithelium WP5265, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Neuroinflammation WP4919, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oncostatin M Signaling WP2374, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Osteoarthritic Chondrocyte Hypertrophy WP5373, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Oxidative Stress Response WP408, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGF Pathway WP2526, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: PDGFR Beta Pathway WP3972, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced AP 1 Survival Signaling WP3611, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Physiological And Pathological Hypertrophy Of The Heart WP1528, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Polycystic Kidney Disease Pathway WP2571, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Prolactin Signaling WP2037, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Quercetin And Nf kB AP 1 Induced Apoptosis WP2435, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: RANKL RANK Signaling WP2018, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Selenium Metabolism And Selenoproteins WP28, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Senescence Associated Secretory Phenotype SASP WP3391, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety Related Events WP3944, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin And Anxiety WP3947, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Serotonin HTR1 Group And FOS Pathway WP722, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Sleep Regulation WP3591, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Activation SARS CoV 2 WP5098, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: T Cell Receptor Signaling WP69, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'SNAI1'}, number: 1
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Th17 Cell Differentiation Pathway WP5130, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Toll Like Receptor Signaling WP75, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/1841, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/188, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/352, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: miR 517 Relationship With ARCN1 And USP1 WP3596, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Section 7.5.4 Tabulation gene overlap
In this section, a table is created that contains the number of overlapping genes and number of total genes in preparation for section 7.5.5.
final_geneoverlaptable_AGNP_24H=pd.DataFrame.from_dict(overlapping_genes_betweenORA_and_significantKEs3,orient='index')
Section 7.5.5 Percent overlap calculation
In this section, the percent overlap for the genesets are calculated.
Step 41. Lastly, the percent overlap is calculated and add the result as a column to the dataframe. This is first done by running a for loop to calculate the total number of genes belonging to the enriched pathways of ORA.
variable_count3= {}
for index, row in exploded_df3_ORApathwaytable.iterrows():
unique_KE = row['Term']
gene_expression_value = row['Genes']
if unique_KE not in variable_count3:
variable_count3[unique_KE] = 1
else:
variable_count3[unique_KE] += 1
print("The total number of genes: ")
print(variable_count3)
The total number of genes:
{'Hepatitis B Infection WP4666': 2, 'Epithelial To Mesenchymal Transition In Colorectal Cancer WP4239': 2, 'miR 517 Relationship With ARCN1 And USP1 WP3596': 1, 'Circadian Rhythm Genes WP3594': 2, 'Neuroinflammation WP4919': 1, 'Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892': 1, 'Serotonin And Anxiety Related Events WP3944': 1, 'MAPK Pathway In Congenital Thyroid Cancer WP4928': 1, 'Quercetin And Nf kB AP 1 Induced Apoptosis WP2435': 1, 'ID Signaling WP53': 1, 'Galanin Receptor Pathway WP4970': 1, 'TGF Beta In Thyroid Cells For Epithelial Mesenchymal Transition WP3859': 1, 'Serotonin And Anxiety WP3947': 1, 'Cell Differentiation Expanded Index WP2023': 1, 'Estrogen Signaling WP712': 1, 'Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612': 1, 'Physiological And Pathological Hypertrophy Of The Heart WP1528': 1, 'FGFR3 Signal Chondrocyte Proliferation Terminal Differentiation WP4767': 1, 'PDGFR Beta Pathway WP3972': 1, 'Host Pathogen Interaction Of Human CoV Interferon Induction WP4880': 1, 'Hair Follicle Development Organogenesis Part 2 Of 3 WP2839': 1, 'Development And Heterogeneity Of The ILC Family WP3893': 1, 'Oxidative Stress Response WP408': 1, 'Selenium Metabolism And Selenoproteins WP28': 1, 'Hepatocyte Growth Factor Receptor Signaling WP313': 1, 'Host Pathogen Interaction Of Human Coronaviruses MAPK Signaling WP4877': 1, 'Serotonin HTR1 Group And FOS Pathway WP722': 1, 'Sleep Regulation WP3591': 1, 'Neural Crest Cell Migration During Development WP4564': 1, 'PDGF Pathway WP2526': 1, 'Neural Crest Cell Migration In Cancer WP4565': 1, 'Osteoarthritic Chondrocyte Hypertrophy WP5373': 1, 'Interleukin 1 IL 1 Structural Pathway WP2637': 1, 'RANKL RANK Signaling WP2018': 1, 'IL3 Signaling WP286': 1, 'Senescence Associated Secretory Phenotype SASP WP3391': 1, 'Photodynamic Therapy Induced AP 1 Survival Signaling WP3611': 1, 'IL4 Signaling WP395': 1, 'NRP1 Triggered Signaling In Pancreatic Cancer WP5144': 1, 'Neurogenesis Regulation In The Olfactory Epithelium WP5265': 1, 'TGF Beta Receptor Signaling WP560': 1, 'Hematopoietic SC Differentiation WP2849': 1, 'Oncostatin M Signaling WP2374': 1, 'TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816': 1, 'T Cell Antigen Receptor TCR Pathway During Staph A. Infection WP3863': 1, 'Endometrial Cancer WP4155': 1, 'Melanoma WP4685': 1, 'Th17 Cell Differentiation Pathway WP5130': 1, 'Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216': 1, 'Prolactin Signaling WP2037': 1, 'T Cell Receptor Signaling WP69': 1, 'T Cell Activation SARS CoV 2 WP5098': 1, 'Polycystic Kidney Disease Pathway WP2571': 1, 'Hair Follicle Development Cytodifferentiation Stage 3 Of 3 WP2840': 1, 'Apoptosis Modulation And Signaling WP1772': 1, 'Toll Like Receptor Signaling WP75': 1, 'Corticotropin Releasing Hormone Signaling WP2355': 1}
Step 42. The result is converted into a dataframe and added to the final dataframe. This is followed by some data manipulation prior to calculation of gene set overlap.
variable_count_df3=pd.DataFrame.from_dict(variable_count3,orient='index')
reset_variable_count_df3 = variable_count_df3.reset_index()
reset_variable_count_df3.columns = ['Term', 'Total number of genes']
Genesetoverlaptable_AGNP24H=final_geneoverlaptable_AGNP_24H.reset_index(level=[1])
Genesetoverlaptable_AGNP24H.reset_index(inplace=True)
Genesetoverlaptable_AGNP24H.columns= ['Term','KEID','overlapping genes','number of genes that overlap']
tabulation_C3=pd.merge(reset_variable_count_df3,Genesetoverlaptable_AGNP24H, on='Term')
def calculate_Genesetoverlap_Score(row):
return f"{(row['number of genes that overlap']/row['Total number of genes'])*100}"
tabulation_C3.loc[:,'Percent geneset overlap']= tabulation_C3.apply(calculate_Genesetoverlap_Score, axis=1)
tabulation_C3
Term | Total number of genes | KEID | overlapping genes | number of genes that overlap | Percent geneset overlap | |
---|---|---|---|---|---|---|
0 | Hepatitis B Infection WP4666 | 2 | https://identifiers.org/aop.events/1115 | {FOS} | 1 | 50.0 |
1 | Hepatitis B Infection WP4666 | 2 | https://identifiers.org/aop.events/1271 | {FOS} | 1 | 50.0 |
2 | Hepatitis B Infection WP4666 | 2 | https://identifiers.org/aop.events/1392 | {FOS} | 1 | 50.0 |
3 | Hepatitis B Infection WP4666 | 2 | https://identifiers.org/aop.events/1457 | {} | 0 | 0.0 |
4 | Hepatitis B Infection WP4666 | 2 | https://identifiers.org/aop.events/149 | {FOS} | 1 | 50.0 |
... | ... | ... | ... | ... | ... | ... |
793 | Corticotropin Releasing Hormone Signaling WP2355 | 1 | https://identifiers.org/aop.events/249 | {FOS} | 1 | 100.0 |
794 | Corticotropin Releasing Hormone Signaling WP2355 | 1 | https://identifiers.org/aop.events/265 | {FOS} | 1 | 100.0 |
795 | Corticotropin Releasing Hormone Signaling WP2355 | 1 | https://identifiers.org/aop.events/352 | {FOS} | 1 | 100.0 |
796 | Corticotropin Releasing Hormone Signaling WP2355 | 1 | https://identifiers.org/aop.events/386 | {FOS} | 1 | 100.0 |
797 | Corticotropin Releasing Hormone Signaling WP2355 | 1 | https://identifiers.org/aop.events/890 | {FOS} | 1 | 100.0 |
798 rows × 6 columns
Section 8. Comparison 4: Chloropicrin timepoint 2
Section 8.1 Calculation of n variable
In this section, variable n will be calculated for the comparison:4.
Step 43. The table containing the differential expressed genes for comparison 4 is loaded with the filter for significance.
Comparison4_DEG= pd.read_csv("C:/Users/shaki/Downloads/DEG tables-all expressed genes/de_genes_CP.24h.tsv",sep='\t',dtype={'GENE':'string'})
The_comparison4_DEG=Comparison4_DEG.dropna(subset=['GENE_SYMBOL'])
The_Comparison4_DEG=The_comparison4_DEG.drop_duplicates(subset=['GENE'])
Comparison_4_DEG= The_Comparison4_DEG[The_Comparison4_DEG['adj.P.Val'] < 0.05]
The_comparison_4_DEG=Comparison_4_DEG.copy()
Comparison4=The_comparison_4_DEG.rename(columns={'GENE':'GENEID'})
Comparison4['GENEID'] = Comparison4['GENEID'].astype(str)
Comparison_4=Comparison4.drop(columns=['SPOT_ID','COL','ROW','NAME','ACCESSION_STRING','CHROMOSOMAL_LOCATION','CYTOBAND','ORDER','ENSEMBL_ID','SPOT_ID.1','UNIGENE_ID','TIGR_ID','GO_ID','DESCRIPTION','SEQUENCE','CONTROL_TYPE','REFSEQ','GB_ACC'])
Comparison_4
ID | GENEID | GENE_SYMBOL | GENE_NAME | logFC | AveExpr | t | P.Value | adj.P.Val | B | |
---|---|---|---|---|---|---|---|---|---|---|
0 | 2985 | 26471 | NUPR1 | nuclear protein 1 | -0.569941 | 0.167603 | -10.048946 | 1.026382e-14 | 4.620257e-10 | 22.754357 |
1 | 26605 | 1960 | EGR3 | early growth response 3 | -1.036190 | 0.094340 | -9.547580 | 7.333753e-14 | 1.650645e-09 | 21.111511 |
2 | 20886 | 4312 | MMP1 | matrix metallopeptidase 1 (interstitial collag... | 1.110417 | 0.336235 | 9.060676 | 5.051693e-13 | 7.580066e-09 | 19.484600 |
3 | 28401 | 3491 | CYR61 | cysteine-rich, angiogenic inducer, 61 | -0.553970 | 0.039803 | -8.629276 | 2.830410e-12 | 3.185273e-08 | 18.020317 |
5 | 5593 | 7286 | TUFT1 | tuftelin 1 | -0.534234 | 0.037927 | -8.244738 | 1.325546e-11 | 8.352296e-08 | 16.699787 |
... | ... | ... | ... | ... | ... | ... | ... | ... | ... | ... |
1241 | 8174 | 158 | ADSL | adenylosuccinate lyase | 0.179203 | -0.019468 | 3.352330 | 1.358681e-03 | 4.924398e-02 | 0.587786 |
1242 | 41584 | 29968 | PSAT1 | phosphoserine aminotransferase 1 | -0.299535 | 0.189610 | -3.351153 | 1.363585e-03 | 4.938195e-02 | 0.584680 |
1247 | 7523 | 51300 | C3orf1 | chromosome 3 open reading frame 1 | 0.104950 | 0.041448 | 3.348029 | 1.376679e-03 | 4.965340e-02 | 0.576441 |
1248 | 10867 | 124790 | HEXIM2 | hexamthylene bis-acetamide inducible 2 | 0.177600 | -0.062051 | 3.347787 | 1.377699e-03 | 4.965340e-02 | 0.575803 |
1249 | 43883 | 29953 | TRHDE | thyrotropin-releasing hormone degrading enzyme | -0.170322 | -0.008790 | -3.347479 | 1.378996e-03 | 4.966040e-02 | 0.574992 |
817 rows × 10 columns
Step 44. Here, the results of the DEG table are integrated into the mergeddataframe dataframe. This is followed by adjustment of the dataframe columns to remove non-relevant columns.
merged_dataframe_DEG_C4= pd.merge(mergeddataframe,Comparison_4, on='GENEID')
Step 45. The following for loop for the key events to retrieve the n variable. It is comparable to the for loop of N, but adds a condition to check for significance of genes by p adjusted value being smaller than 0.05.
variable_n_dictionary_count4= {}
for index, row in merged_dataframe_DEG_C4.iterrows():
unique_KE = row['KEID']
gene_expression_value = row['adj.P.Val']
if gene_expression_value < 0.05:
if unique_KE not in variable_n_dictionary_count4:
variable_n_dictionary_count4[unique_KE] = 1
else:
variable_n_dictionary_count4[unique_KE] += 1
print("The total number of significant genes: ")
print(variable_n_dictionary_count4)
The total number of significant genes:
{'https://identifiers.org/aop.events/486': 7, 'https://identifiers.org/aop.events/875': 13, 'https://identifiers.org/aop.events/2007': 11, 'https://identifiers.org/aop.events/1495': 7, 'https://identifiers.org/aop.events/1668 ': 5, 'https://identifiers.org/aop.events/244 ': 45, 'https://identifiers.org/aop.events/1814 ': 23, 'https://identifiers.org/aop.events/888': 1, 'https://identifiers.org/aop.events/41': 25, 'https://identifiers.org/aop.events/1270': 9, 'https://identifiers.org/aop.events/1086': 4, 'https://identifiers.org/aop.events/1487 ': 2, 'https://identifiers.org/aop.events/1539': 10, 'https://identifiers.org/aop.events/201': 1, 'https://identifiers.org/aop.events/457': 35, 'https://identifiers.org/aop.events/55': 8, 'https://identifiers.org/aop.events/188': 1, 'https://identifiers.org/aop.events/618': 14, 'https://identifiers.org/aop.events/389': 1, 'https://identifiers.org/aop.events/2013': 5, 'https://identifiers.org/aop.events/2006': 16, 'https://identifiers.org/aop.events/1497': 30, 'https://identifiers.org/aop.events/870': 1, 'https://identifiers.org/aop.events/1669': 27, 'https://identifiers.org/aop.events/1115': 5, 'https://identifiers.org/aop.events/202': 8, 'https://identifiers.org/aop.events/1917': 22, 'https://identifiers.org/aop.events/1633': 60, 'https://identifiers.org/aop.events/1392': 15, 'https://identifiers.org/aop.events/1815': 14, 'https://identifiers.org/aop.events/386': 23, 'https://identifiers.org/aop.events/1582': 2, 'https://identifiers.org/aop.events/1896': 14, 'https://identifiers.org/aop.events/1172': 1, 'https://identifiers.org/aop.events/1496': 24, 'https://identifiers.org/aop.events/68': 12, 'https://identifiers.org/aop.events/1493': 48, 'https://identifiers.org/aop.events/265': 19, 'https://identifiers.org/aop.events/1817': 14, 'https://identifiers.org/aop.events/1819': 1, 'https://identifiers.org/aop.events/1750': 30, 'https://identifiers.org/aop.events/1848': 7, 'https://identifiers.org/aop.events/1365': 14, 'https://identifiers.org/aop.events/890': 5, 'https://identifiers.org/aop.events/1587': 6, 'https://identifiers.org/aop.events/1457': 4, 'https://identifiers.org/aop.events/1586': 3, 'https://identifiers.org/aop.events/149': 60, 'https://identifiers.org/aop.events/1575': 14, 'https://identifiers.org/aop.events/1579': 9, 'https://identifiers.org/aop.events/87': 12, 'https://identifiers.org/aop.events/249': 5, 'https://identifiers.org/aop.events/288': 3, 'https://identifiers.org/aop.events/209': 53, 'https://identifiers.org/aop.events/1498': 19, 'https://identifiers.org/aop.events/1499': 3, 'https://identifiers.org/aop.events/1500': 17, 'https://identifiers.org/aop.events/1488': 14, 'https://identifiers.org/aop.events/1494': 6, 'https://identifiers.org/aop.events/52': 16, 'https://identifiers.org/aop.events/381': 10, 'https://identifiers.org/aop.events/484': 28, 'https://identifiers.org/aop.events/388': 13, 'https://identifiers.org/aop.events/1262': 14, 'https://identifiers.org/aop.events/1945': 40, 'https://identifiers.org/aop.events/2009': 6, 'https://identifiers.org/aop.events/2012': 17, 'https://identifiers.org/aop.events/1818': 10, 'https://identifiers.org/aop.events/1752': 7, 'https://identifiers.org/aop.events/887': 1, 'https://identifiers.org/aop.events/1585': 7, 'https://identifiers.org/aop.events/214': 1, 'https://identifiers.org/aop.events/1271': 11, 'https://identifiers.org/aop.events/1087': 30, 'https://identifiers.org/aop.events/1538': 5, 'https://identifiers.org/aop.events/898': 14, 'https://identifiers.org/aop.events/195': 14, 'https://identifiers.org/aop.events/459': 5, 'https://identifiers.org/aop.events/1670': 3, 'https://identifiers.org/aop.events/1090': 21, 'https://identifiers.org/aop.events/344': 2, 'https://identifiers.org/aop.events/1841': 1, 'https://identifiers.org/aop.events/1820': 6, 'https://identifiers.org/aop.events/896': 2, 'https://identifiers.org/aop.events/1549': 7, 'https://identifiers.org/aop.events/352': 20}
Step 46. The output of the n variable dictionary is saved as a dataframe and integrated as a separate column into a dataframe.
n_variable_dataframe4=pd.DataFrame.from_dict(variable_n_dictionary_count4,orient='index')
n_variable_dataframe4
0 | |
---|---|
https://identifiers.org/aop.events/486 | 7 |
https://identifiers.org/aop.events/875 | 13 |
https://identifiers.org/aop.events/2007 | 11 |
https://identifiers.org/aop.events/1495 | 7 |
https://identifiers.org/aop.events/1668 | 5 |
... | ... |
https://identifiers.org/aop.events/1841 | 1 |
https://identifiers.org/aop.events/1820 | 6 |
https://identifiers.org/aop.events/896 | 2 |
https://identifiers.org/aop.events/1549 | 7 |
https://identifiers.org/aop.events/352 | 20 |
86 rows × 1 columns
n_variable_dataframe4_reset = n_variable_dataframe4.reset_index()
n_variable_dataframe4_reset.columns = ['KEID', 'n']
n_variable_dataframe4_reset
KEID | n | |
---|---|---|
0 | https://identifiers.org/aop.events/486 | 7 |
1 | https://identifiers.org/aop.events/875 | 13 |
2 | https://identifiers.org/aop.events/2007 | 11 |
3 | https://identifiers.org/aop.events/1495 | 7 |
4 | https://identifiers.org/aop.events/1668 | 5 |
... | ... | ... |
81 | https://identifiers.org/aop.events/1841 | 1 |
82 | https://identifiers.org/aop.events/1820 | 6 |
83 | https://identifiers.org/aop.events/896 | 2 |
84 | https://identifiers.org/aop.events/1549 | 7 |
85 | https://identifiers.org/aop.events/352 | 20 |
86 rows × 2 columns
merged_dataframe4= pd.merge(mergeddataframe, n_variable_dataframe4_reset, on='KEID')
Section 8.2. Calculation of variable B and variable b.
In this section, variable B and variable b are calculated.
Step 47. Variable B is calculated by taking the length of the dataframe which includes all genes in 1 DEG table.
B=len(The_Comparison4_DEG.index)
B
19751
Step 48. Variable b is calculated by taking the length of the dataframe which includes all genes in 1 DEG table with the condition for significance.
The_Comparison4_DEG_filtered=The_Comparison4_DEG[The_Comparison4_DEG['adj.P.Val'] < 0.05]
b=len(The_Comparison4_DEG_filtered)
b
817
Section 8.3. Calculation of enrichment score and hypergeometric p-value
In this section, the enrichment score and hypergeometric p-value will be calculated. This requires the four variables of the enrichment score per KE for which the formula will be applied to and stored in an additional dataframe.
Step 49. The final dataframe will be created that contains the KEID and the four variables: variable N, variable n, variable B and variable b.
Final_dataframe_ES_C4= merged_dataframe4.loc[:, ['KEID','N','n']]
Final_dataframe_ES_C4['B']=pd.Series([19751 for x in range(len(Final_dataframe_ES_C4.index))])
Final_dataframe_ES_C4['b']=pd.Series([817 for x in range(len(Final_dataframe_ES_C4.index))])
Final_Dataframe_ESC4=Final_dataframe_ES_C4.drop_duplicates(subset=['KEID'],keep='first')
Final_Dataframe_ESC4.reset_index(drop=True,inplace=True)
Final_Dataframe_ESC4.copy()
KEID | N | n | B | b | |
---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/486 | 129 | 7 | 19751 | 817 |
1 | https://identifiers.org/aop.events/875 | 169 | 13 | 19751 | 817 |
2 | https://identifiers.org/aop.events/2007 | 184 | 11 | 19751 | 817 |
3 | https://identifiers.org/aop.events/1495 | 253 | 7 | 19751 | 817 |
4 | https://identifiers.org/aop.events/1668 | 156 | 5 | 19751 | 817 |
... | ... | ... | ... | ... | ... |
81 | https://identifiers.org/aop.events/1841 | 17 | 1 | 19751 | 817 |
82 | https://identifiers.org/aop.events/1820 | 57 | 6 | 19751 | 817 |
83 | https://identifiers.org/aop.events/896 | 82 | 2 | 19751 | 817 |
84 | https://identifiers.org/aop.events/1549 | 101 | 7 | 19751 | 817 |
85 | https://identifiers.org/aop.events/352 | 398 | 20 | 19751 | 817 |
86 rows × 5 columns
Step 50. The follow for loop will be used to calculate the enrichment score for individual key events and the results will be saved as a separate column into the dataframe.
def calculate_Enrichment_Score(row):
return f"{(row['n']/row['N'])/(row['b']/row['B'])}"
Final_Dataframe_ESC4.loc[:,'Enrichmentscore']= Final_Dataframe_ESC4.apply(calculate_Enrichment_Score,axis=1)
Final_Dataframe_ESC4
C:\Users\shaki\AppData\Local\Temp\ipykernel_11124\287210224.py:4: SettingWithCopyWarning:
A value is trying to be set on a copy of a slice from a DataFrame.
Try using .loc[row_indexer,col_indexer] = value instead
See the caveats in the documentation: https://pandas.pydata.org/pandas-docs/stable/user_guide/indexing.html#returning-a-view-versus-a-copy
Final_Dataframe_ESC4.loc[:,'Enrichmentscore']= Final_Dataframe_ESC4.apply(calculate_Enrichment_Score,axis=1)
KEID | N | n | B | b | Enrichmentscore | |
---|---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/486 | 129 | 7 | 19751 | 817 | 1.3118233658781893 |
1 | https://identifiers.org/aop.events/875 | 169 | 13 | 19751 | 817 | 1.859617738442708 |
2 | https://identifiers.org/aop.events/2007 | 184 | 11 | 19751 | 817 | 1.4452463945505827 |
3 | https://identifiers.org/aop.events/1495 | 253 | 7 | 19751 | 817 | 0.6688743644201044 |
4 | https://identifiers.org/aop.events/1668 | 156 | 5 | 19751 | 817 | 0.7748407243511282 |
... | ... | ... | ... | ... | ... | ... |
81 | https://identifiers.org/aop.events/1841 | 17 | 1 | 19751 | 817 | 1.4220606235150117 |
82 | https://identifiers.org/aop.events/1820 | 57 | 6 | 19751 | 817 | 2.544740063132126 |
83 | https://identifiers.org/aop.events/896 | 82 | 2 | 19751 | 817 | 0.5896348926769561 |
84 | https://identifiers.org/aop.events/1549 | 101 | 7 | 19751 | 817 | 1.6754971702800636 |
85 | https://identifiers.org/aop.events/352 | 398 | 20 | 19751 | 817 | 1.214825658279156 |
86 rows × 6 columns
Step 51. The following for loop will be used to calculate the hypergeometric p-value for individual Key Events and save the result as a separate column into the dataframe. This requires some in between steps for manipulation of the dataframe.
p_value_dataframe4=[]
for index, row in Final_Dataframe_ESC4.iterrows():
M = row['B']
n = row['b']
N = row['N']
k = row['n']
hpd = ss.hypergeom(M, n, N)
p = hpd.pmf(k)
p_value_dataframe4.append(p)
Hypergeometricpvalue_dataframe4=pd.DataFrame(p_value_dataframe4)
Hypergeometricpvalue_dataframe4.columns= ['Hypergeometric p-value']
Hypergeometricpvalue_dataframe4
Hypergeometric p-value | |
---|---|
0 | 0.119946 |
1 | 0.012886 |
2 | 0.061397 |
3 | 0.076689 |
4 | 0.148560 |
... | ... |
81 | 0.357909 |
82 | 0.020977 |
83 | 0.193556 |
84 | 0.067139 |
85 | 0.063115 |
86 rows × 1 columns
merged_finaltable4=pd.concat([Final_Dataframe_ESC4,Hypergeometricpvalue_dataframe4],axis=1)
Section 8.4. Filtering the results for significant KEs
In this section, the results will be filtered to only include significant KEs. Significant KEs have an enrichment score above 1 and a hypergeometric p-value below 0.05.
Step 52. Lastly, we filter the results to showcase the significant KEs for the comparison: Bisphenol A 1uM.
filteredversion_C4= merged_finaltable4[(merged_finaltable4['Enrichmentscore']>str(1))& (merged_finaltable4['Hypergeometric p-value'] < 0.05)]
KEID | N | n | B | b | Enrichmentscore | Hypergeometric p-value | |
---|---|---|---|---|---|---|---|
1 | https://identifiers.org/aop.events/875 | 169 | 13 | 19751 | 817 | 1.859617738442708 | 1.288550e-02 |
5 | https://identifiers.org/aop.events/244 | 417 | 45 | 19751 | 817 | 2.608816251772144 | 2.974309e-09 |
6 | https://identifiers.org/aop.events/1814 | 251 | 23 | 19751 | 817 | 2.2152418477863334 | 1.946143e-04 |
8 | https://identifiers.org/aop.events/41 | 275 | 25 | 19751 | 817 | 2.1977300545232 | 1.222983e-04 |
9 | https://identifiers.org/aop.events/1270 | 72 | 9 | 19751 | 817 | 3.0218788249694 | 2.070479e-03 |
14 | https://identifiers.org/aop.events/457 | 584 | 35 | 19751 | 817 | 1.44884601197163 | 6.985699e-03 |
20 | https://identifiers.org/aop.events/2006 | 216 | 16 | 19751 | 817 | 1.790743007389274 | 9.339910e-03 |
21 | https://identifiers.org/aop.events/1497 | 528 | 30 | 19751 | 817 | 1.373581284077 | 1.745922e-02 |
23 | https://identifiers.org/aop.events/1669 | 400 | 27 | 19751 | 817 | 1.6318145654834761 | 4.080562e-03 |
24 | https://identifiers.org/aop.events/1115 | 34 | 5 | 19751 | 817 | 3.5551515587875295 | 9.845877e-03 |
26 | https://identifiers.org/aop.events/1917 | 166 | 22 | 19751 | 817 | 3.203919718039846 | 1.058442e-06 |
27 | https://identifiers.org/aop.events/1633 | 1056 | 60 | 19751 | 817 | 1.373581284077 | 2.631061e-03 |
28 | https://identifiers.org/aop.events/1392 | 102 | 15 | 19751 | 817 | 3.5551515587875295 | 1.469958e-05 |
29 | https://identifiers.org/aop.events/1815 | 58 | 14 | 19751 | 817 | 5.835352213734014 | 6.277622e-08 |
30 | https://identifiers.org/aop.events/386 | 372 | 23 | 19751 | 817 | 1.494692752135402 | 1.505654e-02 |
32 | https://identifiers.org/aop.events/1896 | 205 | 14 | 19751 | 817 | 1.6509776994954772 | 2.242621e-02 |
34 | https://identifiers.org/aop.events/1496 | 406 | 24 | 19751 | 817 | 1.4290658482613912 | 1.964315e-02 |
35 | https://identifiers.org/aop.events/68 | 64 | 12 | 19751 | 817 | 4.5328182374541 | 8.723329e-06 |
36 | https://identifiers.org/aop.events/1493 | 812 | 48 | 19751 | 817 | 1.4290658482613912 | 3.043754e-03 |
37 | https://identifiers.org/aop.events/265 | 268 | 19 | 19751 | 817 | 1.7139014231169731 | 7.958032e-03 |
40 | https://identifiers.org/aop.events/1750 | 528 | 30 | 19751 | 817 | 1.373581284077 | 1.745922e-02 |
43 | https://identifiers.org/aop.events/890 | 34 | 5 | 19751 | 817 | 3.5551515587875295 | 9.845877e-03 |
44 | https://identifiers.org/aop.events/1587 | 57 | 6 | 19751 | 817 | 2.544740063132126 | 2.097712e-02 |
45 | https://identifiers.org/aop.events/1457 | 19 | 4 | 19751 | 817 | 5.089480126264252 | 5.996158e-03 |
47 | https://identifiers.org/aop.events/149 | 1056 | 60 | 19751 | 817 | 1.373581284077 | 2.631061e-03 |
50 | https://identifiers.org/aop.events/87 | 114 | 12 | 19751 | 817 | 2.544740063132126 | 1.814258e-03 |
51 | https://identifiers.org/aop.events/249 | 34 | 5 | 19751 | 817 | 3.5551515587875295 | 9.845877e-03 |
53 | https://identifiers.org/aop.events/209 | 617 | 53 | 19751 | 817 | 2.0766233740470432 | 2.427794e-07 |
54 | https://identifiers.org/aop.events/1498 | 224 | 19 | 19751 | 817 | 2.050560631229236 | 1.451532e-03 |
56 | https://identifiers.org/aop.events/1500 | 260 | 17 | 19751 | 817 | 1.5806750776763017 | 1.946979e-02 |
57 | https://identifiers.org/aop.events/1488 | 184 | 14 | 19751 | 817 | 1.8394045021552872 | 1.129656e-02 |
59 | https://identifiers.org/aop.events/52 | 219 | 16 | 19751 | 817 | 1.7662122812606538 | 1.035400e-02 |
62 | https://identifiers.org/aop.events/388 | 169 | 13 | 19751 | 817 | 1.859617738442708 | 1.288550e-02 |
66 | https://identifiers.org/aop.events/2012 | 260 | 17 | 19751 | 817 | 1.5806750776763017 | 1.946979e-02 |
70 | https://identifiers.org/aop.events/1585 | 35 | 7 | 19751 | 817 | 4.83500611995104 | 4.203466e-04 |
72 | https://identifiers.org/aop.events/1271 | 58 | 11 | 19751 | 817 | 4.584919596505296 | 1.820621e-05 |
73 | https://identifiers.org/aop.events/1087 | 528 | 30 | 19751 | 817 | 1.373581284077 | 1.745922e-02 |
74 | https://identifiers.org/aop.events/1538 | 34 | 5 | 19751 | 817 | 3.5551515587875295 | 9.845877e-03 |
76 | https://identifiers.org/aop.events/195 | 184 | 14 | 19751 | 817 | 1.8394045021552872 | 1.129656e-02 |
82 | https://identifiers.org/aop.events/1820 | 57 | 6 | 19751 | 817 | 2.544740063132126 | 2.097712e-02 |
Section 8.5. Calculation of percent gene overlap to ORA
Section 8.5.1 Creation of the significant KEs table
In this section, you merge the dataframes to retrieve the genes connected to only the significant KEs.
Step 53. The significant KE table is created using the significan KEs from the previous merggeddataframe_final.
mergeddataframe_final2=mergeddataframe_final.copy()
mergeddataframe_final2['KEID'] = mergeddataframe_final2['KEID'].str.strip()
significantKEID_genetable4=mergeddataframe_final2[(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/875')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/244')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1814')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/41')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1270')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/475')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/2006')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1497')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1669')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1115')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1917')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1633')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1392')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1815')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/386')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1896')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1496')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/68')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1493')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/265')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1750')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/890')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1587')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1457')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/149')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/87')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/249')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/209')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1498')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1500')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1488')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/52')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/388')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/2012')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1585')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1271')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1087')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1538')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/195')|(mergeddataframe_final2['KEID'] =='https://identifiers.org/aop.events/1820')]
significantKEIDgenetable4=significantKEID_genetable4.drop(columns={'WPtitle','ID'})
Section 8.5.2 Significant ORA pathway table plus splitting
In this section, the significant ORA pathway table is created.
Step 54. The significant ORA pathway table is created using the significant enriched patwhays identified from the ORA analysis. This requires data manipulation to restructure the table in a way that the individual genes for the enriched pathways are placed on individual rows.
datafile_ORA4 = pd.read_csv("C:/Users/shaki/Downloads/GSE44729_ORApathwaytable/Comparison 4-CP timepoint 2.txt", sep='\t')
datafileORA4=pd.DataFrame(datafile_ORA4)
filtereddatafileORA_4=datafileORA4[datafileORA4['Adjusted P-value'] < 0.05]
Gene_set | Term | P-value | Adjusted P-value | Old P-value | Old adjusted P-value | Odds Ratio | Combined Score | Genes | |
---|---|---|---|---|---|---|---|---|---|
0 | WikiPathways_2024_Human | Nuclear Receptors Meta Pathway WP2882 | 2.094434e-10 | 1.055595e-07 | 0 | 0 | 4.727137 | 105.35170 | TNFAIP3;GCC1;SLC7A11;CYP3A5;DNAJB1;RGS2;CCND1;... |
1 | WikiPathways_2024_Human | Photodynamic Therapy Induced Unfolded Protein ... | 4.496800e-08 | 1.133194e-05 | 0 | 0 | 20.965630 | 354.68220 | PPP1R15A;XBP1;DDIT3;DNAJB9;ASNS;TRIB3;CALR;ATF4 |
2 | WikiPathways_2024_Human | TGF Beta Signaling Pathway WP366 | 2.190049e-07 | 3.679283e-05 | 0 | 0 | 5.876607 | 90.11291 | CDKN2B;MMP1;LIMK2;TNC;FOS;THBS1;RUNX2;PML;SMAD... |
3 | WikiPathways_2024_Human | P53 Transcriptional Gene Network WP4963 | 2.046127e-06 | 2.578120e-04 | 0 | 0 | 6.931117 | 90.79459 | PCNA;ADORA2B;SESN1;SESN2;PMAIP1;SLC7A11;ULBP2;... |
4 | WikiPathways_2024_Human | TGF Beta Receptor Signaling WP560 | 2.776715e-06 | 2.798929e-04 | 0 | 0 | 8.918056 | 114.09980 | SKI;BAMBI;FST;FOS;LTBP1;THBS1;RUNX2;TGFBR2;SMAD7 |
5 | WikiPathways_2024_Human | TGF Beta Receptor Signaling In Skeletal Dyspla... | 5.138286e-06 | 4.316160e-04 | 0 | 0 | 8.188350 | 99.72421 | SKI;BAMBI;FST;FOS;LTBP1;THBS1;RUNX2;TGFBR2;SMAD7 |
6 | WikiPathways_2024_Human | Endoplasmic Reticulum Stress Response In Coron... | 6.058878e-06 | 4.362392e-04 | 0 | 0 | 9.622870 | 115.60900 | PPP1R15A;PPP1R15B;PPP1R14B;XBP1;PPP1R10;PPP1R3... |
7 | WikiPathways_2024_Human | NRF2 Pathway WP2884 | 9.824840e-06 | 6.189649e-04 | 0 | 0 | 4.816386 | 55.53581 | NQO1;SLC7A11;PRDX6;TGFBR2;DNAJB1;MAFF;ME1;HMOX... |
8 | WikiPathways_2024_Human | Macrophage Markers WP4146 | 2.827434e-05 | 1.583363e-03 | 0 | 0 | 35.337300 | 370.10720 | CD83;RAC2;CD14;F3 |
9 | WikiPathways_2024_Human | Unfolded Protein Response WP4925 | 1.044075e-04 | 5.262139e-03 | 0 | 0 | 13.013360 | 119.29620 | PPP1R15A;XBP1;DDIT3;PMAIP1;ATF4 |
10 | WikiPathways_2024_Human | Transcriptional Activation By NRF2 In Response... | 2.055268e-04 | 9.416864e-03 | 0 | 0 | 17.664070 | 149.96680 | NQO1;HMOX1;SLC7A11;GCLM |
11 | WikiPathways_2024_Human | Antiviral And Anti-Inflam Effects Of Nrf2 On S... | 3.489586e-04 | 1.303312e-02 | 0 | 0 | 9.615576 | 76.54535 | NQO1;MMP1;HMOX1;SLC7A11;GCLM |
12 | WikiPathways_2024_Human | mRNA Protein And Metabolite Inducation Pathway... | 3.620311e-04 | 1.303312e-02 | 0 | 0 | 33.054790 | 261.91890 | SLC7A5;SLC7A11;ATF4 |
13 | WikiPathways_2024_Human | Amino Acid Metabolism In Triple Negative Breas... | 3.620311e-04 | 1.303312e-02 | 0 | 0 | 33.054790 | 261.91890 | PSAT1;PHGDH;SLC7A11 |
14 | WikiPathways_2024_Human | Metabolic Pathways Of Fibroblasts WP5312 | 4.877618e-04 | 1.510736e-02 | 0 | 0 | 8.845413 | 67.45232 | UGDH;PSAT1;SERPINH1;PYCR1;PHGDH |
15 | WikiPathways_2024_Human | Ferroptosis WP4313 | 4.968782e-04 | 1.510736e-02 | 0 | 0 | 5.544931 | 42.18121 | MAP1LC3B;CTH;HSPB1;HMOX1;SLC7A11;GCLM;SAT1 |
16 | WikiPathways_2024_Human | miRNA Regulation Of DNA Damage Response WP1530 | 5.473470e-04 | 1.510736e-02 | 0 | 0 | 5.447368 | 40.91207 | RAD52;CCND1;GADD45B;SESN1;PMAIP1;PML;DDB2 |
17 | WikiPathways_2024_Human | DNA Damage Response WP707 | 5.473470e-04 | 1.510736e-02 | 0 | 0 | 5.447368 | 40.91207 | RAD52;CCND1;GADD45B;SESN1;PMAIP1;PML;DDB2 |
18 | WikiPathways_2024_Human | Adipogenesis WP236 | 5.695234e-04 | 1.510736e-02 | 0 | 0 | 3.805699 | 28.43128 | CYP26B1;KLF6;GADD45B;SCD;DDIT3;LEP;ID3;TRIB3;P... |
19 | WikiPathways_2024_Human | Glucocorticoid Receptor Pathway WP2880 | 6.604864e-04 | 1.585167e-02 | 0 | 0 | 5.262165 | 38.53238 | IL11;RGS2;GADD45B;DNER;TNFAIP3;SPRY1;TNS4 |
20 | WikiPathways_2024_Human | PPAR Signaling WP3942 | 6.604864e-04 | 1.585167e-02 | 0 | 0 | 5.262165 | 38.53238 | ACOX2;FABP5;MMP1;SCD;ME1;PPARD;PCK2 |
21 | WikiPathways_2024_Human | MAPK Signaling WP382 | 9.731422e-04 | 2.229380e-02 | 0 | 0 | 2.793326 | 19.37166 | DUSP4;HSPA6;HSPB1;FOS;HSPA2;DUSP6;RELB;TGFBR2;... |
22 | WikiPathways_2024_Human | Circadian Rhythm Genes WP3594 | 1.149407e-03 | 2.437941e-02 | 0 | 0 | 3.023350 | 20.46357 | NGFR;EGR3;ID2;LEP;KCNMA1;UBC;ID3;TOP1;LGR4;PML... |
23 | WikiPathways_2024_Human | Trans Sulfuration Pathway WP2333 | 1.180663e-03 | 2.437941e-02 | 0 | 0 | 18.885520 | 127.32010 | GOT1;CTH;GCLM |
24 | WikiPathways_2024_Human | Chromosomal And Microsatellite Instability In ... | 1.209296e-03 | 2.437941e-02 | 0 | 0 | 4.702346 | 31.58903 | CCND1;GADD45B;RAC2;PMAIP1;FOS;DDB2;TGFBR2 |
25 | WikiPathways_2024_Human | NRF2 ARE Regulation WP4357 | 1.303777e-03 | 2.527321e-02 | 0 | 0 | 9.809306 | 65.15822 | NQO1;HMOX1;SLC7A11;GCLM |
26 | WikiPathways_2024_Human | Vitamin D Receptor Pathway WP2877 | 1.425725e-03 | 2.661353e-02 | 0 | 0 | 3.120441 | 20.44849 | SLC37A2;CDKN2B;CCND1;VDR;DNER;TNFAIP3;CD14;MXD... |
27 | WikiPathways_2024_Human | Photodynamic Therapy Induced NFE2L2 NRF2 Survi... | 1.550683e-03 | 2.791230e-02 | 0 | 0 | 9.292545 | 60.11403 | NQO1;HMOX1;FOS;GCLM |
28 | WikiPathways_2024_Human | Development Of Pulmonary Dendritic Cells And M... | 2.677009e-03 | 4.435002e-02 | 0 | 0 | 13.217810 | 78.28981 | BATF3;ID2;RUNX2 |
29 | WikiPathways_2024_Human | H19 Rb E2F1 And CDK Beta Catenin In Colorectal... | 2.677009e-03 | 4.435002e-02 | 0 | 0 | 13.217810 | 78.28981 | CSRP2;CCND1;PMAIP1 |
30 | WikiPathways_2024_Human | Amino Acid Metabolism WP3925 | 2.727878e-03 | 4.435002e-02 | 0 | 0 | 4.028278 | 23.78389 | ARG2;GOT1;GPT2;CTH;ASNS;PYCR1;GCLM |
31 | WikiPathways_2024_Human | Apoptosis Modulation And Signaling WP1772 | 3.115759e-03 | 4.856736e-02 | 0 | 0 | 3.925888 | 22.65741 | TNFRSF6B;BAG3;PEA15;PMAIP1;FOS;MAP3K14;HSPA1A |
32 | WikiPathways_2024_Human | Pancreatic Cancer Subtypes WP5390 | 3.180006e-03 | 4.856736e-02 | 0 | 0 | 5.524083 | 31.76829 | SERPINB3;KRT17;ANXA10;TNS4;AREG |
33 | WikiPathways_2024_Human | Iron Sulfur Cluster Biogenesis WP5152 | 3.351052e-03 | 4.967442e-02 | 0 | 0 | 12.015570 | 68.47048 | NFS1;GLRX5;FDXR |
dropped_datafileORA_df4=filtereddatafileORA_4.drop(['Adjusted P-value','Odds Ratio','Old P-value','Gene_set','P-value','Old adjusted P-value','Combined Score'],axis=1)
droppeddatafileORAdf4=dropped_datafileORA_df4.copy()
droppeddatafileORAdf4['Genes']= droppeddatafileORAdf4['Genes'].replace({';':','},regex=True)
df4_ORApathwaytable=droppeddatafileORAdf4.copy()
df4_ORApathwaytable['Genes'] = df4_ORApathwaytable['Genes'].astype(str)
df4_ORApathwaytable['Genes'] = df4_ORApathwaytable['Genes'].str.split(',')
exploded_df4_ORApathwaytable = df4_ORApathwaytable.explode('Genes', ignore_index=True)
Section 8.5.3 For loop to get overlapping genes
In this section, the number of overlapping genes between the significant enrichment score-based Key Events and enriched pathways from ORA are calculated.
Step 55. Next, two sets are created by converting the significant KE table and ORA pathway table into dictionaries where the values of the genes are grouped together per key. This is followed by running a for loop to calculate the number of overlapping genes along with the symbols.
ORA_gene_sets4 = exploded_df4_ORApathwaytable.groupby('Term')['Genes'].apply(set).to_dict()
SignificantKE_gene_sets4 = significantKEIDgenetable4.groupby('KEID')['gene'].apply(set).to_dict()
overlapping_genes_betweenORA_and_significantKEs4 = {}
for term, ORA_genes in ORA_gene_sets4.items():
for KEID, KEID_genes in SignificantKE_gene_sets4.items():
overlap = ORA_genes.intersection(KEID_genes)
print(f"{term} x {KEID}: {len(overlap)} overlaps")
overlapping_genes_betweenORA_and_significantKEs4[(term, KEID)] = {
'overlapping genes': overlap,
'number of genes that overlap': len(overlap)
}
if overlapping_genes_betweenORA_and_significantKEs4:
print("\ntitle of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:")
for (term, KEID), result in overlapping_genes_betweenORA_and_significantKEs4.items():
print(f"Term: {term}, KEID: {KEID}, Title of overlapping gene(s): {result['overlapping genes']}, number: {result['number of genes that overlap']}")
else:
print("No overlapping genes")
Adipogenesis WP236 x https://identifiers.org/aop.events/1087: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1115: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1270: 3 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1271: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1392: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1457: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1488: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/149: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1493: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1496: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1497: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1498: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1500: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1538: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1585: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1587: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1633: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1669: 2 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1750: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1814: 3 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1815: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1820: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1896: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/1917: 1 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/195: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/2006: 2 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/2012: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/209: 3 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/244: 4 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/249: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/265: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/386: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/388: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/41: 2 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/52: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/68: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/87: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/875: 0 overlaps
Adipogenesis WP236 x https://identifiers.org/aop.events/890: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1087: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1115: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1270: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1271: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1392: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1457: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1488: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/149: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1493: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1496: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1497: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1498: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1500: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1538: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1585: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1587: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1633: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1669: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1750: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1814: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1815: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1820: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1896: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/1917: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/195: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/2006: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/2012: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/209: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/244: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/249: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/265: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/386: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/388: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/41: 1 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/52: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/68: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/87: 0 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/875: 2 overlaps
Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213 x https://identifiers.org/aop.events/890: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1087: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1115: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1270: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1271: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1392: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1457: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1488: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/149: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1493: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1496: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1497: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1498: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1500: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1538: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1585: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1587: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1633: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1669: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1750: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1814: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1815: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1820: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1896: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/1917: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/195: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/2006: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/2012: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/209: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/244: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/249: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/265: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/386: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/388: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/41: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/52: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/68: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/87: 0 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/875: 1 overlaps
Amino Acid Metabolism WP3925 x https://identifiers.org/aop.events/890: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1087: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1115: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1270: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1271: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1392: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1457: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1488: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/149: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1493: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1496: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1497: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1498: 1 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1500: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1538: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1585: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1587: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1633: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1669: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1750: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1814: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1815: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1820: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1896: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/1917: 4 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/195: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/2006: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/2012: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/209: 5 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/244: 4 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/249: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/265: 2 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/386: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/388: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/41: 4 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/52: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/68: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/87: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/875: 0 overlaps
Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113 x https://identifiers.org/aop.events/890: 2 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1087: 3 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1115: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1270: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1271: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1392: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1457: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1488: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/149: 3 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1493: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1496: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1497: 3 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1498: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1500: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1538: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1585: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1587: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1633: 3 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1669: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1750: 3 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1814: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1815: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1820: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1896: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/1917: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/195: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/2006: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/2012: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/209: 3 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/244: 2 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/249: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/265: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/386: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/388: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/41: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/52: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/68: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/87: 0 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/875: 1 overlaps
Apoptosis Modulation And Signaling WP1772 x https://identifiers.org/aop.events/890: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1087: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1115: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1270: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1271: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1392: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1457: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1488: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/149: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1493: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1496: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1497: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1498: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1500: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1538: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1585: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1587: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1633: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1669: 5 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1750: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1814: 5 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1815: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1820: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1896: 4 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/1917: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/195: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/2006: 5 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/2012: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/209: 5 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/244: 6 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/249: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/265: 3 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/386: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/388: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/41: 1 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/52: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/68: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/87: 0 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/875: 2 overlaps
Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216 x https://identifiers.org/aop.events/890: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1087: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1115: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1270: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1271: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1392: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1457: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1488: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/149: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1493: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1496: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1497: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1498: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1500: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1538: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1585: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1587: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1633: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1669: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1750: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1814: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1815: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1820: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1896: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/1917: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/195: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/2006: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/2012: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/209: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/244: 2 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/249: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/265: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/386: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/388: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/41: 1 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/52: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/68: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/87: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/875: 0 overlaps
Circadian Rhythm Genes WP3594 x https://identifiers.org/aop.events/890: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1087: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1115: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1270: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1271: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1392: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1457: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1488: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/149: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1493: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1496: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1497: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1498: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1500: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1538: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1585: 1 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1587: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1633: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1669: 7 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1750: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1814: 7 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1815: 1 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1820: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1896: 7 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/1917: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/195: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/2006: 7 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/2012: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/209: 6 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/244: 7 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/249: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/265: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/386: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/388: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/41: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/52: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/68: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/87: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/875: 0 overlaps
DNA Damage Response WP707 x https://identifiers.org/aop.events/890: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1087: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1115: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1270: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1271: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1392: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1457: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1488: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/149: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1493: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1496: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1497: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1498: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1500: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1538: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1585: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1587: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1633: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1669: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1750: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1814: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1815: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1820: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1896: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/1917: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/195: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/2006: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/2012: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/209: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/244: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/249: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/265: 1 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/386: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/388: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/41: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/52: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/68: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/87: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/875: 0 overlaps
Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892 x https://identifiers.org/aop.events/890: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1087: 2 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1115: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1270: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1271: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1392: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1457: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1488: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/149: 2 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1493: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1496: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1497: 2 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1498: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1500: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1538: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1585: 4 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1587: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1633: 2 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1669: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1750: 2 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1814: 4 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1815: 4 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1820: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1896: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/1917: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/195: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/2006: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/2012: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/209: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/244: 4 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/249: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/265: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/386: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/388: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/41: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/52: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/68: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/87: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/875: 0 overlaps
Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861 x https://identifiers.org/aop.events/890: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1087: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1115: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1270: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1271: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1392: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1457: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1488: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/149: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1493: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1496: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1497: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1498: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1500: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1538: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1585: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1587: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1633: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1669: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1750: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1814: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1815: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1820: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1896: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/1917: 3 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/195: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/2006: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/2012: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/209: 4 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/244: 3 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/249: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/265: 1 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/386: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/388: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/41: 3 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/52: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/68: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/87: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/875: 0 overlaps
Ferroptosis WP4313 x https://identifiers.org/aop.events/890: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1087: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1115: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1270: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1271: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1392: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1457: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1488: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/149: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1493: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1496: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1497: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1498: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1500: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1538: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1585: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1587: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1633: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1669: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1750: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1814: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1815: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1820: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1896: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/1917: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/195: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/2006: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/2012: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/209: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/244: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/249: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/265: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/386: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/388: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/41: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/52: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/68: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/87: 1 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/875: 0 overlaps
Glucocorticoid Receptor Pathway WP2880 x https://identifiers.org/aop.events/890: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1087: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1115: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1270: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1271: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1392: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1457: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1488: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/149: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1493: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1496: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1497: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1498: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1500: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1538: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1585: 1 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1587: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1633: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1669: 2 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1750: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1814: 2 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1815: 1 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1820: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1896: 2 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/1917: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/195: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/2006: 2 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/2012: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/209: 2 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/244: 2 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/249: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/265: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/386: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/388: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/41: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/52: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/68: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/87: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/875: 0 overlaps
H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969 x https://identifiers.org/aop.events/890: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1087: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1115: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1270: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1271: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1392: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1457: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1488: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/149: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1493: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1496: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1497: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1498: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1500: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1538: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1585: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1587: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1633: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1669: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1750: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1814: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1815: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1820: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1896: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/1917: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/195: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/2006: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/2012: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/209: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/244: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/249: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/265: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/386: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/388: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/41: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/52: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/68: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/87: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/875: 0 overlaps
Iron Sulfur Cluster Biogenesis WP5152 x https://identifiers.org/aop.events/890: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1087: 14 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1115: 1 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1270: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1271: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1392: 1 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1457: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1488: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/149: 14 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1493: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1496: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1497: 14 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1498: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1500: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1538: 1 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1585: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1587: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1633: 14 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1669: 1 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1750: 14 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1814: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1815: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1820: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1896: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/1917: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/195: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/2006: 1 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/2012: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/209: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/244: 5 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/249: 1 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/265: 3 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/386: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/388: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/41: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/52: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/68: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/87: 0 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/875: 2 overlaps
MAPK Signaling WP382 x https://identifiers.org/aop.events/890: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1087: 2 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1115: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1270: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1271: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1392: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1457: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1488: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/149: 2 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1493: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1496: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1497: 2 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1498: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1500: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1538: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1585: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1587: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1633: 2 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1669: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1750: 2 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1814: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1815: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1820: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1896: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/1917: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/195: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/2006: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/2012: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/209: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/244: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/249: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/265: 1 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/386: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/388: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/41: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/52: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/68: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/87: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/875: 0 overlaps
Macrophage Markers WP4146 x https://identifiers.org/aop.events/890: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1087: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1115: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1270: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1271: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1392: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1457: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1488: 2 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/149: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1493: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1496: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1497: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1498: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1500: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1538: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1585: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1587: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1633: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1669: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1750: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1814: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1815: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1820: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1896: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/1917: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/195: 2 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/2006: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/2012: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/209: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/244: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/249: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/265: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/386: 2 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/388: 2 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/41: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/52: 2 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/68: 5 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/87: 0 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/875: 2 overlaps
Metabolic Pathways Of Fibroblasts WP5312 x https://identifiers.org/aop.events/890: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1087: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1115: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1270: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1271: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1392: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1457: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1488: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/149: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1493: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1496: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1497: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1498: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1500: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1538: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1585: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1587: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1633: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1669: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1750: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1814: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1815: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1820: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1896: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/1917: 4 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/195: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/2006: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/2012: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/209: 4 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/244: 4 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/249: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/265: 2 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/386: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/388: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/41: 4 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/52: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/68: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/87: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/875: 0 overlaps
NRF2 ARE Regulation WP4357 x https://identifiers.org/aop.events/890: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1087: 3 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1115: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1270: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1271: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1392: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1457: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1488: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/149: 3 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1493: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1496: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1497: 3 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1498: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1500: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1538: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1585: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1587: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1633: 3 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1669: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1750: 3 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1814: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1815: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1820: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1896: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/1917: 13 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/195: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/2006: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/2012: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/209: 13 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/244: 13 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/249: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/265: 3 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/386: 2 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/388: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/41: 13 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/52: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/68: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/87: 0 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/875: 1 overlaps
NRF2 Pathway WP2884 x https://identifiers.org/aop.events/890: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1087: 4 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1115: 3 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1270: 3 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1271: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1392: 3 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1457: 0 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1488: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/149: 4 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1493: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1496: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1497: 4 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1498: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1500: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1538: 3 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1585: 0 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1587: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1633: 4 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1669: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1750: 4 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1814: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1815: 0 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1820: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1896: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/1917: 13 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/195: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/2006: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/2012: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/209: 16 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/244: 15 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/249: 3 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/265: 4 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/386: 2 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/388: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/41: 14 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/52: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/68: 0 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/87: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/875: 1 overlaps
Nuclear Receptors Meta Pathway WP2882 x https://identifiers.org/aop.events/890: 3 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1087: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1115: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1270: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1271: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1392: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1457: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1488: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/149: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1493: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1496: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1497: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1498: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1500: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1538: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1585: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1587: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1633: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1669: 4 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1750: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1814: 4 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1815: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1820: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1896: 5 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/1917: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/195: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/2006: 4 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/2012: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/209: 11 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/244: 5 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/249: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/265: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/386: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/388: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/41: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/52: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/68: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/87: 1 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/875: 0 overlaps
P53 Transcriptional Gene Network WP4963 x https://identifiers.org/aop.events/890: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1087: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1115: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1270: 7 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1271: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1392: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1457: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1488: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/149: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1493: 1 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1496: 1 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1497: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1498: 1 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1500: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1538: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1585: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1587: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1633: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1669: 1 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1750: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1814: 1 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1815: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1820: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1896: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/1917: 2 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/195: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/2006: 1 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/2012: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/209: 7 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/244: 3 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/249: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/265: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/386: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/388: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/41: 2 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/52: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/68: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/87: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/875: 0 overlaps
PPAR Signaling WP3942 x https://identifiers.org/aop.events/890: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1087: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1115: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1270: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1271: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1392: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1457: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1488: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/149: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1493: 1 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1496: 1 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1497: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1498: 1 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1500: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1538: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1585: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1587: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1633: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1669: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1750: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1814: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1815: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1820: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1896: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/1917: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/195: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/2006: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/2012: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/209: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/244: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/249: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/265: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/386: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/388: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/41: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/52: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/68: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/87: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/875: 0 overlaps
Pancreatic Cancer Subtypes WP5390 x https://identifiers.org/aop.events/890: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1087: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1115: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1270: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1271: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1392: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1457: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1488: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/149: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1493: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1496: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1497: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1498: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1500: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1538: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1585: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1587: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1633: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1669: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1750: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1814: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1815: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1820: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1896: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/1917: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/195: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/2006: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/2012: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/209: 4 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/244: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/249: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/265: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/386: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/388: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/41: 3 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/52: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/68: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/87: 0 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/875: 1 overlaps
Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612 x https://identifiers.org/aop.events/890: 3 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1087: 2 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1115: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1270: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1271: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1392: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1457: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1488: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/149: 2 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1493: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1496: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1497: 2 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1498: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1500: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1538: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1585: 4 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1587: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1633: 2 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1669: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1750: 2 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1814: 4 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1815: 4 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1820: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1896: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/1917: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/195: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/2006: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/2012: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/209: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/244: 4 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/249: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/265: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/386: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/388: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/41: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/52: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/68: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/87: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/875: 0 overlaps
Photodynamic Therapy Induced Unfolded Protein Response WP3613 x https://identifiers.org/aop.events/890: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1087: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1115: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1270: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1271: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1392: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1457: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1488: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/149: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1493: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1496: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1497: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1498: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1500: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1538: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1585: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1587: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1633: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1669: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1750: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1814: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1815: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1820: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1896: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/1917: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/195: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/2006: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/2012: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/209: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/244: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/249: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/265: 9 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/386: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/388: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/41: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/52: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/68: 0 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/87: 1 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/875: 3 overlaps
TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816 x https://identifiers.org/aop.events/890: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1087: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1115: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1270: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1271: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1392: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1457: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1488: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/149: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1493: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1496: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1497: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1498: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1500: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1538: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1585: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1587: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1633: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1669: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1750: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1814: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1815: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1820: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1896: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/1917: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/195: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/2006: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/2012: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/209: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/244: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/249: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/265: 9 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/386: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/388: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/41: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/52: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/68: 0 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/87: 1 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/875: 3 overlaps
TGF Beta Receptor Signaling WP560 x https://identifiers.org/aop.events/890: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1087: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1115: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1270: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1271: 6 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1392: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1457: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1488: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/149: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1493: 7 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1496: 7 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1497: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1498: 7 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1500: 6 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1538: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1585: 0 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1587: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1633: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1669: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1750: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1814: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1815: 0 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1820: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1896: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/1917: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/195: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/2006: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/2012: 6 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/209: 7 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/244: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/249: 2 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/265: 7 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/386: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/388: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/41: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/52: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/68: 0 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/87: 1 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/875: 3 overlaps
TGF Beta Signaling Pathway WP366 x https://identifiers.org/aop.events/890: 2 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1087: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1115: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1270: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1271: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1392: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1457: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1488: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/149: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1493: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1496: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1497: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1498: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1500: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1538: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1585: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1587: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1633: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1669: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1750: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1814: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1815: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1820: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1896: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/1917: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/195: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/2006: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/2012: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/209: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/244: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/249: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/265: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/386: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/388: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/41: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/52: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/68: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/87: 0 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/875: 1 overlaps
Trans Sulfuration Pathway WP2333 x https://identifiers.org/aop.events/890: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1087: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1115: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1270: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1271: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1392: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1457: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1488: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/149: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1493: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1496: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1497: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1498: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1500: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1538: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1585: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1587: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1633: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1669: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1750: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1814: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1815: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1820: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1896: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/1917: 4 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/195: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/2006: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/2012: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/209: 4 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/244: 4 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/249: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/265: 2 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/386: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/388: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/41: 4 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/52: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/68: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/87: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/875: 0 overlaps
Transcriptional Activation By NRF2 In Response To Phytochemicals WP3 x https://identifiers.org/aop.events/890: 2 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1087: 2 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1115: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1270: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1271: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1392: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1457: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1488: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/149: 2 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1493: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1496: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1497: 2 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1498: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1500: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1538: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1585: 5 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1587: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1633: 2 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1669: 1 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1750: 2 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1814: 5 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1815: 5 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1820: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1896: 1 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/1917: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/195: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/2006: 1 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/2012: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/209: 1 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/244: 5 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/249: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/265: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/386: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/388: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/41: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/52: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/68: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/87: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/875: 0 overlaps
Unfolded Protein Response WP4925 x https://identifiers.org/aop.events/890: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1087: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1115: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1270: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1271: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1392: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1457: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1488: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/149: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1493: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1496: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1497: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1498: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1500: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1538: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1585: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1587: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1633: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1669: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1750: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1814: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1815: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1820: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1896: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/1917: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/195: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/2006: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/2012: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/209: 3 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/244: 2 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/249: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/265: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/386: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/388: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/41: 1 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/52: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/68: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/87: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/875: 0 overlaps
Vitamin D Receptor Pathway WP2877 x https://identifiers.org/aop.events/890: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1087: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1115: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1270: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1271: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1392: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1457: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1488: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/149: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1493: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1496: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1497: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1498: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1500: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1538: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1585: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1587: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1633: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1669: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1750: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1814: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1815: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1820: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1896: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/1917: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/195: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/2006: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/2012: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/209: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/244: 2 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/249: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/265: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/386: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/388: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/41: 1 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/52: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/68: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/87: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/875: 0 overlaps
mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953 x https://identifiers.org/aop.events/890: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1087: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1115: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1270: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1271: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1392: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1457: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1488: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/149: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1493: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1496: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1497: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1498: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1500: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1538: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1585: 1 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1587: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1633: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1669: 7 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1750: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1814: 7 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1815: 1 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1820: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1896: 7 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/1917: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/195: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/2006: 7 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/2012: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/209: 6 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/244: 7 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/249: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/265: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/386: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/388: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/41: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/52: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/68: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/87: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/875: 0 overlaps
miRNA Regulation Of DNA Damage Response WP1530 x https://identifiers.org/aop.events/890: 0 overlaps
title of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'SCD', 'PPARD', 'PCK2'}, number: 3
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'GADD45B', 'PCK2'}, number: 2
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'DDIT3', 'GADD45B', 'PCK2'}, number: 3
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'DDIT3'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'GADD45B'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'PPARD'}, number: 1
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'GADD45B', 'PCK2'}, number: 2
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SCD', 'PPARD', 'PCK2'}, number: 3
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'DDIT3', 'PPARD', 'GADD45B', 'PCK2'}, number: 4
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'LEP', 'PPARD'}, number: 2
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Adipogenesis WP236, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): {'PYCR1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Amino Acid Metabolism WP3925, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SLC7A11', 'GCLM', 'MMP1', 'NQO1', 'HMOX1'}, number: 5
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'MAP3K14', 'HSPA1A', 'FOS'}, number: 3
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'MAP3K14', 'HSPA1A', 'FOS'}, number: 3
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'MAP3K14', 'HSPA1A', 'FOS'}, number: 3
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'MAP3K14', 'HSPA1A', 'FOS'}, number: 3
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'MAP3K14', 'HSPA1A', 'FOS'}, number: 3
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HSPA1A'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HSPA1A', 'PMAIP1', 'FOS'}, number: 3
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HSPA1A', 'PMAIP1'}, number: 2
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HSPA1A'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Apoptosis Modulation And Signaling WP1772, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'RAC2', 'GADD45B', 'CCND1', 'DDB2', 'PMAIP1'}, number: 5
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'RAC2', 'GADD45B', 'CCND1', 'DDB2', 'PMAIP1'}, number: 5
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'DDB2', 'PMAIP1', 'GADD45B', 'CCND1'}, number: 4
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'RAC2', 'GADD45B', 'CCND1', 'DDB2', 'PMAIP1'}, number: 5
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'TGFBR2', 'CCND1', 'DDB2', 'PMAIP1', 'FOS'}, number: 5
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'RAC2', 'GADD45B', 'TGFBR2', 'CCND1', 'DDB2', 'PMAIP1'}, number: 6
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'RELB', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'RELB', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'RELB', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'RELB', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'PML'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'RELB', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'PML', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'PML'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'PML'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'PML'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'PML', 'ATF4'}, number: 2
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'NGFR'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'LEP'}, number: 1
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Circadian Rhythm Genes WP3594, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 6
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: DNA Damage Response WP707, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'HSPB1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'HSPB1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'HSPB1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'HSPB1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'HSPB1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HMOX1', 'SLC7A11', 'GCLM'}, number: 3
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SAT1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HMOX1', 'SLC7A11', 'GCLM'}, number: 3
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HMOX1', 'SLC7A11', 'GCLM'}, number: 3
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Ferroptosis WP4313, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'HMOX1'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'GADD45B'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'GADD45B'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'GADD45B'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'GADD45B'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'GADD45B'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Glucocorticoid Receptor Pathway WP2880, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'PMAIP1', 'CCND1'}, number: 2
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'PMAIP1', 'CCND1'}, number: 2
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'PMAIP1', 'CCND1'}, number: 2
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'PMAIP1', 'CCND1'}, number: 2
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'PMAIP1', 'CCND1'}, number: 2
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'PMAIP1', 'CCND1'}, number: 2
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Iron Sulfur Cluster Biogenesis WP5152, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'HSPA6', 'RELB', 'HSPA1A', 'DUSP6', 'RAC2', 'CD14', 'DDIT3', 'ATF4', 'TGFBR2', 'MAP3K14', 'HSPA2', 'DUSP4', 'HSPB1', 'FOS'}, number: 14
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'HSPA6', 'RELB', 'HSPA1A', 'DUSP6', 'RAC2', 'CD14', 'DDIT3', 'ATF4', 'TGFBR2', 'MAP3K14', 'HSPA2', 'DUSP4', 'HSPB1', 'FOS'}, number: 14
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'HSPA6', 'RELB', 'HSPA1A', 'DUSP6', 'RAC2', 'CD14', 'DDIT3', 'ATF4', 'TGFBR2', 'MAP3K14', 'HSPA2', 'DUSP4', 'HSPB1', 'FOS'}, number: 14
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'HSPA6', 'RELB', 'HSPA1A', 'DUSP6', 'RAC2', 'CD14', 'DDIT3', 'ATF4', 'TGFBR2', 'MAP3K14', 'HSPA2', 'DUSP4', 'HSPB1', 'FOS'}, number: 14
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'HSPA6', 'RELB', 'HSPA1A', 'DUSP6', 'RAC2', 'CD14', 'DDIT3', 'ATF4', 'TGFBR2', 'MAP3K14', 'HSPA2', 'DUSP4', 'HSPB1', 'FOS'}, number: 14
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'ATF4', 'DDIT3', 'RAC2'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2', 'FOS'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'HSPA1A', 'RAC2', 'ATF4', 'DDIT3', 'TGFBR2'}, number: 5
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'RAC2', 'TGFBR2', 'FOS'}, number: 3
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'TGFBR2', 'FOS'}, number: 2
Term: MAPK Signaling WP382, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'RAC2', 'CD14'}, number: 2
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'RAC2', 'CD14'}, number: 2
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'RAC2', 'CD14'}, number: 2
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'RAC2', 'CD14'}, number: 2
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'RAC2', 'CD14'}, number: 2
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'RAC2'}, number: 1
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Macrophage Markers WP4146, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): {'PSAT1', 'PHGDH', 'PYCR1', 'SERPINH1', 'UGDH'}, number: 5
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'PSAT1', 'PHGDH'}, number: 2
Term: Metabolic Pathways Of Fibroblasts WP5312, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: NRF2 ARE Regulation WP4357, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 3
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'PPARD', 'ME1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 3
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 3
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 3
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 3
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'DNAJB1', 'HSPA1A', 'SLC7A11', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'TGFBR2', 'SQSTM1', 'NQO1', 'HMOX1', 'MAFF', 'ME1'}, number: 13
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'DNAJB1', 'HSPA1A', 'SLC7A11', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'TGFBR2', 'SQSTM1', 'NQO1', 'HMOX1', 'MAFF', 'ME1'}, number: 13
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'DNAJB1', 'HSPA1A', 'SLC7A11', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'TGFBR2', 'SQSTM1', 'NQO1', 'HMOX1', 'MAFF', 'ME1'}, number: 13
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'TGFBR2'}, number: 3
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'TGFBR2', 'SQSTM1'}, number: 2
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'DNAJB1', 'HSPA1A', 'SLC7A11', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'TGFBR2', 'SQSTM1', 'NQO1', 'HMOX1', 'MAFF', 'ME1'}, number: 13
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: NRF2 Pathway WP2884, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'IL11', 'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 4
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'JUNB'}, number: 3
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'SCD', 'PPARD', 'ME1'}, number: 3
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'JUNB'}, number: 3
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'IL11', 'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 4
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'IL11', 'TGFBR2'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'IL11', 'TGFBR2'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'IL11', 'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 4
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'IL11', 'TGFBR2'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'IL11', 'TGFBR2'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'JUNB'}, number: 3
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'IL11', 'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 4
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'GADD45B', 'CCND1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'IL11', 'HSPA1A', 'TGFBR2', 'SQSTM1'}, number: 4
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'GADD45B', 'CCND1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'GADD45B', 'CCND1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SQSTM1', 'DNAJB1', 'SLC7A11', 'HSPA1A', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'MAFF', 'TGFBR2', 'NQO1', 'HMOX1', 'ME1'}, number: 13
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'GADD45B', 'CCND1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'IL11', 'TGFBR2'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SQSTM1', 'DNAJB1', 'SLC7A11', 'HSPA1A', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'SCD', 'MAFF', 'TGFBR2', 'NQO1', 'HMOX1', 'CCND1', 'JUNB', 'ME1'}, number: 16
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SQSTM1', 'DNAJB1', 'SLC7A11', 'HSPA1A', 'HBEGF', 'GADD45B', 'PRDX6', 'PPARD', 'GCLM', 'MAFF', 'TGFBR2', 'NQO1', 'HMOX1', 'CCND1', 'ME1'}, number: 15
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'JUNB'}, number: 3
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'TGFBR2', 'JUNB'}, number: 4
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'TGFBR2', 'SQSTM1'}, number: 2
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SQSTM1', 'DNAJB1', 'SLC7A11', 'HSPA1A', 'HBEGF', 'PRDX6', 'PPARD', 'GCLM', 'MAFF', 'TGFBR2', 'NQO1', 'HMOX1', 'IP6K3', 'ME1'}, number: 14
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): {'IL11'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: Nuclear Receptors Meta Pathway WP2882, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'JUNB'}, number: 3
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'DDB2', 'PML', 'PMAIP1', 'SESN1'}, number: 4
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'DDB2', 'PML', 'PMAIP1', 'SESN1'}, number: 4
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'PCNA', 'PML', 'SESN1', 'DDB2', 'PMAIP1'}, number: 5
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'DDB2', 'PML', 'PMAIP1', 'SESN1'}, number: 4
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'ADORA2B', 'SAT1', 'PCNA', 'SLC7A11', 'PML', 'SESN1', 'THBS1', 'DDB2', 'PMAIP1', 'SESN2', 'ULBP2'}, number: 11
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SLC7A11', 'PML', 'SESN1', 'DDB2', 'PMAIP1'}, number: 5
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: P53 Transcriptional Gene Network WP4963, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'FABP5', 'PPARD', 'PCK2', 'ACOX2', 'MMP1', 'SCD', 'ME1'}, number: 7
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'PCK2'}, number: 1
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'PCK2'}, number: 1
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'PPARD', 'ME1'}, number: 2
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'PCK2'}, number: 1
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'FABP5', 'PPARD', 'PCK2', 'ACOX2', 'MMP1', 'SCD', 'ME1'}, number: 7
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'ME1', 'PPARD', 'PCK2'}, number: 3
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'PPARD', 'ME1'}, number: 2
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: PPAR Signaling WP3942, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'AREG'}, number: 1
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'AREG'}, number: 1
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'AREG'}, number: 1
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Pancreatic Cancer Subtypes WP5390, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'FOS'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'FOS'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'FOS'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'GCLM'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'GCLM', 'FOS'}, number: 4
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'GCLM'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'FOS'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'FOS'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'GCLM'}, number: 3
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'FOS'}, number: 1
Term: Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'FOS'}, number: 3
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'XBP1', 'ATF4', 'DDIT3', 'PPP1R15A'}, number: 4
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Photodynamic Therapy Induced Unfolded Protein Response WP3613, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'RUNX2'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'BAMBI', 'LTBP1', 'FST', 'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 9
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Receptor Signaling WP560, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'FOS'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'JUNB', 'FOS'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'MMP1'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): {'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 6
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'JUNB', 'FOS'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): {'TNC', 'RUNX2'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): {'MMP1', 'RUNX2', 'SKI', 'TGFBR2', 'THBS1', 'SMAD7', 'FOS'}, number: 7
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): {'MMP1', 'RUNX2', 'SKI', 'TGFBR2', 'THBS1', 'SMAD7', 'FOS'}, number: 7
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): {'MMP1', 'RUNX2', 'SKI', 'TGFBR2', 'THBS1', 'SMAD7', 'FOS'}, number: 7
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): {'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 6
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'JUNB', 'FOS'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'PML', 'CCND1'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'FOS', 'THBS1', 'TGFBR2'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'PML', 'CCND1'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'PML', 'CCND1'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'PML', 'CCND1'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): {'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'FOS'}, number: 6
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'MMP1', 'PML', 'TGFBR2', 'CCND1', 'THBS1', 'JUNB', 'FOS'}, number: 7
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'PML', 'TGFBR2', 'CCND1'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'JUNB', 'FOS'}, number: 2
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'RUNX2', 'SKI', 'THBS1', 'TGFBR2', 'SMAD7', 'JUNB', 'FOS'}, number: 7
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'TGFBR2'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): {'THBS1'}, number: 1
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'SMAD7', 'TGFBR2', 'FOS'}, number: 3
Term: TGF Beta Signaling Pathway WP366, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'JUNB', 'FOS'}, number: 2
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'GCLM'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): {'GOT1'}, number: 1
Term: Trans Sulfuration Pathway WP2333, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'NQO1', 'HMOX1', 'SLC7A11', 'GCLM'}, number: 4
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Transcriptional Activation By NRF2 In Response To Phytochemicals WP3, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'NQO1', 'HMOX1'}, number: 2
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'XBP1', 'PPP1R15A', 'ATF4', 'DDIT3', 'PMAIP1'}, number: 5
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'ATF4', 'DDIT3'}, number: 2
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'XBP1', 'PPP1R15A', 'ATF4', 'DDIT3', 'PMAIP1'}, number: 5
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'XBP1', 'PPP1R15A', 'ATF4', 'DDIT3', 'PMAIP1'}, number: 5
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'XBP1', 'PPP1R15A', 'ATF4', 'DDIT3', 'PMAIP1'}, number: 5
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Unfolded Protein Response WP4925, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'CD14'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): {'JUNB'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): {'PPARD'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): {'JUNB'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'CD14'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'CD14'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): {'JUNB'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'CD14'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'CCND1'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'CD14'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'CCND1'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'CCND1'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'PPARD'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'CCND1'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'PPARD', 'JUNB', 'CCND1'}, number: 3
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'PPARD', 'CCND1'}, number: 2
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): {'JUNB'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): {'JUNB'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'PPARD'}, number: 1
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: Vitamin D Receptor Pathway WP2877, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): {'JUNB'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'ATF4'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'SLC7A11', 'ATF4'}, number: 2
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): {'SLC7A11'}, number: 1
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1087, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1115, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1270, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1271, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1392, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1457, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1488, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/149, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1493, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1496, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1497, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1498, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1500, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1538, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1585, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1587, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1633, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1669, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1750, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1814, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'PMAIP1'}, number: 1
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1820, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1896, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/1917, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/195, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/2006, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/2012, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/209, Title of overlapping gene(s): {'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 6
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/244, Title of overlapping gene(s): {'GADD45B', 'PML', 'RAD52', 'SESN1', 'CCND1', 'DDB2', 'PMAIP1'}, number: 7
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/249, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/265, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/386, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/388, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/41, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/52, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/68, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/87, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/875, Title of overlapping gene(s): set(), number: 0
Term: miRNA Regulation Of DNA Damage Response WP1530, KEID: https://identifiers.org/aop.events/890, Title of overlapping gene(s): set(), number: 0
Section 8.5.4 Tabulation gene overlap
In this section, a table is created that contains the number of overlapping genes and number of total genes in preparation for section 8.5.5.
final_geneoverlaptable_C4=pd.DataFrame.from_dict(overlapping_genes_betweenORA_and_significantKEs4,orient='index')
Section 8.5.5 Percent overlap calculation
In this section, the percent overlap for the genesets are calculated.
Step 56. Lastly, the percent overlap is calculated and add the result as a column to the dataframe. This is first done by running a for loop to calculate the total number of genes belonging to the enriched pathways of ORA.
variable_count4= {}
for index, row in exploded_df4_ORApathwaytable.iterrows():
unique_KE = row['Term']
gene_expression_value = row['Genes']
if unique_KE not in variable_count4:
variable_count4[unique_KE] = 1
else:
variable_count4[unique_KE] += 1
print("The total number of genes: ")
print(variable_count4)
The total number of genes:
{'Nuclear Receptors Meta Pathway WP2882': 28, 'Photodynamic Therapy Induced Unfolded Protein Response WP3613': 8, 'TGF Beta Signaling Pathway WP366': 15, 'P53 Transcriptional Gene Network WP4963': 11, 'TGF Beta Receptor Signaling WP560': 9, 'TGF Beta Receptor Signaling In Skeletal Dysplasias WP4816': 9, 'Endoplasmic Reticulum Stress Response In Coronavirus Infection WP4861': 8, 'NRF2 Pathway WP2884': 13, 'Macrophage Markers WP4146': 4, 'Unfolded Protein Response WP4925': 5, 'Transcriptional Activation By NRF2 In Response To Phytochemicals WP3': 4, 'Antiviral And Anti-Inflam Effects Of Nrf2 On SARS CoV 2 Pathway WP5113': 5, 'mRNA Protein And Metabolite Inducation Pathway By Cyclosporin A WP3953': 3, 'Amino Acid Metabolism In Triple Negative Breast Cancer Cells WP5213': 3, 'Metabolic Pathways Of Fibroblasts WP5312': 5, 'Ferroptosis WP4313': 7, 'miRNA Regulation Of DNA Damage Response WP1530': 7, 'DNA Damage Response WP707': 7, 'Adipogenesis WP236': 10, 'Glucocorticoid Receptor Pathway WP2880': 7, 'PPAR Signaling WP3942': 7, 'MAPK Signaling WP382': 14, 'Circadian Rhythm Genes WP3594': 12, 'Trans Sulfuration Pathway WP2333': 3, 'Chromosomal And Microsatellite Instability In Colorectal Cancer WP4216': 7, 'NRF2 ARE Regulation WP4357': 4, 'Vitamin D Receptor Pathway WP2877': 11, 'Photodynamic Therapy Induced NFE2L2 NRF2 Survival Signaling WP3612': 4, 'Development Of Pulmonary Dendritic Cells And Macrophage Subsets WP3892': 3, 'H19 Rb E2F1 And CDK Beta Catenin In Colorectal Cancer WP3969': 3, 'Amino Acid Metabolism WP3925': 7, 'Apoptosis Modulation And Signaling WP1772': 7, 'Pancreatic Cancer Subtypes WP5390': 5, 'Iron Sulfur Cluster Biogenesis WP5152': 3}
Step 57. The result is converted into a dataframe and added to the final dataframe. This is followed by some data manipulation prior to calculation of gene set overlap.
variable_count_df4=pd.DataFrame.from_dict(variable_count4,orient='index')
reset_variable_count_df4 = variable_count_df4.reset_index()
reset_variable_count_df4.columns = ['Term', 'Total number of genes']
Genesetoverlaptable_C4=final_geneoverlaptable_C4.reset_index(level=[1])
Genesetoverlaptable_C4.reset_index(inplace=True)
Genesetoverlaptable_C4.columns= ['Term','KEID','overlapping genes','number of genes that overlap']
tabulation_C4=pd.merge(reset_variable_count_df4,Genesetoverlaptable_C4, on='Term')
def calculate_Genesetoverlap_Score(row):
return f"{(row['number of genes that overlap']/row['Total number of genes'])*100}"
tabulation_C4.loc[:,'Percent geneset overlap']= tabulation_C4.apply(calculate_Genesetoverlap_Score, axis=1)
tabulation_C4
Term | Total number of genes | KEID | overlapping genes | number of genes that overlap | Percent geneset overlap | |
---|---|---|---|---|---|---|
0 | Nuclear Receptors Meta Pathway WP2882 | 28 | https://identifiers.org/aop.events/1087 | {IL11, HSPA1A, TGFBR2, SQSTM1} | 4 | 14.285714285714285 |
1 | Nuclear Receptors Meta Pathway WP2882 | 28 | https://identifiers.org/aop.events/1115 | {NQO1, HMOX1, JUNB} | 3 | 10.714285714285714 |
2 | Nuclear Receptors Meta Pathway WP2882 | 28 | https://identifiers.org/aop.events/1270 | {SCD, PPARD, ME1} | 3 | 10.714285714285714 |
3 | Nuclear Receptors Meta Pathway WP2882 | 28 | https://identifiers.org/aop.events/1271 | {TGFBR2} | 1 | 3.571428571428571 |
4 | Nuclear Receptors Meta Pathway WP2882 | 28 | https://identifiers.org/aop.events/1392 | {NQO1, HMOX1, JUNB} | 3 | 10.714285714285714 |
... | ... | ... | ... | ... | ... | ... |
1321 | Iron Sulfur Cluster Biogenesis WP5152 | 3 | https://identifiers.org/aop.events/52 | {} | 0 | 0.0 |
1322 | Iron Sulfur Cluster Biogenesis WP5152 | 3 | https://identifiers.org/aop.events/68 | {} | 0 | 0.0 |
1323 | Iron Sulfur Cluster Biogenesis WP5152 | 3 | https://identifiers.org/aop.events/87 | {} | 0 | 0.0 |
1324 | Iron Sulfur Cluster Biogenesis WP5152 | 3 | https://identifiers.org/aop.events/875 | {} | 0 | 0.0 |
1325 | Iron Sulfur Cluster Biogenesis WP5152 | 3 | https://identifiers.org/aop.events/890 | {} | 0 | 0.0 |
1326 rows × 6 columns
Section 9. Comparison 5: Maleic anhydride timepoint 2
Section 9.1 Calculation of n variable
In this section, variable n will be calculated for the comparison 6.
Step 58. The table containing the differential expressed genes for comparison 6 to control is loaded with the filter for significance.
Comparison6_DEG= pd.read_csv("C:/Users/shaki/Downloads/DEG tables-all expressed genes/de_genes_MA.24h.tsv",sep='\t',dtype={'GENE':'string'})
The_comparison6_DEG=Comparison6_DEG.dropna(subset=['GENE_SYMBOL'])
The_Comparison6_DEG=The_comparison6_DEG.drop_duplicates(subset=['GENE'])
Comparison_6_DEG= The_Comparison6_DEG[The_Comparison6_DEG['adj.P.Val'] < 0.05]
The_comparison_6_DEG=Comparison_6_DEG.copy()
Comparison6=The_comparison_6_DEG.rename(columns={'GENE':'GENEID'})
Comparison6['GENEID'] = Comparison6['GENEID'].astype(str)
Comparison_6=Comparison6.drop(columns=['SPOT_ID','COL','ROW','NAME','ACCESSION_STRING','CHROMOSOMAL_LOCATION','CYTOBAND','ORDER','ENSEMBL_ID','SPOT_ID.1','UNIGENE_ID','TIGR_ID','GO_ID','DESCRIPTION','SEQUENCE','CONTROL_TYPE','REFSEQ','GB_ACC'])
Comparison_6
ID | GENEID | GENE_SYMBOL | GENE_NAME | logFC | AveExpr | t | P.Value | adj.P.Val | B | |
---|---|---|---|---|---|---|---|---|---|---|
0 | 28741 | 85236 | HIST1H2BK | histone cluster 1, H2bk | 0.848198 | 0.091113 | 15.764949 | 1.490379e-23 | 5.450995e-19 | 42.027883 |
1 | 21386 | 1543 | CYP1A1 | cytochrome P450, family 1, subfamily A, polype... | 0.821543 | 0.184573 | 15.613779 | 2.421857e-23 | 5.450995e-19 | 41.618011 |
2 | 16486 | 29958 | DMGDH | dimethylglycine dehydrogenase | 0.876482 | 0.050920 | 14.794873 | 3.529727e-22 | 5.296355e-18 | 39.338343 |
4 | 16942 | 219854 | TMEM218 | transmembrane protein 218 | -0.455706 | -0.067257 | -12.524192 | 9.277620e-19 | 8.352641e-15 | 32.479715 |
5 | 25809 | 138050 | HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | -0.471999 | -0.082378 | -12.106840 | 4.236592e-18 | 3.178503e-14 | 31.132408 |
... | ... | ... | ... | ... | ... | ... | ... | ... | ... | ... |
4423 | 15620 | 144501 | KRT80 | keratin 80 | 0.301665 | 0.012832 | 2.916673 | 4.895606e-03 | 4.981367e-02 | -0.681984 |
4424 | 26372 | 7145 | TNS1 | tensin 1 | -0.312052 | -0.254361 | -2.916410 | 4.899232e-03 | 4.983931e-02 | -0.682639 |
4425 | 7319 | 57335 | ZNF286A | zinc finger protein 286A | -0.138629 | 0.008597 | -2.916092 | 4.903625e-03 | 4.987272e-02 | -0.683433 |
4427 | 40411 | 58489 | FAM108C1 | family with sequence similarity 108, member C1 | -0.200178 | 0.007205 | -2.915475 | 4.912166e-03 | 4.993703e-02 | -0.684974 |
4428 | 33634 | 7076 | TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.221966 | 0.073864 | 2.915367 | 4.913662e-03 | 4.994095e-02 | -0.685243 |
3036 rows × 10 columns
Step 59. Here, the results of the DEG table are integrated into the mergeddataframe dataframe. This is followed by adjustment of the dataframe columns to remove non-relevant columns.
merged_dataframe_DEG_C6= pd.merge(mergeddataframe,Comparison_6, on='GENEID')
Step 60. Lastly, the following for loop for the key events is run to retrieve the n variable. It is comparable to the for loop of N, but adds a condition to check for significance of genes by p adjusted value being smaller than 0.05.
variable_n_dictionary_count6= {}
for index, row in merged_dataframe_DEG_C6.iterrows():
unique_KE = row['KEID']
gene_expression_value = row['adj.P.Val']
if gene_expression_value < 0.05:
if unique_KE not in variable_n_dictionary_count6:
variable_n_dictionary_count6[unique_KE] = 1
else:
variable_n_dictionary_count6[unique_KE] += 1
print("The total number of significant genes: ")
The total number of significant genes:
{'https://identifiers.org/aop.events/486': 15, 'https://identifiers.org/aop.events/875': 15, 'https://identifiers.org/aop.events/2007': 17, 'https://identifiers.org/aop.events/1495': 29, 'https://identifiers.org/aop.events/105': 31, 'https://identifiers.org/aop.events/1816': 31, 'https://identifiers.org/aop.events/1668 ': 17, 'https://identifiers.org/aop.events/244 ': 43, 'https://identifiers.org/aop.events/1739': 2, 'https://identifiers.org/aop.events/1814 ': 31, 'https://identifiers.org/aop.events/888': 8, 'https://identifiers.org/aop.events/1574': 1, 'https://identifiers.org/aop.events/41': 26, 'https://identifiers.org/aop.events/1270': 14, 'https://identifiers.org/aop.events/1086': 16, 'https://identifiers.org/aop.events/1487 ': 3, 'https://identifiers.org/aop.events/1539': 20, 'https://identifiers.org/aop.events/201': 3, 'https://identifiers.org/aop.events/457': 106, 'https://identifiers.org/aop.events/55': 32, 'https://identifiers.org/aop.events/188': 3, 'https://identifiers.org/aop.events/618': 21, 'https://identifiers.org/aop.events/389': 3, 'https://identifiers.org/aop.events/177': 93, 'https://identifiers.org/aop.events/2013': 12, 'https://identifiers.org/aop.events/2006': 23, 'https://identifiers.org/aop.events/1497': 56, 'https://identifiers.org/aop.events/870': 2, 'https://identifiers.org/aop.events/1669': 40, 'https://identifiers.org/aop.events/1115': 7, 'https://identifiers.org/aop.events/202': 18, 'https://identifiers.org/aop.events/1917': 12, 'https://identifiers.org/aop.events/1633': 112, 'https://identifiers.org/aop.events/1392': 21, 'https://identifiers.org/aop.events/1815': 14, 'https://identifiers.org/aop.events/386': 39, 'https://identifiers.org/aop.events/1582': 4, 'https://identifiers.org/aop.events/1896': 43, 'https://identifiers.org/aop.events/1172': 2, 'https://identifiers.org/aop.events/1496': 49, 'https://identifiers.org/aop.events/68': 16, 'https://identifiers.org/aop.events/1493': 98, 'https://identifiers.org/aop.events/265': 33, 'https://identifiers.org/aop.events/1817': 38, 'https://identifiers.org/aop.events/1819': 6, 'https://identifiers.org/aop.events/1750': 56, 'https://identifiers.org/aop.events/1901': 2, 'https://identifiers.org/aop.events/1848': 22, 'https://identifiers.org/aop.events/1847': 1, 'https://identifiers.org/aop.events/1365': 38, 'https://identifiers.org/aop.events/890': 7, 'https://identifiers.org/aop.events/1587': 11, 'https://identifiers.org/aop.events/1457': 3, 'https://identifiers.org/aop.events/1586': 6, 'https://identifiers.org/aop.events/149': 112, 'https://identifiers.org/aop.events/1575': 38, 'https://identifiers.org/aop.events/1579': 40, 'https://identifiers.org/aop.events/87': 22, 'https://identifiers.org/aop.events/249': 7, 'https://identifiers.org/aop.events/288': 7, 'https://identifiers.org/aop.events/209': 102, 'https://identifiers.org/aop.events/1498': 29, 'https://identifiers.org/aop.events/1499': 5, 'https://identifiers.org/aop.events/1500': 31, 'https://identifiers.org/aop.events/1488': 15, 'https://identifiers.org/aop.events/1494': 14, 'https://identifiers.org/aop.events/52': 21, 'https://identifiers.org/aop.events/381': 23, 'https://identifiers.org/aop.events/484': 109, 'https://identifiers.org/aop.events/388': 15, 'https://identifiers.org/aop.events/1262': 38, 'https://identifiers.org/aop.events/1945': 160, 'https://identifiers.org/aop.events/2009': 14, 'https://identifiers.org/aop.events/2012': 31, 'https://identifiers.org/aop.events/1770': 12, 'https://identifiers.org/aop.events/1818': 31, 'https://identifiers.org/aop.events/1738': 1, 'https://identifiers.org/aop.events/1752': 15, 'https://identifiers.org/aop.events/887': 20, 'https://identifiers.org/aop.events/1585': 8, 'https://identifiers.org/aop.events/214': 5, 'https://identifiers.org/aop.events/1271': 10, 'https://identifiers.org/aop.events/1087': 56, 'https://identifiers.org/aop.events/1538': 7, 'https://identifiers.org/aop.events/898': 38, 'https://identifiers.org/aop.events/195': 15, 'https://identifiers.org/aop.events/459': 15, 'https://identifiers.org/aop.events/341': 2, 'https://identifiers.org/aop.events/1670': 14, 'https://identifiers.org/aop.events/759': 4, 'https://identifiers.org/aop.events/1090': 66, 'https://identifiers.org/aop.events/344': 4, 'https://identifiers.org/aop.events/1841': 3, 'https://identifiers.org/aop.events/1820': 11, 'https://identifiers.org/aop.events/896': 7, 'https://identifiers.org/aop.events/1549': 17, 'https://identifiers.org/aop.events/357': 2, 'https://identifiers.org/aop.events/352': 48}
Step 61. The output of the n variable dictionary is saved as a dataframe and integrated as a separate column into a dataframe.
n_variable_dataframe6=pd.DataFrame.from_dict(variable_n_dictionary_count6,orient='index')
n_variable_dataframe6
0 | |
---|---|
https://identifiers.org/aop.events/486 | 15 |
https://identifiers.org/aop.events/875 | 15 |
https://identifiers.org/aop.events/2007 | 17 |
https://identifiers.org/aop.events/1495 | 29 |
https://identifiers.org/aop.events/105 | 31 |
... | ... |
https://identifiers.org/aop.events/1820 | 11 |
https://identifiers.org/aop.events/896 | 7 |
https://identifiers.org/aop.events/1549 | 17 |
https://identifiers.org/aop.events/357 | 2 |
https://identifiers.org/aop.events/352 | 48 |
98 rows × 1 columns
n_variable_dataframe6_reset = n_variable_dataframe6.reset_index()
n_variable_dataframe6_reset.columns = ['KEID', 'n']
n_variable_dataframe6_reset
KEID | n | |
---|---|---|
0 | https://identifiers.org/aop.events/486 | 15 |
1 | https://identifiers.org/aop.events/875 | 15 |
2 | https://identifiers.org/aop.events/2007 | 17 |
3 | https://identifiers.org/aop.events/1495 | 29 |
4 | https://identifiers.org/aop.events/105 | 31 |
... | ... | ... |
93 | https://identifiers.org/aop.events/1820 | 11 |
94 | https://identifiers.org/aop.events/896 | 7 |
95 | https://identifiers.org/aop.events/1549 | 17 |
96 | https://identifiers.org/aop.events/357 | 2 |
97 | https://identifiers.org/aop.events/352 | 48 |
98 rows × 2 columns
merged_dataframe6= pd.merge(mergeddataframeDEG, n_variable_dataframe6_reset, on='KEID')
Section 9.2. Calculation of variable B and variable b.
In this section, variable B and variable b are calculated.
Step 62. Variable B is calculated by taking the length of the dataframe which includes all genes in 1 DEG table.
B=len(The_Comparison6_DEG.index)
B
19751
Step 63. Variable b is calculated by taking the length of the dataframe which includes all genes in 1 DEG table with the condition for significance.
The_Comparison6_DEG_filtered=The_Comparison6_DEG[The_Comparison6_DEG['adj.P.Val'] < 0.05]
b=len(The_Comparison6_DEG_filtered)
b
3036
Section 9.3. Calculation of enrichment score and hypergeometric p-value
In this section, the enrichment score and hypergeometric p-value will be calculated. This requires the four variables of the enrichment score per KE for which the formula will be applied to and stored in an additional dataframe.
Step 64. The final dataframe will be created that contains the KEID and the four variables: variable N, variable n, variable B and variable b.
Final_dataframe_ES= merged_dataframe4.loc[:, ['KEID','N','n']]
Final_dataframe_ES['B']=pd.Series([19751 for x in range(len(Final_dataframe_ES.index))])
Final_dataframe_ES['b']=pd.Series([3036 for x in range(len(Final_dataframe_ES.index))])
Final_Dataframe_ES=Final_dataframe_ES.drop_duplicates(subset=['KEID'],keep='first')
Final_Dataframe_ES.reset_index(drop=True,inplace=True)
Copy_Final_DataFrame_ES=Final_Dataframe_ES.copy()
Step 65. The following for loop will be used to calculate the enrichment score for individual key events and the results will be saved as a separate column into the dataframe.
def calculate_Enrichment_Score(row):
return f"{(row['n']/row['N'])/(row['b']/row['B'])}"
Copy_Final_DataFrame_ES.loc[:,'Enrichmentscore']= Copy_Final_DataFrame_ES.apply(calculate_Enrichment_Score,axis=1)
Copy_Final_DataFrame_ES
KEID | N | n | B | b | Enrichmentscore | |
---|---|---|---|---|---|---|
0 | https://identifiers.org/aop.events/486 | 129 | 7 | 19751 | 3036 | 0.3530170256661662 |
1 | https://identifiers.org/aop.events/875 | 169 | 13 | 19751 | 3036 | 0.5004307286915983 |
2 | https://identifiers.org/aop.events/2007 | 184 | 11 | 19751 | 3036 | 0.38892170762444866 |
3 | https://identifiers.org/aop.events/1495 | 253 | 7 | 19751 | 3036 | 0.1799968233633812 |
4 | https://identifiers.org/aop.events/1668 | 156 | 5 | 19751 | 3036 | 0.20851280362149927 |
... | ... | ... | ... | ... | ... | ... |
81 | https://identifiers.org/aop.events/1841 | 17 | 1 | 19751 | 3036 | 0.38268232194063395 |
82 | https://identifiers.org/aop.events/1820 | 57 | 6 | 19751 | 3036 | 0.684799944525345 |
83 | https://identifiers.org/aop.events/896 | 82 | 2 | 19751 | 3036 | 0.15867315787782385 |
84 | https://identifiers.org/aop.events/1549 | 101 | 7 | 19751 | 3036 | 0.4508831317914401 |
85 | https://identifiers.org/aop.events/352 | 398 | 20 | 19751 | 3036 | 0.3269145463814461 |
86 rows × 6 columns
Step 66. The following for loop will be used to calculate the hypergeometric p-value for individual Key Events and save the result as a separate column into the dataframe. This requires some in between steps for manipulation of the dataframe.
p_value_dataframe6=[]
for index, row in Copy_Final_DataFrame_ES.iterrows():
M = row['B']
n = row['b']
N = row['N']
k = row['n']
hpd = ss.hypergeom(M, n, N)
p = hpd.pmf(k)
p_value_dataframe6.append(p)
Hypergeometricpvalue_dataframe6=pd.DataFrame(p_value_dataframe6)
Hypergeometricpvalue_dataframe6.columns= ['Hypergeometric p-value']
Hypergeometric p-value | |
---|---|
0 | 2.822035e-04 |
1 | 1.173261e-03 |
2 | 4.670726e-05 |
3 | 2.974437e-11 |
4 | 6.561125e-07 |
... | ... |
81 | 1.808467e-01 |
82 | 9.621510e-02 |
83 | 1.221305e-04 |
84 | 5.291469e-03 |
85 | 3.915659e-11 |
86 rows × 1 columns
merged_finaltable_C6=pd.concat([Copy_Final_DataFrame_ES,Hypergeometricpvalue_dataframe6],axis=1)
Section 9.4. Filtering the results for significant KEs
In this section, the results will be filtered to only include significant KEs. Significant KEs have an enrichment score above 1 and a hypergeometric p-value below 0.05.
Step 67. Lastly, we filter the results to showcase the significant KEs for the comparison: 6.
filteredversion_C6= merged_finaltable_C6[(merged_finaltable_C6['Enrichmentscore']>str(1))& (merged_finaltable_C6['Hypergeometric p-value'] < 0.05)]
filteredversion_C6
KEID | N | n | B | b | Enrichmentscore | Hypergeometric p-value | |
---|---|---|---|---|---|---|---|
29 | https://identifiers.org/aop.events/1815 | 58 | 14 | 19751 | 3036 | 1.5703171141701877 | 0.026893 |
Section 9.5. Calculation of percent gene overlap to ORA
Section 9.5.1 Creation of the significant KEs table
In this section, you merge the dataframes to retrieve the genes connected to only the significant KEs.
Step 68. The significant KE table is created using the significan KEs from the previous merggeddataframe_final.
significantKEID_genetable6=mergeddataframe_final2[(mergeddataframe_final2['KEID'] == 'https://identifiers.org/aop.events/1815')]
significantKEIDgenetable6=significantKEID_genetable6.drop(columns={'WPtitle','ID'})
KEID | gene | GENEID | |
---|---|---|---|
7162 | https://identifiers.org/aop.events/1815 | MBTPS1 | 8720 |
7163 | https://identifiers.org/aop.events/1815 | ATF4 | 468 |
7164 | https://identifiers.org/aop.events/1815 | ATF4 | 100089902 |
7165 | https://identifiers.org/aop.events/1815 | ATF4 | 100144302 |
7166 | https://identifiers.org/aop.events/1815 | MBTPS2 | 51360 |
7167 | https://identifiers.org/aop.events/1815 | NFE2L2 | 4780 |
7168 | https://identifiers.org/aop.events/1815 | HSPA5 | 3309 |
7169 | https://identifiers.org/aop.events/1815 | PPP1R15A | 23645 |
7170 | https://identifiers.org/aop.events/1815 | XBP1 | 7494 |
7171 | https://identifiers.org/aop.events/1815 | ATF6 | 22926 |
7172 | https://identifiers.org/aop.events/1815 | EIF2S1 | 1965 |
7173 | https://identifiers.org/aop.events/1815 | ERN1 | 2081 |
7174 | https://identifiers.org/aop.events/1815 | DDIT3 | 1649 |
7175 | https://identifiers.org/aop.events/1815 | EIF2AK3 | 9451 |
7176 | https://identifiers.org/aop.events/1815 | BBC3 | 27113 |
7177 | https://identifiers.org/aop.events/1815 | BBC3 | 782359 |
7178 | https://identifiers.org/aop.events/1815 | BBC3 | 100517403 |
7179 | https://identifiers.org/aop.events/1815 | TNFRSF10B | 8795 |
7180 | https://identifiers.org/aop.events/1815 | IL1B | 3553 |
7181 | https://identifiers.org/aop.events/1815 | TP53 | 7157 |
7182 | https://identifiers.org/aop.events/1815 | PMAIP1 | 5366 |
7183 | https://identifiers.org/aop.events/1815 | BID | 637 |
7184 | https://identifiers.org/aop.events/1815 | BID | 594852 |
7185 | https://identifiers.org/aop.events/1815 | TXNIP | 10628 |
7186 | https://identifiers.org/aop.events/1815 | BCL2L11 | 10018 |
7187 | https://identifiers.org/aop.events/1815 | BCL2 | 100049703 |
7188 | https://identifiers.org/aop.events/1815 | BCL2 | 596 |
7189 | https://identifiers.org/aop.events/1815 | RTCB | 51493 |
7190 | https://identifiers.org/aop.events/1815 | CASP2 | 835 |
7191 | https://identifiers.org/aop.events/1815 | MBTPS1 | 8720 |
7192 | https://identifiers.org/aop.events/1815 | ATF4 | 468 |
7193 | https://identifiers.org/aop.events/1815 | ATF4 | 100089902 |
7194 | https://identifiers.org/aop.events/1815 | ATF4 | 100144302 |
7195 | https://identifiers.org/aop.events/1815 | MBTPS2 | 51360 |
7196 | https://identifiers.org/aop.events/1815 | NFE2L2 | 4780 |
7197 | https://identifiers.org/aop.events/1815 | HSPA5 | 3309 |
7198 | https://identifiers.org/aop.events/1815 | PPP1R15A | 23645 |
7199 | https://identifiers.org/aop.events/1815 | XBP1 | 7494 |
7200 | https://identifiers.org/aop.events/1815 | ATF6 | 22926 |
7201 | https://identifiers.org/aop.events/1815 | EIF2S1 | 1965 |
7202 | https://identifiers.org/aop.events/1815 | ERN1 | 2081 |
7203 | https://identifiers.org/aop.events/1815 | DDIT3 | 1649 |
7204 | https://identifiers.org/aop.events/1815 | EIF2AK3 | 9451 |
7205 | https://identifiers.org/aop.events/1815 | BBC3 | 27113 |
7206 | https://identifiers.org/aop.events/1815 | BBC3 | 782359 |
7207 | https://identifiers.org/aop.events/1815 | BBC3 | 100517403 |
7208 | https://identifiers.org/aop.events/1815 | TNFRSF10B | 8795 |
7209 | https://identifiers.org/aop.events/1815 | IL1B | 3553 |
7210 | https://identifiers.org/aop.events/1815 | TP53 | 7157 |
7211 | https://identifiers.org/aop.events/1815 | PMAIP1 | 5366 |
7212 | https://identifiers.org/aop.events/1815 | BID | 637 |
7213 | https://identifiers.org/aop.events/1815 | BID | 594852 |
7214 | https://identifiers.org/aop.events/1815 | TXNIP | 10628 |
7215 | https://identifiers.org/aop.events/1815 | BCL2L11 | 10018 |
7216 | https://identifiers.org/aop.events/1815 | BCL2 | 100049703 |
7217 | https://identifiers.org/aop.events/1815 | BCL2 | 596 |
7218 | https://identifiers.org/aop.events/1815 | RTCB | 51493 |
7219 | https://identifiers.org/aop.events/1815 | CASP2 | 835 |
Section 9.5.2 Significant ORA pathway table plus splitting
In this section, the significant ORA pathway table is created.
Step 69. The significant ORA pathway table is created using the significant enriched patwhays identified from the ORA analysis. This requires data manipulation to restructure the table in a way that the individual genes for the enriched pathways are placed on individual rows.
datafile_ORA6 = pd.read_csv("C:/Users/shaki/Downloads/GSE44729_ORApathwaytable/Comparison 6-MA timepoint 2.txt", sep='\t')
datafileORA6=pd.DataFrame(datafile_ORA6)
filtereddatafileORA_6=datafileORA6[datafileORA6['Adjusted P-value'] < 0.05]
Gene_set | Term | P-value | Adjusted P-value | Old P-value | Old adjusted P-value | Odds Ratio | Combined Score | Genes | |
---|---|---|---|---|---|---|---|---|---|
0 | WikiPathways_2024_Human | Cholesterol Metab With Bloch And Kandutsch Rus... | 6.999085e-08 | 0.000046 | 0 | 0 | 6.547847 | 107.87510 | MVK;HMGCS1;ELOVL3;CYP51A1;HMGCR;LSS;ACAT2;TM7S... |
1 | WikiPathways_2024_Human | Cholesterol Biosynthesis Pathway WP197 | 1.248168e-07 | 0.000046 | 0 | 0 | 24.182140 | 384.40950 | SQLE;NSDHL;MVK;HMGCS1;CYP51A1;PMVK;HMGCR;DHCR7... |
2 | WikiPathways_2024_Human | Cholesterol Biosynthesis Pathway In Hepatocyte... | 4.621708e-07 | 0.000114 | 0 | 0 | 6.464158 | 94.29481 | MVK;HMGCS1;ELOVL3;CYP51A1;HMGCR;LSS;ACAT2;TM7S... |
3 | WikiPathways_2024_Human | Enterocyte Cholesterol Metabolism WP5333 | 2.091167e-06 | 0.000388 | 0 | 0 | 6.662888 | 87.13584 | MVK;HMGCS1;CYP51A1;APOA1;HMGCR;LSS;ACAT2;TM7SF... |
4 | WikiPathways_2024_Human | Cholesterol Synthesis Disorders WP5193 | 1.937190e-05 | 0.002875 | 0 | 0 | 10.738850 | 116.53460 | SQLE;MVK;HMGCS1;CYP51A1;PMVK;HMGCR;DHCR7;LSS |
5 | WikiPathways_2024_Human | Spinal Cord Injury WP2431 | 2.896157e-05 | 0.003582 | 0 | 0 | 2.878078 | 30.07459 | RTN4R;ANXA1;IL1R1;GADD45A;FOS;NTN1;IL2;AQP1;FK... |
6 | WikiPathways_2024_Human | G1 To S Cell Cycle Control WP45 | 5.037775e-05 | 0.005340 | 0 | 0 | 3.938063 | 38.97092 | PCNA;CCNH;GADD45A;PRIM1;CDC25A;CCNE2;CREB3L4;C... |
7 | WikiPathways_2024_Human | Vitamin B12 Metabolism WP1533 | 6.646654e-05 | 0.006165 | 0 | 0 | 4.071351 | 39.16156 | FGB;MTRR;SERPINE1;SAA4;APOA1;MTHFR;IFNG;CBS;IL... |
8 | WikiPathways_2024_Human | Mevalonate Pathway WP3963 | 8.247087e-05 | 0.006799 | 0 | 0 | 26.808190 | 252.07920 | MVK;HMGCS1;PMVK;HMGCR;ACAT2 |
9 | WikiPathways_2024_Human | Folate Metabolism WP176 | 1.283462e-04 | 0.009523 | 0 | 0 | 3.377096 | 30.26142 | FGB;MTRR;SERPINE1;SAA4;APOA1;MTHFR;MTHFS;IL2;I... |
10 | WikiPathways_2024_Human | Retinoblastoma Gene In Cancer WP2446 | 1.875368e-04 | 0.012650 | 0 | 0 | 2.982185 | 25.59172 | CDT1;RRM1;PCNA;RRM2;PRIM1;SMC1A;TYMS;CDC25A;FA... |
11 | WikiPathways_2024_Human | Axon Guidance WP5289 | 2.217143e-04 | 0.013709 | 0 | 0 | 3.188949 | 26.83220 | NRP1;BMPR2;DCC;ILK;CXCR4;UNC5D;ENAH;EFNA1;EFNB... |
12 | WikiPathways_2024_Human | Selenium Micronutrient Network WP15 | 3.126095e-04 | 0.017843 | 0 | 0 | 3.074716 | 24.81467 | FGB;SERPINE1;SAA4;APOA1;MTHFR;PTGS1;PRDX4;IFNG... |
13 | WikiPathways_2024_Human | Mevalonate Arm Of Cholesterol Biosynthesis Pat... | 3.926396e-04 | 0.020810 | 0 | 0 | 9.194296 | 72.10736 | HMGCL;MVK;HMGCS1;PMVK;HMGCR;ACAT2 |
14 | WikiPathways_2024_Human | Development Of Ureteric Derived Collecting Sys... | 4.950783e-04 | 0.022525 | 0 | 0 | 3.408915 | 25.94455 | GDF11;RARG;BMPR2;FST;ILK;GLI1;ETV4;GLI2;BMP2;S... |
15 | WikiPathways_2024_Human | DNA Replication WP466 | 5.106286e-04 | 0.022525 | 0 | 0 | 4.296605 | 32.56770 | POLD4;CDT1;POLA1;PCNA;PRIM1;RPA3;MCM4;MCM5;MCM... |
16 | WikiPathways_2024_Human | IL1 And Megakaryocytes In Obesity WP2865 | 5.945121e-04 | 0.022525 | 0 | 0 | 5.367043 | 39.86516 | SELENBP1;IFNG;IL1R1;IL1B;CCL2;TIMP1;PLA2G7;HBEGF |
17 | WikiPathways_2024_Human | TAR Syndrome WP5362 | 5.982359e-04 | 0.022525 | 0 | 0 | 3.327566 | 24.69561 | ZFHX3;PEX19;CXCR4;CLCN3;PDZK1IP1;DNM1;SLK;IFNG... |
18 | WikiPathways_2024_Human | Cholesterol Metabolism WP5304 | 6.103901e-04 | 0.022525 | 0 | 0 | 2.987853 | 22.11434 | MVK;HMGCS1;CYP51A1;PCSK9;APOA1;HMGCR;LSS;ACAT2... |
19 | WikiPathways_2024_Human | COVID 19 Adverse Outcome Pathway WP4891 | 6.375029e-04 | 0.022525 | 0 | 0 | 8.044563 | 59.19151 | CXCL10;IL2RA;IL1B;CCL2;IL2;AGT |
20 | WikiPathways_2024_Human | Omega 9 Fatty Acid Synthesis WP4724 | 6.375029e-04 | 0.022525 | 0 | 0 | 8.044563 | 59.19151 | FADS2;SCD;ELOVL3;ACOT2;ELOVL6;FADS1 |
21 | WikiPathways_2024_Human | Ciliopathies WP4803 | 7.740410e-04 | 0.026106 | 0 | 0 | 2.229761 | 15.97375 | DYNC2H1;TUB;NEK9;ARL6;CCDC103;WDR19;CCDC28B;GL... |
22 | WikiPathways_2024_Human | 7 Oxo C And 7 Beta HC Pathways WP5064 | 8.092587e-04 | 0.026107 | 0 | 0 | 5.051055 | 35.96044 | CYP27A1;AMACR;ACOX2;ACOT11;ACOT2;ACOT1;DHCR7;S... |
23 | WikiPathways_2024_Human | Base Excision Repair WP4752 | 8.522901e-04 | 0.026350 | 0 | 0 | 4.392370 | 31.04344 | POLB;SMUG1;POLD4;PCNA;LIG1;OGG1;PNKP;APEX1;XRCC1 |
24 | WikiPathways_2024_Human | Fluoropyrimidine Activity WP1601 | 1.395019e-03 | 0.041404 | 0 | 0 | 4.025893 | 26.46963 | SMUG1;RRM1;RRM2;PPAT;MTHFR;UPP1;TYMS;TYMP;ABCG2 |
dropped_datafileORA_df6=filtereddatafileORA_6.drop(['Adjusted P-value','Odds Ratio','Old P-value','Gene_set','P-value','Old adjusted P-value','Combined Score'],axis=1)
droppeddatafileORAdf6=dropped_datafileORA_df6.copy()
droppeddatafileORAdf6['Genes']= droppeddatafileORAdf6['Genes'].replace({';':','},regex=True)
df6_ORApathwaytable=droppeddatafileORAdf6.copy()
df6_ORApathwaytable['Genes'] = df6_ORApathwaytable['Genes'].astype(str)
df6_ORApathwaytable['Genes'] = df6_ORApathwaytable['Genes'].str.split(',')
exploded_df6_ORApathwaytable = df6_ORApathwaytable.explode('Genes', ignore_index=True)
Section 9.5.3 For loop to get overlapping genes
In this section, the number of overlapping genes between the significant enrichment score-based Key Events and enriched pathways from ORA are calculated.
Step 70. Next, two sets are created by converting the significant KE table and ORA pathway table into dictionaries where the values of the genes are grouped together per key. This is followed by running a for loop to calculate the number of overlapping genes along with the symbols.
ORA_gene_sets6 = exploded_df6_ORApathwaytable.groupby('Term')['Genes'].apply(set).to_dict()
SignificantKE_gene_sets6= significantKEIDgenetable6.groupby('KEID')['gene'].apply(set).to_dict()
overlapping_genes_betweenORA_and_significantKEs6 = {}
for term, ORA_genes in ORA_gene_sets6.items():
for KEID, KEID_genes in SignificantKE_gene_sets6.items():
overlap = ORA_genes.intersection(KEID_genes)
print(f"{term} x {KEID}: {len(overlap)} overlaps")
overlapping_genes_betweenORA_and_significantKEs6[(term, KEID)] = {
'overlapping genes': overlap,
'number of genes that overlap': len(overlap)
}
if overlapping_genes_betweenORA_and_significantKEs6:
print("\ntitle of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:")
for (term, KEID), result in overlapping_genes_betweenORA_and_significantKEs6.items():
print(f"Term: {term}, KEID: {KEID}, Title of overlapping gene(s): {result['overlapping genes']}, number: {result['number of genes that overlap']}")
else:
print("No overlapping genes")
7 Oxo C And 7 Beta HC Pathways WP5064 x https://identifiers.org/aop.events/1815: 0 overlaps
Axon Guidance WP5289 x https://identifiers.org/aop.events/1815: 0 overlaps
Base Excision Repair WP4752 x https://identifiers.org/aop.events/1815: 0 overlaps
COVID 19 Adverse Outcome Pathway WP4891 x https://identifiers.org/aop.events/1815: 1 overlaps
Cholesterol Biosynthesis Pathway In Hepatocytes WP5329 x https://identifiers.org/aop.events/1815: 0 overlaps
Cholesterol Biosynthesis Pathway WP197 x https://identifiers.org/aop.events/1815: 0 overlaps
Cholesterol Metab With Bloch And Kandutsch Russell Pathways WP4718 x https://identifiers.org/aop.events/1815: 0 overlaps
Cholesterol Metabolism WP5304 x https://identifiers.org/aop.events/1815: 0 overlaps
Cholesterol Synthesis Disorders WP5193 x https://identifiers.org/aop.events/1815: 0 overlaps
Ciliopathies WP4803 x https://identifiers.org/aop.events/1815: 0 overlaps
DNA Replication WP466 x https://identifiers.org/aop.events/1815: 0 overlaps
Development Of Ureteric Derived Collecting System WP5053 x https://identifiers.org/aop.events/1815: 0 overlaps
Enterocyte Cholesterol Metabolism WP5333 x https://identifiers.org/aop.events/1815: 0 overlaps
Fluoropyrimidine Activity WP1601 x https://identifiers.org/aop.events/1815: 0 overlaps
Folate Metabolism WP176 x https://identifiers.org/aop.events/1815: 1 overlaps
G1 To S Cell Cycle Control WP45 x https://identifiers.org/aop.events/1815: 0 overlaps
IL1 And Megakaryocytes In Obesity WP2865 x https://identifiers.org/aop.events/1815: 1 overlaps
Mevalonate Arm Of Cholesterol Biosynthesis Pathway WP4190 x https://identifiers.org/aop.events/1815: 0 overlaps
Mevalonate Pathway WP3963 x https://identifiers.org/aop.events/1815: 0 overlaps
Omega 9 Fatty Acid Synthesis WP4724 x https://identifiers.org/aop.events/1815: 0 overlaps
Retinoblastoma Gene In Cancer WP2446 x https://identifiers.org/aop.events/1815: 0 overlaps
Selenium Micronutrient Network WP15 x https://identifiers.org/aop.events/1815: 1 overlaps
Spinal Cord Injury WP2431 x https://identifiers.org/aop.events/1815: 1 overlaps
TAR Syndrome WP5362 x https://identifiers.org/aop.events/1815: 0 overlaps
Vitamin B12 Metabolism WP1533 x https://identifiers.org/aop.events/1815: 1 overlaps
title of Overlapping Gene(s) and the number between enriched pathways from ORA and significant KEs:
Term: 7 Oxo C And 7 Beta HC Pathways WP5064, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Axon Guidance WP5289, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Base Excision Repair WP4752, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: COVID 19 Adverse Outcome Pathway WP4891, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'IL1B'}, number: 1
Term: Cholesterol Biosynthesis Pathway In Hepatocytes WP5329, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Cholesterol Biosynthesis Pathway WP197, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Cholesterol Metab With Bloch And Kandutsch Russell Pathways WP4718, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Cholesterol Metabolism WP5304, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Cholesterol Synthesis Disorders WP5193, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Ciliopathies WP4803, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: DNA Replication WP466, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Development Of Ureteric Derived Collecting System WP5053, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Enterocyte Cholesterol Metabolism WP5333, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Fluoropyrimidine Activity WP1601, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Folate Metabolism WP176, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'IL1B'}, number: 1
Term: G1 To S Cell Cycle Control WP45, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: IL1 And Megakaryocytes In Obesity WP2865, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'IL1B'}, number: 1
Term: Mevalonate Arm Of Cholesterol Biosynthesis Pathway WP4190, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Mevalonate Pathway WP3963, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Omega 9 Fatty Acid Synthesis WP4724, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Retinoblastoma Gene In Cancer WP2446, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Selenium Micronutrient Network WP15, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'IL1B'}, number: 1
Term: Spinal Cord Injury WP2431, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'IL1B'}, number: 1
Term: TAR Syndrome WP5362, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): set(), number: 0
Term: Vitamin B12 Metabolism WP1533, KEID: https://identifiers.org/aop.events/1815, Title of overlapping gene(s): {'IL1B'}, number: 1
Section 9.5.4 Tabulation gene overlap
In this section, a table is created that contains the number of overlapping genes and number of total genes in preparation for section 10.5.5.
final_geneoverlaptable_C6=pd.DataFrame.from_dict(overlapping_genes_betweenORA_and_significantKEs6,orient='index')
Section 9.5.5 Percent overlap calculation
In this section, the percent overlap for the genesets are calculated.
Step 71. Lastly, the percent overlap is calculated and add the result as a column to the dataframe. This is first done by running a for loop to calculate the total number of genes belonging to the enriched pathways of ORA.
variable_count6= {}
for index, row in exploded_df6_ORApathwaytable.iterrows():
unique_KE = row['Term']
gene_expression_value = row['Genes']
if unique_KE not in variable_count6:
variable_count6[unique_KE] = 1
else:
variable_count6[unique_KE] += 1
print("The total number of genes: ")
print(variable_count6)
The total number of genes:
{'Cholesterol Metab With Bloch And Kandutsch Russell Pathways WP4718': 17, 'Cholesterol Biosynthesis Pathway WP197': 9, 'Cholesterol Biosynthesis Pathway In Hepatocytes WP5329': 15, 'Enterocyte Cholesterol Metabolism WP5333': 13, 'Cholesterol Synthesis Disorders WP5193': 8, 'Spinal Cord Injury WP2431': 24, 'G1 To S Cell Cycle Control WP45': 15, 'Vitamin B12 Metabolism WP1533': 14, 'Mevalonate Pathway WP3963': 5, 'Folate Metabolism WP176': 16, 'Retinoblastoma Gene In Cancer WP2446': 18, 'Axon Guidance WP5289': 16, 'Selenium Micronutrient Network WP15': 16, 'Mevalonate Arm Of Cholesterol Biosynthesis Pathway WP4190': 6, 'Development Of Ureteric Derived Collecting System WP5053': 13, 'DNA Replication WP466': 10, 'IL1 And Megakaryocytes In Obesity WP2865': 8, 'TAR Syndrome WP5362': 13, 'Cholesterol Metabolism WP5304': 15, 'COVID 19 Adverse Outcome Pathway WP4891': 6, 'Omega 9 Fatty Acid Synthesis WP4724': 6, 'Ciliopathies WP4803': 24, '7 Oxo C And 7 Beta HC Pathways WP5064': 8, 'Base Excision Repair WP4752': 9, 'Fluoropyrimidine Activity WP1601': 9}
Step 72. The result is converted into a dataframe and added to the final dataframe. This is followed by some data manipulation prior to calculation of gene set overlap.
variable_count_df6=pd.DataFrame.from_dict(variable_count6,orient='index')
reset_variable_count_df6 = variable_count_df6.reset_index()
reset_variable_count_df6.columns = ['Term', 'Total number of genes']
Genesetoverlaptable_C6=final_geneoverlaptable_C6.reset_index(level=[1])
Genesetoverlaptable_C6.reset_index(inplace=True)
Genesetoverlaptable_C6.columns= ['Term','KEID','overlapping genes','number of genes that overlap']
tabulation_C6=pd.merge(reset_variable_count_df6,Genesetoverlaptable_C6, on='Term')
def calculate_Genesetoverlap_Score(row):
return f"{(row['number of genes that overlap']/row['Total number of genes'])*100}"
tabulation_C6.loc[:,'Percent geneset overlap']= tabulation_C6.apply(calculate_Genesetoverlap_Score, axis=1)
tabulation_C6
Term | Total number of genes | KEID | overlapping genes | number of genes that overlap | Percent geneset overlap | |
---|---|---|---|---|---|---|
0 | Cholesterol Metab With Bloch And Kandutsch Rus... | 17 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
1 | Cholesterol Biosynthesis Pathway WP197 | 9 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
2 | Cholesterol Biosynthesis Pathway In Hepatocyte... | 15 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
3 | Enterocyte Cholesterol Metabolism WP5333 | 13 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
4 | Cholesterol Synthesis Disorders WP5193 | 8 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
5 | Spinal Cord Injury WP2431 | 24 | https://identifiers.org/aop.events/1815 | {IL1B} | 1 | 4.166666666666666 |
6 | G1 To S Cell Cycle Control WP45 | 15 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
7 | Vitamin B12 Metabolism WP1533 | 14 | https://identifiers.org/aop.events/1815 | {IL1B} | 1 | 7.142857142857142 |
8 | Mevalonate Pathway WP3963 | 5 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
9 | Folate Metabolism WP176 | 16 | https://identifiers.org/aop.events/1815 | {IL1B} | 1 | 6.25 |
10 | Retinoblastoma Gene In Cancer WP2446 | 18 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
11 | Axon Guidance WP5289 | 16 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
12 | Selenium Micronutrient Network WP15 | 16 | https://identifiers.org/aop.events/1815 | {IL1B} | 1 | 6.25 |
13 | Mevalonate Arm Of Cholesterol Biosynthesis Pat... | 6 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
14 | Development Of Ureteric Derived Collecting Sys... | 13 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
15 | DNA Replication WP466 | 10 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
16 | IL1 And Megakaryocytes In Obesity WP2865 | 8 | https://identifiers.org/aop.events/1815 | {IL1B} | 1 | 12.5 |
17 | TAR Syndrome WP5362 | 13 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
18 | Cholesterol Metabolism WP5304 | 15 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
19 | COVID 19 Adverse Outcome Pathway WP4891 | 6 | https://identifiers.org/aop.events/1815 | {IL1B} | 1 | 16.666666666666664 |
20 | Omega 9 Fatty Acid Synthesis WP4724 | 6 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
21 | Ciliopathies WP4803 | 24 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
22 | 7 Oxo C And 7 Beta HC Pathways WP5064 | 8 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
23 | Base Excision Repair WP4752 | 9 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
24 | Fluoropyrimidine Activity WP1601 | 9 | https://identifiers.org/aop.events/1815 | {} | 0 | 0.0 |
Section 10: Metadadata
Step 73. At last, the metadata belonging to this Jupyter Notebook is displayed which contains the version numbers of packages and system-set-up for interested users. This requires the usage of packages:Watermark and print_versions.
%load_ext watermark
!pip install print-versions
Requirement already satisfied: print-versions in c:\users\shaki\anaconda3\lib\site-packages (0.1.0)
%watermark
Last updated: 2025-06-03T11:28:16.561497+02:00
Python implementation: CPython
Python version : 3.12.3
IPython version : 8.25.0
Compiler : MSC v.1938 64 bit (AMD64)
OS : Windows
Release : 11
Machine : AMD64
Processor : Intel64 Family 6 Model 140 Stepping 1, GenuineIntel
CPU cores : 8
Architecture: 64bit
from print_versions import print_versions
print_versions(globals())
pandas==2.2.3
json==2.0.9
ipykernel==6.28.0
numpy==1.26.4
scipy==1.13.1
py4cytoscape==1.9.0
References:
- Martens M, Meuleman AB, Kearns J, de Windt C, Evelo CT, Willighagen EL. Molecular Adverse Outcome Pathways: towards the implementation of transcriptomics data in risk assessments. bioRxiv. 2023:2023.03.02.530766.
- How can I iterate over rows in a Pandas DataFrame? [Internet]. Stack Overflow. Available from: https://stackoverflow.com/questions/16476924/how-can-i-iterate-over-rows-in-a-pandas-dataframe
- Python - Loop Dictionaries [Internet]. www.w3schools.com. Available from: https://www.w3schools.com/python/python_dictionaries_loop.asp
- Priya. apply(set) to two columns in a pandas dataframe [Internet]. Stack Overflow. 2018. Available from: https://stackoverflow.com/questions/52367388/applyset-to-two-columns-in-a-pandas-dataframe
- amnesic. Converting pandas dataframe to dictionary with same keys over multiple rows \[Internet\]. Stack Overflow. 2022. Available from: https://stackoverflow.com/questions/71006325/converting-pandas-dataframe-to-dictionary-with-same-keys-over-multiple-rows/71006478#71006478
- SuperDougDougy. GroupBy results to dictionary of lists [Internet]. Stack Overflow. 2015. Available from: https://stackoverflow.com/questions/29876184/groupby-results-to-dictionary-of-lists%E2%80%8C